LeishMANIAdb
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Calcium-transporting ATPase

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Calcium-transporting ATPase
Gene product:
calcium-translocating P-type ATPase
Species:
Leishmania infantum
UniProt:
A4HRZ6_LEIIN
TriTrypDb:
LINF_040005000
Length:
1023

Annotations

LeishMANIAdb annotations

Homologous to animal ER-localized Ca2+ ATPases. Localization: ER (by homology)

Annotations by Jardim et al.

Transporters, Calcium-transporting ATPase

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0016020 membrane 2 12
GO:0110165 cellular anatomical entity 1 12
GO:0005783 endoplasmic reticulum 5 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

A4HRZ6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HRZ6

Function

Biological processes
Term Name Level Count
GO:0006810 transport 3 1
GO:0006811 monoatomic ion transport 4 1
GO:0006812 monoatomic cation transport 5 1
GO:0006816 calcium ion transport 7 1
GO:0006873 intracellular monoatomic ion homeostasis 4 1
GO:0006874 intracellular calcium ion homeostasis 7 1
GO:0006875 obsolete intracellular metal ion homeostasis 6 1
GO:0009987 cellular process 1 1
GO:0019725 cellular homeostasis 2 1
GO:0030001 metal ion transport 6 1
GO:0030003 intracellular monoatomic cation homeostasis 5 1
GO:0034220 monoatomic ion transmembrane transport 3 1
GO:0042592 homeostatic process 3 1
GO:0048878 chemical homeostasis 4 1
GO:0050801 monoatomic ion homeostasis 5 1
GO:0051179 localization 1 1
GO:0051234 establishment of localization 2 1
GO:0055065 obsolete metal ion homeostasis 7 1
GO:0055074 calcium ion homeostasis 8 1
GO:0055080 monoatomic cation homeostasis 6 1
GO:0055082 intracellular chemical homeostasis 3 1
GO:0055085 transmembrane transport 2 1
GO:0065007 biological regulation 1 1
GO:0065008 regulation of biological quality 2 1
GO:0070588 calcium ion transmembrane transport 6 1
GO:0072503 obsolete cellular divalent inorganic cation homeostasis 6 1
GO:0072507 obsolete divalent inorganic cation homeostasis 7 1
GO:0098655 monoatomic cation transmembrane transport 4 1
GO:0098660 inorganic ion transmembrane transport 4 1
GO:0098662 inorganic cation transmembrane transport 5 1
GO:0098771 inorganic ion homeostasis 6 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 12
GO:0003824 catalytic activity 1 12
GO:0005215 transporter activity 1 12
GO:0005388 P-type calcium transporter activity 4 12
GO:0005488 binding 1 12
GO:0005524 ATP binding 5 12
GO:0008324 monoatomic cation transmembrane transporter activity 4 12
GO:0015075 monoatomic ion transmembrane transporter activity 3 12
GO:0015085 calcium ion transmembrane transporter activity 6 12
GO:0015318 inorganic molecular entity transmembrane transporter activity 3 12
GO:0015399 primary active transmembrane transporter activity 4 12
GO:0015662 P-type ion transporter activity 4 12
GO:0016462 pyrophosphatase activity 5 12
GO:0016787 hydrolase activity 2 12
GO:0016817 hydrolase activity, acting on acid anhydrides 3 12
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 12
