LeishMANIAdb
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DUF1279 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
DUF1279 domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4HTG7_LEIIN
TriTrypDb:
LINF_080006600
Length:
233

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2
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Expansion

Sequence features

A4HTG7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HTG7

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 26 28 PF00675 0.519
CLV_PCSK_KEX2_1 220 222 PF00082 0.645
CLV_PCSK_KEX2_1 26 28 PF00082 0.518
CLV_PCSK_PC1ET2_1 220 222 PF00082 0.645
CLV_PCSK_SKI1_1 175 179 PF00082 0.570
CLV_PCSK_SKI1_1 220 224 PF00082 0.720
DEG_APCC_DBOX_1 174 182 PF00400 0.374
DEG_Nend_Nbox_1 1 3 PF02207 0.763
DOC_CDC14_PxL_1 199 207 PF14671 0.427
DOC_CYCLIN_yCln2_LP_2 205 211 PF00134 0.503
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IAL2 Leptomonas seymouri 47% 100%
A0A3S7WQ61 Leishmania donovani 100% 100%
A4H583 Leishmania braziliensis 72% 100%
C9ZPP7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 39% 100%
E9AM95 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
Q4QIF3 Leishmania major 91% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS