Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HS04_LEIIN

TriTrypDb:

LINF_040005900

Length:

158

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HS04

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HS04

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	36	40	PF00656	0.616
CLV_NRD_NRD_1	16	18	PF00675	0.485
CLV_NRD_NRD_1	2	4	PF00675	0.641
CLV_NRD_NRD_1	71	73	PF00675	0.504
CLV_PCSK_KEX2_1	16	18	PF00082	0.485
CLV_PCSK_KEX2_1	2	4	PF00082	0.641
CLV_PCSK_KEX2_1	71	73	PF00082	0.504
CLV_PCSK_SKI1_1	16	20	PF00082	0.470
CLV_PCSK_SKI1_1	3	7	PF00082	0.545
CLV_PCSK_SKI1_1	61	65	PF00082	0.493
DEG_APCC_DBOX_1	106	114	PF00400	0.495
DEG_APCC_DBOX_1	60	68	PF00400	0.502
DEG_APCC_DBOX_1	71	79	PF00400	0.391
DEG_Nend_UBRbox_1	1	4	PF02207	0.620
DEG_SCF_FBW7_2	75	80	PF00400	0.441
DEG_SPOP_SBC_1	46	50	PF00917	0.563
DOC_MAPK_MEF2A_6	61	69	PF00069	0.499
DOC_USP7_MATH_1	10	14	PF00917	0.553
DOC_USP7_MATH_1	137	141	PF00917	0.700
DOC_USP7_MATH_1	147	151	PF00917	0.563
DOC_WW_Pin1_4	3	8	PF00397	0.545
DOC_WW_Pin1_4	73	78	PF00397	0.433
LIG_14-3-3_CanoR_1	16	22	PF00244	0.705
LIG_FHA_1	74	80	PF00498	0.386
LIG_FHA_2	34	40	PF00498	0.610
LIG_FHA_2	54	60	PF00498	0.401
LIG_LIR_Nem_3	13	18	PF02991	0.579
LIG_LIR_Nem_3	57	63	PF02991	0.589
LIG_NRBOX	63	69	PF00104	0.497
LIG_PDZ_Class_2	153	158	PF00595	0.624
LIG_SH2_CRK	60	64	PF00017	0.580
LIG_SH3_3	126	132	PF00018	0.515
LIG_SH3_3	49	55	PF00018	0.608
MOD_CK1_1	41	47	PF00069	0.628
MOD_GlcNHglycan	44	47	PF01048	0.696
MOD_GlcNHglycan	8	11	PF01048	0.436
MOD_GSK3_1	38	45	PF00069	0.688
MOD_GSK3_1	6	13	PF00069	0.487
MOD_LATS_1	99	105	PF00433	0.495
MOD_N-GLC_1	27	32	PF02516	0.619
MOD_PKA_1	16	22	PF00069	0.617
MOD_PKA_1	71	77	PF00069	0.495
MOD_PKA_2	16	22	PF00069	0.680
MOD_PKA_2	71	77	PF00069	0.495
MOD_Plk_1	101	107	PF00069	0.617
MOD_Plk_1	120	126	PF00069	0.351
MOD_Plk_1	138	144	PF00069	0.572
MOD_Plk_2-3	102	108	PF00069	0.418
MOD_ProDKin_1	3	9	PF00069	0.544
MOD_ProDKin_1	73	79	PF00069	0.435
MOD_SUMO_rev_2	85	93	PF00179	0.505
TRG_DiLeu_BaEn_3	151	157	PF01217	0.542
TRG_ENDOCYTIC_2	60	63	PF00928	0.580
TRG_ER_diArg_1	1	3	PF00400	0.663
TRG_ER_diArg_1	122	125	PF00400	0.518
TRG_ER_diArg_1	15	17	PF00400	0.488
TRG_ER_diArg_1	70	72	PF00400	0.501
TRG_NES_CRM1_1	73	88	PF08389	0.450
TRG_Pf-PMV_PEXEL_1	111	115	PF00026	0.518
TRG_Pf-PMV_PEXEL_1	61	66	PF00026	0.502

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H575	Leishmania donovani	98%	100%
A4H3S9	Leishmania braziliensis	71%	97%
A4HE83	Leishmania braziliensis	60%	100%
E9AJZ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q9BLQ6	Leishmania major	90%	100%