MORN repeat family protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

MORN repeat - putative

Species:

Leishmania infantum

UniProt:

A4HRY3_LEIIN

TriTrypDb:

LINF_030014800

Length:

325

Annotations

Annotations by Jardim et al.

Flagella, MORN repeat

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Cellular components
Term	Name	Level	Count
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HRY3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HRY3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	15	19	PF00656	0.386
CLV_PCSK_FUR_1	184	188	PF00082	0.276
CLV_PCSK_KEX2_1	186	188	PF00082	0.276
CLV_PCSK_KEX2_1	209	211	PF00082	0.257
CLV_PCSK_KEX2_1	300	302	PF00082	0.418
CLV_PCSK_PC1ET2_1	186	188	PF00082	0.276
CLV_PCSK_PC1ET2_1	209	211	PF00082	0.257
CLV_PCSK_PC1ET2_1	300	302	PF00082	0.391
CLV_PCSK_SKI1_1	146	150	PF00082	0.500
DOC_ANK_TNKS_1	162	169	PF00023	0.431
DOC_MAPK_gen_1	113	123	PF00069	0.397
DOC_MAPK_gen_1	24	30	PF00069	0.428
DOC_USP7_MATH_1	242	246	PF00917	0.310
DOC_USP7_UBL2_3	229	233	PF12436	0.298
DOC_USP7_UBL2_3	272	276	PF12436	0.406
LIG_deltaCOP1_diTrp_1	250	256	PF00928	0.413
LIG_deltaCOP1_diTrp_1	50	56	PF00928	0.336
LIG_EH1_1	163	171	PF00400	0.443
LIG_FHA_1	305	311	PF00498	0.470
LIG_FHA_1	75	81	PF00498	0.345
LIG_FHA_2	45	51	PF00498	0.450
LIG_LIR_Nem_3	234	239	PF02991	0.302
LIG_LIR_Nem_3	285	291	PF02991	0.415
LIG_LYPXL_yS_3	288	291	PF13949	0.436
LIG_Pex14_1	52	56	PF04695	0.340
LIG_Pex14_2	67	71	PF04695	0.464
LIG_REV1ctd_RIR_1	107	118	PF16727	0.274
LIG_SH2_CRK	81	85	PF00017	0.346
LIG_SH2_GRB2like	218	221	PF00017	0.257
LIG_SH2_NCK_1	34	38	PF00017	0.451
LIG_SH2_PTP2	120	123	PF00017	0.263
LIG_SH2_SRC	218	221	PF00017	0.257
LIG_SH2_STAP1	34	38	PF00017	0.393
LIG_SH2_STAT5	120	123	PF00017	0.287
LIG_SH2_STAT5	182	185	PF00017	0.333
LIG_SH2_STAT5	218	221	PF00017	0.265
LIG_SH2_STAT5	29	32	PF00017	0.356
LIG_SH3_3	300	306	PF00018	0.399
LIG_SUMO_SIM_anti_2	137	142	PF11976	0.454
LIG_TYR_ITIM	286	291	PF00017	0.336
MOD_CK1_1	101	107	PF00069	0.420
MOD_CK1_1	60	66	PF00069	0.413
MOD_CK1_1	74	80	PF00069	0.275
MOD_CK2_1	264	270	PF00069	0.352
MOD_CK2_1	44	50	PF00069	0.541
MOD_Cter_Amidation	111	114	PF01082	0.273
MOD_Cter_Amidation	184	187	PF01082	0.276
MOD_GlcNHglycan	100	103	PF01048	0.294
MOD_GlcNHglycan	224	227	PF01048	0.257
MOD_GlcNHglycan	307	310	PF01048	0.383
MOD_GlcNHglycan	61	65	PF01048	0.492
MOD_GlcNHglycan	91	94	PF01048	0.271
MOD_GSK3_1	121	128	PF00069	0.253
MOD_NEK2_1	293	298	PF00069	0.361
MOD_NEK2_1	71	76	PF00069	0.284
MOD_Plk_2-3	44	50	PF00069	0.481
MOD_Plk_4	196	202	PF00069	0.257
MOD_Plk_4	264	270	PF00069	0.401
MOD_SUMO_rev_2	267	273	PF00179	0.393
MOD_SUMO_rev_2	3	9	PF00179	0.617
TRG_ENDOCYTIC_2	120	123	PF00928	0.291
TRG_ENDOCYTIC_2	216	219	PF00928	0.248
TRG_ENDOCYTIC_2	288	291	PF00928	0.435
TRG_Pf-PMV_PEXEL_1	278	282	PF00026	0.515

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HVW7	Leptomonas seymouri	82%	100%
A0A0S4IT41	Bodo saltans	54%	100%
A0A0S4KIY0	Bodo saltans	34%	91%
A0A1X0P8X9	Trypanosomatidae	60%	100%
A0A451EJU5	Leishmania donovani	99%	100%
A4H3Q9	Leishmania braziliensis	86%	100%
A4HPP6	Leishmania braziliensis	23%	100%
C9ZKJ2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	63%	100%
E9ACP2	Leishmania major	98%	100%
E9AJY1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
V5DTY1	Trypanosoma cruzi	63%	100%