Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Tim10/DDP family zinc finger containing protein - putative

Species:

Leishmania infantum

UniProt:

A4HTI4_LEIIN

TriTrypDb:

LINF_080008300

Length:

Annotations

Annotations by Jardim et al.

Intracellular protein trafficking, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HTI4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HTI4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	58	60	PF00675	0.318
DEG_Nend_UBRbox_3	1	3	PF02207	0.483
LIG_EH1_1	65	73	PF00400	0.301
LIG_FHA_1	73	79	PF00498	0.417
LIG_FHA_2	35	41	PF00498	0.319
LIG_LIR_Gen_1	12	22	PF02991	0.343
LIG_LIR_Nem_3	18	22	PF02991	0.346
LIG_Pex14_1	28	32	PF04695	0.301
LIG_SH2_STAP1	32	36	PF00017	0.414
LIG_SH2_STAT3	32	35	PF00017	0.417
LIG_SUMO_SIM_anti_2	67	73	PF11976	0.417
LIG_SUMO_SIM_par_1	67	73	PF11976	0.417
MOD_CK1_1	34	40	PF00069	0.417
MOD_CK2_1	34	40	PF00069	0.342
MOD_GlcNHglycan	72	75	PF01048	0.417
MOD_PIKK_1	31	37	PF00454	0.417
MOD_Plk_2-3	12	18	PF00069	0.294
MOD_Plk_4	12	18	PF00069	0.328
MOD_Plk_4	67	73	PF00069	0.417
MOD_SUMO_rev_2	45	51	PF00179	0.265
TRG_DiLeu_BaEn_1	67	72	PF01217	0.301
TRG_ENDOCYTIC_2	14	17	PF00928	0.344
TRG_Pf-PMV_PEXEL_1	76	80	PF00026	0.539

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ICB2	Leptomonas seymouri	67%	99%
A0A0S4KET4	Bodo saltans	59%	96%
A0A3S5H643	Leishmania donovani	100%	100%
C9ZPK3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	68%	100%
E9AMB2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
Q4QID6	Leishmania major	97%	100%
V5DI02	Trypanosoma cruzi	63%	100%