CLASP_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HT26_LEIIN

TriTrypDb:

LINF_070005400

Length:

314

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HT26

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HT26

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	170	174	PF00656	0.600
CLV_NRD_NRD_1	224	226	PF00675	0.702
CLV_NRD_NRD_1	241	243	PF00675	0.480
CLV_NRD_NRD_1	299	301	PF00675	0.644
CLV_PCSK_FUR_1	297	301	PF00082	0.770
CLV_PCSK_KEX2_1	239	241	PF00082	0.684
CLV_PCSK_KEX2_1	296	298	PF00082	0.623
CLV_PCSK_KEX2_1	299	301	PF00082	0.639
CLV_PCSK_KEX2_1	53	55	PF00082	0.511
CLV_PCSK_PC1ET2_1	239	241	PF00082	0.684
CLV_PCSK_PC1ET2_1	296	298	PF00082	0.623
CLV_PCSK_PC1ET2_1	53	55	PF00082	0.511
CLV_PCSK_SKI1_1	102	106	PF00082	0.581
CLV_PCSK_SKI1_1	153	157	PF00082	0.455
CLV_PCSK_SKI1_1	212	216	PF00082	0.598
CLV_PCSK_SKI1_1	226	230	PF00082	0.557
CLV_PCSK_SKI1_1	300	304	PF00082	0.779
CLV_PCSK_SKI1_1	77	81	PF00082	0.539
DEG_APCC_DBOX_1	148	156	PF00400	0.488
DEG_APCC_DBOX_1	211	219	PF00400	0.589
DEG_APCC_DBOX_1	76	84	PF00400	0.367
DEG_SPOP_SBC_1	168	172	PF00917	0.492
DOC_CKS1_1	177	182	PF01111	0.678
DOC_CYCLIN_RxL_1	74	84	PF00134	0.377
DOC_MAPK_gen_1	102	112	PF00069	0.560
DOC_MAPK_gen_1	149	157	PF00069	0.426
DOC_MAPK_gen_1	296	306	PF00069	0.636
DOC_MAPK_gen_1	53	62	PF00069	0.540
DOC_MAPK_MEF2A_6	105	114	PF00069	0.423
DOC_MAPK_MEF2A_6	297	306	PF00069	0.615
DOC_PP1_RVXF_1	130	136	PF00149	0.463
DOC_USP7_MATH_1	168	172	PF00917	0.635
DOC_WW_Pin1_4	119	124	PF00397	0.411
DOC_WW_Pin1_4	176	181	PF00397	0.617
DOC_WW_Pin1_4	200	205	PF00397	0.644
DOC_WW_Pin1_4	270	275	PF00397	0.746
DOC_WW_Pin1_4	290	295	PF00397	0.508
DOC_WW_Pin1_4	306	311	PF00397	0.623
DOC_WW_Pin1_4	4	9	PF00397	0.585
LIG_14-3-3_CanoR_1	100	105	PF00244	0.576
LIG_14-3-3_CanoR_1	118	122	PF00244	0.297
LIG_14-3-3_CanoR_1	169	177	PF00244	0.606
LIG_14-3-3_CanoR_1	225	235	PF00244	0.625
LIG_14-3-3_CanoR_1	299	305	PF00244	0.628
LIG_Actin_WH2_2	103	120	PF00022	0.553
LIG_BIR_II_1	1	5	PF00653	0.515
LIG_FHA_1	120	126	PF00498	0.416
LIG_FHA_1	21	27	PF00498	0.570
LIG_FHA_1	227	233	PF00498	0.628
LIG_FHA_1	275	281	PF00498	0.634
LIG_FHA_1	301	307	PF00498	0.778
LIG_FHA_1	56	62	PF00498	0.567
LIG_FHA_1	73	79	PF00498	0.313
LIG_FHA_1	99	105	PF00498	0.393
LIG_FHA_2	142	148	PF00498	0.559
LIG_FHA_2	253	259	PF00498	0.667
LIG_FHA_2	273	279	PF00498	0.540
LIG_FHA_2	83	89	PF00498	0.370
LIG_NRBOX	85	91	PF00104	0.510
LIG_SH2_STAT5	235	238	PF00017	0.549
LIG_SH3_2	307	312	PF14604	0.626
LIG_SH3_3	174	180	PF00018	0.788
LIG_SH3_3	202	208	PF00018	0.627
LIG_SH3_3	268	274	PF00018	0.765
LIG_SH3_3	301	307	PF00018	0.655
LIG_SH3_CIN85_PxpxPR_1	180	185	PF14604	0.578
LIG_SUMO_SIM_par_1	287	293	PF11976	0.614
LIG_SxIP_EBH_1	225	238	PF03271	0.692
LIG_UBA3_1	288	296	PF00899	0.609
MOD_CDC14_SPxK_1	293	296	PF00782	0.611
MOD_CDC14_SPxK_1	309	312	PF00782	0.629
MOD_CDK_SPxK_1	290	296	PF00069	0.612
MOD_CDK_SPxK_1	306	312	PF00069	0.627
MOD_CDK_SPxxK_3	178	185	PF00069	0.574
MOD_CDK_SPxxK_3	290	297	PF00069	0.612
MOD_CK1_1	141	147	PF00069	0.622
MOD_CK1_1	251	257	PF00069	0.754
MOD_CK1_1	68	74	PF00069	0.565
MOD_CK2_1	133	139	PF00069	0.480
MOD_CK2_1	141	147	PF00069	0.474
MOD_CK2_1	190	196	PF00069	0.613
MOD_CK2_1	252	258	PF00069	0.598
MOD_CK2_1	82	88	PF00069	0.369
MOD_GlcNHglycan	139	143	PF01048	0.629
MOD_GlcNHglycan	229	232	PF01048	0.568
MOD_GlcNHglycan	27	30	PF01048	0.501
MOD_GlcNHglycan	65	68	PF01048	0.635
MOD_GlcNHglycan	91	94	PF01048	0.395
MOD_GSK3_1	117	124	PF00069	0.556
MOD_GSK3_1	196	203	PF00069	0.766
MOD_GSK3_1	227	234	PF00069	0.573
MOD_GSK3_1	248	255	PF00069	0.740
MOD_GSK3_1	270	277	PF00069	0.629
MOD_GSK3_1	65	72	PF00069	0.537
MOD_N-GLC_1	300	305	PF02516	0.711
MOD_NEK2_1	116	121	PF00069	0.414
MOD_NEK2_1	138	143	PF00069	0.617
MOD_NEK2_1	167	172	PF00069	0.589
MOD_NEK2_1	89	94	PF00069	0.388
MOD_PIKK_1	55	61	PF00454	0.503
MOD_PKA_1	197	203	PF00069	0.571
MOD_PKA_2	117	123	PF00069	0.552
MOD_PKA_2	168	174	PF00069	0.707
MOD_PKA_2	248	254	PF00069	0.569
MOD_PKA_2	55	61	PF00069	0.538
MOD_PKB_1	240	248	PF00069	0.641
MOD_PKB_1	298	306	PF00069	0.742
MOD_PKB_1	98	106	PF00069	0.573
MOD_Plk_1	216	222	PF00069	0.555
MOD_Plk_1	243	249	PF00069	0.649
MOD_Plk_1	300	306	PF00069	0.779
MOD_Plk_2-3	22	28	PF00069	0.531
MOD_Plk_4	121	127	PF00069	0.539
MOD_Plk_4	231	237	PF00069	0.549
MOD_ProDKin_1	119	125	PF00069	0.410
MOD_ProDKin_1	176	182	PF00069	0.619
MOD_ProDKin_1	200	206	PF00069	0.641
MOD_ProDKin_1	270	276	PF00069	0.746
MOD_ProDKin_1	290	296	PF00069	0.509
MOD_ProDKin_1	306	312	PF00069	0.627
MOD_ProDKin_1	4	10	PF00069	0.584
MOD_SUMO_rev_2	193	200	PF00179	0.763
TRG_DiLeu_BaEn_1	57	62	PF01217	0.574
TRG_DiLeu_BaLyEn_6	74	79	PF01217	0.397
TRG_ER_diArg_1	240	242	PF00400	0.600
TRG_ER_diArg_1	297	300	PF00400	0.629
TRG_NLS_Bipartite_1	225	243	PF00514	0.702
TRG_NLS_MonoCore_2	238	243	PF00514	0.726
TRG_NLS_MonoCore_2	295	300	PF00514	0.614
TRG_NLS_MonoExtC_3	238	244	PF00514	0.729
TRG_NLS_MonoExtC_3	295	300	PF00514	0.625
TRG_NLS_MonoExtN_4	294	300	PF00514	0.623
TRG_Pf-PMV_PEXEL_1	287	292	PF00026	0.673
TRG_Pf-PMV_PEXEL_1	300	305	PF00026	0.563
TRG_Pf-PMV_PEXEL_1	77	81	PF00026	0.375

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZD5	Leptomonas seymouri	40%	100%
A0A3S7WPQ1	Leishmania donovani	100%	100%
A4H4U7	Leishmania braziliensis	73%	100%
E9AL14	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
Q4QIU0	Leishmania major	90%	100%