Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HQG7_LEIBR

TriTrypDb:

LbrM.35.6800 , LBRM2903_350081000

Length:

440

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HQG7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HQG7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	154	156	PF00675	0.523
CLV_NRD_NRD_1	283	285	PF00675	0.668
CLV_NRD_NRD_1	374	376	PF00675	0.711
CLV_NRD_NRD_1	59	61	PF00675	0.526
CLV_NRD_NRD_1	75	77	PF00675	0.418
CLV_NRD_NRD_1	93	95	PF00675	0.384
CLV_PCSK_FUR_1	91	95	PF00082	0.394
CLV_PCSK_KEX2_1	154	156	PF00082	0.523
CLV_PCSK_KEX2_1	283	285	PF00082	0.661
CLV_PCSK_KEX2_1	373	375	PF00082	0.707
CLV_PCSK_KEX2_1	414	416	PF00082	0.540
CLV_PCSK_KEX2_1	74	76	PF00082	0.562
CLV_PCSK_KEX2_1	93	95	PF00082	0.384
CLV_PCSK_PC1ET2_1	414	416	PF00082	0.540
CLV_PCSK_PC1ET2_1	74	76	PF00082	0.562
CLV_PCSK_SKI1_1	154	158	PF00082	0.582
CLV_PCSK_SKI1_1	247	251	PF00082	0.559
CLV_PCSK_SKI1_1	98	102	PF00082	0.368
DEG_Nend_UBRbox_3	1	3	PF02207	0.518
DEG_SCF_FBW7_1	140	145	PF00400	0.555
DEG_SPOP_SBC_1	8	12	PF00917	0.506
DOC_CKS1_1	143	148	PF01111	0.691
DOC_MAPK_gen_1	221	229	PF00069	0.623
DOC_MAPK_MEF2A_6	221	229	PF00069	0.623
DOC_PP2B_LxvP_1	144	147	PF13499	0.553
DOC_PP2B_LxvP_1	225	228	PF13499	0.708
DOC_USP7_MATH_1	147	151	PF00917	0.582
DOC_USP7_MATH_1	187	191	PF00917	0.708
DOC_USP7_MATH_1	206	210	PF00917	0.670
DOC_USP7_MATH_1	211	215	PF00917	0.695
DOC_USP7_MATH_1	260	264	PF00917	0.727
DOC_USP7_MATH_1	332	336	PF00917	0.585
DOC_USP7_MATH_1	356	360	PF00917	0.625
DOC_USP7_MATH_1	361	365	PF00917	0.640
DOC_WW_Pin1_4	111	116	PF00397	0.468
DOC_WW_Pin1_4	131	136	PF00397	0.570
DOC_WW_Pin1_4	138	143	PF00397	0.660
DOC_WW_Pin1_4	174	179	PF00397	0.600
DOC_WW_Pin1_4	182	187	PF00397	0.549
DOC_WW_Pin1_4	261	266	PF00397	0.694
DOC_WW_Pin1_4	289	294	PF00397	0.540
DOC_WW_Pin1_4	346	351	PF00397	0.609
LIG_14-3-3_CanoR_1	120	128	PF00244	0.488
LIG_14-3-3_CanoR_1	283	293	PF00244	0.665
LIG_14-3-3_CanoR_1	373	382	PF00244	0.680
LIG_BIR_III_2	112	116	PF00653	0.436
LIG_BRCT_BRCA1_1	276	280	PF00533	0.528
LIG_FHA_1	139	145	PF00498	0.638
LIG_FHA_1	177	183	PF00498	0.555
LIG_FHA_1	224	230	PF00498	0.646
LIG_FHA_1	277	283	PF00498	0.666
LIG_FHA_2	262	268	PF00498	0.624
LIG_FHA_2	63	69	PF00498	0.541
LIG_LIR_Nem_3	89	95	PF02991	0.393
LIG_MYND_1	142	146	PF01753	0.552
LIG_SH2_CRK	92	96	PF00017	0.389
LIG_SH2_SRC	431	434	PF00017	0.545
LIG_SH2_STAT3	55	58	PF00017	0.506
LIG_SH2_STAT5	431	434	PF00017	0.632
LIG_SH3_3	232	238	PF00018	0.564
LIG_SH3_3	311	317	PF00018	0.705
LIG_SH3_3	352	358	PF00018	0.616
LIG_WRC_WIRS_1	272	277	PF05994	0.536
LIG_WRC_WIRS_1	410	415	PF05994	0.544
MOD_CDK_SPxK_1	265	271	PF00069	0.561
MOD_CDK_SPxxK_3	111	118	PF00069	0.441
MOD_CDK_SPxxK_3	131	138	PF00069	0.512
MOD_CDK_SPxxK_3	176	183	PF00069	0.557
MOD_CK1_1	160	166	PF00069	0.544
MOD_CK1_1	242	248	PF00069	0.666
MOD_CK1_1	274	280	PF00069	0.532
MOD_CK1_1	385	391	PF00069	0.717
MOD_CK1_1	405	411	PF00069	0.513
MOD_CK1_1	424	430	PF00069	0.631
MOD_CK1_1	9	15	PF00069	0.635
MOD_CK2_1	17	23	PF00069	0.442
MOD_CK2_1	206	212	PF00069	0.579
MOD_CK2_1	261	267	PF00069	0.629
MOD_CK2_1	291	297	PF00069	0.541
MOD_CK2_1	373	379	PF00069	0.709
MOD_CK2_1	388	394	PF00069	0.584
MOD_CK2_1	423	429	PF00069	0.540
MOD_CK2_1	62	68	PF00069	0.533
MOD_DYRK1A_RPxSP_1	138	142	PF00069	0.564
MOD_GlcNHglycan	12	15	PF01048	0.728
MOD_GlcNHglycan	162	165	PF01048	0.601
MOD_GlcNHglycan	193	196	PF01048	0.643
MOD_GlcNHglycan	250	253	PF01048	0.634
MOD_GlcNHglycan	257	261	PF01048	0.686
MOD_GlcNHglycan	340	344	PF01048	0.572
MOD_GlcNHglycan	375	378	PF01048	0.624
MOD_GlcNHglycan	384	387	PF01048	0.576
MOD_GlcNHglycan	404	407	PF01048	0.637
MOD_GlcNHglycan	426	429	PF01048	0.680
MOD_GSK3_1	134	141	PF00069	0.560
MOD_GSK3_1	158	165	PF00069	0.671
MOD_GSK3_1	182	189	PF00069	0.704
MOD_GSK3_1	216	223	PF00069	0.575
MOD_GSK3_1	239	246	PF00069	0.664
MOD_GSK3_1	256	263	PF00069	0.622
MOD_GSK3_1	298	305	PF00069	0.607
MOD_GSK3_1	345	352	PF00069	0.597
MOD_GSK3_1	381	388	PF00069	0.621
MOD_GSK3_1	405	412	PF00069	0.677
MOD_GSK3_1	423	430	PF00069	0.574
MOD_GSK3_1	50	57	PF00069	0.477
MOD_GSK3_1	6	13	PF00069	0.647
MOD_GSK3_1	62	69	PF00069	0.438
MOD_GSK3_1	98	105	PF00069	0.375
MOD_N-GLC_1	382	387	PF02516	0.568
MOD_NEK2_1	157	162	PF00069	0.533
MOD_NEK2_1	248	253	PF00069	0.700
MOD_NEK2_1	276	281	PF00069	0.669
MOD_NEK2_1	298	303	PF00069	0.674
MOD_NEK2_1	308	313	PF00069	0.617
MOD_NEK2_1	66	71	PF00069	0.494
MOD_NEK2_2	62	67	PF00069	0.385
MOD_PIKK_1	104	110	PF00454	0.512
MOD_PIKK_1	121	127	PF00454	0.467
MOD_PIKK_1	163	169	PF00454	0.554
MOD_PIKK_1	54	60	PF00454	0.512
MOD_PK_1	76	82	PF00069	0.434
MOD_PKA_1	283	289	PF00069	0.664
MOD_PKA_1	373	379	PF00069	0.709
MOD_PKA_1	414	420	PF00069	0.669
MOD_PKA_2	220	226	PF00069	0.627
MOD_PKA_2	283	289	PF00069	0.664
MOD_PKA_2	373	379	PF00069	0.709
MOD_PKA_2	414	420	PF00069	0.527
MOD_PKA_2	66	72	PF00069	0.470
MOD_PKB_1	96	104	PF00069	0.375
MOD_Plk_1	76	82	PF00069	0.640
MOD_Plk_4	17	23	PF00069	0.501
MOD_Plk_4	271	277	PF00069	0.571
MOD_Plk_4	291	297	PF00069	0.569
MOD_Plk_4	427	433	PF00069	0.687
MOD_Plk_4	76	82	PF00069	0.434
MOD_ProDKin_1	111	117	PF00069	0.472
MOD_ProDKin_1	131	137	PF00069	0.571
MOD_ProDKin_1	138	144	PF00069	0.661
MOD_ProDKin_1	174	180	PF00069	0.594
MOD_ProDKin_1	182	188	PF00069	0.551
MOD_ProDKin_1	261	267	PF00069	0.693
MOD_ProDKin_1	289	295	PF00069	0.541
MOD_ProDKin_1	346	352	PF00069	0.611
MOD_SUMO_rev_2	292	301	PF00179	0.538
TRG_DiLeu_BaLyEn_6	244	249	PF01217	0.555
TRG_ENDOCYTIC_2	92	95	PF00928	0.383
TRG_ER_diArg_1	153	155	PF00400	0.530
TRG_ER_diArg_1	282	284	PF00400	0.604
TRG_ER_diArg_1	373	375	PF00400	0.703
TRG_ER_diArg_1	92	94	PF00400	0.393
TRG_Pf-PMV_PEXEL_1	120	125	PF00026	0.620
TRG_Pf-PMV_PEXEL_1	155	159	PF00026	0.525
TRG_Pf-PMV_PEXEL_1	93	97	PF00026	0.383

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ILD3	Leishmania donovani	54%	94%
A4ICA3	Leishmania infantum	54%	94%
Q4Q0B1	Leishmania major	56%	100%