LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania infantum
UniProt:
A4HSM7_LEIIN
TriTrypDb:
LINF_050015850
Length:
443

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HSM7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HSM7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 250 254 PF00656 0.667
CLV_C14_Caspase3-7 94 98 PF00656 0.683
CLV_NRD_NRD_1 139 141 PF00675 0.550
CLV_NRD_NRD_1 155 157 PF00675 0.567
CLV_NRD_NRD_1 291 293 PF00675 0.503
CLV_NRD_NRD_1 355 357 PF00675 0.561
CLV_NRD_NRD_1 362 364 PF00675 0.590
CLV_NRD_NRD_1 426 428 PF00675 0.544
CLV_PCSK_KEX2_1 138 140 PF00082 0.552
CLV_PCSK_KEX2_1 155 157 PF00082 0.567
CLV_PCSK_KEX2_1 290 292 PF00082 0.503
CLV_PCSK_KEX2_1 355 357 PF00082 0.561
CLV_PCSK_KEX2_1 362 364 PF00082 0.590
CLV_PCSK_KEX2_1 426 428 PF00082 0.544
CLV_PCSK_PC1ET2_1 138 140 PF00082 0.552
CLV_PCSK_PC1ET2_1 290 292 PF00082 0.529
CLV_PCSK_SKI1_1 11 15 PF00082 0.763
CLV_PCSK_SKI1_1 347 351 PF00082 0.539
CLV_PCSK_SKI1_1 372 376 PF00082 0.628
CLV_PCSK_SKI1_1 418 422 PF00082 0.569
CLV_PCSK_SKI1_1 74 78 PF00082 0.640
DEG_Nend_Nbox_1 1 3 PF02207 0.745
DOC_ANK_TNKS_1 328 335 PF00023 0.614
DOC_CYCLIN_RxL_1 74 84 PF00134 0.698
DOC_MAPK_MEF2A_6 96 105 PF00069 0.590
DOC_PP2B_LxvP_1 55 58 PF13499 0.730
DOC_PP2B_LxvP_1 7 10 PF13499 0.795
DOC_USP7_MATH_1 108 112 PF00917 0.717
DOC_USP7_MATH_1 214 218 PF00917 0.551
DOC_USP7_MATH_1 26 30 PF00917 0.655
DOC_USP7_MATH_1 332 336 PF00917 0.608
DOC_WW_Pin1_4 223 228 PF00397 0.675
LIG_14-3-3_CanoR_1 291 296 PF00244 0.586
LIG_14-3-3_CanoR_1 322 326 PF00244 0.506
LIG_14-3-3_CanoR_1 329 337 PF00244 0.506
LIG_14-3-3_CanoR_1 363 369 PF00244 0.561
LIG_14-3-3_CanoR_1 50 54 PF00244 0.820
LIG_Actin_WH2_2 409 425 PF00022 0.574
LIG_BIR_III_4 253 257 PF00653 0.688
LIG_deltaCOP1_diTrp_1 333 341 PF00928 0.505
LIG_FHA_1 100 106 PF00498 0.755
LIG_FHA_1 14 20 PF00498 0.628
LIG_FHA_1 2 8 PF00498 0.747
LIG_FHA_1 415 421 PF00498 0.573
LIG_FHA_1 50 56 PF00498 0.750
LIG_FHA_1 66 72 PF00498 0.527
LIG_FHA_2 116 122 PF00498 0.601
LIG_FHA_2 188 194 PF00498 0.535
LIG_FHA_2 245 251 PF00498 0.717
LIG_FHA_2 401 407 PF00498 0.692
LIG_LIR_Gen_1 111 120 PF02991 0.575
LIG_LIR_Gen_1 274 285 PF02991 0.609
LIG_LIR_Gen_1 294 304 PF02991 0.604
LIG_LIR_Nem_3 111 116 PF02991 0.535
LIG_LIR_Nem_3 274 280 PF02991 0.613
LIG_LIR_Nem_3 294 299 PF02991 0.602
LIG_LIR_Nem_3 431 435 PF02991 0.727
LIG_NRBOX 75 81 PF00104 0.697
LIG_PCNA_yPIPBox_3 123 136 PF02747 0.551
LIG_PCNA_yPIPBox_3 67 80 PF02747 0.622
LIG_SH2_GRB2like 203 206 PF00017 0.560
LIG_SH2_STAP1 192 196 PF00017 0.541
LIG_SH2_STAP1 277 281 PF00017 0.501
LIG_SH2_STAP1 296 300 PF00017 0.268
LIG_SH2_STAP1 326 330 PF00017 0.511
LIG_SH2_STAP1 353 357 PF00017 0.554
LIG_SH2_STAT3 269 272 PF00017 0.531
LIG_SH2_STAT5 269 272 PF00017 0.531
LIG_SH3_3 27 33 PF00018 0.740
LIG_SH3_3 51 57 PF00018 0.706
MOD_CDK_SPxK_1 223 229 PF00069 0.674
MOD_CK1_1 115 121 PF00069 0.542
MOD_CK1_1 385 391 PF00069 0.652
MOD_CK1_1 42 48 PF00069 0.743
MOD_CK2_1 108 114 PF00069 0.608
MOD_CK2_1 115 121 PF00069 0.568
MOD_CK2_1 187 193 PF00069 0.532
MOD_CK2_1 291 297 PF00069 0.529
MOD_CK2_1 433 439 PF00069 0.678
MOD_CK2_1 59 65 PF00069 0.680
MOD_GlcNHglycan 16 19 PF01048 0.752
MOD_GlcNHglycan 22 25 PF01048 0.685
MOD_GlcNHglycan 44 47 PF01048 0.746
MOD_GlcNHglycan 83 86 PF01048 0.690
MOD_GSK3_1 108 115 PF00069 0.578
MOD_GSK3_1 14 21 PF00069 0.811
MOD_GSK3_1 317 324 PF00069 0.564
MOD_GSK3_1 328 335 PF00069 0.481
MOD_GSK3_1 36 43 PF00069 0.752
MOD_GSK3_1 45 52 PF00069 0.774
MOD_N-GLC_1 40 45 PF02516 0.627
MOD_N-GLC_2 346 348 PF02516 0.542
MOD_NEK2_1 1 6 PF00069 0.747
MOD_NEK2_1 106 111 PF00069 0.721
MOD_NEK2_1 112 117 PF00069 0.573
MOD_NEK2_1 20 25 PF00069 0.529
MOD_NEK2_1 244 249 PF00069 0.613
MOD_NEK2_1 349 354 PF00069 0.646
MOD_NEK2_1 79 84 PF00069 0.706
MOD_NEK2_2 108 113 PF00069 0.609
MOD_PIKK_1 317 323 PF00454 0.537
MOD_PKA_1 291 297 PF00069 0.607
MOD_PKA_2 106 112 PF00069 0.633
MOD_PKA_2 187 193 PF00069 0.532
MOD_PKA_2 291 297 PF00069 0.595
MOD_PKA_2 321 327 PF00069 0.496
MOD_PKA_2 328 334 PF00069 0.529
MOD_PKA_2 49 55 PF00069 0.823
MOD_Plk_1 244 250 PF00069 0.639
MOD_Plk_1 26 32 PF00069 0.771
MOD_Plk_1 388 394 PF00069 0.703
MOD_Plk_1 39 45 PF00069 0.601
MOD_Plk_4 108 114 PF00069 0.608
MOD_Plk_4 291 297 PF00069 0.607
MOD_Plk_4 321 327 PF00069 0.501
MOD_Plk_4 332 338 PF00069 0.536
MOD_Plk_4 400 406 PF00069 0.623
MOD_ProDKin_1 223 229 PF00069 0.674
MOD_SUMO_rev_2 152 161 PF00179 0.557
TRG_DiLeu_BaEn_1 369 374 PF01217 0.442
TRG_DiLeu_BaEn_2 130 136 PF01217 0.639
TRG_ENDOCYTIC_2 277 280 PF00928 0.606
TRG_ENDOCYTIC_2 296 299 PF00928 0.271
TRG_ER_diArg_1 139 141 PF00400 0.532
TRG_ER_diArg_1 154 156 PF00400 0.592
TRG_ER_diArg_1 210 213 PF00400 0.692
TRG_ER_diArg_1 362 364 PF00400 0.590
TRG_ER_diArg_1 426 428 PF00400 0.544
TRG_NLS_MonoCore_2 289 294 PF00514 0.613
TRG_Pf-PMV_PEXEL_1 123 127 PF00026 0.568
TRG_Pf-PMV_PEXEL_1 74 78 PF00026 0.703

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3V2 Leptomonas seymouri 64% 100%
A0A3S5H5L5 Leishmania donovani 99% 100%
A4H4F0 Leishmania braziliensis 86% 100%
E9AKL1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%
Q4QJ97 Leishmania major 96% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS