Putative long chain fatty Acyl CoA synthetase

Quick info Annotations Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

long-chain-fatty-acid-CoA ligase - putative

Species:

Leishmania infantum

UniProt:

A4HRT4_LEIIN

TriTrypDb:

LINF_030007100

Length:

704

Annotations

Annotations by Jardim et al.

Fatty acid metabolism, long chain fatty Acyl CoA synthetase

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 8
Forrest at al. (procyclic)	yes	yes: 8
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 33

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 12

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 49
NetGPI	no	yes: 0, no: 49

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	5
GO:0005737	cytoplasm	2	5
GO:0005783	endoplasmic reticulum	5	5
GO:0016020	membrane	2	5
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	5
GO:0043226	organelle	2	5
GO:0043227	membrane-bounded organelle	3	5
GO:0043229	intracellular organelle	3	5
GO:0043231	intracellular membrane-bounded organelle	4	5
GO:0097014	ciliary plasm	5	5
GO:0099568	cytoplasmic region	3	5
GO:0110165	cellular anatomical entity	1	5

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4HRT4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HRT4

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	35
GO:0004467	long-chain fatty acid-CoA ligase activity	3	33
GO:0015645	fatty acid ligase activity	2	33
GO:0016405	CoA-ligase activity	4	33
GO:0016874	ligase activity	2	35
GO:0016877	ligase activity, forming carbon-sulfur bonds	3	33
GO:0016878	acid-thiol ligase activity	4	33
GO:0140657	ATP-dependent activity	1	33

