LeishMANIAdb
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Putative folate/biopterin transporter

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Putative folate/biopterin transporter
Gene product:
pteridine transporter (truncated) - putative
Species:
Leishmania infantum
UniProt:
A4HRZ7_LEIIN
TriTrypDb:
LINF_040005100
Length:
295

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9
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Expansion

Sequence features

A4HRZ7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HRZ7

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_PCSK_SKI1_1 227 231 PF00082 0.434
DEG_SPOP_SBC_1 198 202 PF00917 0.435
DEG_SPOP_SBC_1 214 218 PF00917 0.347
DOC_CKS1_1 235 240 PF01111 0.389
DOC_CYCLIN_yCln2_LP_2 37 43 PF00134 0.389
DOC_MAPK_gen_1 261 268 PF00069 0.700
DOC_MAPK_gen_1 283 291 PF00069 0.710
DOC_MAPK_MEF2A_6 138 145 PF00069 0.340
DOC_MAPK_MEF2A_6 283 291 PF00069 0.568
DOC_PP2B_LxvP_1 37 40 PF13499 0.389
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P2H3 Leptomonas seymouri 49% 95%
A0A0N1I0I7 Leptomonas seymouri 87% 100%
A0A0N1IFX7 Leptomonas seymouri 50% 98%
A0A422MS51 Trypanosoma rangeli 48% 100%
A0A451EJU7 Leishmania donovani 99% 97%
V5BIG5 Trypanosoma cruzi 54% 100%
V5BIY0 Trypanosoma cruzi 57% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS