Condensin complex subunit 2

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania infantum

UniProt:

A4HST9_LEIIN

TriTrypDb:

LINF_060010200

Length:

1157

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0000796	condensin complex	3	6
GO:0005737	cytoplasm	2	6
GO:0032991	protein-containing complex	1	6
GO:0044815	DNA packaging complex	2	6
GO:0110165	cellular anatomical entity	1	6
GO:0005654	nucleoplasm	2	1

Expansion

Sequence features

A4HST9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HST9

Function

Biological processes
Term	Name	Level	Count
GO:0006996	organelle organization	4	6
GO:0007076	mitotic chromosome condensation	4	6
GO:0009987	cellular process	1	6
GO:0016043	cellular component organization	3	6
GO:0022402	cell cycle process	2	6
GO:0030261	chromosome condensation	6	6
GO:0051276	chromosome organization	5	6
GO:0051301	cell division	2	6
GO:0071840	cellular component organization or biogenesis	2	6
GO:1903047	mitotic cell cycle process	3	6

Molecular functions
Term	Name	Level	Count
GO:0003682	chromatin binding	2	1
GO:0005488	binding	1	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	141	145	PF00656	0.547
CLV_C14_Caspase3-7	170	174	PF00656	0.533
CLV_C14_Caspase3-7	205	209	PF00656	0.499
CLV_C14_Caspase3-7	305	309	PF00656	0.496
CLV_C14_Caspase3-7	403	407	PF00656	0.645
CLV_C14_Caspase3-7	506	510	PF00656	0.632
CLV_C14_Caspase3-7	562	566	PF00656	0.497
CLV_C14_Caspase3-7	870	874	PF00656	0.665
CLV_C14_Caspase3-7	910	914	PF00656	0.543
CLV_C14_Caspase3-7	943	947	PF00656	0.618
CLV_MEL_PAP_1	1151	1157	PF00089	0.580
CLV_NRD_NRD_1	1026	1028	PF00675	0.613
CLV_NRD_NRD_1	187	189	PF00675	0.288
CLV_NRD_NRD_1	316	318	PF00675	0.256
CLV_NRD_NRD_1	37	39	PF00675	0.705
CLV_NRD_NRD_1	552	554	PF00675	0.661
CLV_NRD_NRD_1	653	655	PF00675	0.678
CLV_NRD_NRD_1	782	784	PF00675	0.562
CLV_PCSK_KEX2_1	316	318	PF00082	0.256
CLV_PCSK_KEX2_1	37	39	PF00082	0.705
CLV_PCSK_KEX2_1	552	554	PF00082	0.661
CLV_PCSK_KEX2_1	651	653	PF00082	0.733
CLV_PCSK_PC1ET2_1	651	653	PF00082	0.659
CLV_PCSK_PC7_1	312	318	PF00082	0.256
CLV_PCSK_SKI1_1	1102	1106	PF00082	0.491
CLV_PCSK_SKI1_1	156	160	PF00082	0.328
CLV_PCSK_SKI1_1	252	256	PF00082	0.328
CLV_PCSK_SKI1_1	265	269	PF00082	0.245
CLV_PCSK_SKI1_1	690	694	PF00082	0.644
CLV_PCSK_SKI1_1	699	703	PF00082	0.549
CLV_PCSK_SKI1_1	706	710	PF00082	0.412
CLV_PCSK_SKI1_1	713	717	PF00082	0.423
CLV_PCSK_SKI1_1	784	788	PF00082	0.593
DEG_APCC_DBOX_1	1101	1109	PF00400	0.492
DEG_APCC_DBOX_1	427	435	PF00400	0.617
DEG_SPOP_SBC_1	1110	1114	PF00917	0.435
DEG_SPOP_SBC_1	771	775	PF00917	0.540
DEG_SPOP_SBC_1	803	807	PF00917	0.680
DOC_ANK_TNKS_1	200	207	PF00023	0.496
DOC_CKS1_1	1	6	PF01111	0.700
DOC_CYCLIN_yCln2_LP_2	638	644	PF00134	0.583
DOC_CYCLIN_yCln2_LP_2	949	955	PF00134	0.614
DOC_MAPK_DCC_7	1102	1110	PF00069	0.374
DOC_MAPK_gen_1	651	661	PF00069	0.676
DOC_MAPK_MEF2A_6	1102	1110	PF00069	0.374
DOC_MAPK_MEF2A_6	288	296	PF00069	0.529
DOC_PP1_RVXF_1	655	662	PF00149	0.676
DOC_PP1_RVXF_1	711	718	PF00149	0.496
DOC_PP1_RVXF_1	974	981	PF00149	0.426
DOC_PP2B_LxvP_1	419	422	PF13499	0.672
DOC_PP2B_LxvP_1	743	746	PF13499	0.549
DOC_PP2B_LxvP_1	959	962	PF13499	0.629
DOC_PP2B_PxIxI_1	1105	1111	PF00149	0.378
DOC_PP4_FxxP_1	661	664	PF00568	0.671
DOC_PP4_FxxP_1	768	771	PF00568	0.488
DOC_USP7_MATH_1	1007	1011	PF00917	0.715
DOC_USP7_MATH_1	122	126	PF00917	0.543
DOC_USP7_MATH_1	226	230	PF00917	0.488
DOC_USP7_MATH_1	266	270	PF00917	0.529
DOC_USP7_MATH_1	394	398	PF00917	0.663
DOC_USP7_MATH_1	407	411	PF00917	0.595
DOC_USP7_MATH_1	435	439	PF00917	0.646
DOC_USP7_MATH_1	480	484	PF00917	0.682
DOC_USP7_MATH_1	54	58	PF00917	0.668
DOC_USP7_MATH_1	673	677	PF00917	0.668
DOC_USP7_MATH_1	686	690	PF00917	0.537
DOC_USP7_MATH_1	803	807	PF00917	0.748
DOC_USP7_MATH_1	810	814	PF00917	0.703
DOC_USP7_MATH_1	926	930	PF00917	0.584
DOC_USP7_UBL2_3	651	655	PF12436	0.613
DOC_WW_Pin1_4	1085	1090	PF00397	0.657
DOC_WW_Pin1_4	1115	1120	PF00397	0.534
DOC_WW_Pin1_4	16	21	PF00397	0.692
DOC_WW_Pin1_4	25	30	PF00397	0.615
DOC_WW_Pin1_4	322	327	PF00397	0.496
DOC_WW_Pin1_4	340	345	PF00397	0.409
DOC_WW_Pin1_4	422	427	PF00397	0.671
DOC_WW_Pin1_4	637	642	PF00397	0.665
DOC_WW_Pin1_4	663	668	PF00397	0.657
DOC_WW_Pin1_4	70	75	PF00397	0.691
DOC_WW_Pin1_4	706	711	PF00397	0.556
DOC_WW_Pin1_4	957	962	PF00397	0.625
LIG_14-3-3_CanoR_1	1096	1104	PF00244	0.476
LIG_14-3-3_CanoR_1	221	226	PF00244	0.529
LIG_14-3-3_CanoR_1	252	260	PF00244	0.529
LIG_14-3-3_CanoR_1	346	353	PF00244	0.529
LIG_14-3-3_CanoR_1	436	440	PF00244	0.687
LIG_14-3-3_CanoR_1	634	639	PF00244	0.562
LIG_14-3-3_CanoR_1	699	708	PF00244	0.604
LIG_14-3-3_CanoR_1	783	791	PF00244	0.605
LIG_14-3-3_CanoR_1	98	103	PF00244	0.589
LIG_Actin_WH2_2	368	385	PF00022	0.655
LIG_Actin_WH2_2	769	785	PF00022	0.570
LIG_BIR_III_4	406	410	PF00653	0.684
LIG_BRCT_BRCA1_1	1117	1121	PF00533	0.468
LIG_BRCT_BRCA1_1	1124	1128	PF00533	0.377
LIG_BRCT_BRCA1_1	387	391	PF00533	0.670
LIG_BRCT_BRCA1_1	56	60	PF00533	0.670
LIG_EVH1_2	1093	1097	PF00568	0.476
LIG_FHA_1	1112	1118	PF00498	0.488
LIG_FHA_1	134	140	PF00498	0.552
LIG_FHA_1	167	173	PF00498	0.529
LIG_FHA_1	17	23	PF00498	0.695
LIG_FHA_1	233	239	PF00498	0.512
LIG_FHA_1	371	377	PF00498	0.641
LIG_FHA_1	785	791	PF00498	0.615
LIG_FHA_1	943	949	PF00498	0.625
LIG_FHA_2	1063	1069	PF00498	0.638
LIG_FHA_2	139	145	PF00498	0.544
LIG_FHA_2	157	163	PF00498	0.412
LIG_FHA_2	335	341	PF00498	0.444
LIG_FHA_2	360	366	PF00498	0.631
LIG_FHA_2	538	544	PF00498	0.684
LIG_FHA_2	941	947	PF00498	0.619
LIG_FHA_2	99	105	PF00498	0.562
LIG_LIR_Apic_2	658	664	PF02991	0.672
LIG_LIR_Apic_2	765	771	PF02991	0.608
LIG_LIR_Gen_1	1095	1105	PF02991	0.445
LIG_LIR_Gen_1	295	306	PF02991	0.529
LIG_LIR_Gen_1	777	786	PF02991	0.513
LIG_LIR_Gen_1	883	890	PF02991	0.653
LIG_LIR_Nem_3	1095	1100	PF02991	0.444
LIG_LIR_Nem_3	1118	1124	PF02991	0.462
LIG_LIR_Nem_3	148	154	PF02991	0.550
LIG_LIR_Nem_3	516	521	PF02991	0.604
LIG_LIR_Nem_3	582	587	PF02991	0.647
LIG_LIR_Nem_3	757	761	PF02991	0.583
LIG_LIR_Nem_3	767	772	PF02991	0.543
LIG_LIR_Nem_3	777	782	PF02991	0.386
LIG_LIR_Nem_3	843	849	PF02991	0.599
LIG_LIR_Nem_3	880	884	PF02991	0.650
LIG_PCNA_PIPBox_1	561	570	PF02747	0.628
LIG_PCNA_yPIPBox_3	178	187	PF02747	0.529
LIG_Pex14_2	1124	1128	PF04695	0.441
LIG_Pex14_2	768	772	PF04695	0.489
LIG_RPA_C_Fungi	1022	1034	PF08784	0.498
LIG_SH2_CRK	846	850	PF00017	0.613
LIG_SH2_NCK_1	360	364	PF00017	0.645
LIG_SH2_NCK_1	531	535	PF00017	0.570
LIG_SH2_STAP1	360	364	PF00017	0.577
LIG_SH2_STAP1	728	732	PF00017	0.499
LIG_SH2_STAP1	881	885	PF00017	0.650
LIG_SH2_STAT3	485	488	PF00017	0.700
LIG_SH2_STAT3	86	89	PF00017	0.697
LIG_SH2_STAT5	728	731	PF00017	0.553
LIG_SH2_STAT5	835	838	PF00017	0.647
LIG_SH2_STAT5	903	906	PF00017	0.742
LIG_SH3_2	746	751	PF14604	0.548
LIG_SH3_3	421	427	PF00018	0.544
LIG_SH3_3	661	667	PF00018	0.663
LIG_SH3_3	743	749	PF00018	0.566
LIG_SH3_3	955	961	PF00018	0.620
LIG_Sin3_3	741	748	PF02671	0.558
LIG_SUMO_SIM_anti_2	416	422	PF11976	0.674
LIG_SUMO_SIM_anti_2	951	957	PF11976	0.608
LIG_SUMO_SIM_par_1	292	297	PF11976	0.380
LIG_TRAF2_1	487	490	PF00917	0.686
LIG_TRAF2_1	721	724	PF00917	0.545
LIG_TRAF2_1	895	898	PF00917	0.663
LIG_WW_1	367	370	PF00397	0.520
LIG_WW_3	425	429	PF00397	0.603
MOD_CDC14_SPxK_1	425	428	PF00782	0.671
MOD_CDK_SPK_2	27	32	PF00069	0.697
MOD_CDK_SPxK_1	340	346	PF00069	0.335
MOD_CDK_SPxK_1	422	428	PF00069	0.673
MOD_CDK_SPxxK_3	25	32	PF00069	0.700
MOD_CDK_SPxxK_3	706	713	PF00069	0.546
MOD_CK1_1	1075	1081	PF00069	0.602
MOD_CK1_1	1109	1115	PF00069	0.596
MOD_CK1_1	224	230	PF00069	0.256
MOD_CK1_1	25	31	PF00069	0.630
MOD_CK1_1	319	325	PF00069	0.346
MOD_CK1_1	327	333	PF00069	0.292
MOD_CK1_1	345	351	PF00069	0.217
MOD_CK1_1	410	416	PF00069	0.677
MOD_CK1_1	438	444	PF00069	0.676
MOD_CK1_1	450	456	PF00069	0.591
MOD_CK1_1	462	468	PF00069	0.563
MOD_CK1_1	537	543	PF00069	0.679
MOD_CK1_1	588	594	PF00069	0.655
MOD_CK1_1	602	608	PF00069	0.486
MOD_CK1_1	636	642	PF00069	0.683
MOD_CK1_1	804	810	PF00069	0.672
MOD_CK1_1	907	913	PF00069	0.455
MOD_CK1_1	933	939	PF00069	0.677
MOD_CK1_1	940	946	PF00069	0.616
MOD_CK2_1	1019	1025	PF00069	0.644
MOD_CK2_1	156	162	PF00069	0.380
MOD_CK2_1	327	333	PF00069	0.380
MOD_CK2_1	334	340	PF00069	0.317
MOD_CK2_1	484	490	PF00069	0.693
MOD_CK2_1	537	543	PF00069	0.633
MOD_CK2_1	733	739	PF00069	0.532
MOD_CK2_1	892	898	PF00069	0.677
MOD_CK2_1	957	963	PF00069	0.626
MOD_Cter_Amidation	652	655	PF01082	0.618
MOD_GlcNHglycan	1057	1060	PF01048	0.669
MOD_GlcNHglycan	1074	1077	PF01048	0.498
MOD_GlcNHglycan	190	195	PF01048	0.452
MOD_GlcNHglycan	228	231	PF01048	0.323
MOD_GlcNHglycan	318	321	PF01048	0.485
MOD_GlcNHglycan	326	329	PF01048	0.364
MOD_GlcNHglycan	396	399	PF01048	0.639
MOD_GlcNHglycan	402	405	PF01048	0.601
MOD_GlcNHglycan	412	415	PF01048	0.585
MOD_GlcNHglycan	449	452	PF01048	0.701
MOD_GlcNHglycan	482	485	PF01048	0.634
MOD_GlcNHglycan	535	539	PF01048	0.645
MOD_GlcNHglycan	555	558	PF01048	0.449
MOD_GlcNHglycan	589	593	PF01048	0.691
MOD_GlcNHglycan	601	604	PF01048	0.621
MOD_GlcNHglycan	675	678	PF01048	0.654
MOD_GlcNHglycan	679	682	PF01048	0.633
MOD_GlcNHglycan	694	698	PF01048	0.450
MOD_GlcNHglycan	730	733	PF01048	0.502
MOD_GlcNHglycan	784	787	PF01048	0.586
MOD_GlcNHglycan	836	839	PF01048	0.610
MOD_GlcNHglycan	910	913	PF01048	0.599
MOD_GlcNHglycan	932	935	PF01048	0.648
MOD_GlcNHglycan	940	943	PF01048	0.583
