LeishMANIAdb
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Nucleolin_bd domain-containing protein

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Nucleolin_bd domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4HS97_LEIIN
TriTrypDb:
LINF_040015000
Length:
285

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

A4HS97
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HS97

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 98 102 PF00656 0.747
CLV_NRD_NRD_1 176 178 PF00675 0.557
CLV_NRD_NRD_1 242 244 PF00675 0.662
CLV_PCSK_FUR_1 223 227 PF00082 0.444
CLV_PCSK_KEX2_1 220 222 PF00082 0.394
CLV_PCSK_KEX2_1 225 227 PF00082 0.408
CLV_PCSK_KEX2_1 242 244 PF00082 0.594
CLV_PCSK_PC1ET2_1 220 222 PF00082 0.419
CLV_PCSK_PC1ET2_1 225 227 PF00082 0.384
CLV_PCSK_PC7_1 221 227 PF00082 0.376
CLV_PCSK_SKI1_1 147 151 PF00082 0.528
CLV_PCSK_SKI1_1 35 39 PF00082 0.539
CLV_PCSK_SKI1_1 70 74 PF00082 0.594
CLV_Separin_Metazoa 13 17 PF03568 0.502
DOC_MAPK_gen_1 220 230 PF00069 0.526
DOC_MAPK_gen_1 245 255 PF00069 0.571
DOC_MAPK_HePTP_8 7 19 PF00069 0.494
DOC_MAPK_MEF2A_6 10 19 PF00069 0.493
DOC_MAPK_MEF2A_6 197 204 PF00069 0.399
DOC_USP7_MATH_1 111 115 PF00917 0.657
DOC_USP7_MATH_1 157 161 PF00917 0.666
DOC_USP7_MATH_1 188 192 PF00917 0.557
DOC_USP7_MATH_1 259 263 PF00917 0.645
DOC_USP7_MATH_1 268 272 PF00917 0.658
DOC_USP7_MATH_1 51 55 PF00917 0.356
DOC_USP7_UBL2_3 216 220 PF12436 0.524
DOC_WW_Pin1_4 155 160 PF00397 0.522
DOC_WW_Pin1_4 264 269 PF00397 0.746
LIG_14-3-3_CanoR_1 177 182 PF00244 0.421
LIG_14-3-3_CanoR_1 276 281 PF00244 0.660
LIG_14-3-3_CanoR_1 53 57 PF00244 0.364
LIG_BIR_II_1 1 5 PF00653 0.530
LIG_Clathr_ClatBox_1 201 205 PF01394 0.404
LIG_eIF4E_1 195 201 PF01652 0.351
LIG_FHA_1 10 16 PF00498 0.370
LIG_FHA_2 185 191 PF00498 0.559
LIG_FHA_2 42 48 PF00498 0.497
LIG_LIR_Gen_1 198 204 PF02991 0.394
LIG_LIR_Nem_3 198 202 PF02991 0.453
LIG_NRBOX 10 16 PF00104 0.494
LIG_SH2_STAT5 195 198 PF00017 0.398
LIG_SH2_STAT5 199 202 PF00017 0.391
LIG_SH2_STAT5 49 52 PF00017 0.405
LIG_SH3_3 180 186 PF00018 0.546
LIG_SUMO_SIM_anti_2 227 232 PF11976 0.528
LIG_TRAF2_1 187 190 PF00917 0.565
LIG_TRAF2_1 81 84 PF00917 0.642
MOD_CK1_1 161 167 PF00069 0.489
MOD_CK1_1 264 270 PF00069 0.693
MOD_CK1_1 271 277 PF00069 0.610
MOD_CK1_1 52 58 PF00069 0.482
MOD_CK1_1 89 95 PF00069 0.712
MOD_CK2_1 111 117 PF00069 0.572
MOD_CK2_1 161 167 PF00069 0.518
MOD_CK2_1 184 190 PF00069 0.530
MOD_CK2_1 41 47 PF00069 0.492
MOD_GlcNHglycan 101 104 PF01048 0.561
MOD_GlcNHglycan 138 141 PF01048 0.600
MOD_GlcNHglycan 160 163 PF01048 0.689
MOD_GlcNHglycan 261 264 PF01048 0.697
MOD_GlcNHglycan 270 273 PF01048 0.743
MOD_GSK3_1 157 164 PF00069 0.612
MOD_GSK3_1 184 191 PF00069 0.558
MOD_GSK3_1 264 271 PF00069 0.672
MOD_LATS_1 182 188 PF00433 0.488
MOD_N-GLC_1 24 29 PF02516 0.557
MOD_N-GLC_1 89 94 PF02516 0.642
MOD_PIKK_1 261 267 PF00454 0.640
MOD_PKA_1 136 142 PF00069 0.700
MOD_PKA_1 177 183 PF00069 0.404
MOD_PKA_2 275 281 PF00069 0.558
MOD_PKA_2 52 58 PF00069 0.417
MOD_Plk_1 145 151 PF00069 0.525
MOD_Plk_1 188 194 PF00069 0.549
MOD_Plk_1 24 30 PF00069 0.538
MOD_Plk_2-3 109 115 PF00069 0.474
MOD_Plk_2-3 118 124 PF00069 0.719
MOD_Plk_2-3 94 100 PF00069 0.635
MOD_Plk_4 276 282 PF00069 0.687
MOD_Plk_4 52 58 PF00069 0.408
MOD_ProDKin_1 155 161 PF00069 0.517
MOD_ProDKin_1 264 270 PF00069 0.742
MOD_SUMO_for_1 224 227 PF00179 0.384
MOD_SUMO_rev_2 2 12 PF00179 0.397
TRG_ENDOCYTIC_2 199 202 PF00928 0.357
TRG_ER_diArg_1 242 245 PF00400 0.665
TRG_NES_CRM1_1 190 205 PF08389 0.407
TRG_NLS_MonoExtN_4 135 140 PF00514 0.722

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3R7MS09 Trypanosoma rangeli 37% 67%
A0A3S5H5E1 Leishmania donovani 99% 100%
A4H414 Leishmania braziliensis 67% 100%
E9AK81 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 100%
V5DEF7 Trypanosoma cruzi 37% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS