Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HS94_LEIIN

TriTrypDb:

LINF_040014700

Length:

488

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0035869	ciliary transition zone	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HS94

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HS94

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	315	319	PF00656	0.730
CLV_C14_Caspase3-7	380	384	PF00656	0.553
CLV_NRD_NRD_1	176	178	PF00675	0.726
CLV_NRD_NRD_1	27	29	PF00675	0.709
CLV_NRD_NRD_1	438	440	PF00675	0.740
CLV_NRD_NRD_1	486	488	PF00675	0.675
CLV_NRD_NRD_1	63	65	PF00675	0.780
CLV_PCSK_FUR_1	21	25	PF00082	0.842
CLV_PCSK_KEX2_1	176	178	PF00082	0.728
CLV_PCSK_KEX2_1	23	25	PF00082	0.839
CLV_PCSK_KEX2_1	27	29	PF00082	0.774
CLV_PCSK_KEX2_1	438	440	PF00082	0.740
CLV_PCSK_KEX2_1	486	488	PF00082	0.675
CLV_PCSK_KEX2_1	87	89	PF00082	0.840
CLV_PCSK_PC1ET2_1	23	25	PF00082	0.839
CLV_PCSK_PC1ET2_1	87	89	PF00082	0.782
CLV_PCSK_SKI1_1	176	180	PF00082	0.731
CLV_PCSK_SKI1_1	34	38	PF00082	0.787
CLV_PCSK_SKI1_1	358	362	PF00082	0.673
DEG_SCF_TRCP1_1	383	389	PF00400	0.682
DEG_SPOP_SBC_1	167	171	PF00917	0.702
DEG_SPOP_SBC_1	195	199	PF00917	0.838
DEG_SPOP_SBC_1	54	58	PF00917	0.831
DOC_CYCLIN_RxL_1	173	181	PF00134	0.726
DOC_MAPK_DCC_7	253	261	PF00069	0.713
DOC_MAPK_DCC_7	358	368	PF00069	0.654
DOC_MAPK_MEF2A_6	253	261	PF00069	0.713
DOC_MAPK_MEF2A_6	354	363	PF00069	0.695
DOC_PP2B_LxvP_1	120	123	PF13499	0.781
DOC_PP2B_PxIxI_1	256	262	PF00149	0.702
DOC_USP7_MATH_1	196	200	PF00917	0.762
DOC_USP7_MATH_1	209	213	PF00917	0.620
DOC_USP7_MATH_1	245	249	PF00917	0.523
DOC_USP7_MATH_1	292	296	PF00917	0.556
DOC_USP7_MATH_1	455	459	PF00917	0.485
DOC_USP7_MATH_1	54	58	PF00917	0.829
DOC_USP7_MATH_1	63	67	PF00917	0.732
DOC_WW_Pin1_4	113	118	PF00397	0.618
DOC_WW_Pin1_4	121	126	PF00397	0.674
DOC_WW_Pin1_4	152	157	PF00397	0.738
DOC_WW_Pin1_4	2	7	PF00397	0.757
DOC_WW_Pin1_4	251	256	PF00397	0.620
DOC_WW_Pin1_4	264	269	PF00397	0.672
DOC_WW_Pin1_4	36	41	PF00397	0.625
DOC_WW_Pin1_4	386	391	PF00397	0.689
DOC_WW_Pin1_4	59	64	PF00397	0.777
DOC_WW_Pin1_4	98	103	PF00397	0.823
LIG_14-3-3_CanoR_1	138	143	PF00244	0.739
LIG_14-3-3_CanoR_1	160	164	PF00244	0.791
LIG_14-3-3_CanoR_1	166	174	PF00244	0.753
LIG_14-3-3_CanoR_1	21	27	PF00244	0.765
LIG_14-3-3_CanoR_1	34	42	PF00244	0.597
LIG_14-3-3_CanoR_1	347	356	PF00244	0.729
LIG_14-3-3_CanoR_1	392	397	PF00244	0.486
LIG_14-3-3_CanoR_1	418	425	PF00244	0.619
LIG_14-3-3_CanoR_1	64	71	PF00244	0.761
LIG_Actin_WH2_2	417	434	PF00022	0.689
LIG_APCC_ABBA_1	417	422	PF00400	0.687
LIG_BRCT_BRCA1_1	154	158	PF00533	0.629
LIG_FHA_1	122	128	PF00498	0.852
LIG_FHA_1	169	175	PF00498	0.753
LIG_FHA_1	200	206	PF00498	0.635
LIG_FHA_1	256	262	PF00498	0.585
LIG_FHA_1	37	43	PF00498	0.632
LIG_FHA_1	99	105	PF00498	0.670
LIG_FHA_2	457	463	PF00498	0.642
LIG_LIR_Apic_2	263	268	PF02991	0.735
LIG_LIR_Apic_2	470	476	PF02991	0.713
LIG_PTAP_UEV_1	210	215	PF05743	0.652
LIG_SH2_CRK	265	269	PF00017	0.753
LIG_SH2_CRK	473	477	PF00017	0.656
LIG_SH2_STAT5	29	32	PF00017	0.691
LIG_SH2_STAT5	401	404	PF00017	0.672
LIG_SH3_3	120	126	PF00018	0.839
LIG_SH3_3	161	167	PF00018	0.780
LIG_SH3_3	201	207	PF00018	0.707
LIG_SH3_3	208	214	PF00018	0.622
LIG_SH3_3	384	390	PF00018	0.689
LIG_SH3_3	39	45	PF00018	0.821
LIG_SH3_3	413	419	PF00018	0.612
LIG_SH3_3	68	74	PF00018	0.825
LIG_TRAF2_1	340	343	PF00917	0.689
LIG_TRAF2_1	459	462	PF00917	0.523
LIG_TRFH_1	238	242	PF08558	0.806
LIG_TRFH_1	29	33	PF08558	0.647
MOD_CDC14_SPxK_1	389	392	PF00782	0.463
MOD_CDC14_SPxK_1	62	65	PF00782	0.780
MOD_CDK_SPK_2	59	64	PF00069	0.777
MOD_CDK_SPxK_1	386	392	PF00069	0.477
MOD_CDK_SPxK_1	59	65	PF00069	0.778
MOD_CK1_1	141	147	PF00069	0.816
MOD_CK1_1	152	158	PF00069	0.702
MOD_CK1_1	181	187	PF00069	0.782
MOD_CK1_1	197	203	PF00069	0.582
MOD_CK1_1	5	11	PF00069	0.804
MOD_CK1_1	98	104	PF00069	0.763
MOD_CK2_1	337	343	PF00069	0.736
MOD_CK2_1	392	398	PF00069	0.632
MOD_CK2_1	456	462	PF00069	0.529
MOD_GlcNHglycan	104	107	PF01048	0.831
MOD_GlcNHglycan	134	137	PF01048	0.836
MOD_GlcNHglycan	140	143	PF01048	0.727
MOD_GlcNHglycan	190	193	PF01048	0.741
MOD_GlcNHglycan	211	214	PF01048	0.658
MOD_GlcNHglycan	216	219	PF01048	0.639
MOD_GlcNHglycan	247	250	PF01048	0.531
MOD_GlcNHglycan	298	301	PF01048	0.686
MOD_GlcNHglycan	383	386	PF01048	0.671
MOD_GlcNHglycan	394	397	PF01048	0.599
MOD_GlcNHglycan	57	60	PF01048	0.696
MOD_GlcNHglycan	65	68	PF01048	0.716
MOD_GlcNHglycan	7	10	PF01048	0.700
MOD_GSK3_1	152	159	PF00069	0.718
MOD_GSK3_1	195	202	PF00069	0.748
MOD_GSK3_1	236	243	PF00069	0.791
MOD_GSK3_1	251	258	PF00069	0.498
MOD_GSK3_1	292	299	PF00069	0.722
MOD_GSK3_1	318	325	PF00069	0.760
MOD_GSK3_1	377	384	PF00069	0.640
MOD_GSK3_1	4	11	PF00069	0.745
MOD_GSK3_1	55	62	PF00069	0.827
MOD_GSK3_1	94	101	PF00069	0.732
MOD_NEK2_1	178	183	PF00069	0.727
MOD_NEK2_2	236	241	PF00069	0.777
MOD_PKA_1	87	93	PF00069	0.787
MOD_PKA_2	159	165	PF00069	0.738
MOD_PKA_2	181	187	PF00069	0.747
MOD_PKA_2	188	194	PF00069	0.670
MOD_PKA_2	240	246	PF00069	0.743
MOD_PKA_2	391	397	PF00069	0.477
MOD_PKA_2	63	69	PF00069	0.760
MOD_PKA_2	87	93	PF00069	0.787
MOD_Plk_2-3	318	324	PF00069	0.760
MOD_ProDKin_1	113	119	PF00069	0.620
MOD_ProDKin_1	121	127	PF00069	0.678
MOD_ProDKin_1	152	158	PF00069	0.739
MOD_ProDKin_1	2	8	PF00069	0.757
MOD_ProDKin_1	251	257	PF00069	0.618
MOD_ProDKin_1	264	270	PF00069	0.665
MOD_ProDKin_1	36	42	PF00069	0.628
MOD_ProDKin_1	386	392	PF00069	0.691
MOD_ProDKin_1	59	65	PF00069	0.778
MOD_ProDKin_1	98	104	PF00069	0.825
TRG_DiLeu_BaLyEn_6	174	179	PF01217	0.634
TRG_ENDOCYTIC_2	329	332	PF00928	0.764
TRG_ER_diArg_1	176	178	PF00400	0.763
TRG_ER_diArg_1	26	28	PF00400	0.717
TRG_ER_diArg_1	274	277	PF00400	0.658
TRG_ER_diArg_1	438	440	PF00400	0.740

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H5D8	Leishmania donovani	100%	93%
A4H411	Leishmania braziliensis	65%	100%
E9AK78	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	98%
Q9U1D2	Leishmania major	84%	100%