Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PLAC8 family - putative

Species:

Leishmania infantum

UniProt:

A4HRJ3_LEIIN

TriTrypDb:

LINF_010012100

Length:

521

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HRJ3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HRJ3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	102	106	PF00656	0.609
CLV_C14_Caspase3-7	118	122	PF00656	0.498
CLV_C14_Caspase3-7	21	25	PF00656	0.549
CLV_C14_Caspase3-7	245	249	PF00656	0.390
CLV_C14_Caspase3-7	59	63	PF00656	0.610
CLV_NRD_NRD_1	308	310	PF00675	0.331
CLV_NRD_NRD_1	311	313	PF00675	0.331
CLV_NRD_NRD_1	34	36	PF00675	0.570
CLV_PCSK_KEX2_1	308	310	PF00082	0.331
CLV_PCSK_KEX2_1	313	315	PF00082	0.331
CLV_PCSK_KEX2_1	34	36	PF00082	0.570
CLV_PCSK_PC1ET2_1	313	315	PF00082	0.390
CLV_PCSK_PC7_1	309	315	PF00082	0.390
CLV_PCSK_SKI1_1	131	135	PF00082	0.573
CLV_PCSK_SKI1_1	269	273	PF00082	0.382
CLV_PCSK_SKI1_1	35	39	PF00082	0.552
DEG_APCC_DBOX_1	50	58	PF00400	0.585
DEG_MDM2_SWIB_1	282	290	PF02201	0.445
DEG_SCF_FBW7_1	292	299	PF00400	0.477
DEG_SCF_FBW7_1	388	393	PF00400	0.469
DEG_SPOP_SBC_1	196	200	PF00917	0.640
DOC_CKS1_1	293	298	PF01111	0.477
DOC_CYCLIN_yClb3_PxF_3	172	178	PF00134	0.729
DOC_CYCLIN_yCln2_LP_2	211	217	PF00134	0.752
DOC_PP2B_PxIxI_1	502	508	PF00149	0.662
DOC_PP4_FxxP_1	178	181	PF00568	0.727
DOC_PP4_FxxP_1	441	444	PF00568	0.477
DOC_USP7_MATH_1	108	112	PF00917	0.625
DOC_USP7_MATH_1	191	195	PF00917	0.697
DOC_USP7_MATH_1	197	201	PF00917	0.746
DOC_USP7_MATH_1	246	250	PF00917	0.477
DOC_USP7_MATH_1	296	300	PF00917	0.477
DOC_USP7_MATH_1	361	365	PF00917	0.452
DOC_USP7_MATH_1	464	468	PF00917	0.617
DOC_USP7_MATH_1	68	72	PF00917	0.781
DOC_WW_Pin1_4	172	177	PF00397	0.645
DOC_WW_Pin1_4	292	297	PF00397	0.477
DOC_WW_Pin1_4	386	391	PF00397	0.390
DOC_WW_Pin1_4	411	416	PF00397	0.477
DOC_WW_Pin1_4	79	84	PF00397	0.690
LIG_14-3-3_CanoR_1	40	48	PF00244	0.615
LIG_BRCT_BRCA1_1	174	178	PF00533	0.729
LIG_BRCT_BRCA1_1	257	261	PF00533	0.390
LIG_Clathr_ClatBox_1	279	283	PF01394	0.331
LIG_deltaCOP1_diTrp_1	283	291	PF00928	0.477
LIG_deltaCOP1_diTrp_1	427	433	PF00928	0.399
LIG_FHA_1	274	280	PF00498	0.506
LIG_FHA_1	302	308	PF00498	0.350
LIG_FHA_1	349	355	PF00498	0.477
LIG_FHA_1	376	382	PF00498	0.399
LIG_FHA_1	387	393	PF00498	0.271
LIG_FHA_2	100	106	PF00498	0.712
LIG_FHA_2	348	354	PF00498	0.452
LIG_FHA_2	57	63	PF00498	0.609
LIG_Integrin_RGD_1	457	459	PF01839	0.660
LIG_Integrin_RGD_1	468	470	PF01839	0.537
LIG_Integrin_RGDW_4	457	460	PF00362	0.664
LIG_LIR_Apic_2	140	145	PF02991	0.708
LIG_LIR_Apic_2	175	181	PF02991	0.728
LIG_LIR_Apic_2	439	444	PF02991	0.477
LIG_LIR_Gen_1	125	134	PF02991	0.563
LIG_LIR_Gen_1	258	265	PF02991	0.390
LIG_LIR_Gen_1	321	331	PF02991	0.477
LIG_LIR_Gen_1	426	437	PF02991	0.390
LIG_LIR_Nem_3	125	129	PF02991	0.571
LIG_LIR_Nem_3	258	264	PF02991	0.390
LIG_LIR_Nem_3	426	432	PF02991	0.390
LIG_Pex14_1	429	433	PF04695	0.399
LIG_Pex14_2	282	286	PF04695	0.445
LIG_PTB_Apo_2	317	324	PF02174	0.477
LIG_SH2_CRK	126	130	PF00017	0.569
LIG_SH2_CRK	142	146	PF00017	0.511
LIG_SH2_CRK	187	191	PF00017	0.654
LIG_SH2_CRK	315	319	PF00017	0.477
LIG_SH2_CRK	420	424	PF00017	0.399
LIG_SH2_NCK_1	142	146	PF00017	0.637
LIG_SH2_PTP2	3	6	PF00017	0.559
LIG_SH2_SRC	185	188	PF00017	0.730
LIG_SH2_SRC	189	192	PF00017	0.604
LIG_SH2_SRC	3	6	PF00017	0.559
LIG_SH2_SRC	478	481	PF00017	0.683
LIG_SH2_STAP1	163	167	PF00017	0.558
LIG_SH2_STAT3	153	156	PF00017	0.574
LIG_SH2_STAT3	213	216	PF00017	0.731
LIG_SH2_STAT3	265	268	PF00017	0.477
LIG_SH2_STAT5	163	166	PF00017	0.612
LIG_SH2_STAT5	189	192	PF00017	0.713
LIG_SH2_STAT5	195	198	PF00017	0.626
LIG_SH2_STAT5	254	257	PF00017	0.331
LIG_SH2_STAT5	263	266	PF00017	0.331
LIG_SH2_STAT5	3	6	PF00017	0.559
LIG_SH2_STAT5	478	481	PF00017	0.683
LIG_SH3_3	126	132	PF00018	0.544
LIG_SH3_3	143	149	PF00018	0.570
LIG_SH3_3	170	176	PF00018	0.644
LIG_SH3_3	211	217	PF00018	0.748
LIG_SH3_3	290	296	PF00018	0.477
LIG_SH3_3	385	391	PF00018	0.477
LIG_SH3_3	412	418	PF00018	0.390
LIG_SH3_3	493	499	PF00018	0.740
LIG_TRFH_1	213	217	PF08558	0.757
LIG_WRC_WIRS_1	302	307	PF05994	0.366
MOD_CK1_1	104	110	PF00069	0.589
MOD_CK1_1	137	143	PF00069	0.560
MOD_CK1_1	298	304	PF00069	0.477
MOD_CK1_1	364	370	PF00069	0.477
MOD_CK1_1	41	47	PF00069	0.570
MOD_CK1_1	53	59	PF00069	0.504
MOD_CK1_1	71	77	PF00069	0.618
MOD_CK1_1	79	85	PF00069	0.588
MOD_CK2_1	347	353	PF00069	0.477
MOD_GlcNHglycan	105	109	PF01048	0.587
MOD_GlcNHglycan	165	168	PF01048	0.711
MOD_GlcNHglycan	181	184	PF01048	0.553
MOD_GlcNHglycan	203	206	PF01048	0.636
MOD_GlcNHglycan	244	247	PF01048	0.407
MOD_GlcNHglycan	35	38	PF01048	0.546
MOD_GlcNHglycan	43	46	PF01048	0.522
MOD_GlcNHglycan	73	76	PF01048	0.620
MOD_GlcNHglycan	78	81	PF01048	0.590
MOD_GlcNHglycan	85	88	PF01048	0.586
MOD_GSK3_1	103	110	PF00069	0.530
MOD_GSK3_1	191	198	PF00069	0.659
MOD_GSK3_1	238	245	PF00069	0.407
MOD_GSK3_1	292	299	PF00069	0.433
MOD_GSK3_1	330	337	PF00069	0.439
MOD_GSK3_1	386	393	PF00069	0.390
MOD_GSK3_1	46	53	PF00069	0.641
MOD_GSK3_1	58	65	PF00069	0.531
MOD_GSK3_1	79	86	PF00069	0.691
MOD_GSK3_1	95	102	PF00069	0.592
MOD_LATS_1	450	456	PF00433	0.390
MOD_N-GLC_1	122	127	PF02516	0.566
MOD_N-GLC_1	134	139	PF02516	0.484
MOD_N-GLC_1	41	46	PF02516	0.569
MOD_N-GLC_1	99	104	PF02516	0.590
MOD_NEK2_1	115	120	PF00069	0.558
MOD_NEK2_1	134	139	PF00069	0.443
MOD_NEK2_1	231	236	PF00069	0.506
MOD_NEK2_1	33	38	PF00069	0.538
MOD_NEK2_1	490	495	PF00069	0.688
MOD_NEK2_2	108	113	PF00069	0.602
MOD_PIKK_1	134	140	PF00454	0.552
MOD_PIKK_1	353	359	PF00454	0.417
MOD_PK_1	452	458	PF00069	0.636
MOD_PKA_2	33	39	PF00069	0.627
MOD_PKA_2	50	56	PF00069	0.490
MOD_Plk_1	364	370	PF00069	0.399
MOD_Plk_1	383	389	PF00069	0.178
MOD_Plk_1	452	458	PF00069	0.560
MOD_Plk_4	122	128	PF00069	0.566
MOD_Plk_4	191	197	PF00069	0.683
MOD_Plk_4	226	232	PF00069	0.704
MOD_Plk_4	246	252	PF00069	0.166
MOD_Plk_4	301	307	PF00069	0.390
MOD_Plk_4	428	434	PF00069	0.428
MOD_Plk_4	490	496	PF00069	0.685
MOD_Plk_4	53	59	PF00069	0.585
MOD_ProDKin_1	172	178	PF00069	0.646
MOD_ProDKin_1	292	298	PF00069	0.477
MOD_ProDKin_1	386	392	PF00069	0.390
MOD_ProDKin_1	411	417	PF00069	0.477
MOD_ProDKin_1	79	85	PF00069	0.690
TRG_DiLeu_BaEn_1	226	231	PF01217	0.705
TRG_ENDOCYTIC_2	126	129	PF00928	0.571
TRG_ENDOCYTIC_2	187	190	PF00928	0.660
TRG_ENDOCYTIC_2	315	318	PF00928	0.477
TRG_ENDOCYTIC_2	420	423	PF00928	0.399
TRG_ER_diArg_1	307	309	PF00400	0.329
TRG_ER_diArg_1	311	314	PF00400	0.339
TRG_ER_diArg_1	33	35	PF00400	0.557
TRG_NLS_MonoExtN_4	309	316	PF00514	0.390

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I3A7	Leptomonas seymouri	32%	94%
A0A3S5H4W6	Leishmania donovani	100%	100%