DUF1168-domain-containing protein

Quick info Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HS56_LEIIN

TriTrypDb:

LINF_040011100

Length:

167

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Phosphorylation

Amastigote: 54

Expansion

Sequence features

A4HS56

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HS56

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	133	137	PF00656	0.560
CLV_C14_Caspase3-7	156	160	PF00656	0.615
CLV_NRD_NRD_1	115	117	PF00675	0.588
CLV_NRD_NRD_1	94	96	PF00675	0.627
CLV_PCSK_FUR_1	113	117	PF00082	0.575
CLV_PCSK_KEX2_1	112	114	PF00082	0.601
CLV_PCSK_KEX2_1	115	117	PF00082	0.558
CLV_PCSK_KEX2_1	94	96	PF00082	0.625
CLV_PCSK_PC1ET2_1	112	114	PF00082	0.571
CLV_PCSK_SKI1_1	116	120	PF00082	0.564
DEG_SPOP_SBC_1	147	151	PF00917	0.651
DOC_CDC14_PxL_1	46	54	PF14671	0.617
DOC_CKS1_1	19	24	PF01111	0.715
DOC_USP7_MATH_1	147	151	PF00917	0.778
DOC_USP7_MATH_1	152	156	PF00917	0.713
DOC_USP7_UBL2_3	119	123	PF12436	0.581
DOC_WW_Pin1_4	18	23	PF00397	0.711
LIG_14-3-3_CanoR_1	41	47	PF00244	0.690
LIG_Actin_WH2_2	39	55	PF00022	0.596
LIG_APCC_ABBAyCdc20_2	94	100	PF00400	0.533
LIG_BIR_II_1	1	5	PF00653	0.649
LIG_CaM_IQ_9	105	121	PF13499	0.530
LIG_FHA_2	101	107	PF00498	0.429
LIG_FHA_2	19	25	PF00498	0.614
LIG_MYND_1	18	22	PF01753	0.625
LIG_PDZ_Class_3	162	167	PF00595	0.649
LIG_SH2_STAT5	39	42	PF00017	0.559
LIG_SH3_3	13	19	PF00018	0.754
LIG_TRAF2_1	21	24	PF00917	0.614
MOD_CDK_SPxxK_3	18	25	PF00069	0.618
MOD_CK1_1	139	145	PF00069	0.743
MOD_CK1_1	146	152	PF00069	0.714
MOD_CK1_1	153	159	PF00069	0.616
MOD_CK1_1	2	8	PF00069	0.717
MOD_CK1_1	42	48	PF00069	0.437
MOD_CK2_1	100	106	PF00069	0.432
MOD_CK2_1	18	24	PF00069	0.622
MOD_GlcNHglycan	144	148	PF01048	0.749
MOD_GlcNHglycan	150	153	PF01048	0.645
MOD_GlcNHglycan	6	9	PF01048	0.782
MOD_GSK3_1	100	107	PF00069	0.430
MOD_GSK3_1	130	137	PF00069	0.580
MOD_GSK3_1	139	146	PF00069	0.623
MOD_GSK3_1	148	155	PF00069	0.670
MOD_GSK3_1	35	42	PF00069	0.498
MOD_GSK3_1	60	67	PF00069	0.616
MOD_NEK2_1	1	6	PF00069	0.654
MOD_NEK2_1	148	153	PF00069	0.789
MOD_NEK2_1	52	57	PF00069	0.653
MOD_PK_1	104	110	PF00069	0.524
MOD_PKA_1	111	117	PF00069	0.439
MOD_PKA_2	157	163	PF00069	0.623
MOD_PKA_2	52	58	PF00069	0.683
MOD_PKB_1	132	140	PF00069	0.549
MOD_Plk_4	35	41	PF00069	0.633
MOD_ProDKin_1	18	24	PF00069	0.707
TRG_ER_diArg_1	113	116	PF00400	0.577
TRG_ER_diArg_1	131	134	PF00400	0.516
TRG_ER_diArg_1	50	53	PF00400	0.653
TRG_NLS_Bipartite_1	94	116	PF00514	0.567
TRG_NLS_MonoExtC_3	110	115	PF00514	0.571
TRG_NLS_MonoExtC_3	118	123	PF00514	0.468
TRG_NLS_MonoExtN_4	111	116	PF00514	0.575
TRG_NLS_MonoExtN_4	119	126	PF00514	0.408

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WNR8	Leishmania donovani	99%	100%
A4H443	Leishmania braziliensis	84%	100%
E9AK43	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
Q9NEE1	Leishmania major	91%	100%