Putative nucleolar RNA-binding protein

Quick info Annotations Localization Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA binding protein - putative

Species:

Leishmania infantum

UniProt:

A4HTC3_LEIIN

TriTrypDb:

LINF_070016100

Length:

209

Annotations

Annotations by Jardim et al.

Nuclear proteins, nucleolar RNA-binding

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4HTC3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HTC3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	13	17	PF00082	0.135
CLV_PCSK_SKI1_1	49	53	PF00082	0.135
DEG_Kelch_Keap1_1	173	178	PF01344	0.425
DEG_Nend_UBRbox_2	1	3	PF02207	0.249
DOC_CYCLIN_yCln2_LP_2	30	36	PF00134	0.135
DOC_PP2B_LxvP_1	30	33	PF13499	0.135
DOC_USP7_MATH_1	107	111	PF00917	0.423
DOC_USP7_MATH_1	143	147	PF00917	0.448
DOC_WW_Pin1_4	132	137	PF00397	0.437
LIG_14-3-3_CanoR_1	26	33	PF00244	0.135
LIG_Actin_WH2_2	12	28	PF00022	0.135
LIG_FHA_1	65	71	PF00498	0.135
LIG_FHA_1	88	94	PF00498	0.135
LIG_FHA_2	174	180	PF00498	0.428
LIG_LIR_Apic_2	90	95	PF02991	0.135
LIG_LIR_LC3C_4	41	44	PF02991	0.135
LIG_LIR_Nem_3	2	7	PF02991	0.135
LIG_SH2_PTP2	92	95	PF00017	0.257
LIG_SH2_STAT5	92	95	PF00017	0.257
LIG_TRAF2_1	110	113	PF00917	0.442
LIG_TRAF2_1	146	149	PF00917	0.442
LIG_TRAF2_1	176	179	PF00917	0.433
LIG_WRC_WIRS_1	43	48	PF05994	0.135
MOD_CK2_1	107	113	PF00069	0.432
MOD_CK2_1	122	128	PF00069	0.445
MOD_CK2_1	143	149	PF00069	0.448
MOD_CK2_1	173	179	PF00069	0.427
MOD_GlcNHglycan	109	112	PF01048	0.435
MOD_GlcNHglycan	137	140	PF01048	0.446
MOD_GlcNHglycan	79	82	PF01048	0.135
MOD_GSK3_1	122	129	PF00069	0.443
MOD_GSK3_1	38	45	PF00069	0.135
MOD_NEK2_1	25	30	PF00069	0.135
MOD_PIKK_1	25	31	PF00454	0.135
MOD_PKA_2	25	31	PF00069	0.135
MOD_Plk_1	75	81	PF00069	0.135
MOD_Plk_2-3	113	119	PF00069	0.451
MOD_Plk_2-3	122	128	PF00069	0.445
MOD_Plk_4	38	44	PF00069	0.135
MOD_ProDKin_1	132	138	PF00069	0.438
MOD_SUMO_rev_2	41	51	PF00179	0.135

Homologs


Protein	Taxonomy	Sequence identity	Coverage
P0C1J6	RHIO9	34%	55%