Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HTG8_LEIIN

TriTrypDb:

LINF_080006700

Length:

644

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 5
NetGPI	no	yes: 0, no: 6

Show entries

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	7
GO:0042995	cell projection	2	7
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0110165	cellular anatomical entity	1	7
GO:0120025	plasma membrane bounded cell projection	3	7

Previous1Next

Expansion

Sequence features

A4HTG8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HTG8

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006950	response to stress	2	5
GO:0006952	defense response	3	5
GO:0050896	response to stimulus	1	5

Previous1Next

Could not find GO molecular_function term for this entry.

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	537	541	PF00656	0.445
CLV_MEL_PAP_1	578	584	PF00089	0.586
CLV_NRD_NRD_1	170	172	PF00675	0.687
CLV_NRD_NRD_1	230	232	PF00675	0.591
CLV_NRD_NRD_1	29	31	PF00675	0.621
CLV_NRD_NRD_1	314	316	PF00675	0.706
CLV_NRD_NRD_1	317	319	PF00675	0.641
CLV_NRD_NRD_1	341	343	PF00675	0.503
CLV_NRD_NRD_1	373	375	PF00675	0.498
CLV_NRD_NRD_1	634	636	PF00675	0.609

Previous1 2 3 4 5…25Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P939	Leptomonas seymouri	46%	98%
A0A3S5H632	Leishmania donovani	100%	100%
A4H584	Leishmania braziliensis	75%	100%
E9AM96	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	97%
Q4QIF2	Leishmania major	92%	100%

Previous1Next