MOD_GSK3_1	1106	1113	PF00069	0.512
MOD_GSK3_1	122	129	PF00069	0.537
MOD_GSK3_1	135	142	PF00069	0.413
MOD_GSK3_1	162	169	PF00069	0.342
MOD_GSK3_1	172	179	PF00069	0.290
MOD_GSK3_1	21	28	PF00069	0.690
MOD_GSK3_1	217	224	PF00069	0.380
MOD_GSK3_1	246	253	PF00069	0.339
MOD_GSK3_1	308	315	PF00069	0.364
MOD_GSK3_1	334	341	PF00069	0.272
MOD_GSK3_1	345	352	PF00069	0.272
MOD_GSK3_1	381	388	PF00069	0.681
MOD_GSK3_1	459	466	PF00069	0.670
MOD_GSK3_1	480	487	PF00069	0.648
MOD_GSK3_1	633	640	PF00069	0.615
MOD_GSK3_1	673	680	PF00069	0.680
MOD_GSK3_1	70	77	PF00069	0.692
MOD_GSK3_1	770	777	PF00069	0.546
MOD_GSK3_1	812	819	PF00069	0.572
MOD_GSK3_1	904	911	PF00069	0.523
MOD_GSK3_1	926	933	PF00069	0.633
MOD_GSK3_1	934	941	PF00069	0.603
MOD_N-GLC_1	14	19	PF02516	0.627
MOD_N-GLC_1	144	149	PF02516	0.534
MOD_N-GLC_1	25	30	PF02516	0.670
MOD_N-GLC_1	447	452	PF02516	0.681
MOD_N-GLC_1	706	711	PF02516	0.556
MOD_N-GLC_1	892	897	PF02516	0.631
MOD_NEK2_1	1122	1127	PF00069	0.561
MOD_NEK2_1	255	260	PF00069	0.380
MOD_NEK2_1	613	618	PF00069	0.628
MOD_NEK2_1	693	698	PF00069	0.613
MOD_NEK2_1	726	731	PF00069	0.553
MOD_NEK2_1	772	777	PF00069	0.569
MOD_NEK2_1	782	787	PF00069	0.486
MOD_NEK2_1	790	795	PF00069	0.502
MOD_NEK2_1	8	13	PF00069	0.582
MOD_NEK2_2	1019	1024	PF00069	0.582
MOD_NEK2_2	435	440	PF00069	0.688
MOD_NEK2_2	44	49	PF00069	0.638
MOD_PIKK_1	1007	1013	PF00454	0.627
MOD_PIKK_1	253	259	PF00454	0.380
MOD_PIKK_1	334	340	PF00454	0.324
MOD_PIKK_1	345	351	PF00454	0.336
MOD_PIKK_1	407	413	PF00454	0.681
MOD_PIKK_1	484	490	PF00454	0.693
MOD_PIKK_1	569	575	PF00454	0.665
MOD_PIKK_1	613	619	PF00454	0.628
MOD_PIKK_1	726	732	PF00454	0.555
MOD_PIKK_1	74	80	PF00454	0.693
MOD_PIKK_1	762	768	PF00454	0.602
MOD_PK_1	221	227	PF00069	0.380
MOD_PKA_1	316	322	PF00069	0.278
MOD_PKA_2	1047	1053	PF00069	0.576
MOD_PKA_2	1095	1101	PF00069	0.476
MOD_PKA_2	316	322	PF00069	0.299
MOD_PKA_2	345	351	PF00069	0.339
MOD_PKA_2	385	391	PF00069	0.664
MOD_PKA_2	394	400	PF00069	0.593
MOD_PKA_2	407	413	PF00069	0.593
MOD_PKA_2	435	441	PF00069	0.685
MOD_PKA_2	457	463	PF00069	0.645
MOD_PKA_2	633	639	PF00069	0.685
MOD_PKA_2	782	788	PF00069	0.583
MOD_PKA_2	8	14	PF00069	0.647
MOD_PKA_2	938	944	PF00069	0.681
MOD_PKB_1	1044	1052	PF00069	0.659
MOD_PKB_1	96	104	PF00069	0.590
MOD_Plk_1	1062	1068	PF00069	0.594
MOD_Plk_1	139	145	PF00069	0.544
MOD_Plk_1	172	178	PF00069	0.380
MOD_Plk_1	296	302	PF00069	0.417
MOD_Plk_1	655	661	PF00069	0.676
MOD_Plk_1	693	699	PF00069	0.615
MOD_Plk_1	842	848	PF00069	0.572
MOD_Plk_1	898	904	PF00069	0.658
MOD_Plk_1	962	968	PF00069	0.628
MOD_Plk_2-3	892	898	PF00069	0.677
MOD_Plk_4	156	162	PF00069	0.411
MOD_Plk_4	296	302	PF00069	0.417
MOD_Plk_4	371	377	PF00069	0.530
MOD_Plk_4	54	60	PF00069	0.669
MOD_Plk_4	754	760	PF00069	0.594
MOD_Plk_4	804	810	PF00069	0.672
MOD_ProDKin_1	1085	1091	PF00069	0.653
MOD_ProDKin_1	1115	1121	PF00069	0.531
MOD_ProDKin_1	16	22	PF00069	0.691
MOD_ProDKin_1	25	31	PF00069	0.612
MOD_ProDKin_1	322	328	PF00069	0.335
MOD_ProDKin_1	340	346	PF00069	0.213
MOD_ProDKin_1	422	428	PF00069	0.673
MOD_ProDKin_1	637	643	PF00069	0.667
MOD_ProDKin_1	663	669	PF00069	0.660
MOD_ProDKin_1	70	76	PF00069	0.691
MOD_ProDKin_1	706	712	PF00069	0.548
MOD_ProDKin_1	957	963	PF00069	0.626
MOD_SUMO_rev_2	244	251	PF00179	0.380
TRG_DiLeu_BaEn_1	127	132	PF01217	0.512
TRG_DiLeu_BaEn_1	550	555	PF01217	0.659
TRG_DiLeu_BaEn_1	688	693	PF01217	0.649
TRG_DiLeu_BaEn_1	739	744	PF01217	0.539
TRG_DiLeu_BaLyEn_6	182	187	PF01217	0.380
TRG_DiLeu_BaLyEn_6	414	419	PF01217	0.675
TRG_DiLeu_BaLyEn_6	687	692	PF01217	0.529
TRG_DiLeu_BaLyEn_6	912	917	PF01217	0.544
TRG_ENDOCYTIC_2	151	154	PF00928	0.380
TRG_ENDOCYTIC_2	298	301	PF00928	0.483
TRG_ENDOCYTIC_2	360	363	PF00928	0.647
TRG_ENDOCYTIC_2	369	372	PF00928	0.573
TRG_ENDOCYTIC_2	758	761	PF00928	0.557
TRG_ENDOCYTIC_2	846	849	PF00928	0.615
TRG_ENDOCYTIC_2	884	887	PF00928	0.650
TRG_ER_diArg_1	1043	1046	PF00400	0.620
TRG_ER_diArg_1	316	318	PF00400	0.278
TRG_ER_diArg_1	36	38	PF00400	0.705
TRG_ER_diArg_1	552	554	PF00400	0.661
TRG_ER_diArg_1	6	9	PF00400	0.695
TRG_ER_diArg_1	93	96	PF00400	0.669
TRG_ER_diArg_1	983	986	PF00400	0.382
TRG_NES_CRM1_1	429	442	PF08389	0.639
TRG_NLS_MonoExtC_3	650	655	PF00514	0.657
TRG_NLS_MonoExtN_4	648	655	PF00514	0.636
TRG_Pf-PMV_PEXEL_1	185	190	PF00026	0.380
TRG_Pf-PMV_PEXEL_1	236	241	PF00026	0.357
TRG_Pf-PMV_PEXEL_1	690	694	PF00026	0.520
TRG_Pf-PMV_PEXEL_1	915	919	PF00026	0.538
TRG_Pf-PMV_PEXEL_1	976	981	PF00026	0.426

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WPG6	Leishmania donovani	99%	100%
A4H4L3	Leishmania braziliensis	80%	99%
E9AKS6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	99%
Q4QJ31	Leishmania major	90%	100%