Putative DNA repair protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA repair protein - putative

Species:

Leishmania infantum

UniProt:

A4HTG5_LEIIN

TriTrypDb:

LINF_080006400

Length:

1260

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0000109	nucleotide-excision repair complex	3	1
GO:0000110	nucleotide-excision repair factor 1 complex	4	1
GO:0032991	protein-containing complex	1	1
GO:0140513	nuclear protein-containing complex	2	1

Expansion

Sequence features

A4HTG5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HTG5

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	11
GO:0006259	DNA metabolic process	4	11
GO:0006725	cellular aromatic compound metabolic process	3	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0009987	cellular process	1	11
GO:0034641	cellular nitrogen compound metabolic process	3	11
GO:0043170	macromolecule metabolic process	3	11
GO:0044237	cellular metabolic process	2	11
GO:0044238	primary metabolic process	2	11
GO:0044260	obsolete cellular macromolecule metabolic process	3	11
GO:0046483	heterocycle metabolic process	3	11
GO:0071704	organic substance metabolic process	2	11
GO:0090304	nucleic acid metabolic process	4	11
GO:1901360	organic cyclic compound metabolic process	3	11
GO:0000712	resolution of meiotic recombination intermediates	4	1
GO:0000724	double-strand break repair via homologous recombination	7	1
GO:0000725	recombinational repair	6	1
GO:0006281	DNA repair	5	1
GO:0006289	nucleotide-excision repair	6	1
GO:0006296	obsolete nucleotide-excision repair, DNA incision, 5'-to lesion	7	1
GO:0006302	double-strand break repair	6	1
GO:0006310	DNA recombination	5	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0022402	cell cycle process	2	1
GO:0022414	reproductive process	1	1
GO:0033554	cellular response to stress	3	1
GO:0033683	obsolete nucleotide-excision repair, DNA incision	6	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1
GO:0061982	meiosis I cell cycle process	3	1
GO:0090305	nucleic acid phosphodiester bond hydrolysis	5	1
GO:1901255	nucleotide-excision repair involved in interstrand cross-link repair	7	1
GO:1903046	meiotic cell cycle process	2	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	11
GO:0003677	DNA binding	4	11
GO:0003824	catalytic activity	1	11
GO:0004518	nuclease activity	4	11
GO:0005488	binding	1	11
GO:0016787	hydrolase activity	2	11
GO:0016788	hydrolase activity, acting on ester bonds	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:1901363	heterocyclic compound binding	2	11
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	6	1
GO:0003684	damaged DNA binding	5	1
GO:0003697	single-stranded DNA binding	5	1
GO:0004519	endonuclease activity	5	1
GO:0004520	DNA endonuclease activity	5	1
GO:0004536	DNA nuclease activity	4	1
GO:0140097	catalytic activity, acting on DNA	3	1
GO:0140640	catalytic activity, acting on a nucleic acid	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	29	33	PF00656	0.541
CLV_C14_Caspase3-7	423	427	PF00656	0.547
CLV_C14_Caspase3-7	550	554	PF00656	0.740
CLV_C14_Caspase3-7	752	756	PF00656	0.731
CLV_NRD_NRD_1	1009	1011	PF00675	0.615
CLV_NRD_NRD_1	1053	1055	PF00675	0.402
CLV_NRD_NRD_1	1077	1079	PF00675	0.320
CLV_NRD_NRD_1	1101	1103	PF00675	0.357
CLV_NRD_NRD_1	158	160	PF00675	0.409
CLV_NRD_NRD_1	268	270	PF00675	0.641
CLV_NRD_NRD_1	453	455	PF00675	0.397
CLV_NRD_NRD_1	456	458	PF00675	0.410
CLV_NRD_NRD_1	476	478	PF00675	0.598
CLV_NRD_NRD_1	480	482	PF00675	0.681
CLV_NRD_NRD_1	616	618	PF00675	0.498
CLV_NRD_NRD_1	619	621	PF00675	0.555
CLV_NRD_NRD_1	66	68	PF00675	0.542
CLV_NRD_NRD_1	665	667	PF00675	0.495
CLV_NRD_NRD_1	728	730	PF00675	0.781
CLV_NRD_NRD_1	739	741	PF00675	0.671
CLV_NRD_NRD_1	753	755	PF00675	0.687
CLV_PCSK_FUR_1	454	458	PF00082	0.451
CLV_PCSK_KEX2_1	1053	1055	PF00082	0.373
CLV_PCSK_KEX2_1	158	160	PF00082	0.409
CLV_PCSK_KEX2_1	268	270	PF00082	0.641
CLV_PCSK_KEX2_1	453	455	PF00082	0.399
CLV_PCSK_KEX2_1	456	458	PF00082	0.406
CLV_PCSK_KEX2_1	476	478	PF00082	0.543
CLV_PCSK_KEX2_1	480	482	PF00082	0.639
CLV_PCSK_KEX2_1	518	520	PF00082	0.540
CLV_PCSK_KEX2_1	557	559	PF00082	0.607
CLV_PCSK_KEX2_1	616	618	PF00082	0.523
CLV_PCSK_KEX2_1	66	68	PF00082	0.542
CLV_PCSK_KEX2_1	665	667	PF00082	0.495
CLV_PCSK_KEX2_1	728	730	PF00082	0.790
CLV_PCSK_KEX2_1	738	740	PF00082	0.706
CLV_PCSK_KEX2_1	753	755	PF00082	0.630
CLV_PCSK_PC1ET2_1	518	520	PF00082	0.540
CLV_PCSK_PC1ET2_1	557	559	PF00082	0.607
CLV_PCSK_PC7_1	476	482	PF00082	0.597
CLV_PCSK_PC7_1	612	618	PF00082	0.517
CLV_PCSK_SKI1_1	1035	1039	PF00082	0.513
CLV_PCSK_SKI1_1	293	297	PF00082	0.467
CLV_PCSK_SKI1_1	397	401	PF00082	0.605
CLV_PCSK_SKI1_1	405	409	PF00082	0.490
CLV_PCSK_SKI1_1	443	447	PF00082	0.493
CLV_PCSK_SKI1_1	612	616	PF00082	0.511
CLV_PCSK_SKI1_1	728	732	PF00082	0.669
CLV_PCSK_SKI1_1	914	918	PF00082	0.494
DEG_APCC_DBOX_1	250	258	PF00400	0.458
DEG_APCC_DBOX_1	557	565	PF00400	0.712
DEG_APCC_DBOX_1	918	926	PF00400	0.517
DEG_COP1_1	841	849	PF00400	0.561
DEG_ODPH_VHL_1	186	198	PF01847	0.511
DEG_SPOP_SBC_1	548	552	PF00917	0.725
DEG_SPOP_SBC_1	564	568	PF00917	0.733
DOC_CDC14_PxL_1	1022	1030	PF14671	0.650
DOC_CDC14_PxL_1	784	792	PF14671	0.737
DOC_CKS1_1	526	531	PF01111	0.600
DOC_CKS1_1	814	819	PF01111	0.633
DOC_CYCLIN_RxL_1	852	862	PF00134	0.534
DOC_CYCLIN_yCln2_LP_2	1023	1029	PF00134	0.650
DOC_CYCLIN_yCln2_LP_2	116	122	PF00134	0.454
DOC_CYCLIN_yCln2_LP_2	814	820	PF00134	0.698
DOC_MAPK_DCC_7	1053	1063	PF00069	0.334
DOC_MAPK_gen_1	1053	1061	PF00069	0.378
DOC_MAPK_gen_1	1102	1110	PF00069	0.355
DOC_MAPK_gen_1	158	164	PF00069	0.432
DOC_MAPK_gen_1	265	273	PF00069	0.603
DOC_MAPK_gen_1	518	526	PF00069	0.671
DOC_MAPK_gen_1	63	73	PF00069	0.527
DOC_MAPK_gen_1	823	831	PF00069	0.513
DOC_MAPK_HePTP_8	1051	1063	PF00069	0.335
DOC_MAPK_MEF2A_6	1054	1063	PF00069	0.322
DOC_MAPK_MEF2A_6	209	216	PF00069	0.400
DOC_MAPK_MEF2A_6	939	947	PF00069	0.465
DOC_MAPK_RevD_3	943	959	PF00069	0.532
DOC_PP1_RVXF_1	1033	1039	PF00149	0.476
DOC_PP1_RVXF_1	1137	1143	PF00149	0.446
DOC_PP1_RVXF_1	251	257	PF00149	0.505
DOC_PP1_RVXF_1	403	410	PF00149	0.563
DOC_PP1_RVXF_1	853	860	PF00149	0.474
DOC_PP2B_LxvP_1	1023	1026	PF13499	0.658
DOC_PP2B_LxvP_1	1028	1031	PF13499	0.674
DOC_PP2B_LxvP_1	116	119	PF13499	0.489
DOC_PP2B_LxvP_1	170	173	PF13499	0.512
DOC_PP2B_LxvP_1	882	885	PF13499	0.665
DOC_USP7_MATH_1	106	110	PF00917	0.683
DOC_USP7_MATH_1	111	115	PF00917	0.636
DOC_USP7_MATH_1	267	271	PF00917	0.657
DOC_USP7_MATH_1	322	326	PF00917	0.775
DOC_USP7_MATH_1	327	331	PF00917	0.691
DOC_USP7_MATH_1	479	483	PF00917	0.697
DOC_USP7_MATH_1	537	541	PF00917	0.765
DOC_USP7_MATH_1	733	737	PF00917	0.768
DOC_USP7_MATH_1	756	760	PF00917	0.673
DOC_USP7_MATH_1	761	765	PF00917	0.630
DOC_USP7_MATH_1	890	894	PF00917	0.781
DOC_USP7_MATH_1	967	971	PF00917	0.573
DOC_USP7_MATH_1	995	999	PF00917	0.611
DOC_USP7_MATH_2	936	942	PF00917	0.393
DOC_WW_Pin1_4	1068	1073	PF00397	0.335
DOC_WW_Pin1_4	1144	1149	PF00397	0.447
DOC_WW_Pin1_4	1254	1259	PF00397	0.567
DOC_WW_Pin1_4	263	268	PF00397	0.666
DOC_WW_Pin1_4	486	491	PF00397	0.708
DOC_WW_Pin1_4	5	10	PF00397	0.592
DOC_WW_Pin1_4	525	530	PF00397	0.714
DOC_WW_Pin1_4	754	759	PF00397	0.766
DOC_WW_Pin1_4	813	818	PF00397	0.670
DOC_WW_Pin1_4	845	850	PF00397	0.582
LIG_14-3-3_CanoR_1	1044	1048	PF00244	0.447
LIG_14-3-3_CanoR_1	1078	1085	PF00244	0.335
LIG_14-3-3_CanoR_1	16	25	PF00244	0.556
LIG_14-3-3_CanoR_1	268	272	PF00244	0.583
LIG_14-3-3_CanoR_1	362	372	PF00244	0.721
LIG_14-3-3_CanoR_1	384	392	PF00244	0.520
LIG_14-3-3_CanoR_1	443	452	PF00244	0.464
LIG_14-3-3_CanoR_1	480	484	PF00244	0.678
LIG_14-3-3_CanoR_1	519	525	PF00244	0.589
LIG_14-3-3_CanoR_1	536	546	PF00244	0.685
LIG_14-3-3_CanoR_1	605	611	PF00244	0.438
LIG_14-3-3_CanoR_1	651	657	PF00244	0.431
LIG_14-3-3_CanoR_1	732	738	PF00244	0.796
LIG_14-3-3_CanoR_1	84	93	PF00244	0.424
LIG_14-3-3_CanoR_1	907	911	PF00244	0.440
LIG_14-3-3_CanoR_1	939	947	PF00244	0.522
LIG_14-3-3_CanoR_1	990	996	PF00244	0.603
LIG_Actin_RPEL_3	151	170	PF02755	0.494
LIG_Actin_WH2_2	442	458	PF00022	0.412
LIG_Actin_WH2_2	600	618	PF00022	0.557
LIG_Actin_WH2_2	82	98	PF00022	0.566
LIG_Actin_WH2_2	975	992	PF00022	0.597
LIG_BIR_II_1	1	5	PF00653	0.740
LIG_BIR_III_2	755	759	PF00653	0.724
LIG_BIR_III_4	326	330	PF00653	0.557
LIG_BIR_III_4	712	716	PF00653	0.742
LIG_BRCT_BRCA1_1	41	45	PF00533	0.368
LIG_BRCT_BRCA1_1	418	422	PF00533	0.534
LIG_BRCT_BRCA1_1	497	501	PF00533	0.437
LIG_CaM_IQ_9	299	315	PF13499	0.403
LIG_Clathr_ClatBox_1	467	471	PF01394	0.399
LIG_Clathr_ClatBox_1	818	822	PF01394	0.537
LIG_FHA_1	1128	1134	PF00498	0.447
LIG_FHA_1	350	356	PF00498	0.746
LIG_FHA_1	413	419	PF00498	0.527
LIG_FHA_1	444	450	PF00498	0.454
LIG_FHA_1	463	469	PF00498	0.223
LIG_FHA_1	507	513	PF00498	0.464
LIG_FHA_1	6	12	PF00498	0.655
LIG_FHA_1	632	638	PF00498	0.501
LIG_FHA_1	640	646	PF00498	0.473
LIG_FHA_1	647	653	PF00498	0.355
LIG_FHA_1	678	684	PF00498	0.626
LIG_FHA_1	814	820	PF00498	0.649
LIG_FHA_1	868	874	PF00498	0.472
LIG_FHA_1	901	907	PF00498	0.732
LIG_FHA_1	940	946	PF00498	0.550
LIG_FHA_1	947	953	PF00498	0.494
LIG_FHA_1	977	983	PF00498	0.525
LIG_FHA_2	1062	1068	PF00498	0.389
LIG_FHA_2	1175	1181	PF00498	0.682
LIG_FHA_2	1191	1197	PF00498	0.626
LIG_FHA_2	15	21	PF00498	0.535
LIG_FHA_2	296	302	PF00498	0.483
LIG_FHA_2	346	352	PF00498	0.569
LIG_FHA_2	365	371	PF00498	0.622
LIG_FHA_2	398	404	PF00498	0.662
LIG_FHA_2	528	534	PF00498	0.673
LIG_FHA_2	596	602	PF00498	0.548
LIG_FHA_2	699	705	PF00498	0.774
LIG_FHA_2	716	722	PF00498	0.794
LIG_FHA_2	750	756	PF00498	0.773
LIG_LIR_Gen_1	1083	1093	PF02991	0.424
LIG_LIR_Gen_1	419	429	PF02991	0.545
LIG_LIR_Gen_1	462	470	PF02991	0.405
LIG_LIR_Gen_1	498	508	PF02991	0.482
LIG_LIR_Gen_1	657	667	PF02991	0.421
LIG_LIR_Gen_1	848	858	PF02991	0.579
LIG_LIR_Nem_3	1046	1052	PF02991	0.373
LIG_LIR_Nem_3	1083	1088	PF02991	0.424
LIG_LIR_Nem_3	1208	1213	PF02991	0.407
LIG_LIR_Nem_3	373	377	PF02991	0.726
LIG_LIR_Nem_3	419	425	PF02991	0.558
LIG_LIR_Nem_3	462	467	PF02991	0.404
LIG_LIR_Nem_3	498	504	PF02991	0.435
LIG_LIR_Nem_3	657	662	PF02991	0.437
LIG_LYPXL_yS_3	1137	1140	PF13949	0.447
LIG_MYND_1	1026	1030	PF01753	0.640
LIG_MYND_1	587	591	PF01753	0.577
LIG_NRBOX	286	292	PF00104	0.425
LIG_PCNA_yPIPBox_3	661	674	PF02747	0.539
LIG_Pex14_2	252	256	PF04695	0.515
LIG_SH2_CRK	1252	1256	PF00017	0.430
LIG_SH2_CRK	442	446	PF00017	0.508
LIG_SH2_CRK	464	468	PF00017	0.521
LIG_SH2_CRK	659	663	PF00017	0.533
LIG_SH2_CRK	69	73	PF00017	0.484
LIG_SH2_GRB2like	760	763	PF00017	0.592
LIG_SH2_SRC	1024	1027	PF00017	0.654
LIG_SH2_SRC	1104	1107	PF00017	0.408
LIG_SH2_SRC	760	763	PF00017	0.689
LIG_SH2_STAP1	1127	1131	PF00017	0.480
LIG_SH2_STAP1	1202	1206	PF00017	0.535
LIG_SH2_STAP1	464	468	PF00017	0.500
LIG_SH2_STAP1	648	652	PF00017	0.472
LIG_SH2_STAT5	1068	1071	PF00017	0.335
LIG_SH2_STAT5	1084	1087	PF00017	0.335
LIG_SH2_STAT5	391	394	PF00017	0.540
LIG_SH2_STAT5	464	467	PF00017	0.553
LIG_SH2_STAT5	648	651	PF00017	0.399
LIG_SH2_STAT5	69	72	PF00017	0.484
LIG_SH3_1	28	34	PF00018	0.613
LIG_SH3_3	1023	1029	PF00018	0.728
LIG_SH3_3	1066	1072	PF00018	0.335
LIG_SH3_3	115	121	PF00018	0.564
LIG_SH3_3	1166	1172	PF00018	0.440
LIG_SH3_3	273	279	PF00018	0.498
LIG_SH3_3	28	34	PF00018	0.613
LIG_SH3_3	68	74	PF00018	0.395
LIG_SH3_3	687	693	PF00018	0.611
LIG_SH3_3	805	811	PF00018	0.731
LIG_SH3_3	843	849	PF00018	0.556
LIG_SH3_CIN85_PxpxPR_1	1030	1035	PF14604	0.555
LIG_SUMO_SIM_anti_2	1237	1247	PF11976	0.553
LIG_SUMO_SIM_anti_2	542	554	PF11976	0.696
LIG_SUMO_SIM_anti_2	597	604	PF11976	0.521
LIG_SUMO_SIM_anti_2	634	639	PF11976	0.490
LIG_SUMO_SIM_anti_2	921	926	PF11976	0.481
LIG_SUMO_SIM_par_1	1059	1065	PF11976	0.321
LIG_SUMO_SIM_par_1	121	127	PF11976	0.549
LIG_SUMO_SIM_par_1	142	148	PF11976	0.378
LIG_SUMO_SIM_par_1	211	218	PF11976	0.479
LIG_SUMO_SIM_par_1	283	289	PF11976	0.507
LIG_SUMO_SIM_par_1	465	472	PF11976	0.508
LIG_SUMO_SIM_par_1	503	509	PF11976	0.524
LIG_SUMO_SIM_par_1	542	556	PF11976	0.696
LIG_SUMO_SIM_par_1	633	639	PF11976	0.479
LIG_SUMO_SIM_par_1	816	822	PF11976	0.539
LIG_SUMO_SIM_par_1	979	985	PF11976	0.641
LIG_TRAF2_1	124	127	PF00917	0.589
LIG_TRAF2_1	2	5	PF00917	0.664
LIG_TRAF2_1	298	301	PF00917	0.500
LIG_TRAF2_1	918	921	PF00917	0.565
LIG_TRFH_1	1068	1072	PF08558	0.335
LIG_UBA3_1	1154	1160	PF00899	0.411
LIG_UBA3_1	1228	1236	PF00899	0.347
MOD_CDC14_SPxK_1	266	269	PF00782	0.456
MOD_CDK_SPK_2	263	268	PF00069	0.546
MOD_CDK_SPxK_1	263	269	PF00069	0.582
MOD_CDK_SPxK_1	525	531	PF00069	0.558
MOD_CDK_SPxxK_3	845	852	PF00069	0.651
MOD_CK1_1	1087	1093	PF00069	0.319
MOD_CK1_1	1235	1241	PF00069	0.531
MOD_CK1_1	387	393	PF00069	0.658
MOD_CK1_1	410	416	PF00069	0.497
MOD_CK1_1	520	526	PF00069	0.676
MOD_CK1_1	527	533	PF00069	0.713
MOD_CK1_1	551	557	PF00069	0.722
MOD_CK1_1	764	770	PF00069	0.611
MOD_CK1_1	813	819	PF00069	0.650
MOD_CK1_1	862	868	PF00069	0.498
MOD_CK1_1	905	911	PF00069	0.640
MOD_CK2_1	1190	1196	PF00069	0.615
MOD_CK2_1	14	20	PF00069	0.543
MOD_CK2_1	23	29	PF00069	0.453
MOD_CK2_1	295	301	PF00069	0.509
MOD_CK2_1	469	475	PF00069	0.505
MOD_CK2_1	527	533	PF00069	0.708
MOD_CK2_1	536	542	PF00069	0.717
MOD_CK2_1	549	555	PF00069	0.678
MOD_CK2_1	595	601	PF00069	0.571
MOD_CK2_1	698	704	PF00069	0.763
MOD_CK2_1	708	714	PF00069	0.727
MOD_CK2_1	715	721	PF00069	0.767
MOD_CK2_1	84	90	PF00069	0.472
MOD_CK2_1	845	851	PF00069	0.746
MOD_CK2_1	862	868	PF00069	0.438
MOD_CK2_1	948	954	PF00069	0.515
MOD_GlcNHglycan	107	111	PF01048	0.702
MOD_GlcNHglycan	1079	1082	PF01048	0.349
MOD_GlcNHglycan	1089	1092	PF01048	0.321
MOD_GlcNHglycan	1123	1126	PF01048	0.412
MOD_GlcNHglycan	1182	1185	PF01048	0.664
MOD_GlcNHglycan	178	181	PF01048	0.671
MOD_GlcNHglycan	199	202	PF01048	0.649
MOD_GlcNHglycan	25	28	PF01048	0.473
MOD_GlcNHglycan	280	283	PF01048	0.484
MOD_GlcNHglycan	313	316	PF01048	0.636
MOD_GlcNHglycan	373	377	PF01048	0.732
MOD_GlcNHglycan	386	389	PF01048	0.739
MOD_GlcNHglycan	409	412	PF01048	0.547
MOD_GlcNHglycan	519	522	PF01048	0.678
MOD_GlcNHglycan	539	542	PF01048	0.756
MOD_GlcNHglycan	567	570	PF01048	0.753
MOD_GlcNHglycan	579	582	PF01048	0.658
MOD_GlcNHglycan	627	631	PF01048	0.630
MOD_GlcNHglycan	686	689	PF01048	0.702
MOD_GlcNHglycan	701	704	PF01048	0.656
MOD_GlcNHglycan	793	796	PF01048	0.733
MOD_GlcNHglycan	838	841	PF01048	0.660
MOD_GlcNHglycan	842	845	PF01048	0.687
MOD_GlcNHglycan	86	89	PF01048	0.447
MOD_GlcNHglycan	860	864	PF01048	0.411
MOD_GlcNHglycan	892	895	PF01048	0.764
MOD_GlcNHglycan	997	1000	PF01048	0.514
MOD_GSK3_1	1230	1237	PF00069	0.399
MOD_GSK3_1	172	179	PF00069	0.488
MOD_GSK3_1	263	270	PF00069	0.648
MOD_GSK3_1	327	334	PF00069	0.716
MOD_GSK3_1	345	352	PF00069	0.482
MOD_GSK3_1	379	386	PF00069	0.733
MOD_GSK3_1	412	419	PF00069	0.545
MOD_GSK3_1	479	486	PF00069	0.637
MOD_GSK3_1	520	527	PF00069	0.673
MOD_GSK3_1	532	539	PF00069	0.657
MOD_GSK3_1	547	554	PF00069	0.691
MOD_GSK3_1	563	570	PF00069	0.668
MOD_GSK3_1	577	584	PF00069	0.578
MOD_GSK3_1	606	613	PF00069	0.479
MOD_GSK3_1	646	653	PF00069	0.511
MOD_GSK3_1	694	701	PF00069	0.630
MOD_GSK3_1	80	87	PF00069	0.474
MOD_GSK3_1	836	843	PF00069	0.677
MOD_GSK3_1	890	897	PF00069	0.781
MOD_GSK3_1	902	909	PF00069	0.511
MOD_GSK3_1	967	974	PF00069	0.488
MOD_GSK3_1	985	992	PF00069	0.614
MOD_N-GLC_1	722	727	PF02516	0.615
MOD_N-GLC_1	761	766	PF02516	0.785
MOD_NEK2_1	1018	1023	PF00069	0.629
MOD_NEK2_1	1043	1048	PF00069	0.417
MOD_NEK2_1	1061	1066	PF00069	0.383
MOD_NEK2_1	11	16	PF00069	0.532
MOD_NEK2_1	1121	1126	PF00069	0.356
MOD_NEK2_1	1158	1163	PF00069	0.410
MOD_NEK2_1	1174	1179	PF00069	0.566
MOD_NEK2_1	1224	1229	PF00069	0.512
MOD_NEK2_1	176	181	PF00069	0.525
MOD_NEK2_1	197	202	PF00069	0.565
MOD_NEK2_1	222	227	PF00069	0.551
MOD_NEK2_1	311	316	PF00069	0.649
MOD_NEK2_1	363	368	PF00069	0.701
MOD_NEK2_1	372	377	PF00069	0.726
MOD_NEK2_1	445	450	PF00069	0.379
MOD_NEK2_1	606	611	PF00069	0.469
MOD_NEK2_1	636	641	PF00069	0.539
MOD_NEK2_1	859	864	PF00069	0.491
MOD_NEK2_1	873	878	PF00069	0.423
MOD_NEK2_1	947	952	PF00069	0.486
MOD_NEK2_1	971	976	PF00069	0.599
MOD_NEK2_1	978	983	PF00069	0.547
MOD_NEK2_2	479	484	PF00069	0.728
MOD_NEK2_2	733	738	PF00069	0.703
MOD_NEK2_2	902	907	PF00069	0.736
MOD_PIKK_1	397	403	PF00454	0.577
MOD_PIKK_1	740	746	PF00454	0.686
MOD_PIKK_1	764	770	PF00454	0.748
MOD_PIKK_1	782	788	PF00454	0.561
MOD_PKA_1	1010	1016	PF00069	0.713
MOD_PKA_1	739	745	PF00069	0.603
MOD_PKA_2	1043	1049	PF00069	0.447
MOD_PKA_2	1077	1083	PF00069	0.335
MOD_PKA_2	1196	1202	PF00069	0.638
MOD_PKA_2	267	273	PF00069	0.584
MOD_PKA_2	361	367	PF00069	0.679
MOD_PKA_2	383	389	PF00069	0.714
MOD_PKA_2	459	465	PF00069	0.493
MOD_PKA_2	479	485	PF00069	0.627
MOD_PKA_2	646	652	PF00069	0.388
MOD_PKA_2	739	745	PF00069	0.743
MOD_PKA_2	746	752	PF00069	0.757
MOD_PKA_2	890	896	PF00069	0.713
MOD_PKA_2	906	912	PF00069	0.340
MOD_PKA_2	938	944	PF00069	0.375
MOD_PKA_2	989	995	PF00069	0.566
MOD_PKB_1	738	746	PF00069	0.687
MOD_Plk_1	859	865	PF00069	0.523
MOD_Plk_1	867	873	PF00069	0.487
MOD_Plk_1	984	990	PF00069	0.608
MOD_Plk_2-3	469	475	PF00069	0.474
MOD_Plk_2-3	549	555	PF00069	0.742
MOD_Plk_2-3	595	601	PF00069	0.571
MOD_Plk_2-3	708	714	PF00069	0.749
MOD_Plk_2-3	716	722	PF00069	0.710
MOD_Plk_4	1018	1024	PF00069	0.714
MOD_Plk_4	1084	1090	PF00069	0.342
MOD_Plk_4	1224	1230	PF00069	0.499
MOD_Plk_4	1235	1241	PF00069	0.443
MOD_Plk_4	172	178	PF00069	0.508
MOD_Plk_4	280	286	PF00069	0.467
MOD_Plk_4	387	393	PF00069	0.652
MOD_Plk_4	445	451	PF00069	0.379
MOD_Plk_4	462	468	PF00069	0.407
MOD_Plk_4	469	475	PF00069	0.416
MOD_Plk_4	511	517	PF00069	0.485
MOD_Plk_4	631	637	PF00069	0.530
MOD_Plk_4	867	873	PF00069	0.457
MOD_Plk_4	978	984	PF00069	0.527
MOD_ProDKin_1	1068	1074	PF00069	0.335
MOD_ProDKin_1	1144	1150	PF00069	0.447
MOD_ProDKin_1	1254	1260	PF00069	0.582
MOD_ProDKin_1	263	269	PF00069	0.664
MOD_ProDKin_1	486	492	PF00069	0.697
MOD_ProDKin_1	5	11	PF00069	0.586
MOD_ProDKin_1	525	531	PF00069	0.718
MOD_ProDKin_1	754	760	PF00069	0.768
MOD_ProDKin_1	813	819	PF00069	0.645
MOD_ProDKin_1	845	851	PF00069	0.576
MOD_SUMO_rev_2	1071	1081	PF00179	0.335
MOD_SUMO_rev_2	2	8	PF00179	0.443
MOD_SUMO_rev_2	951	960	PF00179	0.555
TRG_DiLeu_BaEn_1	868	873	PF01217	0.516
TRG_DiLeu_BaEn_2	677	683	PF01217	0.442
TRG_DiLeu_BaLyEn_6	1169	1174	PF01217	0.523
TRG_DiLeu_BaLyEn_6	440	445	PF01217	0.522
TRG_DiLeu_BaLyEn_6	73	78	PF01217	0.564
TRG_DiLeu_BaLyEn_6	786	791	PF01217	0.741
TRG_DiLeu_BaLyEn_6	814	819	PF01217	0.684
TRG_ENDOCYTIC_2	1137	1140	PF00928	0.389
TRG_ENDOCYTIC_2	1252	1255	PF00928	0.429
TRG_ENDOCYTIC_2	442	445	PF00928	0.514
TRG_ENDOCYTIC_2	464	467	PF00928	0.518
TRG_ENDOCYTIC_2	659	662	PF00928	0.517
TRG_ENDOCYTIC_2	69	72	PF00928	0.484
TRG_ER_diArg_1	1004	1007	PF00400	0.663
TRG_ER_diArg_1	1052	1054	PF00400	0.392
TRG_ER_diArg_1	1138	1141	PF00400	0.402
TRG_ER_diArg_1	158	160	PF00400	0.409
TRG_ER_diArg_1	267	269	PF00400	0.647
TRG_ER_diArg_1	359	362	PF00400	0.640
TRG_ER_diArg_1	452	454	PF00400	0.398
TRG_ER_diArg_1	455	457	PF00400	0.397
TRG_ER_diArg_1	476	478	PF00400	0.608
TRG_ER_diArg_1	479	481	PF00400	0.671
TRG_ER_diArg_1	615	617	PF00400	0.495
TRG_ER_diArg_1	66	68	PF00400	0.546
TRG_ER_diArg_1	664	666	PF00400	0.493
TRG_ER_diArg_1	728	730	PF00400	0.651
TRG_ER_diArg_1	737	740	PF00400	0.795
TRG_NES_CRM1_1	301	312	PF08389	0.492
TRG_NES_CRM1_1	37	48	PF08389	0.370
TRG_NES_CRM1_1	920	934	PF08389	0.409
TRG_Pf-PMV_PEXEL_1	158	163	PF00026	0.449
TRG_Pf-PMV_PEXEL_1	224	228	PF00026	0.350
TRG_Pf-PMV_PEXEL_1	269	274	PF00026	0.439
TRG_Pf-PMV_PEXEL_1	443	447	PF00026	0.489
TRG_Pf-PMV_PEXEL_1	855	860	PF00026	0.514

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PGM4	Leptomonas seymouri	56%	92%
A0A1X0NQM0	Trypanosomatidae	35%	99%
A0A3S5H630	Leishmania donovani	99%	100%
A0A422NTR3	Trypanosoma rangeli	36%	100%
A4H581	Leishmania braziliensis	77%	100%
C9ZPP4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
E9AM93	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4QIF5	Leishmania major	90%	100%
V5BLN1	Trypanosoma cruzi	35%	100%