LeishMANIAdb
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Putative vacuolar-type Ca2+-ATPase

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative vacuolar-type Ca2+-ATPase
Gene product:
vacuolar-type Ca2+-ATPase - putative
Species:
Leishmania infantum
UniProt:
A4HTF0_LEIIN
TriTrypDb:
LINF_070011900 *
Length:
929

Annotations

LeishMANIAdb annotations

Homologous to other eukaryotic P-type Ca2+ ATPases.. For some reason, this group has heavily expanded in Kinetoplastida.. Localization: Endosomal (by homology) / ER (by homology)

Annotations by Jardim et al.

Acidocalcisome, vacuolar-type Ca2+-ATPase (Fragment)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 16
NetGPI no yes: 0, no: 16
Cellular components
Term Name Level Count
GO:0016020 membrane 2 17
GO:0110165 cellular anatomical entity 1 17
GO:0005886 plasma membrane 3 2
GO:0043226 organelle 2 2
GO:0043227 membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043231 intracellular membrane-bounded organelle 4 2

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

A4HTF0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HTF0

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 17
GO:0003824 catalytic activity 1 17
GO:0005488 binding 1 17
GO:0005524 ATP binding 5 17
GO:0016462 pyrophosphatase activity 5 17
GO:0016787 hydrolase activity 2 17
GO:0016817 hydrolase activity, acting on acid anhydrides 3 17
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 17
GO:0016887 ATP hydrolysis activity 7 17
GO:0017076 purine nucleotide binding 4 17
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 17
GO:0030554 adenyl nucleotide binding 5 17
GO:0032553 ribonucleotide binding 3 17
GO:0032555 purine ribonucleotide binding 4 17
GO:0032559 adenyl ribonucleotide binding 5 17
GO:0035639 purine ribonucleoside triphosphate binding 4 17
GO:0036094 small molecule binding 2 17
GO:0043167 ion binding 2 17
GO:0043168 anion binding 3 17
GO:0097159 organic cyclic compound binding 2 17
GO:0097367 carbohydrate derivative binding 2 17
GO:1901265 nucleoside phosphate binding 3 17
GO:1901363 heterocyclic compound binding 2 17
GO:0005215 transporter activity 1 13
GO:0005388 P-type calcium transporter activity 4 13
GO:0008324 monoatomic cation transmembrane transporter activity 4 13
GO:0015075 monoatomic ion transmembrane transporter activity 3 13
GO:0015085 calcium ion transmembrane transporter activity 6 13
GO:0015318 inorganic molecular entity transmembrane transporter activity 3 13
GO:0015399 primary active transmembrane transporter activity 4 13
GO:0015662 P-type ion transporter activity 4 13
GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3 13
GO:0022804 active transmembrane transporter activity 3 13
GO:0022853 active monoatomic ion transmembrane transporter activity 4 13
GO:0022857 transmembrane transporter activity 2 13
GO:0022890 inorganic cation transmembrane transporter activity 4 13
GO:0042626 ATPase-coupled transmembrane transporter activity 2 13
GO:0046873 metal ion transmembrane transporter activity 5 13
GO:0140358 P-type transmembrane transporter activity 3 13
GO:0140657 ATP-dependent activity 1 13

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 505 509 PF00656 0.495
CLV_C14_Caspase3-7 639 643 PF00656 0.545
CLV_NRD_NRD_1 18 20 PF00675 0.540
CLV_NRD_NRD_1 196 198 PF00675 0.334
CLV_NRD_NRD_1 389 391 PF00675 0.363
CLV_NRD_NRD_1 537 539 PF00675 0.257
CLV_NRD_NRD_1 797 799 PF00675 0.285
CLV_NRD_NRD_1 865 867 PF00675 0.242
CLV_NRD_NRD_1 873 875 PF00675 0.212
CLV_NRD_NRD_1 92 94 PF00675 0.235
CLV_PCSK_FUR_1 194 198 PF00082 0.325
CLV_PCSK_KEX2_1 179 181 PF00082 0.467
CLV_PCSK_KEX2_1 18 20 PF00082 0.453
CLV_PCSK_KEX2_1 196 198 PF00082 0.315
CLV_PCSK_KEX2_1 389 391 PF00082 0.363
CLV_PCSK_KEX2_1 431 433 PF00082 0.449
CLV_PCSK_KEX2_1 539 541 PF00082 0.280
CLV_PCSK_KEX2_1 860 862 PF00082 0.292
CLV_PCSK_KEX2_1 873 875 PF00082 0.183
CLV_PCSK_KEX2_1 92 94 PF00082 0.241
CLV_PCSK_PC1ET2_1 179 181 PF00082 0.406
CLV_PCSK_PC1ET2_1 431 433 PF00082 0.452
CLV_PCSK_PC1ET2_1 539 541 PF00082 0.282
CLV_PCSK_PC1ET2_1 860 862 PF00082 0.295
CLV_PCSK_SKI1_1 123 127 PF00082 0.354
CLV_PCSK_SKI1_1 200 204 PF00082 0.347
CLV_PCSK_SKI1_1 345 349 PF00082 0.246
CLV_PCSK_SKI1_1 527 531 PF00082 0.330
CLV_PCSK_SKI1_1 702 706 PF00082 0.398
CLV_PCSK_SKI1_1 724 728 PF00082 0.279
CLV_PCSK_SKI1_1 798 802 PF00082 0.274
CLV_PCSK_SKI1_1 92 96 PF00082 0.282
CLV_PCSK_SKI1_1 98 102 PF00082 0.264
DEG_MDM2_SWIB_1 896 903 PF02201 0.377
DEG_SCF_FBW7_2 296 303 PF00400 0.467
DEG_SPOP_SBC_1 466 470 PF00917 0.635
DOC_CYCLIN_RxL_1 796 806 PF00134 0.482
DOC_CYCLIN_yCln2_LP_2 436 442 PF00134 0.649
DOC_MAPK_DCC_7 432 442 PF00069 0.645
DOC_MAPK_gen_1 194 204 PF00069 0.522
DOC_MAPK_gen_1 798 805 PF00069 0.484
DOC_MAPK_gen_1 873 881 PF00069 0.475
DOC_MAPK_gen_1 905 915 PF00069 0.308
DOC_MAPK_MEF2A_6 197 206 PF00069 0.495
DOC_MAPK_MEF2A_6 724 731 PF00069 0.498
DOC_MAPK_MEF2A_6 798 807 PF00069 0.454
DOC_MAPK_MEF2A_6 873 881 PF00069 0.435
DOC_MAPK_NFAT4_5 724 732 PF00069 0.499
DOC_MAPK_NFAT4_5 798 806 PF00069 0.454
DOC_PP1_RVXF_1 783 790 PF00149 0.470
DOC_PP2B_LxvP_1 137 140 PF13499 0.412
DOC_PP2B_LxvP_1 221 224 PF13499 0.451
DOC_USP7_MATH_1 129 133 PF00917 0.309
DOC_USP7_MATH_1 458 462 PF00917 0.582
DOC_USP7_MATH_1 533 537 PF00917 0.433
DOC_USP7_MATH_1 620 624 PF00917 0.590
DOC_USP7_MATH_1 767 771 PF00917 0.510
DOC_USP7_MATH_1 869 873 PF00917 0.467
DOC_USP7_UBL2_3 179 183 PF12436 0.655
DOC_WW_Pin1_4 215 220 PF00397 0.499
DOC_WW_Pin1_4 296 301 PF00397 0.430
DOC_WW_Pin1_4 32 37 PF00397 0.579
DOC_WW_Pin1_4 57 62 PF00397 0.493
DOC_WW_Pin1_4 824 829 PF00397 0.297
LIG_14-3-3_CanoR_1 123 128 PF00244 0.301
LIG_14-3-3_CanoR_1 446 451 PF00244 0.587
LIG_Actin_WH2_2 65 83 PF00022 0.521
LIG_AP2alpha_1 347 351 PF02296 0.467
LIG_BIR_II_1 1 5 PF00653 0.614
LIG_BIR_III_4 695 699 PF00653 0.617
LIG_DLG_GKlike_1 446 453 PF00625 0.577
LIG_EVH1_2 105 109 PF00568 0.525
LIG_FHA_1 149 155 PF00498 0.253
LIG_FHA_1 201 207 PF00498 0.446
LIG_FHA_1 258 264 PF00498 0.467
LIG_FHA_1 369 375 PF00498 0.485
LIG_FHA_1 406 412 PF00498 0.491
LIG_FHA_1 5 11 PF00498 0.628
LIG_FHA_1 600 606 PF00498 0.510
LIG_FHA_1 619 625 PF00498 0.373
LIG_FHA_1 829 835 PF00498 0.263
LIG_FHA_1 876 882 PF00498 0.486
LIG_FHA_2 106 112 PF00498 0.495
LIG_FHA_2 136 142 PF00498 0.429
LIG_FHA_2 264 270 PF00498 0.461
LIG_FHA_2 33 39 PF00498 0.605
LIG_FHA_2 468 474 PF00498 0.649
LIG_FHA_2 503 509 PF00498 0.535
LIG_FHA_2 683 689 PF00498 0.505
LIG_FHA_2 731 737 PF00498 0.579
LIG_GBD_Chelix_1 72 80 PF00786 0.245
LIG_Integrin_RGD_1 679 681 PF01839 0.291
LIG_LIR_Gen_1 155 165 PF02991 0.328
LIG_LIR_Gen_1 178 187 PF02991 0.661
LIG_LIR_Gen_1 60 69 PF02991 0.579
LIG_LIR_Gen_1 623 632 PF02991 0.539
LIG_LIR_Gen_1 806 817 PF02991 0.344
LIG_LIR_Gen_1 912 922 PF02991 0.284
LIG_LIR_LC3C_4 218 223 PF02991 0.485
LIG_LIR_Nem_3 108 113 PF02991 0.433
LIG_LIR_Nem_3 155 160 PF02991 0.328
LIG_LIR_Nem_3 178 184 PF02991 0.571
LIG_LIR_Nem_3 331 336 PF02991 0.449
LIG_LIR_Nem_3 349 353 PF02991 0.422
LIG_LIR_Nem_3 60 66 PF02991 0.583
LIG_LIR_Nem_3 623 629 PF02991 0.543
LIG_LIR_Nem_3 688 692 PF02991 0.519
LIG_LIR_Nem_3 777 783 PF02991 0.459
LIG_LIR_Nem_3 806 812 PF02991 0.344
LIG_LIR_Nem_3 912 918 PF02991 0.284
LIG_NRBOX 322 328 PF00104 0.482
LIG_PCNA_TLS_4 345 352 PF02747 0.478
LIG_PCNA_yPIPBox_3 791 801 PF02747 0.460
LIG_Pex14_1 153 157 PF04695 0.328
LIG_Pex14_2 347 351 PF04695 0.467
LIG_Pex14_2 896 900 PF04695 0.323
LIG_PTB_Apo_2 688 695 PF02174 0.576
LIG_PTB_Apo_2 752 759 PF02174 0.504
LIG_PTB_Phospho_1 688 694 PF10480 0.573
LIG_REV1ctd_RIR_1 93 101 PF16727 0.525
LIG_SH2_CRK 607 611 PF00017 0.594
LIG_SH2_GRB2like 570 573 PF00017 0.599
LIG_SH2_PTP2 809 812 PF00017 0.427
LIG_SH2_STAT5 229 232 PF00017 0.451
LIG_SH2_STAT5 350 353 PF00017 0.476
LIG_SH2_STAT5 422 425 PF00017 0.490
LIG_SH2_STAT5 570 573 PF00017 0.551
LIG_SH2_STAT5 809 812 PF00017 0.426
LIG_SH3_3 136 142 PF00018 0.447
LIG_SH3_3 23 29 PF00018 0.708
LIG_SH3_3 357 363 PF00018 0.433
LIG_SH3_3 427 433 PF00018 0.546
LIG_SH3_3 632 638 PF00018 0.550
LIG_SH3_3 99 105 PF00018 0.525
LIG_SUMO_SIM_anti_2 162 168 PF11976 0.294
LIG_SUMO_SIM_anti_2 772 778 PF11976 0.481
LIG_SUMO_SIM_anti_2 878 883 PF11976 0.395
LIG_SUMO_SIM_par_1 162 168 PF11976 0.294
LIG_SUMO_SIM_par_1 201 208 PF11976 0.442
LIG_SUMO_SIM_par_1 255 260 PF11976 0.461
LIG_SUMO_SIM_par_1 325 331 PF11976 0.466
LIG_SUMO_SIM_par_1 358 364 PF11976 0.436
LIG_SUMO_SIM_par_1 366 371 PF11976 0.438
LIG_SUMO_SIM_par_1 727 733 PF11976 0.517
LIG_SUMO_SIM_par_1 736 741 PF11976 0.446
LIG_SUMO_SIM_par_1 772 778 PF11976 0.471
LIG_TRAF2_1 300 303 PF00917 0.460
LIG_TRAF2_1 850 853 PF00917 0.353
LIG_TRAF2_1 854 857 PF00917 0.482
LIG_TYR_ITIM 348 353 PF00017 0.482
LIG_TYR_ITIM 605 610 PF00017 0.528
LIG_TYR_ITIM 807 812 PF00017 0.427
MOD_CDK_SPxxK_3 32 39 PF00069 0.504
MOD_CK1_1 240 246 PF00069 0.447
MOD_CK1_1 340 346 PF00069 0.524
MOD_CK1_1 405 411 PF00069 0.507
MOD_CK1_1 827 833 PF00069 0.270
MOD_CK2_1 105 111 PF00069 0.521
MOD_CK2_1 32 38 PF00069 0.637
MOD_CK2_1 325 331 PF00069 0.454
MOD_CK2_1 458 464 PF00069 0.536
MOD_CK2_1 467 473 PF00069 0.588
MOD_CK2_1 730 736 PF00069 0.579
MOD_GlcNHglycan 186 191 PF01048 0.408
MOD_GlcNHglycan 339 342 PF01048 0.195
MOD_GlcNHglycan 442 445 PF01048 0.422
MOD_GlcNHglycan 541 544 PF01048 0.276
MOD_GlcNHglycan 761 764 PF01048 0.322
MOD_GlcNHglycan 769 772 PF01048 0.299
MOD_GSK3_1 113 120 PF00069 0.534
MOD_GSK3_1 164 171 PF00069 0.286
MOD_GSK3_1 182 189 PF00069 0.572
MOD_GSK3_1 200 207 PF00069 0.388
MOD_GSK3_1 259 266 PF00069 0.454
MOD_GSK3_1 398 405 PF00069 0.479
MOD_GSK3_1 72 79 PF00069 0.525
MOD_GSK3_1 738 745 PF00069 0.489
MOD_GSK3_1 808 815 PF00069 0.312
MOD_GSK3_1 823 830 PF00069 0.286
MOD_GSK3_1 848 855 PF00069 0.284
MOD_GSK3_1 904 911 PF00069 0.318
MOD_LATS_1 555 561 PF00433 0.467
MOD_N-GLC_1 215 220 PF02516 0.339
MOD_N-GLC_1 398 403 PF02516 0.319
MOD_N-GLC_1 4 9 PF02516 0.400
MOD_N-GLC_1 459 464 PF02516 0.315
MOD_N-GLC_1 488 493 PF02516 0.233
MOD_N-GLC_1 599 604 PF02516 0.299
MOD_N-GLC_1 675 680 PF02516 0.315
MOD_NEK2_1 135 140 PF00069 0.304
MOD_NEK2_1 228 233 PF00069 0.524
MOD_NEK2_1 259 264 PF00069 0.435
MOD_NEK2_1 287 292 PF00069 0.467
MOD_NEK2_1 368 373 PF00069 0.466
MOD_NEK2_1 374 379 PF00069 0.433
MOD_NEK2_1 445 450 PF00069 0.586
MOD_NEK2_1 675 680 PF00069 0.585
MOD_NEK2_1 682 687 PF00069 0.552
MOD_NEK2_1 716 721 PF00069 0.502
MOD_NEK2_1 730 735 PF00069 0.497
MOD_NEK2_1 76 81 PF00069 0.502
MOD_NEK2_1 803 808 PF00069 0.289
MOD_NEK2_1 816 821 PF00069 0.297
MOD_NEK2_1 875 880 PF00069 0.445
MOD_NEK2_2 650 655 PF00069 0.490
MOD_PIKK_1 374 380 PF00454 0.454
MOD_PIKK_1 398 404 PF00454 0.500
MOD_PIKK_1 409 415 PF00454 0.515
MOD_PIKK_1 716 722 PF00454 0.517
MOD_PKA_1 539 545 PF00069 0.482
MOD_PKA_2 445 451 PF00069 0.508
MOD_PKA_2 539 545 PF00069 0.525
MOD_PKA_2 904 910 PF00069 0.235
MOD_PKB_1 525 533 PF00069 0.501
MOD_Plk_1 117 123 PF00069 0.505
MOD_Plk_1 200 206 PF00069 0.475
MOD_Plk_1 237 243 PF00069 0.442
MOD_Plk_1 278 284 PF00069 0.467
MOD_Plk_1 398 404 PF00069 0.512
MOD_Plk_1 599 605 PF00069 0.492
MOD_Plk_1 908 914 PF00069 0.295
MOD_Plk_2-3 85 91 PF00069 0.514
MOD_Plk_2-3 852 858 PF00069 0.482
MOD_Plk_4 105 111 PF00069 0.440
MOD_Plk_4 117 123 PF00069 0.440
MOD_Plk_4 129 135 PF00069 0.268
MOD_Plk_4 159 165 PF00069 0.297
MOD_Plk_4 231 237 PF00069 0.455
MOD_Plk_4 259 265 PF00069 0.454
MOD_Plk_4 325 331 PF00069 0.472
MOD_Plk_4 414 420 PF00069 0.494
MOD_Plk_4 548 554 PF00069 0.511
MOD_Plk_4 620 626 PF00069 0.578
MOD_Plk_4 711 717 PF00069 0.571
MOD_Plk_4 812 818 PF00069 0.310
MOD_Plk_4 909 915 PF00069 0.229
MOD_ProDKin_1 215 221 PF00069 0.499
MOD_ProDKin_1 296 302 PF00069 0.430
MOD_ProDKin_1 32 38 PF00069 0.574
MOD_ProDKin_1 57 63 PF00069 0.485
MOD_ProDKin_1 824 830 PF00069 0.234
MOD_SUMO_rev_2 536 541 PF00179 0.450
TRG_DiLeu_BaEn_1 307 312 PF01217 0.501
TRG_DiLeu_BaEn_1 548 553 PF01217 0.535
TRG_DiLeu_BaLyEn_6 120 125 PF01217 0.413
TRG_ENDOCYTIC_2 350 353 PF00928 0.470
TRG_ENDOCYTIC_2 422 425 PF00928 0.490
TRG_ENDOCYTIC_2 607 610 PF00928 0.509
TRG_ENDOCYTIC_2 63 66 PF00928 0.554
TRG_ENDOCYTIC_2 809 812 PF00928 0.452
TRG_ENDOCYTIC_2 898 901 PF00928 0.252
TRG_ER_diArg_1 18 20 PF00400 0.682
TRG_ER_diArg_1 193 196 PF00400 0.539
TRG_ER_diArg_1 388 390 PF00400 0.551
TRG_ER_diArg_1 538 541 PF00400 0.524
TRG_ER_diArg_1 585 588 PF00400 0.592
TRG_ER_diArg_1 873 875 PF00400 0.434
TRG_NES_CRM1_1 622 634 PF08389 0.555
TRG_NES_CRM1_1 720 736 PF08389 0.522
TRG_NLS_MonoExtN_4 248 253 PF00514 0.482
TRG_Pf-PMV_PEXEL_1 285 289 PF00026 0.267
TRG_Pf-PMV_PEXEL_1 334 339 PF00026 0.293
TRG_Pf-PMV_PEXEL_1 451 455 PF00026 0.359
TRG_Pf-PMV_PEXEL_1 690 695 PF00026 0.349

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3Y1 Leptomonas seymouri 30% 92%
A0A0N1HWG6 Leptomonas seymouri 41% 83%
A0A0N1I8I8 Leptomonas seymouri 33% 76%
A0A0N1PFH3 Leptomonas seymouri 28% 76%
A0A0S4J1M1 Bodo saltans 27% 85%
A0A0S4J5A1 Bodo saltans 29% 87%
A0A0S4J6U4 Bodo saltans 39% 85%
A0A0S4JA92 Bodo saltans 44% 92%
A0A0S4JRV4 Bodo saltans 43% 92%
A0A0S4KIG5 Bodo saltans 29% 92%
A0A0S4KNQ6 Bodo saltans 66% 83%
A0A1X0NNY6 Trypanosomatidae 28% 92%
A0A1X0NPD9 Trypanosomatidae 71% 84%
A0A1X0NTI6 Trypanosomatidae 41% 82%
A0A1X0P0Y8 Trypanosomatidae 36% 85%
A0A1X0P689 Trypanosomatidae 28% 89%
A0A381MFJ0 Leishmania infantum 24% 100%
A0A3R7KM63 Trypanosoma rangeli 70% 89%
A0A3R7MRX8 Trypanosoma rangeli 29% 89%
A0A3S5H5Y9 Leishmania donovani 100% 84%
A0A3S5ISK9 Trypanosoma rangeli 36% 87%
A0A3S7WPW0 Leishmania donovani 96% 83%
A0A3S7WUG2 Leishmania donovani 40% 82%
A0A3S7WV61 Leishmania donovani 24% 95%
A0A3S7WV68 Leishmania donovani 24% 95%
A0A3S7X6H3 Leishmania donovani 31% 78%
A0A3S7X978 Leishmania donovani 27% 84%
A0A422NTS7 Trypanosoma rangeli 29% 92%
A0A451EJU6 Leishmania donovani 28% 91%
A0RA13 Bacillus thuringiensis (strain Al Hakam) 25% 100%
A2VDL6 Bos taurus 28% 91%
A4H3S2 Leishmania braziliensis 27% 100%
A4H514 Leishmania braziliensis 91% 100%
A4H903 Leishmania braziliensis 41% 100%
A4H9Q5 Leishmania braziliensis 24% 100%
A4HLF4 Leishmania braziliensis 32% 78%
A4HMM8 Leishmania braziliensis 26% 100%
A4HRZ6 Leishmania infantum 29% 100%
A4HT82 Leishmania infantum 97% 100%
A4HTD0 Leishmania infantum 23% 75%
A4HXD4 Leishmania infantum 40% 82%
A4HY23 Leishmania infantum 24% 100%
A4I8W5 Leishmania infantum 31% 78%
A4IBA6 Leishmania infantum 27% 84%
A7GLG4 Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98) 24% 100%
A7L9Z8 Mus musculus 27% 98%
A9VFM1 Bacillus mycoides (strain KBAB4) 25% 100%
B0R9M0 Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) 24% 100%
B4U8E4 Hydrogenobaculum sp. (strain Y04AAS1) 23% 100%
B7HDF9 Bacillus cereus (strain B4264) 25% 100%
B7II09 Bacillus cereus (strain G9842) 25% 100%
B7JRB8 Bacillus cereus (strain AH820) 25% 100%
C3LF99 Bacillus anthracis (strain CDC 684 / NRRL 3495) 24% 100%
C9ZPL1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 92%
C9ZUN6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 64% 86%
C9ZZN4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 89%
D0A4V8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 84%
D0A564 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 24% 100%
D0ZTB2 Salmonella typhimurium (strain 14028s / SGSC 2262) 25% 100%
D2WKD8 Sus scrofa 28% 91%
D3K0R6 Bos taurus 38% 77%
E9AF31 Leishmania major 26% 100%
E9AJY3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 29% 100%
E9AL76 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 100%
E9AL78 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
E9ALC3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 23% 75%
E9AR29 Leishmania mexicana (strain MHOM/GT/2001/U1103) 40% 100%
E9ART6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 24% 100%
E9B3T4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 32% 78%
E9B686 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 100%
G5E829 Mus musculus 41% 76%
O14022 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 20% 85%
O14983 Homo sapiens 29% 93%
O22218 Arabidopsis thaliana 38% 90%
O23087 Arabidopsis thaliana 28% 88%
O34431 Bacillus subtilis (strain 168) 30% 100%
O43108 Yarrowia lipolytica (strain CLIB 122 / E 150) 29% 100%
O46674 Canis lupus familiaris 28% 93%
O55143 Mus musculus 28% 89%
O59868 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 30% 100%
O64806 Arabidopsis thaliana 38% 92%
O75185 Homo sapiens 28% 98%
O77696 Sus scrofa 29% 93%
O81108 Arabidopsis thaliana 39% 92%
P04074 Ovis aries 25% 91%
P04191 Oryctolagus cuniculus 29% 93%
P05023 Homo sapiens 27% 91%
P05024 Sus scrofa 26% 91%
P05025 Tetronarce californica 28% 91%
P05030 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 24% 100%
P06685 Rattus norvegicus 27% 91%
P06686 Rattus norvegicus 29% 91%
P06687 Rattus norvegicus 27% 92%
P07038 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 24% 100%
P09572 Gallus gallus 27% 91%
P09626 Rattus norvegicus 26% 90%
P09627 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 24% 100%
P0A007 Staphylococcus aureus (strain Mu50 / ATCC 700699) 23% 100%
P0A008 Staphylococcus aureus (strain N315) 23% 100%
P0ABB8 Escherichia coli (strain K12) 25% 100%
P0ABB9 Escherichia coli O157:H7 25% 100%
P11505 Rattus norvegicus 41% 76%
P11506 Rattus norvegicus 42% 75%
P11507 Rattus norvegicus 28% 89%
P11607 Sus scrofa 28% 89%
P11718 Leishmania donovani 24% 95%
P12522 Leishmania donovani 24% 95%
P13585 Gallus gallus 29% 93%
P13586 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 29% 98%
P13587 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 85%
P13607 Drosophila melanogaster 27% 89%
P13637 Homo sapiens 27% 92%
P16615 Homo sapiens 28% 89%
P17326 Artemia franciscana 28% 93%
P18596 Rattus norvegicus 29% 93%
P18907 Equus caballus 26% 91%
P19156 Sus scrofa 26% 90%
P19657 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 24% 98%
P20020 Homo sapiens 41% 76%
P20431 Arabidopsis thaliana 23% 98%
P20647 Oryctolagus cuniculus 28% 89%
P20648 Homo sapiens 26% 90%
P20649 Arabidopsis thaliana 22% 98%
P22036 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 24% 100%
P22189 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 27% 90%
P22700 Drosophila melanogaster 28% 91%
P23220 Sus scrofa 41% 76%
P23634 Homo sapiens 38% 75%
P24545 Zygosaccharomyces rouxii 25% 100%
P24797 Gallus gallus 28% 91%
P24798 Gallus gallus 27% 92%
P25489 Catostomus commersonii 27% 90%
P27112 Oryctolagus cuniculus 26% 90%
P28774 Artemia franciscana 28% 93%
P28876 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 25% 92%
P28877 Candida albicans 25% 100%
P30714 Rhinella marina 27% 91%
P35315 Trypanosoma brucei brucei 30% 92%
P35316 Artemia franciscana 28% 93%
P35317 Hydra vulgaris 28% 90%
P36640 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 25% 100%
P37278 Synechococcus elongatus (strain PCC 7942 / FACHB-805) 32% 100%
P37367 Synechocystis sp. (strain PCC 6803 / Kazusa) 28% 100%
P38929 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 34% 79%
P47317 Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) 27% 100%
P49380 Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) 25% 100%
P50993 Homo sapiens 28% 91%
P50996 Canis lupus familiaris 26% 90%
P50997 Canis lupus familiaris 26% 91%
P54209 Dunaliella bioculata 30% 90%
P54210 Dunaliella acidophila 22% 84%
P54211 Dunaliella bioculata 24% 82%
P54678 Dictyostelium discoideum 41% 83%
P54679 Dictyostelium discoideum 24% 88%
P54707 Homo sapiens 27% 89%
P54708 Rattus norvegicus 27% 90%
P57699 Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) 24% 100%
P57709 Bos taurus 27% 97%
P58165 Oreochromis mossambicus 41% 84%
P58312 Oreochromis mossambicus 26% 92%
P63688 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 30% 100%
P70083 Makaira nigricans 30% 93%
P78036 Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) 28% 100%
P83970 Triticum aestivum 22% 98%
P92939 Arabidopsis thaliana 29% 88%
P98194 Homo sapiens 27% 100%
P9WPS8 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 30% 100%
P9WPS9 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 30% 100%
Q00779 Felis catus 28% 93%
Q00804 Oryctolagus cuniculus 41% 76%
Q01814 Homo sapiens 42% 75%
Q01896 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 85%
Q03194 Nicotiana plumbaginifolia 23% 98%
Q03669 Gallus gallus 28% 89%
Q07421 Ajellomyces capsulatus 24% 100%
Q08435 Nicotiana plumbaginifolia 23% 97%
Q08436 Nicotiana plumbaginifolia 23% 97%
Q08DA1 Bos taurus 25% 91%
Q0VCY0 Bos taurus 30% 94%
Q10309 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 23% 90%
Q12691 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 85%
Q13733 Homo sapiens 29% 90%
Q16720 Homo sapiens 39% 76%
Q21286 Caenorhabditis elegans 22% 77%
Q292Q0 Drosophila pseudoobscura pseudoobscura 28% 93%
Q2QMX9 Oryza sativa subsp. japonica 37% 91%
Q2QY12 Oryza sativa subsp. japonica 38% 89%
Q2RAS0 Oryza sativa subsp. japonica 38% 91%
Q37145 Arabidopsis thaliana 38% 91%
Q42556 Arabidopsis thaliana 22% 97%
Q42883 Solanum lycopersicum 28% 89%
Q43128 Arabidopsis thaliana 24% 98%
Q4Q490 Leishmania major 32% 78%
Q4QDN7 Leishmania major 24% 100%
Q4QDN8 Leishmania major 24% 100%
Q4QED4 Leishmania major 41% 100%
Q4QIM6 Leishmania major 94% 100%
Q4QIM8 Leishmania major 97% 100%
Q4VNC1 Homo sapiens 21% 78%
Q58623 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) 25% 100%
Q5HK64 Staphylococcus epidermidis (strain ATCC 35984 / RP62A) 23% 100%
Q5R5K5 Pongo abelii 27% 100%
Q5RCD8 Pongo abelii 28% 91%
Q5RDR3 Pongo abelii 27% 91%
Q5XF90 Mus musculus 21% 78%
Q5ZKB7 Gallus gallus 22% 77%
Q63FR0 Bacillus cereus (strain ZK / E33L) 25% 100%
Q64392 Cavia porcellus 27% 90%
Q64436 Mus musculus 27% 90%
Q64518 Mus musculus 28% 93%
Q64541 Rattus norvegicus 27% 90%
Q64542 Rattus norvegicus 39% 77%
Q64566 Rattus norvegicus 27% 100%
Q64568 Rattus norvegicus 38% 74%
Q64578 Rattus norvegicus 29% 93%
Q65X71 Oryza sativa subsp. japonica 37% 91%
Q6ATV4 Oryza sativa subsp. japonica 39% 90%
Q6DFW5 Mus musculus 22% 79%
Q6GKN3 Staphylococcus aureus (strain MRSA252) 23% 100%
Q6HN78 Bacillus thuringiensis subsp. konkukian (strain 97-27) 25% 100%
Q6PIC6 Mus musculus 27% 92%
Q6PIE5 Mus musculus 29% 91%
Q6Q477 Mus musculus 39% 77%
Q6RWA9 Taenia solium 29% 92%
Q73E41 Bacillus cereus (strain ATCC 10987 / NRS 248) 29% 100%
Q7PPA5 Anopheles gambiae 29% 91%
Q7X8B5 Oryza sativa subsp. japonica 36% 85%
Q7XEK4 Oryza sativa subsp. japonica 37% 90%
Q7XPY2 Oryza sativa subsp. japonica 23% 98%
Q80XR2 Mus musculus 27% 100%
Q81HQ0 Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) 25% 100%
Q8KU73 Enterococcus faecalis (strain ATCC 700802 / V583) 21% 100%
Q8R429 Mus musculus 29% 93%
Q8R4C1 Rattus norvegicus 28% 98%
Q8RUN1 Oryza sativa subsp. japonica 38% 89%
Q8VDN2 Mus musculus 27% 91%
Q8Y8Q5 Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) 31% 100%
Q92030 Anguilla anguilla 28% 91%
Q92036 Rhinella marina 26% 89%
Q92105 Pelophylax lessonae 29% 93%
Q92123 Xenopus laevis 28% 91%
Q92126 Xenopus laevis 28% 90%
Q93084 Homo sapiens 29% 93%
Q95Z93 Leishmania major 28% 100%
Q97BF6 Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) 22% 100%
Q98SH2 Gallus gallus 39% 77%
Q9CFU9 Lactococcus lactis subsp. lactis (strain IL1403) 30% 100%
Q9CTG6 Mus musculus 23% 79%
Q9HDW7 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 40% 72%
Q9LF79 Arabidopsis thaliana 38% 86%
Q9LIK7 Arabidopsis thaliana 36% 91%
Q9LU41 Arabidopsis thaliana 36% 86%
Q9LY77 Arabidopsis thaliana 37% 90%
Q9M2A0 Arabidopsis thaliana 23% 98%
Q9M2L4 Arabidopsis thaliana 39% 91%
Q9N0Z6 Oryctolagus cuniculus 27% 91%
Q9NQ11 Homo sapiens 23% 79%
Q9R0K7 Mus musculus 38% 78%
Q9SJB3 Arabidopsis thaliana 22% 98%
Q9SU58 Arabidopsis thaliana 23% 97%
Q9SY55 Arabidopsis thaliana 30% 93%
Q9SZR1 Arabidopsis thaliana 37% 87%
Q9TV52 Oryctolagus cuniculus 29% 85%
Q9WV27 Mus musculus 27% 90%
Q9XES1 Arabidopsis thaliana 29% 88%
Q9Y2G3 Homo sapiens 22% 79%
Q9YGL9 Gallus gallus 29% 93%
Q9YH26 Oreochromis mossambicus 28% 91%
Q9Z1W8 Mus musculus 27% 90%
V5B873 Trypanosoma cruzi 71% 84%
V5BHZ2 Trypanosoma cruzi 27% 89%
V5BLM1 Trypanosoma cruzi 30% 92%
V5BPC6 Trypanosoma cruzi 36% 88%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS