Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HSH1_LEIIN

TriTrypDb:

LINF_050009900

Length:

257

Annotations

LeishMANIAdb annotations

Probably not embedded into the membranes.

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HSH1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HSH1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	141	145	PF00656	0.253
CLV_NRD_NRD_1	201	203	PF00675	0.274
CLV_PCSK_KEX2_1	121	123	PF00082	0.491
CLV_PCSK_KEX2_1	201	203	PF00082	0.274
CLV_PCSK_PC1ET2_1	121	123	PF00082	0.491
CLV_PCSK_SKI1_1	100	104	PF00082	0.493
CLV_PCSK_SKI1_1	147	151	PF00082	0.459
CLV_PCSK_SKI1_1	153	157	PF00082	0.456
CLV_PCSK_SKI1_1	184	188	PF00082	0.199
CLV_PCSK_SKI1_1	202	206	PF00082	0.286
DEG_Nend_Nbox_1	1	3	PF02207	0.364
DEG_SPOP_SBC_1	37	41	PF00917	0.299
DOC_ANK_TNKS_1	139	146	PF00023	0.256
DOC_CYCLIN_RxL_1	24	34	PF00134	0.323
DOC_CYCLIN_yCln2_LP_2	98	104	PF00134	0.291
DOC_MAPK_MEF2A_6	100	108	PF00069	0.294
DOC_MAPK_MEF2A_6	130	138	PF00069	0.268
DOC_PP2B_LxvP_1	18	21	PF13499	0.344
DOC_PP4_FxxP_1	102	105	PF00568	0.291
DOC_USP7_MATH_1	35	39	PF00917	0.304
DOC_USP7_MATH_1	61	65	PF00917	0.384
DOC_WW_Pin1_4	2	7	PF00397	0.337
DOC_WW_Pin1_4	209	214	PF00397	0.495
DOC_WW_Pin1_4	251	256	PF00397	0.519
DOC_WW_Pin1_4	52	57	PF00397	0.353
LIG_14-3-3_CanoR_1	201	205	PF00244	0.480
LIG_14-3-3_CanoR_1	26	32	PF00244	0.321
LIG_Actin_WH2_2	212	230	PF00022	0.517
LIG_DLG_GKlike_1	29	36	PF00625	0.314
LIG_EH1_1	192	200	PF00400	0.199
LIG_FHA_1	101	107	PF00498	0.293
LIG_FHA_1	108	114	PF00498	0.308
LIG_FHA_1	133	139	PF00498	0.266
LIG_FHA_1	15	21	PF00498	0.349
LIG_FHA_1	185	191	PF00498	0.199
LIG_FHA_1	32	38	PF00498	0.309
LIG_FHA_1	48	54	PF00498	0.345
LIG_FHA_2	173	179	PF00498	0.266
LIG_LIR_Gen_1	173	183	PF02991	0.266
LIG_LIR_Nem_3	173	179	PF02991	0.266
LIG_LIR_Nem_3	203	208	PF02991	0.487
LIG_MYND_1	206	210	PF01753	0.499
LIG_Pex14_1	23	27	PF04695	0.334
LIG_REV1ctd_RIR_1	25	33	PF16727	0.323
LIG_SH2_SRC	142	145	PF00017	0.247
LIG_SH2_STAT5	142	145	PF00017	0.247
LIG_SH2_STAT5	163	166	PF00017	0.275
LIG_SH3_2	6	11	PF14604	0.334
LIG_SH3_3	207	213	PF00018	0.494
LIG_SH3_3	3	9	PF00018	0.330
LIG_SH3_3	50	56	PF00018	0.349
LIG_SH3_3	57	63	PF00018	0.371
MOD_CK1_1	38	44	PF00069	0.311
MOD_CK1_1	47	53	PF00069	0.340
MOD_CK1_1	87	93	PF00069	0.321
MOD_Cter_Amidation	199	202	PF01082	0.296
MOD_GlcNHglycan	165	168	PF01048	0.484
MOD_GlcNHglycan	68	71	PF01048	0.586
MOD_GSK3_1	200	207	PF00069	0.483
MOD_GSK3_1	27	34	PF00069	0.319
MOD_GSK3_1	52	59	PF00069	0.356
MOD_NEK2_1	27	32	PF00069	0.318
MOD_NEK2_1	36	41	PF00069	0.302
MOD_NEK2_2	200	205	PF00069	0.477
MOD_PKA_2	200	206	PF00069	0.480
MOD_Plk_1	132	138	PF00069	0.265
MOD_Plk_1	172	178	PF00069	0.270
MOD_Plk_1	87	93	PF00069	0.321
MOD_ProDKin_1	2	8	PF00069	0.335
MOD_ProDKin_1	209	215	PF00069	0.492
MOD_ProDKin_1	251	257	PF00069	0.524
MOD_ProDKin_1	52	58	PF00069	0.354
TRG_DiLeu_BaLyEn_6	8	13	PF01217	0.346