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	102	106	PF00656	0.627
CLV_C14_Caspase3-7	649	653	PF00656	0.544
CLV_NRD_NRD_1	106	108	PF00675	0.533
CLV_NRD_NRD_1	379	381	PF00675	0.283
CLV_NRD_NRD_1	393	395	PF00675	0.283
CLV_NRD_NRD_1	425	427	PF00675	0.468
CLV_NRD_NRD_1	686	688	PF00675	0.415
CLV_NRD_NRD_1	90	92	PF00675	0.449
CLV_PCSK_FUR_1	82	86	PF00082	0.302
CLV_PCSK_KEX2_1	379	381	PF00082	0.362
CLV_PCSK_KEX2_1	393	395	PF00082	0.314
CLV_PCSK_KEX2_1	419	421	PF00082	0.274
CLV_PCSK_KEX2_1	59	61	PF00082	0.462
CLV_PCSK_KEX2_1	685	687	PF00082	0.440
CLV_PCSK_KEX2_1	84	86	PF00082	0.452
CLV_PCSK_PC1ET2_1	393	395	PF00082	0.342
CLV_PCSK_PC1ET2_1	419	421	PF00082	0.227
CLV_PCSK_PC1ET2_1	59	61	PF00082	0.324
CLV_PCSK_PC1ET2_1	685	687	PF00082	0.423
CLV_PCSK_PC1ET2_1	84	86	PF00082	0.461
CLV_PCSK_SKI1_1	108	112	PF00082	0.501
CLV_PCSK_SKI1_1	206	210	PF00082	0.374
CLV_PCSK_SKI1_1	394	398	PF00082	0.343
CLV_PCSK_SKI1_1	406	410	PF00082	0.337
CLV_PCSK_SKI1_1	419	423	PF00082	0.357
CLV_PCSK_SKI1_1	532	536	PF00082	0.393
CLV_PCSK_SKI1_1	613	617	PF00082	0.463
CLV_PCSK_SKI1_1	640	644	PF00082	0.410
CLV_PCSK_SKI1_1	91	95	PF00082	0.473
DOC_CYCLIN_yCln2_LP_2	515	521	PF00134	0.325
DOC_MAPK_MEF2A_6	266	273	PF00069	0.351
DOC_MAPK_MEF2A_6	364	371	PF00069	0.344
DOC_MAPK_NFAT4_5	266	274	PF00069	0.466
DOC_PP2B_LxvP_1	386	389	PF13499	0.320
DOC_PP4_FxxP_1	353	356	PF00568	0.357
DOC_USP7_MATH_1	329	333	PF00917	0.373
DOC_USP7_MATH_1	599	603	PF00917	0.345
DOC_USP7_MATH_1	642	646	PF00917	0.352
DOC_USP7_MATH_1	67	71	PF00917	0.549
DOC_USP7_UBL2_3	395	399	PF12436	0.393
DOC_USP7_UBL2_3	522	526	PF12436	0.345
DOC_USP7_UBL2_3	562	566	PF12436	0.337
DOC_USP7_UBL2_3	621	625	PF12436	0.527
DOC_USP7_UBL2_3	80	84	PF12436	0.471
DOC_USP7_UBL2_3	94	98	PF12436	0.548
DOC_WW_Pin1_4	342	347	PF00397	0.349
DOC_WW_Pin1_4	411	416	PF00397	0.350
DOC_WW_Pin1_4	669	674	PF00397	0.441
LIG_14-3-3_CanoR_1	249	259	PF00244	0.393
LIG_14-3-3_CanoR_1	49	58	PF00244	0.493
LIG_14-3-3_CanoR_1	655	659	PF00244	0.451
LIG_14-3-3_CanoR_1	82	90	PF00244	0.441
LIG_Actin_WH2_2	626	642	PF00022	0.306
LIG_APCC_ABBA_1	150	155	PF00400	0.340
LIG_BRCT_BRCA1_1	697	701	PF00533	0.267
LIG_deltaCOP1_diTrp_1	154	160	PF00928	0.324
LIG_FHA_1	147	153	PF00498	0.405
LIG_FHA_1	219	225	PF00498	0.323
LIG_FHA_1	329	335	PF00498	0.399
LIG_FHA_1	463	469	PF00498	0.353
LIG_FHA_1	474	480	PF00498	0.333
LIG_FHA_1	488	494	PF00498	0.241
LIG_FHA_1	541	547	PF00498	0.327
LIG_FHA_1	552	558	PF00498	0.337
LIG_FHA_1	582	588	PF00498	0.442
LIG_FHA_2	100	106	PF00498	0.542
LIG_FHA_2	232	238	PF00498	0.446
LIG_FHA_2	346	352	PF00498	0.365
LIG_FHA_2	51	57	PF00498	0.441
LIG_FHA_2	647	653	PF00498	0.484
LIG_LIR_Apic_2	351	356	PF02991	0.364
LIG_LIR_Gen_1	122	133	PF02991	0.359
LIG_LIR_Gen_1	155	165	PF02991	0.339
LIG_LIR_Gen_1	175	186	PF02991	0.342
LIG_LIR_Gen_1	447	458	PF02991	0.339
LIG_LIR_Gen_1	480	488	PF02991	0.421
LIG_LIR_Gen_1	571	578	PF02991	0.419
LIG_LIR_Gen_1	602	609	PF02991	0.501
LIG_LIR_Gen_1	635	646	PF02991	0.474
LIG_LIR_Gen_1	657	666	PF02991	0.480
LIG_LIR_Gen_1	691	701	PF02991	0.364
LIG_LIR_Nem_3	122	128	PF02991	0.347
LIG_LIR_Nem_3	155	161	PF02991	0.340
LIG_LIR_Nem_3	17	23	PF02991	0.414
LIG_LIR_Nem_3	175	181	PF02991	0.336
LIG_LIR_Nem_3	210	215	PF02991	0.223
LIG_LIR_Nem_3	235	241	PF02991	0.322
LIG_LIR_Nem_3	25	29	PF02991	0.426
LIG_LIR_Nem_3	314	319	PF02991	0.311
LIG_LIR_Nem_3	361	366	PF02991	0.323
LIG_LIR_Nem_3	447	453	PF02991	0.339
LIG_LIR_Nem_3	480	484	PF02991	0.340
LIG_LIR_Nem_3	571	575	PF02991	0.457
LIG_LIR_Nem_3	602	606	PF02991	0.509
LIG_LIR_Nem_3	627	632	PF02991	0.431
LIG_LIR_Nem_3	657	661	PF02991	0.495
LIG_LIR_Nem_3	691	696	PF02991	0.389
LIG_Pex14_1	315	319	PF04695	0.466
LIG_PTB_Apo_2	449	456	PF02174	0.353
LIG_PTB_Apo_2	60	67	PF02174	0.317
LIG_PTB_Apo_2	623	630	PF02174	0.489
LIG_PTB_Apo_2	687	694	PF02174	0.552
LIG_PTB_Phospho_1	60	66	PF10480	0.319
LIG_PTB_Phospho_1	687	693	PF10480	0.291
LIG_REV1ctd_RIR_1	414	424	PF16727	0.230
LIG_SH2_CRK	178	182	PF00017	0.347
LIG_SH2_CRK	343	347	PF00017	0.345
LIG_SH2_CRK	434	438	PF00017	0.320
LIG_SH2_CRK	481	485	PF00017	0.389
LIG_SH2_CRK	90	94	PF00017	0.424
LIG_SH2_GRB2like	178	181	PF00017	0.356
LIG_SH2_NCK_1	481	485	PF00017	0.421
LIG_SH2_PTP2	603	606	PF00017	0.494
LIG_SH2_SRC	693	696	PF00017	0.402
LIG_SH2_STAP1	125	129	PF00017	0.381
LIG_SH2_STAP1	238	242	PF00017	0.446
LIG_SH2_STAP1	693	697	PF00017	0.404
LIG_SH2_STAT3	29	32	PF00017	0.447
LIG_SH2_STAT3	524	527	PF00017	0.325
LIG_SH2_STAT5	114	117	PF00017	0.348
LIG_SH2_STAT5	225	228	PF00017	0.365
LIG_SH2_STAT5	274	277	PF00017	0.350
LIG_SH2_STAT5	293	296	PF00017	0.448
LIG_SH2_STAT5	316	319	PF00017	0.346
LIG_SH2_STAT5	572	575	PF00017	0.417
LIG_SH2_STAT5	603	606	PF00017	0.345
LIG_SH3_3	112	118	PF00018	0.364
LIG_SH3_3	366	372	PF00018	0.281
LIG_SUMO_SIM_anti_2	267	273	PF11976	0.421
LIG_SUMO_SIM_anti_2	602	608	PF11976	0.502
LIG_SUMO_SIM_anti_2	70	76	PF11976	0.503
LIG_SUMO_SIM_par_1	148	156	PF11976	0.316
LIG_SUMO_SIM_par_1	605	610	PF11976	0.486
LIG_TRAF2_1	234	237	PF00917	0.448
LIG_TRAF2_1	446	449	PF00917	0.369
LIG_TRAF2_1	53	56	PF00917	0.386
LIG_TYR_ITIM	479	484	PF00017	0.367
LIG_TYR_ITIM	88	93	PF00017	0.440
LIG_UBA3_1	211	219	PF00899	0.340
LIG_UBA3_1	306	311	PF00899	0.227
LIG_UBA3_1	606	613	PF00899	0.450
LIG_WRC_WIRS_1	350	355	PF05994	0.476
LIG_WRPW_2	363	366	PF00400	0.430
MOD_CDK_SPK_2	342	347	PF00069	0.359
MOD_CK1_1	166	172	PF00069	0.409
MOD_CK1_1	232	238	PF00069	0.486
MOD_CK1_1	276	282	PF00069	0.354
MOD_CK1_1	345	351	PF00069	0.276
MOD_CK1_1	39	45	PF00069	0.511
MOD_CK1_1	444	450	PF00069	0.362
MOD_CK1_1	51	57	PF00069	0.483
MOD_CK1_1	602	608	PF00069	0.544
MOD_CK1_1	70	76	PF00069	0.416
MOD_CK2_1	13	19	PF00069	0.482
MOD_CK2_1	148	154	PF00069	0.346
MOD_CK2_1	231	237	PF00069	0.419
MOD_CK2_1	258	264	PF00069	0.394
MOD_CK2_1	443	449	PF00069	0.386
MOD_CK2_1	50	56	PF00069	0.413
MOD_CK2_1	70	76	PF00069	0.494
MOD_Cter_Amidation	105	108	PF01082	0.544
MOD_Cter_Amidation	82	85	PF01082	0.476
MOD_GlcNHglycan	260	263	PF01048	0.343
MOD_GlcNHglycan	275	278	PF01048	0.333
MOD_GlcNHglycan	40	44	PF01048	0.504
MOD_GlcNHglycan	437	440	PF01048	0.338
MOD_GSK3_1	142	149	PF00069	0.503
MOD_GSK3_1	258	265	PF00069	0.367
MOD_GSK3_1	272	279	PF00069	0.346
MOD_GSK3_1	345	352	PF00069	0.368
MOD_GSK3_1	577	584	PF00069	0.429
MOD_GSK3_1	642	649	PF00069	0.366
MOD_N-GLC_1	200	205	PF02516	0.337
MOD_N-GLC_1	51	56	PF02516	0.424
MOD_N-GLC_1	551	556	PF02516	0.247
MOD_N-GLC_1	98	103	PF02516	0.594
MOD_N-GLC_2	410	412	PF02516	0.208
MOD_N-GLC_2	654	656	PF02516	0.341
MOD_N-GLC_2	77	79	PF02516	0.435
MOD_NEK2_1	172	177	PF00069	0.315
MOD_NEK2_1	190	195	PF00069	0.323
MOD_NEK2_1	273	278	PF00069	0.361
MOD_NEK2_1	297	302	PF00069	0.432
MOD_NEK2_1	328	333	PF00069	0.416
MOD_NEK2_1	349	354	PF00069	0.384
MOD_NEK2_1	443	448	PF00069	0.387
MOD_NEK2_1	464	469	PF00069	0.342
MOD_NEK2_1	577	582	PF00069	0.455
MOD_NEK2_1	646	651	PF00069	0.378
MOD_NEK2_2	160	165	PF00069	0.305
MOD_NEK2_2	551	556	PF00069	0.286
MOD_NMyristoyl	1	7	PF02799	0.395
MOD_OFUCOSY	162	167	PF10250	0.227
MOD_PIKK_1	166	172	PF00454	0.324
MOD_PIKK_1	190	196	PF00454	0.404
MOD_PIKK_1	297	303	PF00454	0.481
MOD_PIKK_1	444	450	PF00454	0.321
MOD_PKA_2	48	54	PF00069	0.447
MOD_PKA_2	654	660	PF00069	0.461
MOD_Plk_1	153	159	PF00069	0.323
MOD_Plk_1	30	36	PF00069	0.458
MOD_Plk_1	358	364	PF00069	0.299
MOD_Plk_1	585	591	PF00069	0.462
MOD_Plk_4	110	116	PF00069	0.445
MOD_Plk_4	148	154	PF00069	0.419
MOD_Plk_4	160	166	PF00069	0.286
MOD_Plk_4	173	179	PF00069	0.341
MOD_Plk_4	207	213	PF00069	0.318
MOD_Plk_4	288	294	PF00069	0.372
MOD_Plk_4	315	321	PF00069	0.381
MOD_Plk_4	329	335	PF00069	0.293
MOD_Plk_4	577	583	PF00069	0.356
MOD_Plk_4	70	76	PF00069	0.472
MOD_ProDKin_1	342	348	PF00069	0.349
MOD_ProDKin_1	411	417	PF00069	0.350
MOD_ProDKin_1	669	675	PF00069	0.445
MOD_SUMO_rev_2	377	387	PF00179	0.450
MOD_SUMO_rev_2	497	504	PF00179	0.332
MOD_SUMO_rev_2	51	61	PF00179	0.407
TRG_DiLeu_BaEn_4	56	62	PF01217	0.432
TRG_ENDOCYTIC_2	125	128	PF00928	0.344
TRG_ENDOCYTIC_2	178	181	PF00928	0.347
TRG_ENDOCYTIC_2	319	322	PF00928	0.281
TRG_ENDOCYTIC_2	357	360	PF00928	0.311
TRG_ENDOCYTIC_2	363	366	PF00928	0.274
TRG_ENDOCYTIC_2	434	437	PF00928	0.376
TRG_ENDOCYTIC_2	481	484	PF00928	0.319
TRG_ENDOCYTIC_2	572	575	PF00928	0.417
TRG_ENDOCYTIC_2	603	606	PF00928	0.494
TRG_ENDOCYTIC_2	693	696	PF00928	0.382
TRG_ENDOCYTIC_2	90	93	PF00928	0.414
TRG_ER_diArg_1	378	380	PF00400	0.314
TRG_ER_diArg_1	686	688	PF00400	0.435
TRG_NES_CRM1_1	449	460	PF08389	0.364
TRG_NLS_Bipartite_1	379	397	PF00514	0.301
TRG_NLS_Bipartite_1	91	111	PF00514	0.598
TRG_NLS_MonoExtC_3	106	112	PF00514	0.561
TRG_NLS_MonoExtC_3	392	398	PF00514	0.301
TRG_NLS_MonoExtC_3	58	64	PF00514	0.285
TRG_NLS_MonoExtN_4	683	689	PF00514	0.408
TRG_Pf-PMV_PEXEL_1	137	141	PF00026	0.359
TRG_Pf-PMV_PEXEL_1	347	351	PF00026	0.378
TRG_Pf-PMV_PEXEL_1	394	398	PF00026	0.267
TRG_Pf-PMV_PEXEL_1	665	669	PF00026	0.335
TRG_Pf-PMV_PEXEL_1	687	691	PF00026	0.402

