NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HSV9_LEIIN

TriTrypDb:

LINF_060012400

Length:

243

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

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Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	1
GO:0005743	mitochondrial inner membrane	5	8
GO:0005758	mitochondrial intermembrane space	6	8
GO:0016020	membrane	2	8
GO:0019866	organelle inner membrane	4	8
GO:0031090	organelle membrane	3	8
GO:0031966	mitochondrial membrane	4	8
GO:0031970	organelle envelope lumen	5	8
GO:0031974	membrane-enclosed lumen	2	8
GO:0043226	organelle	2	1

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Expansion

Sequence features

A4HSV9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HSV9

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	21	25	PF00656	0.753
CLV_C14_Caspase3-7	38	42	PF00656	0.474
CLV_NRD_NRD_1	65	67	PF00675	0.546
CLV_PCSK_KEX2_1	65	67	PF00082	0.567
CLV_PCSK_PC1ET2_1	65	67	PF00082	0.530
DEG_SCF_FBW7_1	44	51	PF00400	0.646
DEG_SPOP_SBC_1	18	22	PF00917	0.588
DEG_SPOP_SBC_1	8	12	PF00917	0.621
DOC_CKS1_1	56	61	PF01111	0.580
DOC_MAPK_gen_1	203	210	PF00069	0.531

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5D1	Leptomonas seymouri	65%	100%
A0A0S4J9I1	Bodo saltans	51%	100%
A0A1X0NL39	Trypanosomatidae	54%	100%
A0A3S5H5R9	Leishmania donovani	100%	100%
A4H4N3	Leishmania braziliensis	80%	100%
C9ZTH2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	100%
E9AKU7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4QJ10	Leishmania major	92%	100%

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