PLAC8 family protein

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PLAC8 family - putative

Species:

Leishmania infantum

UniProt:

A4HRJ2_LEIIN

TriTrypDb:

LINF_010012000

Length:

233

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Phosphorylation

Amastigote: 4

Expansion

Sequence features

A4HRJ2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HRJ2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
DOC_CYCLIN_yCln2_LP_2	224	230	PF00134	0.515
DOC_PP2B_LxvP_1	224	227	PF13499	0.468
DOC_PP4_FxxP_1	194	197	PF00568	0.410
DOC_USP7_MATH_1	131	135	PF00917	0.480
DOC_USP7_MATH_1	150	154	PF00917	0.331
DOC_USP7_MATH_1	163	167	PF00917	0.342
DOC_WW_Pin1_4	67	72	PF00397	0.644
LIG_14-3-3_CanoR_1	15	19	PF00244	0.674
LIG_14-3-3_CanoR_1	221	225	PF00244	0.510
LIG_BIR_II_1	1	5	PF00653	0.744
LIG_BRCT_BRCA1_1	138	142	PF00533	0.503
LIG_Clathr_ClatBox_1	122	126	PF01394	0.343
LIG_deltaCOP1_diTrp_1	212	218	PF00928	0.581
LIG_FHA_1	109	115	PF00498	0.389
LIG_FHA_1	181	187	PF00498	0.393
LIG_FHA_1	74	80	PF00498	0.410
LIG_LIR_Apic_2	191	197	PF02991	0.375
LIG_LIR_Nem_3	112	118	PF02991	0.410
LIG_LIR_Nem_3	139	145	PF02991	0.382
LIG_LIR_Nem_3	191	196	PF02991	0.278
LIG_Pex14_2	142	146	PF04695	0.439
LIG_Rb_LxCxE_1	76	91	PF01857	0.410
LIG_SH2_SRC	115	118	PF00017	0.410
LIG_SH2_SRC	135	138	PF00017	0.410
LIG_SH2_STAP1	222	226	PF00017	0.437
LIG_SH2_STAT3	222	225	PF00017	0.563
LIG_SH2_STAT5	115	118	PF00017	0.343
LIG_SH2_STAT5	135	138	PF00017	0.476
LIG_SH2_STAT5	145	148	PF00017	0.354
LIG_SH2_STAT5	97	100	PF00017	0.343
LIG_SH3_3	61	67	PF00018	0.630
LIG_SUMO_SIM_anti_2	182	191	PF11976	0.428
LIG_SUMO_SIM_par_1	182	191	PF11976	0.406
MOD_CDK_SPK_2	67	72	PF00069	0.596
MOD_CK1_1	130	136	PF00069	0.480
MOD_CK1_1	171	177	PF00069	0.441
MOD_CK1_1	182	188	PF00069	0.374
MOD_CK2_1	26	32	PF00069	0.724
MOD_GlcNHglycan	100	103	PF01048	0.515
MOD_GlcNHglycan	129	132	PF01048	0.484
MOD_GlcNHglycan	148	151	PF01048	0.489
MOD_GlcNHglycan	158	161	PF01048	0.358
MOD_GlcNHglycan	176	179	PF01048	0.240
MOD_GlcNHglycan	55	59	PF01048	0.682
MOD_GlcNHglycan	76	79	PF01048	0.352
MOD_GSK3_1	127	134	PF00069	0.348
MOD_GSK3_1	146	153	PF00069	0.357
MOD_GSK3_1	165	172	PF00069	0.369
MOD_GSK3_1	216	223	PF00069	0.645
MOD_LATS_1	52	58	PF00433	0.562
MOD_N-GLC_1	108	113	PF02516	0.352
MOD_NEK2_1	14	19	PF00069	0.679
MOD_NEK2_1	146	151	PF00069	0.486
MOD_NEK2_1	96	101	PF00069	0.405
MOD_PKA_2	14	20	PF00069	0.676
MOD_PKA_2	220	226	PF00069	0.633
MOD_PKA_2	53	59	PF00069	0.600
MOD_Plk_2-3	26	32	PF00069	0.654
MOD_Plk_4	131	137	PF00069	0.445
MOD_Plk_4	14	20	PF00069	0.676
MOD_Plk_4	141	147	PF00069	0.292
MOD_Plk_4	182	188	PF00069	0.440
MOD_ProDKin_1	67	73	PF00069	0.633
TRG_ENDOCYTIC_2	115	118	PF00928	0.413
TRG_ER_diArg_1	151	154	PF00400	0.369

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I201	Leptomonas seymouri	39%	100%
A0A451EJC3	Leishmania donovani	98%	100%
A4H387	Leishmania braziliensis	66%	98%
E9AC60	Leishmania major	88%	99%
E9AJF6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	98%