LeishMANIAdb
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Mitochondrial ribosomal protein L47

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Mitochondrial ribosomal protein L47
Gene product:
Mitochondrial 39-S ribosomal protein L47 (MRP-L47) - putative
Species:
Leishmania infantum
UniProt:
A4HS22_LEIIN
TriTrypDb:
LINF_040007800
Length:
480

Annotations

Annotations by Jardim et al.

Ribosomal Protein, Mitochondrial 39-S ribosomal L47

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0000313 organellar ribosome 6 11
GO:0005761 mitochondrial ribosome 7 11
GO:0005840 ribosome 5 11
GO:0043226 organelle 2 11
GO:0043228 non-membrane-bounded organelle 3 11
GO:0043229 intracellular organelle 3 11
GO:0043232 intracellular non-membrane-bounded organelle 4 11
GO:0110165 cellular anatomical entity 1 12
GO:0000315 organellar large ribosomal subunit 5 1
GO:0005737 cytoplasm 2 1
GO:0005762 mitochondrial large ribosomal subunit 3 1
GO:0015934 large ribosomal subunit 4 1
GO:0031974 membrane-enclosed lumen 2 1
GO:0031981 nuclear lumen 5 1
GO:0032838 plasma membrane bounded cell projection cytoplasm 4 1
GO:0032991 protein-containing complex 1 1
GO:0043233 organelle lumen 3 1
GO:0044391 ribosomal subunit 3 1
GO:0070013 intracellular organelle lumen 4 1
GO:0097014 ciliary plasm 5 1
GO:0098798 mitochondrial protein-containing complex 2 1
GO:0099568 cytoplasmic region 3 1
GO:1990904 ribonucleoprotein complex 2 1

