LeishMANIAdb
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Myosin_tail_1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Myosin_tail_1 domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HQJ1_LEIBR
TriTrypDb:
LbrM.35.7040 , LBRM2903_350083500
Length:
163

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HQJ1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HQJ1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 120 122 PF00675 0.611
CLV_NRD_NRD_1 18 20 PF00675 0.659
CLV_NRD_NRD_1 56 58 PF00675 0.561
CLV_PCSK_KEX2_1 157 159 PF00082 0.714
CLV_PCSK_KEX2_1 56 58 PF00082 0.547
CLV_PCSK_PC1ET2_1 157 159 PF00082 0.500
CLV_PCSK_SKI1_1 158 162 PF00082 0.614
CLV_PCSK_SKI1_1 4 8 PF00082 0.690
DOC_PP1_RVXF_1 141 148 PF00149 0.649
DOC_USP7_UBL2_3 4 8 PF12436 0.495
DOC_WW_Pin1_4 8 13 PF00397 0.664
LIG_EVH1_2 2 6 PF00568 0.749
LIG_FHA_1 59 65 PF00498 0.543
LIG_FHA_1 82 88 PF00498 0.621
LIG_FHA_2 63 69 PF00498 0.628
LIG_IRF3_LxIS_1 33 40 PF10401 0.427
LIG_SH2_NCK_1 159 163 PF00017 0.476
LIG_SUMO_SIM_anti_2 109 114 PF11976 0.399
LIG_SUMO_SIM_par_1 34 42 PF11976 0.574
LIG_TRAF2_1 11 14 PF00917 0.642
MOD_CK2_1 62 68 PF00069 0.644
MOD_CK2_1 8 14 PF00069 0.656
MOD_GSK3_1 58 65 PF00069 0.645
MOD_GSK3_1 77 84 PF00069 0.547
MOD_NEK2_1 151 156 PF00069 0.657
MOD_NEK2_1 6 11 PF00069 0.460
MOD_PIKK_1 24 30 PF00454 0.684
MOD_PKA_2 66 72 PF00069 0.606
MOD_Plk_2-3 62 68 PF00069 0.684
MOD_ProDKin_1 8 14 PF00069 0.662
MOD_SUMO_for_1 131 134 PF00179 0.676
MOD_SUMO_rev_2 117 124 PF00179 0.596
MOD_SUMO_rev_2 125 133 PF00179 0.625
MOD_SUMO_rev_2 68 76 PF00179 0.665
TRG_DiLeu_BaEn_1 107 112 PF01217 0.403
TRG_ER_diArg_1 56 58 PF00400 0.610
TRG_Pf-PMV_PEXEL_1 56 60 PF00026 0.579
TRG_Pf-PMV_PEXEL_1 70 74 PF00026 0.582
TRG_Pf-PMV_PEXEL_1 93 98 PF00026 0.728

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IM37 Leptomonas seymouri 66% 99%
A0A1X0NL82 Trypanosomatidae 33% 100%
A0A3R7NY60 Trypanosoma rangeli 34% 100%
A0A3S7XCF7 Leishmania donovani 84% 100%
D0A3N9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
E9AI00 Leishmania infantum 84% 100%
E9AUA4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%
Q4Q087 Leishmania major 80% 100%
V5AXM4 Trypanosoma cruzi 28% 81%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS