Tautomerase_3 domain-containing protein

Quick info Annotations Localization Phosphorylation Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HRQ0_LEIIN

TriTrypDb:

LINF_020010800

Length:

163

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 4
Forrest at al. (procyclic)	yes	yes: 8
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 30

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 24

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 20
NetGPI	no	yes: 0, no: 20

Could not find GO cellular_component term for this entry.

Phosphorylation

Promastigote/Amastigote: 59, 64

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4HRQ0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HRQ0

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	25	29	PF00656	0.494
CLV_PCSK_SKI1_1	52	56	PF00082	0.477
DOC_CYCLIN_RxL_1	46	59	PF00134	0.628
DOC_MAPK_gen_1	104	113	PF00069	0.375
DOC_MAPK_gen_1	151	160	PF00069	0.525
DOC_MAPK_MEF2A_6	123	130	PF00069	0.389
DOC_MAPK_NFAT4_5	123	131	PF00069	0.405
DOC_PP4_FxxP_1	10	13	PF00568	0.375
DOC_USP7_MATH_1	13	17	PF00917	0.308
DOC_USP7_MATH_1	90	94	PF00917	0.576

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2D0	Leptomonas seymouri	64%	100%
A0A0N1HW96	Leptomonas seymouri	29%	100%
A0A0S4IPF2	Bodo saltans	30%	100%
A0A0S4JFI1	Bodo saltans	35%	100%
A0A1X0NKC2	Trypanosomatidae	34%	100%
A0A1X0P259	Trypanosomatidae	31%	100%
A0A3R7K0R9	Trypanosoma rangeli	29%	100%
A0A3S5H506	Leishmania donovani	100%	100%
A0A3S7X3W3	Leishmania donovani	29%	100%
A0A422NFX4	Trypanosoma rangeli	38%	100%

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