Expansion

Sequence features

A4HS22
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HS22

PDB structure(s): 7aih_R , 7am2_R , 7ane_R

Function

Biological processes
Term Name Level Count
GO:0006412 translation 4 12
GO:0006518 peptide metabolic process 4 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009058 biosynthetic process 2 12
GO:0009059 macromolecule biosynthetic process 4 12
GO:0009987 cellular process 1 12
GO:0019538 protein metabolic process 3 12
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0034645 obsolete cellular macromolecule biosynthetic process 4 12
GO:0043043 peptide biosynthetic process 5 12
GO:0043170 macromolecule metabolic process 3 12
GO:0043603 amide metabolic process 3 12
GO:0043604 amide biosynthetic process 4 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0044249 cellular biosynthetic process 3 12
GO:0044260 obsolete cellular macromolecule metabolic process 3 12
GO:0044271 cellular nitrogen compound biosynthetic process 4 12
GO:0071704 organic substance metabolic process 2 12
GO:1901564 organonitrogen compound metabolic process 3 12
GO:1901566 organonitrogen compound biosynthetic process 4 12
GO:1901576 organic substance biosynthetic process 3 12
GO:0032543 mitochondrial translation 5 1
Molecular functions
Term Name Level Count
GO:0003735 structural constituent of ribosome 2 12
GO:0005198 structural molecule activity 1 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 15 19 PF00656 0.333
CLV_C14_Caspase3-7 337 341 PF00656 0.422
CLV_C14_Caspase3-7 351 355 PF00656 0.391
CLV_NRD_NRD_1 147 149 PF00675 0.440
CLV_NRD_NRD_1 199 201 PF00675 0.574
CLV_NRD_NRD_1 384 386 PF00675 0.455
CLV_NRD_NRD_1 40 42 PF00675 0.420
CLV_NRD_NRD_1 6 8 PF00675 0.539
CLV_PCSK_KEX2_1 147 149 PF00082 0.440
CLV_PCSK_KEX2_1 185 187 PF00082 0.514
CLV_PCSK_KEX2_1 199 201 PF00082 0.416
CLV_PCSK_KEX2_1 25 27 PF00082 0.179
CLV_PCSK_KEX2_1 384 386 PF00082 0.505
CLV_PCSK_KEX2_1 40 42 PF00082 0.297
CLV_PCSK_KEX2_1 465 467 PF00082 0.580
CLV_PCSK_KEX2_1 6 8 PF00082 0.539
CLV_PCSK_PC1ET2_1 185 187 PF00082 0.553
CLV_PCSK_PC1ET2_1 25 27 PF00082 0.313
CLV_PCSK_PC1ET2_1 465 467 PF00082 0.580
CLV_PCSK_PC7_1 2 8 PF00082 0.580
CLV_PCSK_SKI1_1 111 115 PF00082 0.405
CLV_PCSK_SKI1_1 116 120 PF00082 0.239
CLV_PCSK_SKI1_1 142 146 PF00082 0.522
CLV_PCSK_SKI1_1 155 159 PF00082 0.403
CLV_PCSK_SKI1_1 288 292 PF00082 0.514
CLV_PCSK_SKI1_1 431 435 PF00082 0.391
CLV_PCSK_SKI1_1 466 470 PF00082 0.580
CLV_PCSK_SKI1_1 58 62 PF00082 0.297
CLV_PCSK_SKI1_1 96 100 PF00082 0.342
DEG_APCC_DBOX_1 276 284 PF00400 0.592
DEG_APCC_DBOX_1 40 48 PF00400 0.411
DEG_APCC_DBOX_1 57 65 PF00400 0.208
DEG_Nend_UBRbox_1 1 4 PF02207 0.657
DEG_SIAH_1 370 378 PF03145 0.435
DEG_SPOP_SBC_1 209 213 PF00917 0.615
DOC_CYCLIN_RxL_1 152 162 PF00134 0.422
DOC_MAPK_MEF2A_6 168 175 PF00069 0.385
DOC_MAPK_RevD_3 171 186 PF00069 0.425
DOC_PP2B_LxvP_1 264 267 PF13499 0.568
DOC_PP2B_PxIxI_1 301 307 PF00149 0.335
DOC_SPAK_OSR1_1 160 164 PF12202 0.542
DOC_USP7_MATH_1 209 213 PF00917 0.666
DOC_USP7_MATH_1 242 246 PF00917 0.724
DOC_USP7_MATH_1 35 39 PF00917 0.299
DOC_USP7_MATH_1 79 83 PF00917 0.297
DOC_USP7_UBL2_3 95 99 PF12436 0.333
DOC_WW_Pin1_4 440 445 PF00397 0.544
LIG_14-3-3_CanoR_1 2 10 PF00244 0.630
LIG_14-3-3_CanoR_1 333 337 PF00244 0.496
LIG_14-3-3_CanoR_1 40 45 PF00244 0.315
LIG_14-3-3_CanoR_1 466 475 PF00244 0.533
LIG_14-3-3_CanoR_1 58 68 PF00244 0.410
LIG_Actin_WH2_2 71 87 PF00022 0.313
LIG_APCC_ABBA_1 110 115 PF00400 0.432
LIG_DLG_GKlike_1 40 47 PF00625 0.313
LIG_EVH1_1 264 268 PF00568 0.607
LIG_FHA_1 136 142 PF00498 0.432
LIG_FHA_1 172 178 PF00498 0.579
LIG_FHA_1 467 473 PF00498 0.577
LIG_FHA_2 223 229 PF00498 0.519
LIG_FHA_2 310 316 PF00498 0.498
LIG_FHA_2 349 355 PF00498 0.468
LIG_FHA_2 61 67 PF00498 0.433
LIG_LIR_Apic_2 203 209 PF02991 0.555
LIG_LIR_Apic_2 439 444 PF02991 0.415
LIG_LIR_Nem_3 189 195 PF02991 0.416
LIG_NRBOX 153 159 PF00104 0.496
LIG_PDZ_Class_1 475 480 PF00595 0.430
LIG_Pex14_1 402 406 PF04695 0.370
LIG_SH2_CRK 122 126 PF00017 0.459
LIG_SH2_CRK 422 426 PF00017 0.372
LIG_SH2_GRB2like 422 425 PF00017 0.377
LIG_SH2_NCK_1 372 376 PF00017 0.425
LIG_SH2_SRC 379 382 PF00017 0.465
LIG_SH2_STAP1 222 226 PF00017 0.579
LIG_SH2_STAP1 422 426 PF00017 0.386
LIG_SH2_STAT5 300 303 PF00017 0.460
LIG_SH2_STAT5 344 347 PF00017 0.454
LIG_SH2_STAT5 409 412 PF00017 0.389
LIG_SH2_STAT5 428 431 PF00017 0.287
LIG_SH2_STAT5 68 71 PF00017 0.316
LIG_SH3_1 122 128 PF00018 0.465
LIG_SH3_1 270 276 PF00018 0.542
LIG_SH3_2 265 270 PF14604 0.535
LIG_SH3_3 122 128 PF00018 0.465
LIG_SH3_3 24 30 PF00018 0.297
LIG_SH3_3 262 268 PF00018 0.483
LIG_SH3_3 270 276 PF00018 0.477
LIG_SH3_3 314 320 PF00018 0.446
LIG_SH3_3 394 400 PF00018 0.410
LIG_SUMO_SIM_par_1 169 174 PF11976 0.421
LIG_SUMO_SIM_par_1 357 363 PF11976 0.465
LIG_SUMO_SIM_par_1 442 448 PF11976 0.421
LIG_TRAF2_1 360 363 PF00917 0.525
LIG_TRAF2_1 388 391 PF00917 0.406
LIG_UBA3_1 60 65 PF00899 0.369
LIG_WW_3 274 278 PF00397 0.614
MOD_CK1_1 212 218 PF00069 0.542
MOD_CK1_1 289 295 PF00069 0.519
MOD_CK2_1 222 228 PF00069 0.522
MOD_CK2_1 238 244 PF00069 0.574
MOD_CK2_1 357 363 PF00069 0.541
MOD_CK2_1 436 442 PF00069 0.414
MOD_CK2_1 60 66 PF00069 0.297
MOD_GlcNHglycan 214 217 PF01048 0.584
MOD_GlcNHglycan 234 237 PF01048 0.507
MOD_GlcNHglycan 240 243 PF01048 0.700
MOD_GlcNHglycan 3 6 PF01048 0.610
MOD_GSK3_1 208 215 PF00069 0.528
MOD_GSK3_1 238 245 PF00069 0.676
MOD_GSK3_1 344 351 PF00069 0.443
MOD_GSK3_1 436 443 PF00069 0.502
MOD_N-GLC_1 302 307 PF02516 0.402
MOD_N-GLC_1 420 425 PF02516 0.374
MOD_NEK2_1 1 6 PF00069 0.595
MOD_NEK2_1 143 148 PF00069 0.538
MOD_NEK2_1 348 353 PF00069 0.416
MOD_NEK2_1 60 65 PF00069 0.297
MOD_NEK2_2 137 142 PF00069 0.484
MOD_NEK2_2 35 40 PF00069 0.309
MOD_PIKK_1 180 186 PF00454 0.548
MOD_PKA_1 40 46 PF00069 0.420
MOD_PKA_2 1 7 PF00069 0.659
MOD_PKA_2 237 243 PF00069 0.655
MOD_PKA_2 309 315 PF00069 0.496
MOD_PKA_2 332 338 PF00069 0.515
MOD_PKA_2 40 46 PF00069 0.420
MOD_Plk_1 222 228 PF00069 0.558
MOD_Plk_1 302 308 PF00069 0.333
MOD_Plk_1 389 395 PF00069 0.420
MOD_Plk_1 87 93 PF00069 0.389
MOD_Plk_2-3 217 223 PF00069 0.545
MOD_Plk_4 217 223 PF00069 0.528
MOD_Plk_4 389 395 PF00069 0.420
MOD_Plk_4 50 56 PF00069 0.433
MOD_ProDKin_1 440 446 PF00069 0.549
TRG_ENDOCYTIC_2 14 17 PF00928 0.311
TRG_ENDOCYTIC_2 372 375 PF00928 0.411
TRG_ENDOCYTIC_2 422 425 PF00928 0.377
TRG_ER_diArg_1 147 149 PF00400 0.440
TRG_ER_diArg_1 383 385 PF00400 0.448
TRG_ER_diArg_1 39 41 PF00400 0.418
TRG_NES_CRM1_1 152 165 PF08389 0.487
TRG_NES_CRM1_1 340 354 PF08389 0.530
TRG_NLS_MonoCore_2 461 466 PF00514 0.561
TRG_NLS_MonoExtC_3 461 466 PF00514 0.561

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PA99 Leptomonas seymouri 79% 98%
A0A0S4IZC9 Bodo saltans 53% 99%
A0A1X0NLD2 Trypanosomatidae 63% 98%
A0A3S5H591 Leishmania donovani 100% 100%
A0A422NNG2 Trypanosoma rangeli 65% 97%
A4H3U7 Leishmania braziliensis 90% 100%
C9ZY15 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 65% 100%
E9AK09 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 100%
Q9XZY7 Leishmania major 97% 100%
V5B964 Trypanosoma cruzi 63% 98%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS