LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4HTJ8_LEIIN
TriTrypDb:
LINF_080010100
Length:
362

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HTJ8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HTJ8

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 118 122 PF00656 0.790
CLV_NRD_NRD_1 160 162 PF00675 0.716
CLV_NRD_NRD_1 285 287 PF00675 0.713
CLV_NRD_NRD_1 315 317 PF00675 0.699
CLV_NRD_NRD_1 335 337 PF00675 0.389
CLV_NRD_NRD_1 350 352 PF00675 0.460
CLV_NRD_NRD_1 4 6 PF00675 0.747
CLV_NRD_NRD_1 59 61 PF00675 0.746
CLV_NRD_NRD_1 80 82 PF00675 0.605
CLV_PCSK_KEX2_1 160 162 PF00082 0.716
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S5H654 Leishmania donovani 98% 99%
A4H5B7 Leishmania braziliensis 49% 95%
E9AMC9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 72% 90%
Q4QIB9 Leishmania major 82% 99%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS