Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HRM4_LEIIN

TriTrypDb:

LINF_020007700

Length:

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HRM4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HRM4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	35	37	PF00675	0.563
CLV_PCSK_KEX2_1	35	37	PF00082	0.651
CLV_PCSK_KEX2_1	60	62	PF00082	0.624
CLV_PCSK_PC1ET2_1	60	62	PF00082	0.624
DEG_Nend_Nbox_1	1	3	PF02207	0.665
LIG_14-3-3_CterR_2	61	64	PF00244	0.655
LIG_LIR_Gen_1	22	30	PF02991	0.521
LIG_LIR_Gen_1	38	46	PF02991	0.455
LIG_LIR_Nem_3	22	28	PF02991	0.519
LIG_LIR_Nem_3	38	42	PF02991	0.462
LIG_Pex14_2	42	46	PF04695	0.623
LIG_Pex14_2	5	9	PF04695	0.617
LIG_SH2_STAP1	25	29	PF00017	0.678
MOD_Cter_Amidation	58	61	PF01082	0.517
MOD_NEK2_1	24	29	PF00069	0.553
MOD_Plk_4	24	30	PF00069	0.678
TRG_DiLeu_BaEn_2	37	43	PF01217	0.553
TRG_ENDOCYTIC_2	25	28	PF00928	0.524

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H4Z3	Leishmania donovani	100%	100%
A4H3C3	Leishmania braziliensis	84%	100%
E9ACA2	Leishmania major	98%	100%
E9AJJ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%