Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HT86_LEIIN

TriTrypDb:

LINF_070011700

Length:

250

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HT86

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HT86

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	12	16	PF00656	0.524
CLV_PCSK_KEX2_1	146	148	PF00082	0.633
CLV_PCSK_KEX2_1	215	217	PF00082	0.782
CLV_PCSK_PC1ET2_1	146	148	PF00082	0.633
CLV_PCSK_PC1ET2_1	215	217	PF00082	0.771
DEG_SPOP_SBC_1	124	128	PF00917	0.746
DOC_CKS1_1	140	145	PF01111	0.699
DOC_CYCLIN_yCln2_LP_2	26	32	PF00134	0.481
DOC_MAPK_JIP1_4	2	8	PF00069	0.573
DOC_PP1_RVXF_1	180	186	PF00149	0.439
DOC_PP2B_LxvP_1	26	29	PF13499	0.561
DOC_PP4_FxxP_1	8	11	PF00568	0.507
DOC_USP7_MATH_1	118	122	PF00917	0.726
DOC_USP7_MATH_1	124	128	PF00917	0.734
DOC_USP7_MATH_1	134	138	PF00917	0.461
DOC_USP7_MATH_1	156	160	PF00917	0.613
DOC_USP7_MATH_1	225	229	PF00917	0.712
DOC_USP7_MATH_1	53	57	PF00917	0.767
DOC_WW_Pin1_4	139	144	PF00397	0.627
DOC_WW_Pin1_4	244	249	PF00397	0.396
LIG_14-3-3_CanoR_1	158	165	PF00244	0.556
LIG_14-3-3_CanoR_1	180	186	PF00244	0.474
LIG_FHA_1	23	29	PF00498	0.459
LIG_FHA_1	235	241	PF00498	0.465
LIG_FHA_1	34	40	PF00498	0.400
LIG_FHA_1	67	73	PF00498	0.749
LIG_FHA_1	81	87	PF00498	0.580
LIG_FHA_2	140	146	PF00498	0.652
LIG_FHA_2	174	180	PF00498	0.536
LIG_LIR_Gen_1	167	174	PF02991	0.434
LIG_LIR_Nem_3	167	172	PF02991	0.427
LIG_Pex14_2	165	169	PF04695	0.553
LIG_RPA_C_Fungi	197	209	PF08784	0.652
LIG_SH2_STAP1	144	148	PF00017	0.635
LIG_SH2_STAT5	103	106	PF00017	0.525
LIG_SH3_3	137	143	PF00018	0.730
LIG_SH3_3	25	31	PF00018	0.450
LIG_SUMO_SIM_anti_2	239	245	PF11976	0.459
LIG_SUMO_SIM_par_1	235	241	PF11976	0.483
MOD_CDK_SPxxK_3	139	146	PF00069	0.519
MOD_CK1_1	123	129	PF00069	0.668
MOD_CK1_1	71	77	PF00069	0.687
MOD_CK2_1	173	179	PF00069	0.534
MOD_Cter_Amidation	213	216	PF01082	0.715
MOD_GlcNHglycan	120	123	PF01048	0.721
MOD_GlcNHglycan	127	130	PF01048	0.693
MOD_GlcNHglycan	158	161	PF01048	0.606
MOD_GlcNHglycan	166	169	PF01048	0.505
MOD_GlcNHglycan	18	22	PF01048	0.552
MOD_GlcNHglycan	229	232	PF01048	0.628
MOD_GlcNHglycan	39	42	PF01048	0.447
MOD_GlcNHglycan	51	54	PF01048	0.544
MOD_GlcNHglycan	97	100	PF01048	0.561
MOD_GSK3_1	120	127	PF00069	0.635
MOD_GSK3_1	134	141	PF00069	0.590
MOD_GSK3_1	234	241	PF00069	0.435
MOD_GSK3_1	33	40	PF00069	0.437
MOD_GSK3_1	49	56	PF00069	0.591
MOD_GSK3_1	68	75	PF00069	0.699
MOD_GSK3_1	9	16	PF00069	0.541
MOD_GSK3_1	95	102	PF00069	0.472
MOD_N-GLC_1	200	205	PF02516	0.718
MOD_NEK2_1	112	117	PF00069	0.617
MOD_NEK2_1	183	188	PF00069	0.488
MOD_NEK2_1	37	42	PF00069	0.402
MOD_PIKK_1	173	179	PF00454	0.534
MOD_PKA_2	13	19	PF00069	0.511
MOD_PKA_2	181	187	PF00069	0.477
MOD_Plk_1	200	206	PF00069	0.692
MOD_Plk_1	234	240	PF00069	0.459
MOD_Plk_4	238	244	PF00069	0.440
MOD_Plk_4	72	78	PF00069	0.615
MOD_ProDKin_1	139	145	PF00069	0.620
MOD_ProDKin_1	244	250	PF00069	0.412
MOD_SUMO_rev_2	226	231	PF00179	0.662
TRG_ER_diArg_1	180	183	PF00400	0.515
TRG_Pf-PMV_PEXEL_1	215	219	PF00026	0.776

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P403	Leptomonas seymouri	45%	96%
A0A1X0NPF9	Trypanosomatidae	26%	100%
A0A3R7K387	Trypanosoma rangeli	28%	100%
A0A3S5H5Y8	Leishmania donovani	98%	100%
A4H512	Leishmania braziliensis	67%	98%
C9ZUN8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
E9AL74	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4QIN0	Leishmania major	84%	100%