Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HT81_LEIIN

TriTrypDb:

LINF_070010200

Length:

159


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	8
GO:0110165	cellular anatomical entity	1	8

A4HT81

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HT81


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	115	117	PF00082	0.334
CLV_PCSK_PC1ET2_1	115	117	PF00082	0.317
CLV_PCSK_SKI1_1	115	119	PF00082	0.417
CLV_PCSK_SKI1_1	12	16	PF00082	0.358
CLV_PCSK_SKI1_1	64	68	PF00082	0.567
CLV_PCSK_SKI1_1	95	99	PF00082	0.346
DOC_MAPK_DCC_7	75	83	PF00069	0.263
DOC_MAPK_gen_1	100	107	PF00069	0.534
DOC_MAPK_gen_1	9	17	PF00069	0.530
DOC_MAPK_MEF2A_6	100	107	PF00069	0.534
DOC_MAPK_MEF2A_6	75	83	PF00069	0.245
DOC_WW_Pin1_4	152	157	PF00397	0.602
LIG_Actin_WH2_2	125	142	PF00022	0.492
LIG_Actin_WH2_2	99	117	PF00022	0.492
LIG_FHA_1	153	159	PF00498	0.715
LIG_FHA_1	49	55	PF00498	0.423
LIG_LIR_Apic_2	70	76	PF02991	0.344
LIG_LIR_Gen_1	148	157	PF02991	0.604
LIG_LIR_Gen_1	37	48	PF02991	0.527
LIG_LIR_Nem_3	148	152	PF02991	0.563
LIG_LIR_Nem_3	37	43	PF02991	0.548
LIG_Pex14_1	40	44	PF04695	0.555
LIG_PTB_Apo_2	66	73	PF02174	0.352
LIG_PTB_Phospho_1	66	72	PF10480	0.353
LIG_SH2_CRK	73	77	PF00017	0.346
LIG_SH2_STAP1	110	114	PF00017	0.506
LIG_SH2_STAT5	13	16	PF00017	0.510
LIG_SH2_STAT5	42	45	PF00017	0.281
LIG_SH3_1	73	79	PF00018	0.343
LIG_SH3_3	73	79	PF00018	0.343
LIG_SUMO_SIM_par_1	13	18	PF11976	0.585
MOD_CDK_SPxxK_3	152	159	PF00069	0.615
MOD_CK1_1	50	56	PF00069	0.365
MOD_NEK2_1	15	20	PF00069	0.570
MOD_NEK2_1	67	72	PF00069	0.400
MOD_PIKK_1	124	130	PF00454	0.570
MOD_PIKK_1	15	21	PF00454	0.560
MOD_PKA_2	8	14	PF00069	0.488
MOD_Plk_1	15	21	PF00069	0.571
MOD_Plk_4	50	56	PF00069	0.328
MOD_Plk_4	67	73	PF00069	0.352
MOD_ProDKin_1	152	158	PF00069	0.606
MOD_SUMO_rev_2	108	117	PF00179	0.501
TRG_ER_diArg_1	7	10	PF00400	0.539
TRG_ER_diArg_1	99	102	PF00400	0.520


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4IUG7	Bodo saltans	64%	95%
A0A1X0NPB3	Trypanosomatidae	72%	100%
A0A3S7WPV0	Leishmania donovani	100%	100%
A4H4Z7	Leishmania braziliensis	94%	100%
C9ZUQ4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	74%	95%
E9AL59	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
Q4QIP5	Leishmania major	99%	100%
V5BYF1	Trypanosoma cruzi	70%	100%