Cytochrome c oxidase subunit I

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cytochrome oxidase subunit IX, putative

Species:

Leishmania braziliensis

UniProt:

A4HQM3_LEIBR

TriTrypDb:

LbrM.35.7390 , LBRM2903_350087200

Length:

124

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9
GO:0005737	cytoplasm	2	1

Expansion

Sequence features

A4HQM3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HQM3

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	5
GO:0016491	oxidoreductase activity	2	5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	91	93	PF00675	0.619
CLV_PCSK_KEX2_1	10	12	PF00082	0.442
CLV_PCSK_PC1ET2_1	10	12	PF00082	0.481
DEG_Nend_Nbox_1	1	3	PF02207	0.635
DOC_MAPK_gen_1	10	17	PF00069	0.712
DOC_USP7_MATH_1	16	20	PF00917	0.692
LIG_FHA_1	10	16	PF00498	0.711
LIG_LIR_Apic_2	37	43	PF02991	0.627
LIG_LIR_Gen_1	54	65	PF02991	0.342
LIG_LIR_Gen_1	66	75	PF02991	0.474
LIG_LIR_Nem_3	54	60	PF02991	0.354
LIG_LIR_Nem_3	66	72	PF02991	0.470
LIG_Pex14_1	95	99	PF04695	0.412
LIG_SH2_CRK	40	44	PF00017	0.619
MOD_Cter_Amidation	8	11	PF01082	0.336
MOD_GlcNHglycan	115	118	PF01048	0.713
MOD_GlcNHglycan	73	78	PF01048	0.679
MOD_PIKK_1	86	92	PF00454	0.491
MOD_Plk_1	95	101	PF00069	0.476
MOD_Plk_4	78	84	PF00069	0.517
MOD_SUMO_rev_2	89	94	PF00179	0.413

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P812	Leptomonas seymouri	90%	100%
A0A0S4KK00	Bodo saltans	63%	93%
A0A1X0NL41	Trypanosomatidae	79%	100%
A0A3Q8IM95	Leishmania donovani	92%	100%
A0A422NW07	Trypanosoma rangeli	79%	100%
A4ICE1	Leishmania infantum	92%	100%
D0A3S7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	79%	100%
E9AUD8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4Q052	Leishmania major	91%	100%