LeishMANIAdb
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Vesicle transport protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Vesicle transport protein
Gene product:
Got1/Sft2-like family - putative
Species:
Leishmania infantum
UniProt:
A4HSK3_LEIIN
TriTrypDb:
LINF_050013300
Length:
163

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 12
NetGPI no yes: 0, no: 12
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 13
GO:0110165 cellular anatomical entity 1 13
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Expansion

Sequence features

A4HSK3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HSK3

Function

Biological processes
TermNameLevelCount
GO:0006810 transport 3 13
GO:0008104 protein localization 4 13
GO:0009987 cellular process 1 13
GO:0015031 protein transport 4 13
GO:0016192 vesicle-mediated transport 4 13
GO:0033036 macromolecule localization 2 13
GO:0045184 establishment of protein localization 3 13
GO:0051179 localization 1 13
GO:0051234 establishment of localization 2 13
GO:0051641 cellular localization 2 13
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Could not find GO molecular_function term for this entry.

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 20 24 PF00656 0.667
CLV_PCSK_SKI1_1 154 158 PF00082 0.366
CLV_PCSK_SKI1_1 90 94 PF00082 0.242
DEG_MDM2_SWIB_1 52 59 PF02201 0.279
DEG_Nend_UBRbox_2 1 3 PF02207 0.609
LIG_14-3-3_CanoR_1 100 109 PF00244 0.258
LIG_14-3-3_CanoR_1 90 96 PF00244 0.438
LIG_BRCT_BRCA1_1 30 34 PF00533 0.529
LIG_FHA_1 103 109 PF00498 0.266
LIG_FHA_1 3 9 PF00498 0.607
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P8A7 Leptomonas seymouri 35% 100%
A0A0N1I3M5 Leptomonas seymouri 43% 92%
A0A0N1I5N1 Leptomonas seymouri 64% 97%
A0A0S4JF33 Bodo saltans 36% 100%
A0A0S4JFY8 Bodo saltans 47% 100%
A0A1X0NLN3 Trypanosomatidae 49% 96%
A0A1X0P315 Trypanosomatidae 46% 96%
A0A1X0P7F6 Trypanosomatidae 32% 100%
A0A1X0P987 Trypanosomatidae 32% 78%
A0A3Q8IBK0 Leishmania donovani 34% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS