CST complex subunit CTC1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HTG4_LEIIN

TriTrypDb:

LINF_080006300

Length:

585

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HTG4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HTG4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	41	45	PF00656	0.537
CLV_C14_Caspase3-7	412	416	PF00656	0.531
CLV_NRD_NRD_1	186	188	PF00675	0.668
CLV_NRD_NRD_1	19	21	PF00675	0.515
CLV_NRD_NRD_1	256	258	PF00675	0.570
CLV_NRD_NRD_1	364	366	PF00675	0.426
CLV_NRD_NRD_1	536	538	PF00675	0.465
CLV_PCSK_FUR_1	253	257	PF00082	0.586
CLV_PCSK_KEX2_1	186	188	PF00082	0.668
CLV_PCSK_KEX2_1	19	21	PF00082	0.515
CLV_PCSK_KEX2_1	255	257	PF00082	0.572
CLV_PCSK_KEX2_1	364	366	PF00082	0.426
CLV_PCSK_KEX2_1	536	538	PF00082	0.470
CLV_PCSK_KEX2_1	549	551	PF00082	0.443
CLV_PCSK_PC1ET2_1	549	551	PF00082	0.443
CLV_PCSK_PC7_1	251	257	PF00082	0.590
CLV_PCSK_PC7_1	360	366	PF00082	0.397
CLV_PCSK_SKI1_1	145	149	PF00082	0.445
CLV_PCSK_SKI1_1	202	206	PF00082	0.543
CLV_PCSK_SKI1_1	331	335	PF00082	0.587
CLV_PCSK_SKI1_1	398	402	PF00082	0.578
DEG_APCC_DBOX_1	330	338	PF00400	0.559
DEG_Nend_Nbox_1	1	3	PF02207	0.535
DEG_SCF_FBW7_1	292	299	PF00400	0.628
DEG_SPOP_SBC_1	21	25	PF00917	0.490
DEG_SPOP_SBC_1	222	226	PF00917	0.611
DOC_AGCK_PIF_2	571	576	PF00069	0.341
DOC_ANK_TNKS_1	388	395	PF00023	0.385
DOC_CDC14_PxL_1	483	491	PF14671	0.518
DOC_CKS1_1	93	98	PF01111	0.491
DOC_CYCLIN_yCln2_LP_2	348	354	PF00134	0.705
DOC_CYCLIN_yCln2_LP_2	93	99	PF00134	0.461
DOC_MAPK_FxFP_2	168	171	PF00069	0.527
DOC_MAPK_gen_1	255	264	PF00069	0.609
DOC_MAPK_MEF2A_6	438	445	PF00069	0.394
DOC_PP1_RVXF_1	529	536	PF00149	0.495
DOC_PP2B_LxvP_1	148	151	PF13499	0.451
DOC_PP2B_LxvP_1	340	343	PF13499	0.513
DOC_PP2B_PxIxI_1	472	478	PF00149	0.379
DOC_PP4_FxxP_1	168	171	PF00568	0.527
DOC_PP4_FxxP_1	494	497	PF00568	0.414
DOC_PP4_FxxP_1	529	532	PF00568	0.454
DOC_USP7_MATH_1	21	25	PF00917	0.609
DOC_USP7_MATH_1	266	270	PF00917	0.627
DOC_USP7_MATH_1	296	300	PF00917	0.605
DOC_USP7_MATH_1	61	65	PF00917	0.663
DOC_USP7_UBL2_3	555	559	PF12436	0.472
DOC_WW_Pin1_4	162	167	PF00397	0.564
DOC_WW_Pin1_4	239	244	PF00397	0.629
DOC_WW_Pin1_4	292	297	PF00397	0.620
DOC_WW_Pin1_4	317	322	PF00397	0.739
DOC_WW_Pin1_4	92	97	PF00397	0.453
LIG_14-3-3_CanoR_1	100	108	PF00244	0.732
LIG_14-3-3_CanoR_1	19	26	PF00244	0.528
LIG_14-3-3_CanoR_1	531	536	PF00244	0.345
LIG_14-3-3_CanoR_1	62	71	PF00244	0.582
LIG_APCC_ABBAyCdc20_2	398	404	PF00400	0.480
LIG_BIR_III_4	391	395	PF00653	0.442
LIG_BIR_III_4	415	419	PF00653	0.556
LIG_BRCT_BRCA1_1	119	123	PF00533	0.575
LIG_BRCT_BRCA1_1	164	168	PF00533	0.515
LIG_Clathr_ClatBox_1	474	478	PF01394	0.337
LIG_DLG_GKlike_1	531	538	PF00625	0.331
LIG_FHA_1	100	106	PF00498	0.610
LIG_FHA_1	175	181	PF00498	0.573
LIG_FHA_1	223	229	PF00498	0.616
LIG_FHA_1	343	349	PF00498	0.624
LIG_FHA_1	357	363	PF00498	0.423
LIG_FHA_1	383	389	PF00498	0.504
LIG_FHA_1	509	515	PF00498	0.419
LIG_FHA_2	334	340	PF00498	0.552
LIG_FHA_2	434	440	PF00498	0.432
LIG_LIR_Apic_2	165	171	PF02991	0.517
LIG_LIR_Apic_2	527	532	PF02991	0.460
LIG_LIR_Gen_1	570	579	PF02991	0.390
LIG_LIR_Nem_3	120	126	PF02991	0.540
LIG_LIR_Nem_3	141	147	PF02991	0.547
LIG_LIR_Nem_3	269	273	PF02991	0.544
LIG_LIR_Nem_3	305	309	PF02991	0.620
LIG_LIR_Nem_3	501	506	PF02991	0.421
LIG_LIR_Nem_3	525	529	PF02991	0.474
LIG_LIR_Nem_3	534	538	PF02991	0.344
LIG_LIR_Nem_3	570	574	PF02991	0.379
LIG_LIR_Nem_3	575	579	PF02991	0.397
LIG_LIR_Nem_3	87	93	PF02991	0.501
LIG_Pex14_2	522	526	PF04695	0.400
LIG_REV1ctd_RIR_1	202	211	PF16727	0.483
LIG_RPA_C_Fungi	15	27	PF08784	0.506
LIG_RPA_C_Fungi	57	69	PF08784	0.572
LIG_SH2_CRK	144	148	PF00017	0.554
LIG_SH2_CRK	285	289	PF00017	0.607
LIG_SH2_GRB2like	108	111	PF00017	0.530
LIG_SH2_PTP2	576	579	PF00017	0.374
LIG_SH2_SRC	108	111	PF00017	0.530
LIG_SH2_STAP1	386	390	PF00017	0.362
LIG_SH2_STAT3	149	152	PF00017	0.554
LIG_SH2_STAT5	108	111	PF00017	0.490
LIG_SH2_STAT5	158	161	PF00017	0.676
LIG_SH2_STAT5	386	389	PF00017	0.350
LIG_SH2_STAT5	576	579	PF00017	0.334
LIG_SH2_STAT5	92	95	PF00017	0.639
LIG_SH3_1	285	291	PF00018	0.630
LIG_SH3_2	351	356	PF14604	0.442
LIG_SH3_3	144	150	PF00018	0.689
LIG_SH3_3	213	219	PF00018	0.586
LIG_SH3_3	244	250	PF00018	0.630
LIG_SH3_3	262	268	PF00018	0.483
LIG_SH3_3	273	279	PF00018	0.536
LIG_SH3_3	285	291	PF00018	0.562
LIG_SH3_3	295	301	PF00018	0.545
LIG_SH3_3	348	354	PF00018	0.513
LIG_SH3_3	442	448	PF00018	0.530
LIG_SH3_3	490	496	PF00018	0.446
LIG_SH3_3	50	56	PF00018	0.585
LIG_SH3_3	93	99	PF00018	0.477
LIG_SH3_CIN85_PxpxPR_1	284	289	PF14604	0.624
LIG_SUMO_SIM_anti_2	272	278	PF11976	0.547
LIG_SUMO_SIM_par_1	344	350	PF11976	0.575
LIG_SUMO_SIM_par_1	376	381	PF11976	0.443
LIG_SUMO_SIM_par_1	473	478	PF11976	0.349
LIG_TRAF2_1	291	294	PF00917	0.632
LIG_TRAF2_1	561	564	PF00917	0.422
LIG_UBA3_1	273	282	PF00899	0.552
MOD_CK1_1	136	142	PF00069	0.531
MOD_CK1_1	22	28	PF00069	0.487
MOD_CK1_1	4	10	PF00069	0.508
MOD_CK1_1	64	70	PF00069	0.617
MOD_CK2_1	266	272	PF00069	0.694
MOD_CK2_1	333	339	PF00069	0.557
MOD_GlcNHglycan	135	138	PF01048	0.619
MOD_GlcNHglycan	229	232	PF01048	0.604
MOD_GlcNHglycan	236	239	PF01048	0.632
MOD_GlcNHglycan	3	6	PF01048	0.484
MOD_GlcNHglycan	309	312	PF01048	0.689
MOD_GlcNHglycan	429	433	PF01048	0.506
MOD_GlcNHglycan	550	553	PF01048	0.443
MOD_GlcNHglycan	64	67	PF01048	0.611
MOD_GSK3_1	176	183	PF00069	0.704
MOD_GSK3_1	217	224	PF00069	0.576
MOD_GSK3_1	234	241	PF00069	0.605
MOD_GSK3_1	245	252	PF00069	0.641
MOD_GSK3_1	292	299	PF00069	0.775
MOD_GSK3_1	378	385	PF00069	0.470
MOD_GSK3_1	508	515	PF00069	0.447
MOD_LATS_1	18	24	PF00433	0.507
MOD_NEK2_1	1	6	PF00069	0.501
MOD_NEK2_1	234	239	PF00069	0.748
MOD_NEK2_1	245	250	PF00069	0.647
MOD_NEK2_1	333	338	PF00069	0.569
MOD_NEK2_1	382	387	PF00069	0.420
MOD_NEK2_1	506	511	PF00069	0.406
MOD_PIKK_1	99	105	PF00454	0.552
MOD_PKA_1	19	25	PF00069	0.466
MOD_PKA_1	256	262	PF00069	0.575
MOD_PKA_2	117	123	PF00069	0.502
MOD_PKA_2	127	133	PF00069	0.575
MOD_PKA_2	19	25	PF00069	0.505
MOD_PKA_2	217	223	PF00069	0.580
MOD_PKA_2	256	262	PF00069	0.723
MOD_PKA_2	61	67	PF00069	0.623
MOD_PKA_2	99	105	PF00069	0.719
MOD_PKB_1	187	195	PF00069	0.559
MOD_PKB_1	249	257	PF00069	0.592
MOD_Plk_1	382	388	PF00069	0.373
MOD_Plk_2-3	433	439	PF00069	0.427
MOD_Plk_4	223	229	PF00069	0.603
MOD_Plk_4	272	278	PF00069	0.552
MOD_Plk_4	373	379	PF00069	0.385
MOD_Plk_4	498	504	PF00069	0.411
MOD_ProDKin_1	162	168	PF00069	0.563
MOD_ProDKin_1	239	245	PF00069	0.630
MOD_ProDKin_1	292	298	PF00069	0.618
MOD_ProDKin_1	317	323	PF00069	0.742
MOD_ProDKin_1	92	98	PF00069	0.452
TRG_DiLeu_BaEn_1	329	334	PF01217	0.530
TRG_DiLeu_BaEn_4	564	570	PF01217	0.379
TRG_DiLeu_BaLyEn_6	470	475	PF01217	0.402
TRG_ENDOCYTIC_2	108	111	PF00928	0.530
TRG_ENDOCYTIC_2	144	147	PF00928	0.509
TRG_ENDOCYTIC_2	576	579	PF00928	0.334
TRG_ER_diArg_1	185	187	PF00400	0.674
TRG_ER_diArg_1	250	253	PF00400	0.569
TRG_ER_diArg_1	255	257	PF00400	0.557
TRG_ER_diArg_1	364	366	PF00400	0.426
TRG_ER_diArg_1	419	422	PF00400	0.611
TRG_ER_diArg_1	535	537	PF00400	0.491
TRG_Pf-PMV_PEXEL_1	536	540	PF00026	0.396

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I943	Leptomonas seymouri	49%	97%
A0A3S5H629	Leishmania donovani	99%	100%
E9AM92	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%