Ribosome biogenesis protein SLX9

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HRP3_LEIIN

TriTrypDb:

LINF_020010000

Length:

201

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HRP3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HRP3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	100	102	PF00675	0.804
CLV_NRD_NRD_1	121	123	PF00675	0.597
CLV_NRD_NRD_1	129	131	PF00675	0.606
CLV_NRD_NRD_1	18	20	PF00675	0.655
CLV_NRD_NRD_1	199	201	PF00675	0.689
CLV_PCSK_KEX2_1	100	102	PF00082	0.704
CLV_PCSK_KEX2_1	121	123	PF00082	0.597
CLV_PCSK_KEX2_1	128	130	PF00082	0.601
CLV_PCSK_KEX2_1	18	20	PF00082	0.654
CLV_PCSK_KEX2_1	198	200	PF00082	0.747
CLV_PCSK_KEX2_1	8	10	PF00082	0.647
CLV_PCSK_PC1ET2_1	100	102	PF00082	0.704
CLV_PCSK_PC1ET2_1	8	10	PF00082	0.647
CLV_PCSK_SKI1_1	121	125	PF00082	0.607
CLV_PCSK_SKI1_1	129	133	PF00082	0.565
CLV_PCSK_SKI1_1	66	70	PF00082	0.563
CLV_PCSK_SKI1_1	8	12	PF00082	0.576
DEG_APCC_DBOX_1	129	137	PF00400	0.712
DEG_SPOP_SBC_1	30	34	PF00917	0.712
DOC_CKS1_1	183	188	PF01111	0.624
DOC_MAPK_gen_1	75	84	PF00069	0.723
DOC_MAPK_RevD_3	186	199	PF00069	0.618
DOC_PP2B_LxvP_1	131	134	PF13499	0.618
DOC_USP7_MATH_1	134	138	PF00917	0.630
DOC_USP7_MATH_1	31	35	PF00917	0.699
DOC_USP7_UBL2_3	11	15	PF12436	0.658
DOC_WW_Pin1_4	182	187	PF00397	0.616
DOC_WW_Pin1_4	36	41	PF00397	0.762
LIG_14-3-3_CanoR_1	121	126	PF00244	0.689
LIG_14-3-3_CanoR_1	128	134	PF00244	0.663
LIG_14-3-3_CanoR_1	135	143	PF00244	0.521
LIG_14-3-3_CanoR_1	91	97	PF00244	0.745
LIG_AP2alpha_2	165	167	PF02296	0.550
LIG_BIR_II_1	1	5	PF00653	0.681
LIG_FHA_1	115	121	PF00498	0.621
LIG_FHA_1	175	181	PF00498	0.528
LIG_FHA_1	183	189	PF00498	0.559
LIG_FHA_2	122	128	PF00498	0.530
LIG_FHA_2	53	59	PF00498	0.656
LIG_LIR_Gen_1	164	174	PF02991	0.543
LIG_LIR_Nem_3	164	170	PF02991	0.537
LIG_RPA_C_Fungi	117	129	PF08784	0.609
LIG_SH3_3	177	183	PF00018	0.676
LIG_SH3_4	111	118	PF00018	0.664
LIG_TRAF2_1	146	149	PF00917	0.511
MOD_CK1_1	114	120	PF00069	0.720
MOD_CK1_1	34	40	PF00069	0.731
MOD_CK2_1	121	127	PF00069	0.628
MOD_CK2_1	134	140	PF00069	0.573
MOD_GlcNHglycan	136	139	PF01048	0.567
MOD_GlcNHglycan	174	177	PF01048	0.571
MOD_GlcNHglycan	33	36	PF01048	0.739
MOD_GSK3_1	110	117	PF00069	0.761
MOD_GSK3_1	134	141	PF00069	0.574
MOD_GSK3_1	19	26	PF00069	0.716
MOD_GSK3_1	30	37	PF00069	0.705
MOD_PIKK_1	111	117	PF00454	0.743
MOD_PIKK_1	19	25	PF00454	0.631
MOD_PKA_1	121	127	PF00069	0.604
MOD_PKA_1	129	135	PF00069	0.586
MOD_PKA_2	121	127	PF00069	0.686
MOD_PKA_2	129	135	PF00069	0.586
MOD_PKA_2	141	147	PF00069	0.323
MOD_PKA_2	90	96	PF00069	0.791
MOD_Plk_4	121	127	PF00069	0.686
MOD_ProDKin_1	182	188	PF00069	0.619
MOD_ProDKin_1	36	42	PF00069	0.761
TRG_ER_diArg_1	120	122	PF00400	0.605
TRG_ER_diArg_1	128	130	PF00400	0.601
TRG_ER_diArg_1	198	200	PF00400	0.708
TRG_ER_diArg_1	69	72	PF00400	0.621
TRG_NLS_MonoExtN_4	5	12	PF00514	0.749

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P478	Leptomonas seymouri	52%	92%
A0A451EJI4	Leishmania donovani	100%	100%
A4H3D9	Leishmania braziliensis	60%	100%
E9ACC2	Leishmania major	91%	100%
E9AJL0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%