Surface antigen-like protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

surface antigen-like protein

Species:

Leishmania infantum

UniProt:

A4HS15_LEIIN

TriTrypDb:

LINF_040007100

Length:

182

Annotations

Annotations by Jardim et al.

Plasma membrane, Surface antigen-like

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 5, no: 0
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HS15

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HS15

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	4	8	PF00082	0.484
DEG_SPOP_SBC_1	90	94	PF00917	0.386
DOC_MAPK_MEF2A_6	162	170	PF00069	0.556
DOC_USP7_MATH_1	145	149	PF00917	0.466
DOC_USP7_MATH_1	153	157	PF00917	0.451
DOC_USP7_MATH_1	35	39	PF00917	0.585
DOC_USP7_MATH_1	79	83	PF00917	0.536
DOC_USP7_MATH_1	89	93	PF00917	0.370
DOC_WW_Pin1_4	100	105	PF00397	0.399
DOC_WW_Pin1_4	27	32	PF00397	0.594
LIG_14-3-3_CanoR_1	135	144	PF00244	0.419
LIG_14-3-3_CanoR_1	162	167	PF00244	0.561
LIG_14-3-3_CanoR_1	36	42	PF00244	0.595
LIG_BIR_II_1	1	5	PF00653	0.507
LIG_BRCT_BRCA1_1	66	70	PF00533	0.522
LIG_DLG_GKlike_1	162	170	PF00625	0.556
LIG_FHA_1	161	167	PF00498	0.493
LIG_FHA_1	71	77	PF00498	0.596
LIG_LIR_LC3C_4	163	168	PF02991	0.486
LIG_LIR_Nem_3	146	152	PF02991	0.572
LIG_PDZ_Class_1	177	182	PF00595	0.559
LIG_PTAP_UEV_1	30	35	PF05743	0.501
LIG_SH3_2	31	36	PF14604	0.559
LIG_SH3_3	28	34	PF00018	0.573
MOD_CK1_1	138	144	PF00069	0.446
MOD_CK1_1	23	29	PF00069	0.586
MOD_CK1_1	40	46	PF00069	0.610
MOD_CK1_1	49	55	PF00069	0.556
MOD_CK1_1	57	63	PF00069	0.527
MOD_GlcNHglycan	140	143	PF01048	0.429
MOD_GlcNHglycan	31	34	PF01048	0.582
MOD_GlcNHglycan	57	60	PF01048	0.634
MOD_GSK3_1	162	169	PF00069	0.553
MOD_GSK3_1	20	27	PF00069	0.574
MOD_GSK3_1	43	50	PF00069	0.689
MOD_GSK3_1	51	58	PF00069	0.600
MOD_GSK3_1	62	69	PF00069	0.627
MOD_GSK3_1	70	77	PF00069	0.597
MOD_GSK3_1	79	86	PF00069	0.381
MOD_N-GLC_1	54	59	PF02516	0.545
MOD_N-GLC_1	62	67	PF02516	0.553
MOD_N-GLC_2	97	99	PF02516	0.507
MOD_NEK2_1	161	166	PF00069	0.581
MOD_NEK2_1	174	179	PF00069	0.541
MOD_NEK2_1	70	75	PF00069	0.547
MOD_NEK2_2	145	150	PF00069	0.467
MOD_OFUCOSY	114	120	PF10250	0.505
MOD_PKA_2	161	167	PF00069	0.563
MOD_PKA_2	35	41	PF00069	0.621
MOD_Plk_1	23	29	PF00069	0.557
MOD_Plk_4	15	21	PF00069	0.461
MOD_Plk_4	162	168	PF00069	0.672
MOD_ProDKin_1	100	106	PF00069	0.397
MOD_ProDKin_1	27	33	PF00069	0.594

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H585	Leishmania donovani	99%	100%
A4H445	Leishmania braziliensis	36%	100%
E9AK02	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q9XZY0	Leishmania major	88%	100%