GO:0016887 ATP hydrolysis activity 7 12
GO:0017076 purine nucleotide binding 4 12
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 12
GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3 12
GO:0022804 active transmembrane transporter activity 3 12
GO:0022853 active monoatomic ion transmembrane transporter activity 4 12
GO:0022857 transmembrane transporter activity 2 12
GO:0022890 inorganic cation transmembrane transporter activity 4 12
GO:0030554 adenyl nucleotide binding 5 12
GO:0032553 ribonucleotide binding 3 12
GO:0032555 purine ribonucleotide binding 4 12
GO:0032559 adenyl ribonucleotide binding 5 12
GO:0035639 purine ribonucleoside triphosphate binding 4 12
GO:0036094 small molecule binding 2 12
GO:0042626 ATPase-coupled transmembrane transporter activity 2 12
GO:0043167 ion binding 2 12
GO:0043168 anion binding 3 12
GO:0046873 metal ion transmembrane transporter activity 5 12
GO:0097159 organic cyclic compound binding 2 12
GO:0097367 carbohydrate derivative binding 2 12
GO:0140358 P-type transmembrane transporter activity 3 12
GO:0140657 ATP-dependent activity 1 12
GO:1901265 nucleoside phosphate binding 3 12
GO:1901363 heterocyclic compound binding 2 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 608 612 PF00656 0.442
CLV_NRD_NRD_1 329 331 PF00675 0.228
CLV_NRD_NRD_1 495 497 PF00675 0.264
CLV_NRD_NRD_1 639 641 PF00675 0.239
CLV_NRD_NRD_1 667 669 PF00675 0.240
CLV_NRD_NRD_1 823 825 PF00675 0.254
CLV_PCSK_KEX2_1 37 39 PF00082 0.265
CLV_PCSK_KEX2_1 480 482 PF00082 0.279
CLV_PCSK_KEX2_1 525 527 PF00082 0.238
CLV_PCSK_KEX2_1 639 641 PF00082 0.318
CLV_PCSK_KEX2_1 667 669 PF00082 0.213
CLV_PCSK_KEX2_1 823 825 PF00082 0.238
CLV_PCSK_PC1ET2_1 37 39 PF00082 0.253
CLV_PCSK_PC1ET2_1 480 482 PF00082 0.279
CLV_PCSK_PC1ET2_1 525 527 PF00082 0.318
CLV_PCSK_SKI1_1 165 169 PF00082 0.318
CLV_PCSK_SKI1_1 3 7 PF00082 0.370
CLV_PCSK_SKI1_1 477 481 PF00082 0.258
CLV_PCSK_SKI1_1 486 490 PF00082 0.211
CLV_PCSK_SKI1_1 529 533 PF00082 0.291
CLV_PCSK_SKI1_1 69 73 PF00082 0.323
CLV_PCSK_SKI1_1 733 737 PF00082 0.266
CLV_PCSK_SKI1_1 752 756 PF00082 0.251
CLV_PCSK_SKI1_1 981 985 PF00082 0.338
DOC_ANK_TNKS_1 462 469 PF00023 0.516
DOC_CKS1_1 51 56 PF01111 0.426
DOC_CKS1_1 539 544 PF01111 0.518
DOC_CKS1_1 661 666 PF01111 0.518
DOC_CYCLIN_RxL_1 475 489 PF00134 0.518
DOC_CYCLIN_RxL_1 647 658 PF00134 0.473
DOC_CYCLIN_yCln2_LP_2 580 586 PF00134 0.438
DOC_CYCLIN_yCln2_LP_2 91 97 PF00134 0.335
DOC_CYCLIN_yCln2_LP_2 986 992 PF00134 0.386
DOC_MAPK_DCC_7 949 958 PF00069 0.288
DOC_MAPK_gen_1 477 485 PF00069 0.445
DOC_MAPK_gen_1 486 492 PF00069 0.388
DOC_MAPK_gen_1 494 501 PF00069 0.339
DOC_MAPK_gen_1 525 532 PF00069 0.488
DOC_MAPK_gen_1 615 623 PF00069 0.439
DOC_MAPK_gen_1 713 719 PF00069 0.413
DOC_MAPK_MEF2A_6 245 252 PF00069 0.413
DOC_MAPK_MEF2A_6 303 310 PF00069 0.266
DOC_MAPK_MEF2A_6 617 625 PF00069 0.408
DOC_MAPK_MEF2A_6 713 721 PF00069 0.470
DOC_MAPK_MEF2A_6 837 845 PF00069 0.323
DOC_MAPK_MEF2A_6 891 899 PF00069 0.213
DOC_MAPK_MEF2A_6 981 990 PF00069 0.374
DOC_MAPK_NFAT4_5 981 989 PF00069 0.374
DOC_PP1_RVXF_1 527 533 PF00149 0.463
DOC_PP1_RVXF_1 561 568 PF00149 0.413
DOC_PP1_RVXF_1 648 655 PF00149 0.481
DOC_PP2B_LxvP_1 4 7 PF13499 0.519
DOC_PP2B_LxvP_1 602 605 PF13499 0.438
DOC_PP2B_LxvP_1 986 989 PF13499 0.374
DOC_PP4_FxxP_1 782 785 PF00568 0.283
DOC_SPAK_OSR1_1 390 394 PF12202 0.439
DOC_USP7_MATH_1 326 330 PF00917 0.435
DOC_USP7_MATH_1 396 400 PF00917 0.466
DOC_USP7_MATH_1 588 592 PF00917 0.463
DOC_USP7_MATH_1 669 673 PF00917 0.493
DOC_USP7_MATH_1 720 724 PF00917 0.477
DOC_USP7_MATH_1 75 79 PF00917 0.300
DOC_USP7_MATH_1 930 934 PF00917 0.369
DOC_USP7_UBL2_3 729 733 PF12436 0.488
DOC_WW_Pin1_4 243 248 PF00397 0.413
DOC_WW_Pin1_4 280 285 PF00397 0.220
DOC_WW_Pin1_4 50 55 PF00397 0.415
DOC_WW_Pin1_4 535 540 PF00397 0.507
DOC_WW_Pin1_4 660 665 PF00397 0.474
DOC_WW_Pin1_4 706 711 PF00397 0.499
DOC_WW_Pin1_4 786 791 PF00397 0.225
DOC_WW_Pin1_4 951 956 PF00397 0.330
DOC_WW_Pin1_4 964 969 PF00397 0.257
LIG_14-3-3_CanoR_1 165 170 PF00244 0.504
LIG_14-3-3_CanoR_1 201 207 PF00244 0.438
LIG_14-3-3_CanoR_1 224 234 PF00244 0.425
LIG_14-3-3_CanoR_1 350 354 PF00244 0.457
LIG_14-3-3_CanoR_1 475 480 PF00244 0.523
LIG_14-3-3_CanoR_1 494 500 PF00244 0.296
LIG_14-3-3_CanoR_1 510 515 PF00244 0.282
LIG_14-3-3_CanoR_1 668 677 PF00244 0.493
LIG_14-3-3_CanoR_1 763 773 PF00244 0.266
LIG_Actin_WH2_2 288 305 PF00022 0.274
LIG_Actin_WH2_2 548 565 PF00022 0.413
LIG_BIR_II_1 1 5 PF00653 0.621
LIG_BRCT_BRCA1_1 51 55 PF00533 0.461
LIG_BRCT_BRCA1_1 947 951 PF00533 0.283
LIG_BRCT_BRCA1_2 51 57 PF00533 0.461
LIG_Clathr_ClatBox_1 166 170 PF01394 0.518
LIG_Clathr_ClatBox_1 898 902 PF01394 0.266
LIG_deltaCOP1_diTrp_1 831 836 PF00928 0.499
LIG_EH1_1 15 23 PF00400 0.463
LIG_EH1_1 94 102 PF00400 0.282
LIG_FHA_1 127 133 PF00498 0.427
LIG_FHA_1 136 142 PF00498 0.421
LIG_FHA_1 171 177 PF00498 0.461
LIG_FHA_1 209 215 PF00498 0.413
LIG_FHA_1 320 326 PF00498 0.266
LIG_FHA_1 357 363 PF00498 0.413
LIG_FHA_1 432 438 PF00498 0.414
LIG_FHA_1 504 510 PF00498 0.420
LIG_FHA_1 547 553 PF00498 0.470
LIG_FHA_1 616 622 PF00498 0.407
LIG_FHA_1 647 653 PF00498 0.408
LIG_FHA_1 798 804 PF00498 0.265
LIG_FHA_1 980 986 PF00498 0.384
LIG_FHA_2 225 231 PF00498 0.488
LIG_FHA_2 653 659 PF00498 0.419
LIG_FHA_2 861 867 PF00498 0.265
LIG_FHA_2 870 876 PF00498 0.244
LIG_GBD_Chelix_1 773 781 PF00786 0.266
LIG_Integrin_RGD_1 824 826 PF01839 0.263
LIG_LIR_Apic_2 292 297 PF02991 0.213
LIG_LIR_Apic_2 779 785 PF02991 0.384
LIG_LIR_Gen_1 388 398 PF02991 0.408
LIG_LIR_Gen_1 738 748 PF02991 0.451
LIG_LIR_Gen_1 831 841 PF02991 0.499
LIG_LIR_Gen_1 93 103 PF02991 0.289
LIG_LIR_Gen_1 967 977 PF02991 0.258
LIG_LIR_LC3C_4 896 900 PF02991 0.300
LIG_LIR_LC3C_4 915 918 PF02991 0.438
LIG_LIR_Nem_3 253 258 PF02991 0.413
LIG_LIR_Nem_3 288 294 PF02991 0.213
LIG_LIR_Nem_3 388 394 PF02991 0.422
LIG_LIR_Nem_3 52 58 PF02991 0.426
LIG_LIR_Nem_3 592 598 PF02991 0.476
LIG_LIR_Nem_3 653 657 PF02991 0.518
LIG_LIR_Nem_3 738 744 PF02991 0.448
LIG_LIR_Nem_3 758 764 PF02991 0.282
LIG_LIR_Nem_3 831 836 PF02991 0.479
LIG_LIR_Nem_3 93 98 PF02991 0.289
LIG_LIR_Nem_3 940 946 PF02991 0.315
LIG_LIR_Nem_3 967 972 PF02991 0.224
LIG_LIR_Nem_3 978 983 PF02991 0.185
LIG_LYPXL_SIV_4 31 39 PF13949 0.366
LIG_MAD2 140 148 PF02301 0.435
LIG_NRBOX 687 693 PF00104 0.413
LIG_NRBOX 992 998 PF00104 0.333
LIG_Pex14_1 290 294 PF04695 0.238
LIG_Pex14_2 853 857 PF04695 0.213
LIG_Pex14_2 947 951 PF04695 0.262
LIG_REV1ctd_RIR_1 833 841 PF16727 0.382
LIG_REV1ctd_RIR_1 944 953 PF16727 0.299
LIG_SH2_CRK 838 842 PF00017 0.269
LIG_SH2_NCK_1 32 36 PF00017 0.366
LIG_SH2_PTP2 265 268 PF00017 0.235
LIG_SH2_PTP2 294 297 PF00017 0.238
LIG_SH2_PTP2 844 847 PF00017 0.266
LIG_SH2_SRC 32 35 PF00017 0.366
LIG_SH2_SRC 764 767 PF00017 0.266
LIG_SH2_STAT5 265 268 PF00017 0.235
LIG_SH2_STAT5 294 297 PF00017 0.263
LIG_SH2_STAT5 764 767 PF00017 0.266
LIG_SH2_STAT5 844 847 PF00017 0.266
LIG_SH2_STAT5 943 946 PF00017 0.252
LIG_SH3_2 645 650 PF14604 0.393
LIG_SH3_3 4 10 PF00018 0.477
LIG_SH3_3 45 51 PF00018 0.422
LIG_SH3_3 536 542 PF00018 0.466
LIG_SH3_3 642 648 PF00018 0.491
LIG_SH3_3 915 921 PF00018 0.474
LIG_SH3_3 968 974 PF00018 0.274
LIG_SUMO_SIM_anti_2 896 902 PF11976 0.255
LIG_SUMO_SIM_anti_2 915 920 PF11976 0.371
LIG_SUMO_SIM_anti_2 959 965 PF11976 0.166
LIG_SUMO_SIM_anti_2 982 987 PF11976 0.384
LIG_SUMO_SIM_par_1 165 173 PF11976 0.434
LIG_SUMO_SIM_par_1 622 627 PF11976 0.425
LIG_SUMO_SIM_par_1 85 93 PF11976 0.394
LIG_SUMO_SIM_par_1 896 902 PF11976 0.261
LIG_SUMO_SIM_par_1 96 102 PF11976 0.377
LIG_SUMO_SIM_par_1 981 987 PF11976 0.361
LIG_TRAF2_1 285 288 PF00917 0.318
LIG_TRAF2_1 519 522 PF00917 0.425
LIG_TYR_ITIM 263 268 PF00017 0.235
LIG_TYR_ITIM 30 35 PF00017 0.366
LIG_UBA3_1 17 25 PF00899 0.497
LIG_UBA3_1 450 456 PF00899 0.413
LIG_WRC_WIRS_1 76 81 PF05994 0.300
LIG_WRC_WIRS_1 867 872 PF05994 0.299
LIG_WW_3 603 607 PF00397 0.413
MOD_CDK_SPK_2 538 543 PF00069 0.518
MOD_CDK_SPxxK_3 50 57 PF00069 0.425
MOD_CDK_SPxxK_3 660 667 PF00069 0.474
MOD_CDK_SPxxK_3 706 713 PF00069 0.499
MOD_CK1_1 1001 1007 PF00069 0.605
MOD_CK1_1 344 350 PF00069 0.450
MOD_CK1_1 356 362 PF00069 0.413
MOD_CK1_1 426 432 PF00069 0.510
MOD_CK1_1 495 501 PF00069 0.464
MOD_CK1_1 538 544 PF00069 0.520
MOD_CK1_1 591 597 PF00069 0.410
MOD_CK1_1 869 875 PF00069 0.259
MOD_CK2_1 224 230 PF00069 0.488
MOD_CK2_1 286 292 PF00069 0.235
MOD_CK2_1 365 371 PF00069 0.451
MOD_CK2_1 553 559 PF00069 0.454
MOD_CK2_1 58 64 PF00069 0.508
MOD_CK2_1 652 658 PF00069 0.431
MOD_CK2_1 720 726 PF00069 0.492
MOD_CK2_1 964 970 PF00069 0.166
MOD_GlcNHglycan 1011 1014 PF01048 0.479
MOD_GlcNHglycan 1020 1023 PF01048 0.500
MOD_GlcNHglycan 376 380 PF01048 0.318
MOD_GlcNHglycan 459 462 PF01048 0.305
MOD_GlcNHglycan 555 558 PF01048 0.225
MOD_GlcNHglycan 672 675 PF01048 0.261
MOD_GlcNHglycan 722 725 PF01048 0.292
MOD_GSK3_1 165 172 PF00069 0.518
MOD_GSK3_1 222 229 PF00069 0.454
MOD_GSK3_1 349 356 PF00069 0.445
MOD_GSK3_1 361 368 PF00069 0.413
MOD_GSK3_1 371 378 PF00069 0.413
MOD_GSK3_1 382 389 PF00069 0.413
MOD_GSK3_1 396 403 PF00069 0.384
MOD_GSK3_1 46 53 PF00069 0.423
MOD_GSK3_1 486 493 PF00069 0.418
MOD_GSK3_1 497 504 PF00069 0.423
MOD_GSK3_1 646 653 PF00069 0.399
MOD_GSK3_1 856 863 PF00069 0.243
MOD_GSK3_1 908 915 PF00069 0.237
MOD_GSK3_1 975 982 PF00069 0.298
MOD_N-GLC_1 400 405 PF02516 0.235
MOD_N-GLC_1 578 583 PF02516 0.217
MOD_N-GLC_1 706 711 PF02516 0.299
MOD_N-GLC_1 755 760 PF02516 0.251
MOD_N-GLC_1 912 917 PF02516 0.213
MOD_NEK2_1 169 174 PF00069 0.413
MOD_NEK2_1 17 22 PF00069 0.489
MOD_NEK2_1 258 263 PF00069 0.345
MOD_NEK2_1 417 422 PF00069 0.474
MOD_NEK2_1 457 462 PF00069 0.518
MOD_NEK2_1 490 495 PF00069 0.425
MOD_NEK2_1 544 549 PF00069 0.498
MOD_NEK2_1 58 63 PF00069 0.431
MOD_NEK2_1 652 657 PF00069 0.446
MOD_NEK2_1 755 760 PF00069 0.456
MOD_NEK2_1 765 770 PF00069 0.222
MOD_NEK2_1 876 881 PF00069 0.316
MOD_NEK2_1 937 942 PF00069 0.331
MOD_NEK2_1 984 989 PF00069 0.323
MOD_NEK2_1 99 104 PF00069 0.339
MOD_PIKK_1 135 141 PF00454 0.518
MOD_PIKK_1 58 64 PF00454 0.366
MOD_PK_1 497 503 PF00069 0.425
MOD_PKA_1 486 492 PF00069 0.475
MOD_PKA_1 525 531 PF00069 0.454
MOD_PKA_1 630 636 PF00069 0.425
MOD_PKA_2 1001 1007 PF00069 0.586
MOD_PKA_2 208 214 PF00069 0.499
MOD_PKA_2 349 355 PF00069 0.446
MOD_PKA_2 495 501 PF00069 0.413
MOD_PKA_2 525 531 PF00069 0.439
MOD_PKA_2 553 559 PF00069 0.482
MOD_PKA_2 919 925 PF00069 0.413
MOD_Plk_1 169 175 PF00069 0.439
MOD_Plk_1 176 182 PF00069 0.410
MOD_Plk_1 286 292 PF00069 0.284
MOD_Plk_1 426 432 PF00069 0.413
MOD_Plk_1 591 597 PF00069 0.425
MOD_Plk_1 63 69 PF00069 0.282
MOD_Plk_1 912 918 PF00069 0.413
MOD_Plk_2-3 341 347 PF00069 0.478
MOD_Plk_2-3 371 377 PF00069 0.518
MOD_Plk_2-3 9 15 PF00069 0.532
MOD_Plk_4 17 23 PF00069 0.504
MOD_Plk_4 176 182 PF00069 0.438
MOD_Plk_4 202 208 PF00069 0.434
MOD_Plk_4 258 264 PF00069 0.337
MOD_Plk_4 286 292 PF00069 0.299
MOD_Plk_4 349 355 PF00069 0.446
MOD_Plk_4 426 432 PF00069 0.520
MOD_Plk_4 510 516 PF00069 0.438
MOD_Plk_4 591 597 PF00069 0.425
MOD_Plk_4 63 69 PF00069 0.282
MOD_Plk_4 740 746 PF00069 0.449
MOD_Plk_4 893 899 PF00069 0.256
MOD_Plk_4 912 918 PF00069 0.367
MOD_Plk_4 937 943 PF00069 0.309
MOD_Plk_4 979 985 PF00069 0.285
MOD_ProDKin_1 243 249 PF00069 0.413
MOD_ProDKin_1 280 286 PF00069 0.220
MOD_ProDKin_1 50 56 PF00069 0.415
MOD_ProDKin_1 535 541 PF00069 0.507
MOD_ProDKin_1 660 666 PF00069 0.474
MOD_ProDKin_1 706 712 PF00069 0.499
MOD_ProDKin_1 786 792 PF00069 0.225
MOD_ProDKin_1 951 957 PF00069 0.330
MOD_ProDKin_1 964 970 PF00069 0.257
MOD_SUMO_for_1 584 587 PF00179 0.499
MOD_SUMO_rev_2 237 247 PF00179 0.415
MOD_SUMO_rev_2 976 983 PF00179 0.195
TRG_DiLeu_BaEn_1 254 259 PF01217 0.413
TRG_DiLeu_BaEn_1 447 452 PF01217 0.438
TRG_DiLeu_BaEn_1 912 917 PF01217 0.425
TRG_DiLeu_BaLyEn_6 162 167 PF01217 0.518
TRG_DiLeu_BaLyEn_6 693 698 PF01217 0.392
TRG_ENDOCYTIC_2 265 268 PF00928 0.235
TRG_ENDOCYTIC_2 32 35 PF00928 0.366
TRG_ENDOCYTIC_2 838 841 PF00928 0.269
TRG_ENDOCYTIC_2 844 847 PF00928 0.271
TRG_ENDOCYTIC_2 943 946 PF00928 0.266
TRG_ER_diArg_1 639 641 PF00400 0.518
TRG_ER_diArg_1 822 824 PF00400 0.455
TRG_ER_FFAT_2 865 875 PF00635 0.290
TRG_Pf-PMV_PEXEL_1 140 144 PF00026 0.235
TRG_Pf-PMV_PEXEL_1 165 170 PF00026 0.318
TRG_Pf-PMV_PEXEL_1 28 33 PF00026 0.288
TRG_Pf-PMV_PEXEL_1 37 41 PF00026 0.295
TRG_Pf-PMV_PEXEL_1 477 482 PF00026 0.229
TRG_Pf-PMV_PEXEL_1 570 574 PF00026 0.299

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3Y1 Leptomonas seymouri 77% 100%
A0A0N1HWG6 Leptomonas seymouri 30% 92%
A0A0N1HZI4 Leptomonas seymouri 22% 82%
A0A0N1I8I8 Leptomonas seymouri 27% 84%
A0A0N1PFH3 Leptomonas seymouri 30% 84%
A0A0S4J1M1 Bodo saltans 28% 93%
A0A0S4J5A1 Bodo saltans 31% 96%
A0A0S4J6U4 Bodo saltans 29% 94%
A0A0S4JA92 Bodo saltans 28% 100%
A0A0S4JRV4 Bodo saltans 30% 100%
A0A0S4KIG5 Bodo saltans 63% 100%
A0A0S4KNQ6 Bodo saltans 28% 92%
A0A1X0NNY6 Trypanosomatidae 69% 100%
A0A1X0NPD9 Trypanosomatidae 27% 93%
A0A1X0NTI6 Trypanosomatidae 28% 90%
A0A1X0P0Y8 Trypanosomatidae 25% 93%
A0A1X0P689 Trypanosomatidae 31% 98%
A0A3R7KM63 Trypanosoma rangeli 28% 98%
A0A3R7MRX8 Trypanosoma rangeli 30% 98%
A0A3S5H5Y9 Leishmania donovani 29% 93%
A0A3S5ISK9 Trypanosoma rangeli 27% 96%
A0A3S7WPW0 Leishmania donovani 29% 91%
A0A3S7WUG2 Leishmania donovani 29% 90%
A0A3S7X978 Leishmania donovani 31% 92%
A0A422NTS7 Trypanosoma rangeli 67% 100%
A0A451EJU6 Leishmania donovani 100% 100%
A2VDL6 Bos taurus 31% 100%
A4H3S2 Leishmania braziliensis 86% 100%
A4H514 Leishmania braziliensis 28% 100%
A4H553 Leishmania braziliensis 21% 82%
A4H7E2 Leishmania braziliensis 21% 100%
A4H903 Leishmania braziliensis 29% 100%
A4HMM8 Leishmania braziliensis 31% 100%
A4HT82 Leishmania infantum 31% 100%
A4HTF0 Leishmania infantum 29% 100%
A4HXD4 Leishmania infantum 29% 90%
A4IBA6 Leishmania infantum 31% 92%
A7L9Z8 Mus musculus 32% 100%
C9ZPL1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 68% 100%
C9ZUN6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 95%
C9ZZN4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 98%
D0A4V8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 93%
D0ZTB2 Salmonella typhimurium (strain 14028s / SGSC 2262) 27% 100%
D2WKD8 Sus scrofa 31% 100%
D3K0R6 Bos taurus 28% 85%
E9AF31 Leishmania major 31% 100%
E9AJY3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 100%
E9AL76 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 100%
E9AL78 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 100%
E9AR29 Leishmania mexicana (strain MHOM/GT/2001/U1103) 30% 100%
E9B686 Leishmania mexicana (strain MHOM/GT/2001/U1103) 31% 100%
G5E829 Mus musculus 30% 84%
G5EBH1 Caenorhabditis elegans 23% 95%
J9VQQ3 Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) 28% 72%
O14022 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 23% 93%
O14983 Homo sapiens 49% 100%
O22218 Arabidopsis thaliana 29% 99%
O23087 Arabidopsis thaliana 43% 97%
O34431 Bacillus subtilis (strain 168) 35% 100%
O43108 Yarrowia lipolytica (strain CLIB 122 / E 150) 35% 100%
O46674 Canis lupus familiaris 48% 100%
O55143 Mus musculus 48% 98%
O59868 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 33% 100%
O64806 Arabidopsis thaliana 28% 100%
O75185 Homo sapiens 32% 100%
O77696 Sus scrofa 48% 100%
O81108 Arabidopsis thaliana 29% 100%
P04074 Ovis aries 32% 100%
P04191 Oryctolagus cuniculus 49% 100%
P05023 Homo sapiens 32% 100%
P05024 Sus scrofa 32% 100%
P05025 Tetronarce californica 31% 100%
P06685 Rattus norvegicus 32% 100%
P06686 Rattus norvegicus 31% 100%
P06687 Rattus norvegicus 30% 100%
P09572 Gallus gallus 33% 100%
P09626 Rattus norvegicus 32% 99%
P0ABB8 Escherichia coli (strain K12) 26% 100%
P0ABB9 Escherichia coli O157:H7 26% 100%
P11505 Rattus norvegicus 30% 84%
P11506 Rattus norvegicus 30% 82%
P11507 Rattus norvegicus 48% 98%
P11607 Sus scrofa 48% 98%
P13585 Gallus gallus 49% 100%
P13586 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 33% 100%
P13587 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 28% 94%
P13607 Drosophila melanogaster 32% 98%
P13637 Homo sapiens 30% 100%
P16615 Homo sapiens 48% 98%
P17326 Artemia franciscana 31% 100%
P18596 Rattus norvegicus 49% 100%
P18907 Equus caballus 32% 100%
P19156 Sus scrofa 31% 99%
P19456 Arabidopsis thaliana 27% 100%
P20020 Homo sapiens 28% 84%
P20431 Arabidopsis thaliana 28% 100%
P20647 Oryctolagus cuniculus 48% 98%
P20648 Homo sapiens 31% 99%
P22180 Solanum lycopersicum 26% 100%
P22189 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 29% 99%
P22700 Drosophila melanogaster 48% 100%
P23220 Sus scrofa 30% 84%
P23634 Homo sapiens 27% 82%
P24797 Gallus gallus 32% 100%
P24798 Gallus gallus 31% 100%
P25489 Catostomus commersonii 32% 100%
P27112 Oryctolagus cuniculus 31% 99%
P28774 Artemia franciscana 30% 100%
P30714 Rhinella marina 30% 100%
P35315 Trypanosoma brucei brucei 68% 100%
P35316 Artemia franciscana 48% 100%
P35317 Hydra vulgaris 30% 99%
P36640 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 27% 100%
P37278 Synechococcus elongatus (strain PCC 7942 / FACHB-805) 34% 100%
P37367 Synechocystis sp. (strain PCC 6803 / Kazusa) 34% 100%
P47317 Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) 31% 100%
P50993 Homo sapiens 31% 100%
P50996 Canis lupus familiaris 31% 99%
P50997 Canis lupus familiaris 31% 100%
P54209 Dunaliella bioculata 46% 99%
P54678 Dictyostelium discoideum 30% 92%
P54707 Homo sapiens 32% 98%
P54708 Rattus norvegicus 33% 99%
P57709 Bos taurus 33% 100%
P58165 Oreochromis mossambicus 30% 92%
P58312 Oreochromis mossambicus 31% 100%
P63688 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 34% 100%
P70083 Makaira nigricans 49% 100%
P78036 Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) 30% 100%
P83970 Triticum aestivum 26% 100%
P90747 Caenorhabditis elegans 23% 87%
P92939 Arabidopsis thaliana 44% 96%
P98194 Homo sapiens 33% 100%
P9WPS8 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 34% 100%
P9WPS9 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 34% 100%
Q00779 Felis catus 48% 100%
Q00804 Oryctolagus cuniculus 31% 84%
Q01814 Homo sapiens 29% 82%
Q01896 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 28% 94%
Q03194 Nicotiana plumbaginifolia 27% 100%
Q03669 Gallus gallus 48% 98%
Q08435 Nicotiana plumbaginifolia 26% 100%
Q08436 Nicotiana plumbaginifolia 27% 100%
Q08DA1 Bos taurus 32% 100%
Q0VCY0 Bos taurus 49% 100%
Q12691 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 28% 94%
Q13733 Homo sapiens 31% 99%
Q16720 Homo sapiens 28% 84%
Q21286 Caenorhabditis elegans 23% 85%
Q292Q0 Drosophila pseudoobscura pseudoobscura 48% 100%
Q2QMX9 Oryza sativa subsp. japonica 28% 100%