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0H2ZF83	Pseudomonas aeruginosa (strain UCBPP-PA14)	23%	100%
A0A0N0P580	Leptomonas seymouri	45%	99%
A0A0N1I4E1	Leptomonas seymouri	20%	100%
A0A0N1IFY3	Leptomonas seymouri	23%	100%
A0A0N1IG93	Leptomonas seymouri	49%	100%
A0A0N1PBD0	Leptomonas seymouri	69%	100%
A0A0S4IKS1	Bodo saltans	44%	100%
A0A0S4ILZ2	Bodo saltans	41%	99%
A0A1X0NN84	Trypanosomatidae	23%	100%
A0A1X0P2Q8	Trypanosomatidae	46%	100%
A0A1X0P2W9	Trypanosomatidae	46%	100%
A0A1X0P3Q5	Trypanosomatidae	49%	100%
A0A1X0P428	Trypanosomatidae	48%	100%
A0A1X0P8N7	Trypanosomatidae	58%	100%
A0A2H5AIX5	Narcissus pseudonarcissus	23%	100%
A0A3Q8I9I3	Leishmania donovani	22%	100%
A0A3R7KCI7	Trypanosoma rangeli	46%	100%
A0A3R7M7X9	Trypanosoma rangeli	46%	100%
A0A3R7N023	Trypanosoma rangeli	48%	100%
A0A3S5H4V6	Leishmania donovani	47%	98%
A0A3S7WVG2	Leishmania donovani	22%	100%
A0A3S7WVL1	Leishmania donovani	22%	100%
A0A422NFF5	Trypanosoma rangeli	50%	100%
A0A422NQH3	Trypanosoma rangeli	55%	100%
A0A451EJA3	Leishmania donovani	45%	100%
A0A451EJA5	Leishmania donovani	47%	100%
A0A451EJA6	Leishmania donovani	44%	100%
A0A451EJM7	Leishmania donovani	99%	100%
A1L1K7	Rattus norvegicus	25%	100%
A4H373	Leishmania braziliensis	45%	99%
A4H374	Leishmania braziliensis	47%	99%
A4H375	Leishmania braziliensis	48%	100%
A4H376	Leishmania braziliensis	31%	100%
A4H3J5	Leishmania braziliensis	77%	100%
A4H731	Leishmania braziliensis	21%	100%
A4HRH0	Leishmania infantum	45%	99%
A4HRH2	Leishmania infantum	47%	99%
A4HRH3	Leishmania infantum	44%	100%
A4HRH5	Leishmania infantum	47%	100%
A4HVG5	Leishmania infantum	22%	100%
A4HYA8	Leishmania infantum	22%	100%
A4WE11	Enterobacter sp. (strain 638)	22%	98%
A4YDR9	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	23%	100%
A6TDH2	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	22%	98%
A7ZHC8	Escherichia coli O139:H28 (strain E24377A / ETEC)	21%	100%
A7ZVY7	Escherichia coli O9:H4 (strain HS)	21%	100%
A9MYJ6	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	21%	100%
B1IRD9	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	21%	100%
B2HGV4	Mycobacterium marinum (strain ATCC BAA-535 / M)	24%	100%
B4T6J6	Salmonella newport (strain SL254)	22%	100%
B4TIH0	Salmonella heidelberg (strain SL476)	22%	100%
B4TWR4	Salmonella schwarzengrund (strain CVM19633)	22%	100%
B5BL55	Salmonella paratyphi A (strain AKU_12601)	22%	100%
B5F750	Salmonella agona (strain SL483)	22%	100%
B5FHG5	Salmonella dublin (strain CT_02021853)	22%	100%
B5R1R0	Salmonella enteritidis PT4 (strain P125109)	22%	100%
B5XUP2	Klebsiella pneumoniae (strain 342)	23%	98%
B6HYY8	Escherichia coli (strain SE11)	21%	100%
B7L4G0	Escherichia coli (strain 55989 / EAEC)	21%	100%
B7LWM8	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	21%	100%
B7M0D4	Escherichia coli O8 (strain IAI1)	21%	100%
B7MNP4	Escherichia coli O81 (strain ED1a)	20%	100%
B7UI83	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	21%	100%
C0Q4L3	Salmonella paratyphi C (strain RKS4594)	22%	100%
C1D6V9	Laribacter hongkongensis (strain HLHK9)	23%	100%
C5D6U5	Geobacillus sp. (strain WCH70)	23%	100%
C9ZXK0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	100%
C9ZXK1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	99%
C9ZXK2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	100%
C9ZXK3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	100%
D0A233	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	100%
E9AC38	Leishmania major	46%	99%
E9AC40	Leishmania major	46%	99%
E9AC41	Leishmania major	45%	100%
E9AC43	Leishmania major	47%	100%
E9ACH0	Leishmania major	93%	100%
E9AGS5	Leishmania infantum	22%	97%
E9AGS6	Leishmania infantum	22%	100%
E9AJD4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	99%
E9AJD6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	47%	99%
E9AJD7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	100%
E9AJD9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	100%
E9AJQ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
E9AP66	Leishmania mexicana (strain MHOM/GT/2001/U1103)	22%	100%
E9AS49	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9AS50	Leishmania mexicana (strain MHOM/GT/2001/U1103)	22%	100%
M4ISH0	Humulus lupulus	23%	100%
M4ISH1	Humulus lupulus	27%	100%
O22898	Arabidopsis thaliana	28%	100%
O24146	Nicotiana tabacum	23%	100%
O24540	Vanilla planifolia	23%	100%
O31826	Bacillus subtilis (strain 168)	23%	100%
O35547	Rattus norvegicus	30%	99%
O53521	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	24%	100%
O60135	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	29%	100%
O60488	Homo sapiens	31%	99%
O88813	Rattus norvegicus	29%	100%
O95573	Homo sapiens	31%	98%
P08659	Photinus pyralis	23%	100%
P14912	Petroselinum crispum	23%	100%
P14913	Petroselinum crispum	23%	100%
P16405	Plasmodium falciparum (isolate NF7 / Ghana)	25%	100%
P18163	Rattus norvegicus	28%	100%
P30624	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	100%
P33121	Homo sapiens	28%	100%
P33124	Rattus norvegicus	28%	100%
P39002	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	100%
P39518	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	95%
P41216	Mus musculus	29%	100%
P44446	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	25%	100%
P47912	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	100%
P63521	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	22%	100%
P63522	Salmonella typhi	22%	100%
P94547	Bacillus subtilis (strain 168)	22%	100%
P9WEY3	Penicillium brevicompactum	27%	100%
P9WQ36	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	23%	100%
P9WQ37	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	23%	100%
Q00594	Pseudomonas oleovorans	21%	100%
Q04P35	Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)	22%	100%
Q056J9	Leptospira borgpetersenii serovar Hardjo-bovis (strain L550)	23%	100%
Q0P4F7	Danio rerio	23%	100%
Q0T8F7	Shigella flexneri serotype 5b (strain 8401)	21%	100%
Q17577	Caenorhabditis elegans	22%	100%
Q17QJ1	Bos taurus	23%	100%
Q1ZXQ4	Dictyostelium discoideum	29%	100%
Q2KHW5	Bos taurus	24%	97%
Q2UB01	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	22%	100%
Q2XU92	Mus musculus	25%	100%
Q32K60	Shigella dysenteriae serotype 1 (strain Sd197)	21%	100%
Q3URE1	Mus musculus	23%	100%
Q3Z5X2	Shigella sonnei (strain Ss046)	21%	100%
Q4QDB5	Leishmania major	24%	100%
Q4QGB2	Leishmania major	22%	100%
Q4R4P9	Macaca fascicularis	23%	97%
Q4WR83	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	25%	100%
Q55DR6	Dictyostelium discoideum	30%	100%
Q57TJ0	Salmonella choleraesuis (strain SC-B67)	22%	100%
Q5FVE4	Homo sapiens	22%	100%
Q5PIL0	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	22%	100%
Q5R668	Pongo abelii	31%	98%
Q5R9G9	Pongo abelii	21%	100%
Q5SKN9	Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)	23%	100%
Q5ZKR7	Gallus gallus	24%	92%
Q63151	Rattus norvegicus	31%	98%
Q72LY9	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	24%	100%
Q7TYX8	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	24%	100%
Q7WSH3	Comamonas testosteroni	27%	100%
Q7X279	Streptomyces sp.	23%	100%
Q7ZYC4	Xenopus laevis	25%	95%
Q83MG9	Shigella flexneri	21%	100%
Q84P21	Arabidopsis thaliana	26%	100%
Q84P25	Arabidopsis thaliana	23%	100%
Q84P26	Arabidopsis thaliana	24%	100%
Q8EYG2	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	24%	100%
Q8H151	Arabidopsis thaliana	22%	100%
Q8JZR0	Mus musculus	29%	100%
Q8LKS5	Arabidopsis thaliana	32%	100%
Q8LPS1	Arabidopsis thaliana	32%	100%
Q8VCW8	Mus musculus	22%	100%
Q8W471	Arabidopsis thaliana	25%	97%
Q8Z9L4	Salmonella typhi	22%	100%
Q8ZES9	Yersinia pestis	23%	100%
Q8ZRX4	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	22%	100%
Q91WC3	Mus musculus	27%	100%
Q924N5	Rattus norvegicus	23%	98%
Q96GR2	Homo sapiens	23%	97%
Q99PU5	Mus musculus	23%	98%
Q9C7W4	Arabidopsis thaliana	28%	100%
Q9C8D4	Arabidopsis thaliana	21%	100%
Q9CAP8	Arabidopsis thaliana	32%	100%
Q9CZW4	Mus musculus	30%	98%
Q9EY88	Amycolatopsis sp.	23%	100%
Q9HWG3	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	23%	100%
Q9JID6	Cavia porcellus	30%	100%
Q9LK39	Arabidopsis thaliana	24%	98%
Q9LPK6	Arabidopsis thaliana	22%	100%
Q9LQ12	Arabidopsis thaliana	22%	100%
Q9P7D7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	100%
Q9QUJ7	Mus musculus	30%	99%
Q9SJD4	Arabidopsis thaliana	32%	98%
Q9SS01	Arabidopsis thaliana	21%	100%
Q9T009	Arabidopsis thaliana	30%	100%
Q9T0A0	Arabidopsis thaliana	28%	100%
Q9UKU0	Homo sapiens	27%	100%
Q9ULC5	Homo sapiens	29%	100%
Q9V3S9	Drosophila melanogaster	24%	100%
Q9V3U0	Drosophila melanogaster	23%	100%
Q9XIA9	Arabidopsis thaliana	27%	100%
S5M744	Streptomyces sp.	23%	100%
V5AX22	Trypanosoma cruzi	50%	100%
V5AZ02	Trypanosoma cruzi	55%	100%
V5BCF5	Trypanosoma cruzi	49%	99%
V5BH13	Trypanosoma cruzi	45%	100%
V5BLJ2	Trypanosoma cruzi	47%	100%
V5D9X5	Trypanosoma cruzi	21%	100%
W6R1D9	Penicillium roqueforti (strain FM164)	27%	100%
W7L9F0	Gibberella moniliformis (strain M3125 / FGSC 7600)	30%	100%