Putative fatty acyl CoA synthetase 2

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

fatty acyl CoA synthetase 2 - putative

Species:

Leishmania infantum

UniProt:

A4HRH4_LEIIN

TriTrypDb:

LINF_010010200

Length:

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HRH4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HRH4

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	3
GO:0004467	long-chain fatty acid-CoA ligase activity	3	3
GO:0015645	fatty acid ligase activity	2	3
GO:0016405	CoA-ligase activity	4	3
GO:0016874	ligase activity	2	3
GO:0016877	ligase activity, forming carbon-sulfur bonds	3	3
GO:0016878	acid-thiol ligase activity	4	3
GO:0140657	ATP-dependent activity	1	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	64	66	PF00675	0.660
CLV_NRD_NRD_1	71	73	PF00675	0.482
CLV_PCSK_KEX2_1	64	66	PF00082	0.689
CLV_PCSK_KEX2_1	70	72	PF00082	0.505
CLV_PCSK_SKI1_1	65	69	PF00082	0.562
DEG_Nend_UBRbox_2	1	3	PF02207	0.683
DOC_PP2B_LxvP_1	13	16	PF13499	0.457
DOC_USP7_MATH_1	9	13	PF00917	0.628
LIG_14-3-3_CanoR_1	70	77	PF00244	0.682
LIG_deltaCOP1_diTrp_1	53	60	PF00928	0.670
LIG_LIR_Gen_1	5	16	PF02991	0.527
LIG_LIR_Nem_3	5	11	PF02991	0.541
LIG_PCNA_PIPBox_1	1	10	PF02747	0.651
LIG_SH2_CRK	8	12	PF00017	0.630
LIG_SH2_NCK_1	8	12	PF00017	0.630
LIG_SH2_STAT5	29	32	PF00017	0.456
MOD_Cter_Amidation	68	71	PF01082	0.593
MOD_PKA_1	70	76	PF00069	0.726
MOD_PKA_2	70	76	PF00069	0.726
MOD_Plk_4	3	9	PF00069	0.637
TRG_ENDOCYTIC_2	8	11	PF00928	0.552
TRG_ER_diArg_1	64	66	PF00400	0.689
TRG_ER_diArg_1	70	72	PF00400	0.505

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WNK0	Leishmania donovani	100%	100%