Putative DNA excision/repair protein SNF2

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA excision/repair protein SNF2 - putative

Species:

Leishmania infantum

UniProt:

A4HRE5_LEIIN

TriTrypDb:

LINF_010007300

Length:

776

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HRE5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	10
GO:0003824	catalytic activity	1	10
GO:0005488	binding	1	10
GO:0005524	ATP binding	5	10
GO:0008094	ATP-dependent activity, acting on DNA	2	10
GO:0016491	oxidoreductase activity	2	10
GO:0017076	purine nucleotide binding	4	10
GO:0030554	adenyl nucleotide binding	5	10
GO:0032553	ribonucleotide binding	3	10
GO:0032555	purine ribonucleotide binding	4	10
GO:0032559	adenyl ribonucleotide binding	5	10
GO:0035639	purine ribonucleoside triphosphate binding	4	10
GO:0036094	small molecule binding	2	10
GO:0043167	ion binding	2	10
GO:0043168	anion binding	3	10
GO:0051213	dioxygenase activity	3	10
GO:0097159	organic cyclic compound binding	2	10
GO:0097367	carbohydrate derivative binding	2	10
GO:0140097	catalytic activity, acting on DNA	3	10
GO:0140640	catalytic activity, acting on a nucleic acid	2	10
GO:0140657	ATP-dependent activity	1	10
GO:0140658	ATP-dependent chromatin remodeler activity	3	10
GO:1901265	nucleoside phosphate binding	3	10
GO:1901363	heterocyclic compound binding	2	10
GO:0015616	DNA translocase activity	3	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	377	381	PF00656	0.569
CLV_C14_Caspase3-7	554	558	PF00656	0.466
CLV_C14_Caspase3-7	564	568	PF00656	0.537
CLV_C14_Caspase3-7	614	618	PF00656	0.653
CLV_NRD_NRD_1	202	204	PF00675	0.279
CLV_NRD_NRD_1	343	345	PF00675	0.277
CLV_NRD_NRD_1	349	351	PF00675	0.261
CLV_NRD_NRD_1	359	361	PF00675	0.253
CLV_NRD_NRD_1	387	389	PF00675	0.369
CLV_NRD_NRD_1	448	450	PF00675	0.420
CLV_NRD_NRD_1	492	494	PF00675	0.623
CLV_NRD_NRD_1	547	549	PF00675	0.557
CLV_NRD_NRD_1	60	62	PF00675	0.316
CLV_NRD_NRD_1	629	631	PF00675	0.712
CLV_NRD_NRD_1	68	70	PF00675	0.302
CLV_PCSK_FUR_1	357	361	PF00082	0.260
CLV_PCSK_FUR_1	61	65	PF00082	0.317
CLV_PCSK_FUR_1	627	631	PF00082	0.651
CLV_PCSK_KEX2_1	202	204	PF00082	0.268
CLV_PCSK_KEX2_1	343	345	PF00082	0.326
CLV_PCSK_KEX2_1	359	361	PF00082	0.223
CLV_PCSK_KEX2_1	387	389	PF00082	0.369
CLV_PCSK_KEX2_1	448	450	PF00082	0.420
CLV_PCSK_KEX2_1	473	475	PF00082	0.500
CLV_PCSK_KEX2_1	492	494	PF00082	0.623
CLV_PCSK_KEX2_1	547	549	PF00082	0.557
CLV_PCSK_KEX2_1	627	629	PF00082	0.738
CLV_PCSK_KEX2_1	63	65	PF00082	0.269
CLV_PCSK_PC1ET2_1	473	475	PF00082	0.500
CLV_PCSK_PC1ET2_1	63	65	PF00082	0.269
CLV_PCSK_PC7_1	444	450	PF00082	0.348
CLV_PCSK_PC7_1	543	549	PF00082	0.529
CLV_PCSK_SKI1_1	118	122	PF00082	0.334
CLV_PCSK_SKI1_1	128	132	PF00082	0.346
CLV_PCSK_SKI1_1	359	363	PF00082	0.268
CLV_PCSK_SKI1_1	455	459	PF00082	0.365
CLV_PCSK_SKI1_1	505	509	PF00082	0.403
CLV_PCSK_SKI1_1	513	517	PF00082	0.445
DEG_APCC_DBOX_1	358	366	PF00400	0.486
DEG_APCC_DBOX_1	508	516	PF00400	0.410
DEG_APCC_DBOX_1	542	550	PF00400	0.464
DEG_APCC_DBOX_1	71	79	PF00400	0.569
DEG_COP1_1	724	732	PF00400	0.465
DEG_SPOP_SBC_1	212	216	PF00917	0.521
DEG_SPOP_SBC_1	694	698	PF00917	0.443
DOC_CKS1_1	494	499	PF01111	0.516
DOC_CYCLIN_RxL_1	348	358	PF00134	0.482
DOC_MAPK_DCC_7	70	80	PF00069	0.539
DOC_MAPK_gen_1	357	367	PF00069	0.470
DOC_MAPK_gen_1	448	454	PF00069	0.426
DOC_MAPK_gen_1	627	633	PF00069	0.603
DOC_MAPK_MEF2A_6	217	226	PF00069	0.467
DOC_MAPK_MEF2A_6	284	293	PF00069	0.478
DOC_MAPK_MEF2A_6	334	341	PF00069	0.338
DOC_MAPK_MEF2A_6	72	80	PF00069	0.508
DOC_PP1_RVXF_1	349	356	PF00149	0.468
DOC_PP2B_LxvP_1	27	30	PF13499	0.539
DOC_PP2B_LxvP_1	712	715	PF13499	0.590
DOC_USP7_MATH_1	184	188	PF00917	0.538
DOC_USP7_MATH_1	477	481	PF00917	0.484
DOC_USP7_MATH_1	684	688	PF00917	0.693
DOC_USP7_MATH_1	699	703	PF00917	0.655
DOC_USP7_MATH_1	746	750	PF00917	0.336
DOC_USP7_MATH_1	91	95	PF00917	0.534
DOC_WW_Pin1_4	131	136	PF00397	0.468
DOC_WW_Pin1_4	380	385	PF00397	0.570
DOC_WW_Pin1_4	493	498	PF00397	0.661
DOC_WW_Pin1_4	578	583	PF00397	0.746
DOC_WW_Pin1_4	593	598	PF00397	0.653
DOC_WW_Pin1_4	666	671	PF00397	0.667
DOC_WW_Pin1_4	680	685	PF00397	0.623
DOC_WW_Pin1_4	695	700	PF00397	0.612
DOC_WW_Pin1_4	728	733	PF00397	0.599
LIG_14-3-3_CanoR_1	225	233	PF00244	0.553
LIG_14-3-3_CanoR_1	343	353	PF00244	0.489
LIG_14-3-3_CanoR_1	373	379	PF00244	0.528
LIG_14-3-3_CanoR_1	455	462	PF00244	0.360
LIG_14-3-3_CanoR_1	524	532	PF00244	0.604
LIG_14-3-3_CanoR_1	693	699	PF00244	0.550
LIG_14-3-3_CterR_2	773	776	PF00244	0.438
LIG_BIR_III_4	498	502	PF00653	0.637
LIG_BIR_III_4	569	573	PF00653	0.589
LIG_BRCT_BRCA1_1	357	361	PF00533	0.509
LIG_BRCT_BRCA1_1	765	769	PF00533	0.515
LIG_deltaCOP1_diTrp_1	141	149	PF00928	0.468
LIG_FHA_1	22	28	PF00498	0.468
LIG_FHA_1	283	289	PF00498	0.517
LIG_FHA_1	4	10	PF00498	0.468
LIG_FHA_1	405	411	PF00498	0.484
LIG_FHA_1	48	54	PF00498	0.444
LIG_FHA_1	561	567	PF00498	0.579
LIG_FHA_1	637	643	PF00498	0.557
LIG_FHA_1	666	672	PF00498	0.617
LIG_FHA_1	695	701	PF00498	0.575
LIG_FHA_1	80	86	PF00498	0.487
LIG_FHA_2	137	143	PF00498	0.579
LIG_FHA_2	257	263	PF00498	0.569
LIG_FHA_2	375	381	PF00498	0.532
LIG_FHA_2	459	465	PF00498	0.353
LIG_FHA_2	719	725	PF00498	0.688
LIG_FHA_2	94	100	PF00498	0.569
LIG_IBAR_NPY_1	317	319	PF08397	0.546
LIG_IRF3_LxIS_1	423	429	PF10401	0.416
LIG_LIR_Gen_1	139	147	PF02991	0.471
LIG_LIR_Gen_1	160	170	PF02991	0.517
LIG_LIR_Gen_1	358	369	PF02991	0.476
LIG_LIR_Gen_1	99	108	PF02991	0.468
LIG_LIR_LC3C_4	24	29	PF02991	0.569
LIG_LIR_Nem_3	141	147	PF02991	0.468
LIG_LIR_Nem_3	160	165	PF02991	0.468
LIG_LIR_Nem_3	358	364	PF02991	0.509
LIG_LIR_Nem_3	502	507	PF02991	0.447
LIG_LIR_Nem_3	683	688	PF02991	0.498
LIG_LIR_Nem_3	81	86	PF02991	0.456
LIG_LIR_Nem_3	99	103	PF02991	0.468
LIG_MYND_1	686	690	PF01753	0.526
LIG_NRBOX	364	370	PF00104	0.494
LIG_PCNA_PIPBox_1	143	152	PF02747	0.539
LIG_PDZ_Class_1	771	776	PF00595	0.443
LIG_Pex14_1	37	41	PF04695	0.569
LIG_Pex14_2	140	144	PF04695	0.468
LIG_PTB_Apo_2	466	473	PF02174	0.396
LIG_RPA_C_Fungi	444	456	PF08784	0.433
LIG_SH2_CRK	319	323	PF00017	0.477
LIG_SH2_CRK	73	77	PF00017	0.361
LIG_SH2_CRK	83	87	PF00017	0.273
LIG_SH2_PTP2	100	103	PF00017	0.422
LIG_SH2_STAP1	17	21	PF00017	0.463
LIG_SH2_STAP1	234	238	PF00017	0.422
LIG_SH2_STAT3	17	20	PF00017	0.422
LIG_SH2_STAT3	467	470	PF00017	0.397
LIG_SH2_STAT5	100	103	PF00017	0.322
LIG_SH2_STAT5	506	509	PF00017	0.385
LIG_SH3_3	25	31	PF00018	0.422
LIG_SH3_3	491	497	PF00018	0.686
LIG_SH3_3	592	598	PF00018	0.768
LIG_SH3_3	726	732	PF00018	0.588
LIG_SUMO_SIM_anti_2	24	30	PF11976	0.325
LIG_SUMO_SIM_anti_2	421	427	PF11976	0.323
LIG_SUMO_SIM_anti_2	528	534	PF11976	0.637
LIG_SUMO_SIM_anti_2	668	675	PF11976	0.636
LIG_SUMO_SIM_anti_2	731	739	PF11976	0.422
LIG_SUMO_SIM_anti_2	94	99	PF11976	0.347
LIG_SUMO_SIM_par_1	285	292	PF11976	0.325
LIG_SUMO_SIM_par_1	32	38	PF11976	0.408
LIG_SUMO_SIM_par_1	421	427	PF11976	0.377
LIG_TRAF2_1	461	464	PF00917	0.355
LIG_TYR_ITIM	98	103	PF00017	0.422
LIG_UBA3_1	154	159	PF00899	0.385
LIG_WRC_WIRS_1	137	142	PF05994	0.407
LIG_WRC_WIRS_1	364	369	PF05994	0.463
MOD_CDC14_SPxK_1	585	588	PF00782	0.664
MOD_CDK_SPxK_1	582	588	PF00069	0.660
MOD_CDK_SPxxK_3	380	387	PF00069	0.463
MOD_CK1_1	119	125	PF00069	0.437
MOD_CK1_1	35	41	PF00069	0.327
MOD_CK1_1	600	606	PF00069	0.629
MOD_CK1_1	692	698	PF00069	0.549
MOD_CK1_1	731	737	PF00069	0.629
MOD_CK2_1	212	218	PF00069	0.463
MOD_CK2_1	242	248	PF00069	0.397
MOD_CK2_1	256	262	PF00069	0.275
MOD_CK2_1	380	386	PF00069	0.386
MOD_CK2_1	458	464	PF00069	0.352
MOD_CK2_1	522	528	PF00069	0.603
MOD_CK2_1	699	705	PF00069	0.433
MOD_Cter_Amidation	490	493	PF01082	0.631
MOD_DYRK1A_RPxSP_1	493	497	PF00069	0.538
MOD_DYRK1A_RPxSP_1	680	684	PF00069	0.467
MOD_GlcNHglycan	118	121	PF01048	0.347
MOD_GlcNHglycan	165	168	PF01048	0.463
MOD_GlcNHglycan	176	180	PF01048	0.282
MOD_GlcNHglycan	244	247	PF01048	0.426
MOD_GlcNHglycan	276	280	PF01048	0.392
MOD_GlcNHglycan	420	423	PF01048	0.319
MOD_GlcNHglycan	432	435	PF01048	0.276
MOD_GlcNHglycan	582	585	PF01048	0.663
MOD_GlcNHglycan	591	594	PF01048	0.660
MOD_GlcNHglycan	649	652	PF01048	0.556
MOD_GlcNHglycan	708	711	PF01048	0.559
MOD_GlcNHglycan	748	751	PF01048	0.536
MOD_GlcNHglycan	765	768	PF01048	0.341
MOD_GSK3_1	253	260	PF00069	0.384
MOD_GSK3_1	275	282	PF00069	0.457
MOD_GSK3_1	349	356	PF00069	0.378
MOD_GSK3_1	426	433	PF00069	0.340
MOD_GSK3_1	578	585	PF00069	0.633
MOD_GSK3_1	589	596	PF00069	0.633
MOD_GSK3_1	674	681	PF00069	0.637
MOD_GSK3_1	689	696	PF00069	0.402
MOD_GSK3_1	758	765	PF00069	0.536
MOD_GSK3_1	768	775	PF00069	0.467
MOD_N-GLC_2	113	115	PF02516	0.385
MOD_N-GLC_2	558	560	PF02516	0.439
MOD_NEK2_1	150	155	PF00069	0.361
MOD_NEK2_1	157	162	PF00069	0.327
MOD_NEK2_1	21	26	PF00069	0.322
MOD_NEK2_1	267	272	PF00069	0.347
MOD_NEK2_1	289	294	PF00069	0.325
MOD_NEK2_1	3	8	PF00069	0.322
MOD_NEK2_1	353	358	PF00069	0.322
MOD_NEK2_1	374	379	PF00069	0.463
MOD_NEK2_1	405	410	PF00069	0.347
MOD_NEK2_1	426	431	PF00069	0.432
MOD_NEK2_1	674	679	PF00069	0.683
MOD_NEK2_1	736	741	PF00069	0.408
MOD_NEK2_1	79	84	PF00069	0.324
MOD_NEK2_1	93	98	PF00069	0.329
MOD_NEK2_2	279	284	PF00069	0.249
MOD_NEK2_2	477	482	PF00069	0.582
MOD_NMyristoyl	1	7	PF02799	0.191
MOD_PIKK_1	292	298	PF00454	0.407
MOD_PIKK_1	374	380	PF00454	0.463
MOD_PIKK_1	405	411	PF00454	0.322
MOD_PIKK_1	597	603	PF00454	0.703
MOD_PIKK_1	674	680	PF00454	0.642
MOD_PIKK_1	699	705	PF00454	0.563
MOD_PK_1	591	597	PF00069	0.682
MOD_PKA_2	224	230	PF00069	0.422
MOD_PKA_2	349	355	PF00069	0.329
MOD_PKA_2	372	378	PF00069	0.465
MOD_PKA_2	523	529	PF00069	0.619
MOD_PKA_2	674	680	PF00069	0.524
MOD_PKA_2	692	698	PF00069	0.333
MOD_PKA_2	715	721	PF00069	0.629
MOD_PKA_2	758	764	PF00069	0.580
MOD_PKB_1	611	619	PF00069	0.646
MOD_Plk_1	267	273	PF00069	0.288
MOD_Plk_1	426	432	PF00069	0.249
MOD_Plk_1	586	592	PF00069	0.681
MOD_Plk_1	633	639	PF00069	0.567
MOD_Plk_1	91	97	PF00069	0.406
MOD_Plk_2-3	257	263	PF00069	0.249
MOD_Plk_4	150	156	PF00069	0.322
MOD_Plk_4	165	171	PF00069	0.322
MOD_Plk_4	22	28	PF00069	0.382
MOD_Plk_4	289	295	PF00069	0.355
MOD_Plk_4	29	35	PF00069	0.311
MOD_Plk_4	301	307	PF00069	0.386
MOD_Plk_4	349	355	PF00069	0.322
MOD_Plk_4	363	369	PF00069	0.322
MOD_Plk_4	684	690	PF00069	0.646
MOD_Plk_4	731	737	PF00069	0.465
MOD_Plk_4	93	99	PF00069	0.463
MOD_ProDKin_1	131	137	PF00069	0.322
MOD_ProDKin_1	380	386	PF00069	0.465
MOD_ProDKin_1	493	499	PF00069	0.653
MOD_ProDKin_1	578	584	PF00069	0.744
MOD_ProDKin_1	593	599	PF00069	0.649
MOD_ProDKin_1	666	672	PF00069	0.673
MOD_ProDKin_1	680	686	PF00069	0.628
MOD_ProDKin_1	695	701	PF00069	0.576
MOD_ProDKin_1	728	734	PF00069	0.597
TRG_DiLeu_BaEn_1	528	533	PF01217	0.586
TRG_DiLeu_BaLyEn_6	284	289	PF01217	0.422
TRG_ENDOCYTIC_2	100	103	PF00928	0.322
TRG_ENDOCYTIC_2	234	237	PF00928	0.347
TRG_ENDOCYTIC_2	504	507	PF00928	0.410
TRG_ENDOCYTIC_2	83	86	PF00928	0.322
TRG_ER_diArg_1	201	203	PF00400	0.322
TRG_ER_diArg_1	342	344	PF00400	0.273
TRG_ER_diArg_1	357	360	PF00400	0.259
TRG_ER_diArg_1	492	494	PF00400	0.623
TRG_ER_diArg_1	546	548	PF00400	0.562
TRG_ER_diArg_1	612	615	PF00400	0.671
TRG_ER_diArg_1	626	629	PF00400	0.724
TRG_NES_CRM1_1	632	645	PF08389	0.447
TRG_NES_CRM1_1	92	105	PF08389	0.374
TRG_NLS_MonoCore_2	60	65	PF00514	0.407
TRG_NLS_MonoExtN_4	60	66	PF00514	0.417
TRG_NLS_MonoExtN_4	67	73	PF00514	0.427
TRG_PTS1	773	776	PF00515	0.438

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYE0	Leptomonas seymouri	65%	79%
A0A0P0WGX7	Oryza sativa subsp. japonica	31%	79%
A0A0S4JIZ6	Bodo saltans	26%	67%
A0A1X0NX57	Trypanosomatidae	25%	68%
A0A1X0P3S9	Trypanosomatidae	49%	100%
A0A3R7JZW4	Trypanosoma rangeli	27%	70%
A0A3R7M571	Trypanosoma rangeli	25%	100%
A0A3R7MS90	Trypanosoma rangeli	49%	100%
A0A3R7MWL4	Trypanosoma rangeli	22%	82%
A0A3S7WY74	Leishmania donovani	26%	69%
A0A3S7WZF4	Leishmania donovani	28%	74%
A0A451EJ80	Leishmania donovani	100%	84%
A4H349	Leishmania braziliensis	79%	100%
A4HDD3	Leishmania braziliensis	26%	69%
A4HGB7	Leishmania braziliensis	23%	100%
A4I0R4	Leishmania infantum	26%	69%
A4I1Q3	Leishmania infantum	28%	74%
A6ZL17	Saccharomyces cerevisiae (strain YJM789)	24%	84%
B3LN76	Saccharomyces cerevisiae (strain RM11-1a)	24%	84%
B3MMA5	Drosophila ananassae	26%	98%
B3NAN8	Drosophila erecta	26%	99%
B4GS98	Drosophila persimilis	26%	99%
B4JCS7	Drosophila grimshawi	25%	99%
B4KHL5	Drosophila mojavensis	26%	99%
B4M9A8	Drosophila virilis	26%	99%
B4MX21	Drosophila willistoni	26%	99%
B4NXB8	Drosophila yakuba	26%	99%
B5VE38	Saccharomyces cerevisiae (strain AWRI1631)	24%	84%
C7GQI8	Saccharomyces cerevisiae (strain JAY291)	24%	84%
D0A743	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	75%
D0A772	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	73%
E9AC13	Leishmania major	90%	100%
E9AJB0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
E9AWR6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	69%
F1Q8K0	Danio rerio	25%	100%
F4I2H2	Arabidopsis thaliana	28%	90%
O12944	Gallus gallus	25%	100%
O76460	Drosophila melanogaster	26%	99%
P31244	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	22%	98%
P32863	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	86%
P34739	Drosophila melanogaster	22%	73%
P38086	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	81%
P40352	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	72%
P41410	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	91%
P70270	Mus musculus	24%	100%
Q29KH2	Drosophila pseudoobscura pseudoobscura	26%	99%
Q4QAQ7	Leishmania major	26%	69%
Q5FWR0	Xenopus tropicalis	26%	77%
Q5NC05	Mus musculus	25%	68%
Q60848	Mus musculus	26%	95%
Q8W103	Arabidopsis thaliana	31%	71%
Q92698	Homo sapiens	25%	100%
Q9NRZ9	Homo sapiens	27%	93%
Q9UR24	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	80%
Q9ZUL5	Arabidopsis thaliana	28%	100%
V5B5G3	Trypanosoma cruzi	50%	100%
V5BR43	Trypanosoma cruzi	25%	70%
V5BVU6	Trypanosoma cruzi	26%	90%