Q2QY12 Oryza sativa subsp. japonica 28% 98%
Q2RAS0 Oryza sativa subsp. japonica 28% 100%
Q37145 Arabidopsis thaliana 30% 100%
Q3TYU2 Mus musculus 22% 84%
Q42556 Arabidopsis thaliana 27% 100%
Q42883 Solanum lycopersicum 44% 98%
Q43128 Arabidopsis thaliana 26% 100%
Q4QED4 Leishmania major 30% 100%
Q4QG01 Leishmania major 22% 100%
Q4QII2 Leishmania major 21% 82%
Q4QIM6 Leishmania major 27% 100%
Q4QIM8 Leishmania major 29% 100%
Q4VNC0 Homo sapiens 22% 84%
Q4VNC1 Homo sapiens 23% 86%
Q5R5K5 Pongo abelii 34% 100%
Q5RCD8 Pongo abelii 31% 100%
Q5RDR3 Pongo abelii 32% 100%
Q5XF89 Mus musculus 21% 84%
Q5ZKB7 Gallus gallus 22% 85%
Q64392 Cavia porcellus 32% 99%
Q64436 Mus musculus 30% 99%
Q64518 Mus musculus 49% 100%
Q64541 Rattus norvegicus 30% 100%
Q64542 Rattus norvegicus 27% 85%
Q64566 Rattus norvegicus 33% 100%
Q64568 Rattus norvegicus 28% 81%
Q64578 Rattus norvegicus 50% 100%
Q65X71 Oryza sativa subsp. japonica 30% 100%
Q6ATV4 Oryza sativa subsp. japonica 30% 99%
Q6DFW5 Mus musculus 21% 87%
Q6PIC6 Mus musculus 30% 100%
Q6PIE5 Mus musculus 31% 100%
Q6Q477 Mus musculus 28% 85%
Q6RWA9 Taenia solium 30% 100%
Q73E41 Bacillus cereus (strain ATCC 10987 / NRS 248) 34% 100%
Q7PPA5 Anopheles gambiae 49% 100%
Q7X8B5 Oryza sativa subsp. japonica 29% 94%
Q7XEK4 Oryza sativa subsp. japonica 31% 99%
Q7XPY2 Oryza sativa subsp. japonica 28% 100%
Q80XR2 Mus musculus 33% 100%
Q8R429 Mus musculus 50% 100%
Q8R4C1 Rattus norvegicus 32% 100%
Q8RUN1 Oryza sativa subsp. japonica 30% 98%
Q8VDN2 Mus musculus 32% 100%
Q8Y8Q5 Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) 33% 100%
Q92030 Anguilla anguilla 32% 100%
Q92036 Rhinella marina 30% 98%
Q92105 Pelophylax lessonae 49% 100%
Q92123 Xenopus laevis 32% 100%
Q92126 Xenopus laevis 32% 99%
Q93084 Homo sapiens 48% 100%
Q95JN5 Macaca fascicularis 21% 83%
Q95Z93 Leishmania major 95% 100%
Q98SH2 Gallus gallus 29% 85%
Q9CFU9 Lactococcus lactis subsp. lactis (strain IL1403) 35% 100%
Q9H7F0 Homo sapiens 21% 83%
Q9HDW7 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 29% 79%
Q9LF79 Arabidopsis thaliana 29% 95%
Q9LIK7 Arabidopsis thaliana 30% 100%
Q9LU41 Arabidopsis thaliana 28% 94%
Q9LV11 Arabidopsis thaliana 27% 100%
Q9LY32 Arabidopsis thaliana 26% 100%
Q9LY77 Arabidopsis thaliana 30% 99%
Q9M2A0 Arabidopsis thaliana 27% 100%
Q9M2L4 Arabidopsis thaliana 28% 100%
Q9N0Z4 Oryctolagus cuniculus 22% 88%
Q9N0Z6 Oryctolagus cuniculus 32% 100%
Q9NQ11 Homo sapiens 22% 87%
Q9R0K7 Mus musculus 28% 85%
Q9SH76 Arabidopsis thaliana 26% 100%
Q9SJB3 Arabidopsis thaliana 25% 100%
Q9SU58 Arabidopsis thaliana 27% 100%
Q9SY55 Arabidopsis thaliana 46% 100%
Q9SZR1 Arabidopsis thaliana 30% 96%
Q9TV52 Oryctolagus cuniculus 30% 94%
Q9WV27 Mus musculus 30% 99%
Q9XES1 Arabidopsis thaliana 44% 96%
Q9Y2G3 Homo sapiens 22% 87%
Q9YGL9 Gallus gallus 47% 100%
Q9YH26 Oreochromis mossambicus 32% 100%
Q9Z1W8 Mus musculus 33% 99%
V5B873 Trypanosoma cruzi 28% 93%
V5BHI7 Trypanosoma cruzi 22% 100%
V5BHZ2 Trypanosoma cruzi 31% 98%
V5BLM1 Trypanosoma cruzi 67% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS