LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Phosphoglycan beta 1,3 galactosyltransferase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Phosphoglycan beta 1,3 galactosyltransferase
Gene product:
phosphoglycan beta 1 -3 galactosyltransferase
Species:
Leishmania infantum
UniProt:
A4HRM0_LEIIN
TriTrypDb:
LINF_020006800 *
Length:
737

Annotations

LeishMANIAdb annotations

Phosphoglycan beta 1,3 galactosyltransferase (required for proper protective coat formation). Probably part of a much larger group. Expanded in Leishmaniids. Localization: Golgi (by homology)

Annotations by Jardim et al.

Glycosylation, Phosphoglycan beta 1,3 galactosyltransferase SCGR5

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 60
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 16
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 52
NetGPI no yes: 0, no: 52
Cellular components
Term Name Level Count
GO:0016020 membrane 2 53
GO:0110165 cellular anatomical entity 1 53
GO:0000139 Golgi membrane 5 13
GO:0031090 organelle membrane 3 13
GO:0098588 bounding membrane of organelle 4 13

Expansion

Sequence features

A4HRM0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HRM0

Function

Biological processes
Term Name Level Count
GO:0006486 protein glycosylation 4 53
GO:0006807 nitrogen compound metabolic process 2 53
GO:0008152 metabolic process 1 53
GO:0019538 protein metabolic process 3 53
GO:0036211 protein modification process 4 53
GO:0043170 macromolecule metabolic process 3 53
GO:0043412 macromolecule modification 4 53
GO:0043413 macromolecule glycosylation 3 53
GO:0044238 primary metabolic process 2 53
GO:0070085 glycosylation 2 53
GO:0071704 organic substance metabolic process 2 53
GO:1901564 organonitrogen compound metabolic process 3 53
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 53
GO:0016740 transferase activity 2 53
GO:0016757 glycosyltransferase activity 3 53
GO:0016758 hexosyltransferase activity 4 53
GO:0008194 UDP-glycosyltransferase activity 4 13

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 11 13 PF00675 0.514
CLV_NRD_NRD_1 15 17 PF00675 0.503
CLV_NRD_NRD_1 233 235 PF00675 0.569
CLV_NRD_NRD_1 332 334 PF00675 0.707
CLV_NRD_NRD_1 416 418 PF00675 0.733
CLV_NRD_NRD_1 484 486 PF00675 0.604
CLV_NRD_NRD_1 516 518 PF00675 0.522
CLV_NRD_NRD_1 56 58 PF00675 0.631
CLV_NRD_NRD_1 655 657 PF00675 0.562
CLV_NRD_NRD_1 676 678 PF00675 0.559
CLV_NRD_NRD_1 87 89 PF00675 0.569
CLV_PCSK_KEX2_1 10 12 PF00082 0.533
CLV_PCSK_KEX2_1 17 19 PF00082 0.496
CLV_PCSK_KEX2_1 233 235 PF00082 0.572
CLV_PCSK_KEX2_1 331 333 PF00082 0.705
CLV_PCSK_KEX2_1 416 418 PF00082 0.661
CLV_PCSK_KEX2_1 44 46 PF00082 0.651
CLV_PCSK_KEX2_1 486 488 PF00082 0.596
CLV_PCSK_KEX2_1 516 518 PF00082 0.529
CLV_PCSK_KEX2_1 56 58 PF00082 0.585
CLV_PCSK_KEX2_1 589 591 PF00082 0.624
CLV_PCSK_KEX2_1 655 657 PF00082 0.622
CLV_PCSK_KEX2_1 675 677 PF00082 0.567
CLV_PCSK_KEX2_1 699 701 PF00082 0.604
CLV_PCSK_KEX2_1 725 727 PF00082 0.565
CLV_PCSK_KEX2_1 87 89 PF00082 0.569
CLV_PCSK_PC1ET2_1 17 19 PF00082 0.454
CLV_PCSK_PC1ET2_1 44 46 PF00082 0.615
CLV_PCSK_PC1ET2_1 486 488 PF00082 0.562
CLV_PCSK_PC1ET2_1 589 591 PF00082 0.543
CLV_PCSK_PC1ET2_1 655 657 PF00082 0.622
CLV_PCSK_PC1ET2_1 675 677 PF00082 0.537
CLV_PCSK_PC1ET2_1 699 701 PF00082 0.586
CLV_PCSK_PC1ET2_1 725 727 PF00082 0.527
CLV_PCSK_PC7_1 229 235 PF00082 0.541
CLV_PCSK_PC7_1 585 591 PF00082 0.537
CLV_PCSK_PC7_1 7 13 PF00082 0.458
CLV_PCSK_SKI1_1 225 229 PF00082 0.598
CLV_PCSK_SKI1_1 298 302 PF00082 0.586
CLV_PCSK_SKI1_1 333 337 PF00082 0.619
CLV_PCSK_SKI1_1 41 45 PF00082 0.603
CLV_PCSK_SKI1_1 441 445 PF00082 0.619
CLV_PCSK_SKI1_1 571 575 PF00082 0.501
CLV_PCSK_SKI1_1 718 722 PF00082 0.534
CLV_Separin_Metazoa 280 284 PF03568 0.463
DEG_Nend_UBRbox_1 1 4 PF02207 0.618
DEG_SCF_FBW7_1 377 384 PF00400 0.501
DOC_CKS1_1 207 212 PF01111 0.358
DOC_CKS1_1 268 273 PF01111 0.464
DOC_CKS1_1 378 383 PF01111 0.503
DOC_CYCLIN_RxL_1 370 380 PF00134 0.313
DOC_CYCLIN_yCln2_LP_2 375 381 PF00134 0.542
DOC_CYCLIN_yCln2_LP_2 61 67 PF00134 0.397
DOC_MAPK_gen_1 16 24 PF00069 0.693
DOC_MAPK_gen_1 516 524 PF00069 0.314
DOC_MAPK_JIP1_4 18 24 PF00069 0.483
DOC_MAPK_MEF2A_6 159 167 PF00069 0.388
DOC_MAPK_MEF2A_6 16 24 PF00069 0.729
DOC_MAPK_MEF2A_6 405 412 PF00069 0.474
DOC_MAPK_MEF2A_6 90 99 PF00069 0.396
DOC_PP1_RVXF_1 403 410 PF00149 0.360
DOC_PP1_RVXF_1 439 446 PF00149 0.461
DOC_PP2B_LxvP_1 375 378 PF13499 0.544
DOC_PP4_FxxP_1 383 386 PF00568 0.402
DOC_USP7_MATH_1 151 155 PF00917 0.536
DOC_USP7_MATH_1 166 170 PF00917 0.400
DOC_USP7_MATH_1 264 268 PF00917 0.445
DOC_USP7_MATH_1 316 320 PF00917 0.410
DOC_USP7_MATH_1 335 339 PF00917 0.324
DOC_USP7_MATH_1 95 99 PF00917 0.404
DOC_USP7_UBL2_3 721 725 PF12436 0.320
DOC_WW_Pin1_4 106 111 PF00397 0.387
DOC_WW_Pin1_4 206 211 PF00397 0.398
DOC_WW_Pin1_4 267 272 PF00397 0.476
DOC_WW_Pin1_4 345 350 PF00397 0.517
DOC_WW_Pin1_4 362 367 PF00397 0.462
DOC_WW_Pin1_4 377 382 PF00397 0.471
DOC_WW_Pin1_4 629 634 PF00397 0.329
DOC_WW_Pin1_4 698 703 PF00397 0.368
LIG_14-3-3_CanoR_1 131 138 PF00244 0.457
LIG_14-3-3_CanoR_1 233 237 PF00244 0.498
LIG_14-3-3_CanoR_1 337 341 PF00244 0.372
LIG_14-3-3_CanoR_1 373 378 PF00244 0.325
LIG_14-3-3_CanoR_1 516 520 PF00244 0.309
LIG_14-3-3_CanoR_1 571 580 PF00244 0.312
LIG_14-3-3_CanoR_1 676 684 PF00244 0.383
LIG_Actin_WH2_2 173 189 PF00022 0.402
LIG_Actin_WH2_2 322 339 PF00022 0.352
LIG_EH1_1 529 537 PF00400 0.273
LIG_eIF4E_1 29 35 PF01652 0.268
LIG_FHA_1 115 121 PF00498 0.561
LIG_FHA_1 169 175 PF00498 0.529
LIG_FHA_1 207 213 PF00498 0.358
LIG_FHA_1 34 40 PF00498 0.341
LIG_FHA_1 363 369 PF00498 0.454
LIG_FHA_1 527 533 PF00498 0.308
LIG_FHA_1 78 84 PF00498 0.401
LIG_FHA_2 236 242 PF00498 0.436
LIG_FHA_2 275 281 PF00498 0.475
LIG_FHA_2 421 427 PF00498 0.388
LIG_FHA_2 572 578 PF00498 0.301
LIG_FHA_2 630 636 PF00498 0.312
LIG_FHA_2 677 683 PF00498 0.367
LIG_FHA_2 686 692 PF00498 0.319
LIG_GBD_Chelix_1 26 34 PF00786 0.247
LIG_IRF3_LxIS_1 24 31 PF10401 0.241
LIG_LIR_Apic_2 380 386 PF02991 0.401
LIG_LIR_Gen_1 209 218 PF02991 0.353
LIG_LIR_Gen_1 238 243 PF02991 0.347
LIG_LIR_Gen_1 447 458 PF02991 0.384
LIG_LIR_Gen_1 464 474 PF02991 0.382
LIG_LIR_Gen_1 605 613 PF02991 0.366
LIG_LIR_Gen_1 62 69 PF02991 0.486
LIG_LIR_Gen_1 622 628 PF02991 0.384
LIG_LIR_Nem_3 209 214 PF02991 0.342
LIG_LIR_Nem_3 235 239 PF02991 0.499
LIG_LIR_Nem_3 304 308 PF02991 0.361
LIG_LIR_Nem_3 36 40 PF02991 0.266
LIG_LIR_Nem_3 447 453 PF02991 0.434
LIG_LIR_Nem_3 464 470 PF02991 0.344
LIG_LIR_Nem_3 605 610 PF02991 0.368
LIG_LIR_Nem_3 62 68 PF02991 0.488
LIG_LIR_Nem_3 622 626 PF02991 0.389
LIG_LIR_Nem_3 635 639 PF02991 0.299
LIG_NRBOX 579 585 PF00104 0.308
LIG_REV1ctd_RIR_1 640 649 PF16727 0.307
LIG_SH2_CRK 467 471 PF00017 0.270
LIG_SH2_GRB2like 715 718 PF00017 0.327
LIG_SH2_NCK_1 308 312 PF00017 0.433
LIG_SH2_SRC 239 242 PF00017 0.364
LIG_SH2_SRC 448 451 PF00017 0.391
LIG_SH2_SRC 638 641 PF00017 0.293
LIG_SH2_STAP1 448 452 PF00017 0.481
LIG_SH2_STAP1 501 505 PF00017 0.334
LIG_SH2_STAT5 211 214 PF00017 0.409
LIG_SH2_STAT5 257 260 PF00017 0.445
LIG_SH2_STAT5 29 32 PF00017 0.289
LIG_SH2_STAT5 370 373 PF00017 0.404
LIG_SH2_STAT5 389 392 PF00017 0.355
LIG_SH2_STAT5 479 482 PF00017 0.394
LIG_SH2_STAT5 602 605 PF00017 0.374
LIG_SH2_STAT5 638 641 PF00017 0.467
LIG_SH2_STAT5 719 722 PF00017 0.342
LIG_SH3_3 204 210 PF00018 0.470
LIG_SH3_3 343 349 PF00018 0.351
LIG_SH3_3 375 381 PF00018 0.514
LIG_SH3_3 485 491 PF00018 0.373
LIG_SH3_3 537 543 PF00018 0.352
LIG_SH3_3 731 737 PF00018 0.305
LIG_SUMO_SIM_anti_2 551 556 PF11976 0.334
LIG_SUMO_SIM_par_1 551 556 PF11976 0.355
LIG_TRAF2_1 238 241 PF00917 0.374
LIG_TYR_ITIM 237 242 PF00017 0.570
LIG_TYR_ITSM 207 214 PF00017 0.405
LIG_UBA3_1 39 44 PF00899 0.438
LIG_WRC_WIRS_1 302 307 PF05994 0.388
MOD_CDK_SPxxK_3 345 352 PF00069 0.355
MOD_CK1_1 267 273 PF00069 0.720
MOD_CK1_1 309 315 PF00069 0.386
MOD_CK1_1 515 521 PF00069 0.352
MOD_CK2_1 133 139 PF00069 0.532
MOD_CK2_1 235 241 PF00069 0.516
MOD_CK2_1 274 280 PF00069 0.590
MOD_CK2_1 301 307 PF00069 0.662
MOD_CK2_1 354 360 PF00069 0.414
MOD_CK2_1 382 388 PF00069 0.469
MOD_CK2_1 655 661 PF00069 0.502
MOD_CK2_1 676 682 PF00069 0.392
MOD_CK2_1 685 691 PF00069 0.365
MOD_GlcNHglycan 135 138 PF01048 0.645
MOD_GlcNHglycan 153 156 PF01048 0.657
MOD_GlcNHglycan 290 293 PF01048 0.461
MOD_GlcNHglycan 298 301 PF01048 0.482
MOD_GlcNHglycan 307 311 PF01048 0.418
MOD_GlcNHglycan 318 321 PF01048 0.476
MOD_GlcNHglycan 394 397 PF01048 0.572
MOD_GlcNHglycan 481 484 PF01048 0.397
MOD_GlcNHglycan 498 501 PF01048 0.468
MOD_GlcNHglycan 92 95 PF01048 0.483
MOD_GSK3_1 102 109 PF00069 0.503
MOD_GSK3_1 126 133 PF00069 0.571
MOD_GSK3_1 362 369 PF00069 0.519
MOD_GSK3_1 373 380 PF00069 0.509
MOD_GSK3_1 416 423 PF00069 0.443
MOD_GSK3_1 43 50 PF00069 0.501
MOD_GSK3_1 567 574 PF00069 0.341
MOD_GSK3_1 647 654 PF00069 0.416
MOD_N-GLC_1 102 107 PF02516 0.448
MOD_N-GLC_1 288 293 PF02516 0.521
MOD_N-GLC_1 296 301 PF02516 0.417
MOD_N-GLC_1 420 425 PF02516 0.450
MOD_N-GLC_1 505 510 PF02516 0.337
MOD_N-GLC_1 545 550 PF02516 0.414
MOD_N-GLC_1 619 624 PF02516 0.361
MOD_NEK2_1 165 170 PF00069 0.460
MOD_NEK2_1 28 33 PF00069 0.391
MOD_NEK2_1 3 8 PF00069 0.508
MOD_NEK2_1 336 341 PF00069 0.361
MOD_NEK2_1 43 48 PF00069 0.463
MOD_NEK2_1 545 550 PF00069 0.501
MOD_NEK2_1 647 652 PF00069 0.378
MOD_NEK2_2 114 119 PF00069 0.706
MOD_PIKK_1 309 315 PF00454 0.396
MOD_PIKK_1 436 442 PF00454 0.577
MOD_PIKK_1 545 551 PF00454 0.399
MOD_PKA_1 416 422 PF00069 0.685
MOD_PKA_1 655 661 PF00069 0.381
MOD_PKA_1 675 681 PF00069 0.408
MOD_PKA_2 130 136 PF00069 0.578
MOD_PKA_2 232 238 PF00069 0.610
MOD_PKA_2 336 342 PF00069 0.412
MOD_PKA_2 354 360 PF00069 0.598
MOD_PKA_2 416 422 PF00069 0.634
MOD_PKA_2 515 521 PF00069 0.323
MOD_PKA_2 655 661 PF00069 0.406
MOD_PKA_2 675 681 PF00069 0.422
MOD_PKB_1 569 577 PF00069 0.290
MOD_PKB_1 88 96 PF00069 0.460
MOD_Plk_1 102 108 PF00069 0.444
MOD_Plk_1 296 302 PF00069 0.415
MOD_Plk_1 420 426 PF00069 0.446
MOD_Plk_1 463 469 PF00069 0.395
MOD_Plk_1 619 625 PF00069 0.426
MOD_Plk_4 102 108 PF00069 0.492
MOD_Plk_4 33 39 PF00069 0.350
MOD_Plk_4 366 372 PF00069 0.447
MOD_Plk_4 463 469 PF00069 0.395
MOD_Plk_4 526 532 PF00069 0.344
MOD_Plk_4 622 628 PF00069 0.531
MOD_ProDKin_1 106 112 PF00069 0.448
MOD_ProDKin_1 206 212 PF00069 0.459
MOD_ProDKin_1 267 273 PF00069 0.584
MOD_ProDKin_1 345 351 PF00069 0.640
MOD_ProDKin_1 362 368 PF00069 0.548
MOD_ProDKin_1 377 383 PF00069 0.568
MOD_ProDKin_1 629 635 PF00069 0.368
MOD_ProDKin_1 698 704 PF00069 0.421
TRG_DiLeu_BaLyEn_6 531 536 PF01217 0.427
TRG_DiLeu_BaLyEn_6 579 584 PF01217 0.266
TRG_ENDOCYTIC_2 211 214 PF00928 0.483
TRG_ENDOCYTIC_2 239 242 PF00928 0.609
TRG_ENDOCYTIC_2 450 453 PF00928 0.599
TRG_ENDOCYTIC_2 467 470 PF00928 0.289
TRG_ENDOCYTIC_2 636 639 PF00928 0.303
TRG_ER_diArg_1 15 18 PF00400 0.606
TRG_ER_diArg_1 331 333 PF00400 0.617
TRG_ER_diArg_1 416 418 PF00400 0.531
TRG_ER_diArg_1 485 488 PF00400 0.452
TRG_ER_diArg_1 55 57 PF00400 0.479
TRG_ER_diArg_1 568 571 PF00400 0.337
TRG_ER_diArg_1 87 90 PF00400 0.440
TRG_ER_diArg_1 9 12 PF00400 0.624
TRG_NLS_MonoExtC_3 484 489 PF00514 0.371
TRG_NLS_MonoExtC_3 654 659 PF00514 0.407
TRG_NLS_MonoExtN_4 655 660 PF00514 0.388
TRG_Pf-PMV_PEXEL_1 534 538 PF00026 0.472
TRG_Pf-PMV_PEXEL_1 571 576 PF00026 0.313
TRG_Pf-PMV_PEXEL_1 582 587 PF00026 0.315
TRG_Pf-PMV_PEXEL_1 81 85 PF00026 0.450

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IGN9 Leishmania donovani 40% 91%
A0A3S5H4Y6 Leishmania donovani 88% 91%
A0A3S5H4Y9 Leishmania donovani 35% 74%
A0A3S7WT86 Leishmania donovani 43% 72%
A0A3S7WWA6 Leishmania donovani 40% 91%
A0A451EJD9 Leishmania donovani 39% 90%
A0A451EJF4 Leishmania donovani 74% 90%
A0A451EJF6 Leishmania donovani 63% 100%
A0A451EJF8 Leishmania donovani 75% 95%
A0A451EJF9 Leishmania donovani 56% 85%
A4H3A9 Leishmania braziliensis 64% 100%
A4H3B4 Leishmania braziliensis 61% 100%
A4H3B5 Leishmania braziliensis 63% 100%
A4H3B6 Leishmania braziliensis 65% 100%
A4H3B8 Leishmania braziliensis 54% 100%
A4H3B9 Leishmania braziliensis 41% 100%
A4H4W8 Leishmania braziliensis 36% 100%
A4HJ20 Leishmania braziliensis 65% 100%
A4HNK3 Leishmania braziliensis 39% 99%
A4HNK6 Leishmania braziliensis 37% 100%
A4HRL9 Leishmania infantum 74% 100%
A4HRM1 Leishmania infantum 62% 100%
A4HRS1 Leishmania infantum 56% 85%
A4HRS3 Leishmania infantum 35% 74%
A4HRS5 Leishmania infantum 75% 95%
A4HZM0 Leishmania infantum 38% 100%
A4I7C7 Leishmania infantum 39% 90%
A4IAQ2 Leishmania infantum 38% 100%
E9AC91 Leishmania major 70% 100%
E9AC92 Leishmania major 69% 100%
E9AC95 Leishmania major 71% 100%
E9AC96 Leishmania major 57% 100%
E9AC98 Leishmania major 35% 100%
E9AEH8 Leishmania major 38% 100%
E9AHA6 Leishmania infantum 39% 90%
E9AIP8 Leishmania braziliensis 38% 100%
E9AJI3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 69% 100%
E9AJI4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 75% 100%
E9AJI5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 69% 100%
E9AJI6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 35% 100%
E9ALD6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 37% 100%
E9ASB8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 38% 100%
E9AXX8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 38% 100%
E9B2C0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 38% 100%
Q4Q5T6 Leishmania major 39% 100%
Q4QCL8 Leishmania major 39% 100%
Q4QFJ3 Leishmania major 44% 100%
Q4QIG9 Leishmania major 39% 100%
Q7YXU9 Leishmania major 39% 100%
Q7YXV1 Leishmania major 38% 100%
Q7YXV2 Leishmania major 40% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS