Dehydrogenase/oxidoreductase-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

dehydrogenase/oxidoreductase-like protein

Species:

Leishmania infantum

UniProt:

A4HRR8_LEIIN

TriTrypDb:

LINF_020012460

Length:

181

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HRR8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HRR8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	134	140	PF00089	0.555
CLV_NRD_NRD_1	103	105	PF00675	0.531
CLV_NRD_NRD_1	127	129	PF00675	0.694
CLV_NRD_NRD_1	161	163	PF00675	0.432
CLV_PCSK_KEX2_1	103	105	PF00082	0.530
CLV_PCSK_KEX2_1	127	129	PF00082	0.694
CLV_PCSK_KEX2_1	161	163	PF00082	0.432
DEG_SPOP_SBC_1	144	148	PF00917	0.548
DOC_MAPK_gen_1	161	168	PF00069	0.398
DOC_MAPK_HePTP_8	158	170	PF00069	0.395
DOC_MAPK_MEF2A_6	161	170	PF00069	0.390
DOC_MAPK_MEF2A_6	24	31	PF00069	0.386
DOC_MAPK_NFAT4_5	24	32	PF00069	0.387
DOC_PP1_RVXF_1	165	171	PF00149	0.360
DOC_PP4_FxxP_1	172	175	PF00568	0.375
DOC_USP7_MATH_1	145	149	PF00917	0.533
DOC_WW_Pin1_4	108	113	PF00397	0.576
DOC_WW_Pin1_4	146	151	PF00397	0.598
DOC_WW_Pin1_4	45	50	PF00397	0.558
DOC_WW_Pin1_4	52	57	PF00397	0.561
LIG_14-3-3_CanoR_1	104	113	PF00244	0.623
LIG_APCC_ABBAyCdc20_2	103	109	PF00400	0.555
LIG_BIR_III_2	18	22	PF00653	0.532
LIG_CtBP_PxDLS_1	62	66	PF00389	0.578
LIG_FHA_1	175	181	PF00498	0.423
LIG_FHA_1	79	85	PF00498	0.545
LIG_SH3_3	147	153	PF00018	0.499
MOD_CK1_1	108	114	PF00069	0.582
MOD_CK1_1	122	128	PF00069	0.522
MOD_CK1_1	146	152	PF00069	0.513
MOD_CK1_1	173	179	PF00069	0.390
MOD_CK1_1	85	91	PF00069	0.582
MOD_CK2_1	118	124	PF00069	0.586
MOD_Cter_Amidation	125	128	PF01082	0.582
MOD_GlcNHglycan	10	13	PF01048	0.449
MOD_GSK3_1	114	121	PF00069	0.634
MOD_GSK3_1	170	177	PF00069	0.378
MOD_GSK3_1	4	11	PF00069	0.483
MOD_GSK3_1	78	85	PF00069	0.548
MOD_GSK3_1	86	93	PF00069	0.447
MOD_N-GLC_2	35	37	PF02516	0.371
MOD_NEK2_1	170	175	PF00069	0.371
MOD_NEK2_1	23	28	PF00069	0.322
MOD_NEK2_1	4	9	PF00069	0.605
MOD_PKA_1	161	167	PF00069	0.404
MOD_PKA_2	161	167	PF00069	0.404
MOD_PKA_2	23	29	PF00069	0.326
MOD_PKA_2	4	10	PF00069	0.599
MOD_PKA_2	90	96	PF00069	0.578
MOD_Plk_1	5	11	PF00069	0.476
MOD_Plk_4	82	88	PF00069	0.528
MOD_ProDKin_1	108	114	PF00069	0.576
MOD_ProDKin_1	146	152	PF00069	0.590
MOD_ProDKin_1	45	51	PF00069	0.561
MOD_ProDKin_1	52	58	PF00069	0.556
TRG_ER_diArg_1	160	162	PF00400	0.413
TRG_Pf-PMV_PEXEL_1	104	109	PF00026	0.558

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H517	Leishmania donovani	99%	100%
E9ACE7	Leishmania major	78%	100%
E9ACX6	Leishmania major	78%	100%