NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HSV9_LEIIN

TriTrypDb:

LINF_060012400

Length:

243

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005743	mitochondrial inner membrane	5	8
GO:0005758	mitochondrial intermembrane space	6	8
GO:0016020	membrane	2	8
GO:0019866	organelle inner membrane	4	8
GO:0031090	organelle membrane	3	8
GO:0031966	mitochondrial membrane	4	8
GO:0031970	organelle envelope lumen	5	8
GO:0031974	membrane-enclosed lumen	2	8
GO:0043233	organelle lumen	3	8
GO:0070013	intracellular organelle lumen	4	8
GO:0070469	respirasome	2	8
GO:0110165	cellular anatomical entity	1	9
GO:0005739	mitochondrion	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

A4HSV9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HSV9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	21	25	PF00656	0.753
CLV_C14_Caspase3-7	38	42	PF00656	0.474
CLV_NRD_NRD_1	65	67	PF00675	0.546
CLV_PCSK_KEX2_1	65	67	PF00082	0.567
CLV_PCSK_PC1ET2_1	65	67	PF00082	0.530
DEG_SCF_FBW7_1	44	51	PF00400	0.646
DEG_SPOP_SBC_1	18	22	PF00917	0.588
DEG_SPOP_SBC_1	8	12	PF00917	0.621
DOC_CKS1_1	56	61	PF01111	0.580
DOC_MAPK_gen_1	203	210	PF00069	0.531
DOC_PP2B_LxvP_1	124	127	PF13499	0.585
DOC_USP7_MATH_1	3	7	PF00917	0.673
DOC_USP7_MATH_1	48	52	PF00917	0.626
DOC_USP7_MATH_1	8	12	PF00917	0.688
DOC_USP7_MATH_1	81	85	PF00917	0.636
DOC_USP7_MATH_1	96	100	PF00917	0.585
DOC_WW_Pin1_4	44	49	PF00397	0.657
DOC_WW_Pin1_4	55	60	PF00397	0.598
DOC_WW_Pin1_4	71	76	PF00397	0.623
LIG_14-3-3_CanoR_1	80	86	PF00244	0.548
LIG_CaM_IQ_9	131	146	PF13499	0.396
LIG_deltaCOP1_diTrp_1	159	165	PF00928	0.417
LIG_FHA_1	45	51	PF00498	0.546
LIG_FHA_2	135	141	PF00498	0.501
LIG_FHA_2	19	25	PF00498	0.640
LIG_FHA_2	56	62	PF00498	0.570
LIG_LIR_Gen_1	113	123	PF02991	0.488
LIG_LIR_Gen_1	172	181	PF02991	0.458
LIG_LIR_Nem_3	113	118	PF02991	0.506
LIG_LIR_Nem_3	172	178	PF02991	0.466
LIG_Pex14_1	226	230	PF04695	0.455
LIG_PTB_Apo_2	109	116	PF02174	0.588
LIG_SH3_1	187	193	PF00018	0.573
LIG_SH3_3	187	193	PF00018	0.608
LIG_TRAF2_1	58	61	PF00917	0.568
LIG_TYR_ITSM	171	178	PF00017	0.464
LIG_WRC_WIRS_1	199	204	PF05994	0.464
MOD_CDK_SPxxK_3	71	78	PF00069	0.628
MOD_CK1_1	10	16	PF00069	0.604
MOD_CK1_1	37	43	PF00069	0.670
MOD_CK1_1	51	57	PF00069	0.541
MOD_CK2_1	54	60	PF00069	0.591
MOD_CMANNOS	162	165	PF00535	0.411
MOD_GlcNHglycan	12	15	PF01048	0.637
MOD_GlcNHglycan	90	93	PF01048	0.673
MOD_GlcNHglycan	97	101	PF01048	0.604
MOD_GSK3_1	3	10	PF00069	0.651
MOD_GSK3_1	44	51	PF00069	0.604
MOD_NEK2_1	134	139	PF00069	0.529
MOD_NEK2_1	161	166	PF00069	0.440
MOD_NEK2_1	198	203	PF00069	0.463
MOD_NEK2_2	81	86	PF00069	0.516
MOD_NMyristoyl	1	7	PF02799	0.567
MOD_PKA_2	170	176	PF00069	0.465
MOD_PKA_2	87	93	PF00069	0.628
MOD_Plk_1	149	155	PF00069	0.459
MOD_Plk_1	48	54	PF00069	0.671
MOD_Plk_2-3	114	120	PF00069	0.486
MOD_Plk_4	170	176	PF00069	0.492
MOD_ProDKin_1	44	50	PF00069	0.660
MOD_ProDKin_1	55	61	PF00069	0.594
MOD_ProDKin_1	71	77	PF00069	0.622
TRG_ENDOCYTIC_2	175	178	PF00928	0.526
TRG_ENDOCYTIC_2	69	72	PF00928	0.494
TRG_ER_diArg_1	78	81	PF00400	0.607
TRG_Pf-PMV_PEXEL_1	155	159	PF00026	0.432
TRG_Pf-PMV_PEXEL_1	184	189	PF00026	0.590

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5D1	Leptomonas seymouri	65%	100%
A0A0S4J9I1	Bodo saltans	51%	100%
A0A1X0NL39	Trypanosomatidae	54%	100%
A0A3S5H5R9	Leishmania donovani	100%	100%
A4H4N3	Leishmania braziliensis	80%	100%
C9ZTH2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	100%
E9AKU7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4QJ10	Leishmania major	92%	100%