Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HS89_LEIIN

TriTrypDb:

LINF_040013800

Length:

174

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HS89

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HS89

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	54	56	PF00675	0.658
CLV_PCSK_KEX2_1	54	56	PF00082	0.658
CLV_PCSK_SKI1_1	137	141	PF00082	0.689
DEG_Kelch_Keap1_1	152	157	PF01344	0.675
DEG_Nend_UBRbox_1	1	4	PF02207	0.639
DEG_SPOP_SBC_1	12	16	PF00917	0.533
DOC_USP7_MATH_1	12	16	PF00917	0.571
DOC_USP7_MATH_1	72	76	PF00917	0.634
DOC_WW_Pin1_4	1	6	PF00397	0.637
DOC_WW_Pin1_4	32	37	PF00397	0.574
DOC_WW_Pin1_4	62	67	PF00397	0.604
LIG_14-3-3_CanoR_1	13	18	PF00244	0.520
LIG_14-3-3_CanoR_1	131	136	PF00244	0.651
LIG_14-3-3_CanoR_1	137	144	PF00244	0.628
LIG_BRCT_BRCA1_1	95	99	PF00533	0.626
LIG_EVH1_1	169	173	PF00568	0.507
LIG_FHA_1	12	18	PF00498	0.525
LIG_FHA_1	130	136	PF00498	0.665
LIG_FHA_1	138	144	PF00498	0.589
LIG_FHA_2	111	117	PF00498	0.586
LIG_FHA_2	136	142	PF00498	0.695
LIG_FHA_2	44	50	PF00498	0.656
LIG_IBAR_NPY_1	71	73	PF08397	0.577
LIG_LIR_Apic_2	80	86	PF02991	0.628
LIG_LIR_Nem_3	121	127	PF02991	0.688
LIG_MYND_1	8	12	PF01753	0.530
LIG_SH2_CRK	124	128	PF00017	0.555
LIG_SH2_CRK	28	32	PF00017	0.786
LIG_SH2_NCK_1	28	32	PF00017	0.652
LIG_SH2_STAP1	26	30	PF00017	0.583
LIG_SH2_STAT3	108	111	PF00017	0.533
LIG_SH2_STAT5	108	111	PF00017	0.533
LIG_SH2_STAT5	28	31	PF00017	0.496
LIG_SH3_1	2	8	PF00018	0.628
LIG_SH3_3	167	173	PF00018	0.669
LIG_SH3_3	2	8	PF00018	0.628
LIG_SUMO_SIM_par_1	126	134	PF11976	0.673
LIG_TYR_ITSM	120	127	PF00017	0.693
LIG_WW_2	170	173	PF00397	0.507
MOD_CK1_1	165	171	PF00069	0.654
MOD_CK1_1	75	81	PF00069	0.558
MOD_CK2_1	135	141	PF00069	0.681
MOD_CK2_1	43	49	PF00069	0.670
MOD_CK2_1	79	85	PF00069	0.627
MOD_GlcNHglycan	36	39	PF01048	0.694
MOD_GSK3_1	106	113	PF00069	0.632
MOD_GSK3_1	126	133	PF00069	0.386
MOD_GSK3_1	75	82	PF00069	0.651
MOD_GSK3_1	89	96	PF00069	0.613
MOD_LATS_1	11	17	PF00433	0.537
MOD_N-GLC_1	111	116	PF02516	0.593
MOD_NEK2_2	126	131	PF00069	0.504
MOD_PIKK_1	90	96	PF00454	0.617
MOD_PK_1	13	19	PF00069	0.518
MOD_PKA_2	12	18	PF00069	0.525
MOD_PKA_2	130	136	PF00069	0.624
MOD_Plk_1	165	171	PF00069	0.671
MOD_ProDKin_1	1	7	PF00069	0.634
MOD_ProDKin_1	32	38	PF00069	0.575
MOD_ProDKin_1	62	68	PF00069	0.603
TRG_DiLeu_BaLyEn_6	5	10	PF01217	0.552
TRG_ENDOCYTIC_2	124	127	PF00928	0.690
TRG_Pf-PMV_PEXEL_1	137	141	PF00026	0.554

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WNW2	Leishmania donovani	98%	100%
A4H3Z8	Leishmania braziliensis	61%	100%
O97006	Leishmania major	81%	100%