CID domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HQG4_LEIBR

TriTrypDb:

LbrM.35.6770 , LBRM2903_350080600

Length:

311

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HQG4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HQG4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	221	223	PF00675	0.519
CLV_NRD_NRD_1	8	10	PF00675	0.456
CLV_PCSK_KEX2_1	215	217	PF00082	0.610
CLV_PCSK_KEX2_1	79	81	PF00082	0.441
CLV_PCSK_KEX2_1	8	10	PF00082	0.456
CLV_PCSK_PC1ET2_1	215	217	PF00082	0.357
CLV_PCSK_PC1ET2_1	79	81	PF00082	0.441
CLV_PCSK_SKI1_1	175	179	PF00082	0.648
CLV_PCSK_SKI1_1	249	253	PF00082	0.546
DEG_APCC_DBOX_1	54	62	PF00400	0.361
DEG_APCC_DBOX_1	79	87	PF00400	0.442
DEG_Nend_UBRbox_3	1	3	PF02207	0.513
DEG_SPOP_SBC_1	250	254	PF00917	0.608
DOC_MAPK_gen_1	215	221	PF00069	0.594
DOC_PP2B_LxvP_1	88	91	PF13499	0.524
DOC_USP7_MATH_1	224	228	PF00917	0.556
DOC_USP7_MATH_1	250	254	PF00917	0.692
DOC_USP7_MATH_1	78	82	PF00917	0.515
DOC_USP7_UBL2_3	44	48	PF12436	0.529
LIG_14-3-3_CanoR_1	147	151	PF00244	0.721
LIG_14-3-3_CanoR_1	249	259	PF00244	0.755
LIG_14-3-3_CanoR_1	264	271	PF00244	0.535
LIG_14-3-3_CanoR_1	55	59	PF00244	0.412
LIG_14-3-3_CanoR_1	80	84	PF00244	0.372
LIG_14-3-3_CanoR_1	99	109	PF00244	0.599
LIG_CaM_NSCaTE_8	129	136	PF13499	0.313
LIG_deltaCOP1_diTrp_1	117	125	PF00928	0.557
LIG_EH1_1	59	67	PF00400	0.476
LIG_eIF4E_1	60	66	PF01652	0.435
LIG_FHA_1	104	110	PF00498	0.569
LIG_FHA_1	15	21	PF00498	0.567
LIG_FHA_1	48	54	PF00498	0.456
LIG_FHA_1	69	75	PF00498	0.616
LIG_FHA_2	134	140	PF00498	0.599
LIG_GBD_Chelix_1	58	66	PF00786	0.503
LIG_LIR_Gen_1	25	34	PF02991	0.469
LIG_LIR_Nem_3	116	122	PF02991	0.440
LIG_LIR_Nem_3	25	29	PF02991	0.472
LIG_LIR_Nem_3	305	310	PF02991	0.450
LIG_Pex14_2	125	129	PF04695	0.415
LIG_SH2_SRC	164	167	PF00017	0.594
LIG_SH2_SRC	60	63	PF00017	0.504
LIG_SH2_STAT5	40	43	PF00017	0.542
LIG_SH2_STAT5	60	63	PF00017	0.431
LIG_SH3_3	275	281	PF00018	0.675
LIG_TRAF2_1	136	139	PF00917	0.351
LIG_UBA3_1	109	114	PF00899	0.543
LIG_UBA3_1	218	223	PF00899	0.593
LIG_WRC_WIRS_1	303	308	PF05994	0.663
MOD_CK1_1	103	109	PF00069	0.567
MOD_CK1_1	145	151	PF00069	0.628
MOD_CK1_1	254	260	PF00069	0.696
MOD_CK1_1	305	311	PF00069	0.606
MOD_CK1_1	68	74	PF00069	0.600
MOD_CK2_1	133	139	PF00069	0.335
MOD_CK2_1	224	230	PF00069	0.592
MOD_GlcNHglycan	151	154	PF01048	0.576
MOD_GlcNHglycan	185	188	PF01048	0.714
MOD_GlcNHglycan	189	192	PF01048	0.726
MOD_GlcNHglycan	199	202	PF01048	0.694
MOD_GlcNHglycan	254	257	PF01048	0.710
MOD_GlcNHglycan	292	295	PF01048	0.727
MOD_GlcNHglycan	91	94	PF01048	0.552
MOD_GSK3_1	128	135	PF00069	0.450
MOD_GSK3_1	142	149	PF00069	0.620
MOD_GSK3_1	183	190	PF00069	0.721
MOD_GSK3_1	193	200	PF00069	0.720
MOD_GSK3_1	250	257	PF00069	0.665
MOD_GSK3_1	68	75	PF00069	0.614
MOD_N-GLC_1	182	187	PF02516	0.743
MOD_NEK2_1	133	138	PF00069	0.546
MOD_NEK2_1	65	70	PF00069	0.393
MOD_PKA_1	79	85	PF00069	0.443
MOD_PKA_2	100	106	PF00069	0.578
MOD_PKA_2	146	152	PF00069	0.680
MOD_PKA_2	263	269	PF00069	0.594
MOD_PKA_2	54	60	PF00069	0.475
MOD_PKA_2	79	85	PF00069	0.466
MOD_Plk_1	103	109	PF00069	0.567
MOD_Plk_4	302	308	PF00069	0.666
MOD_Plk_4	54	60	PF00069	0.470
MOD_SUMO_for_1	177	180	PF00179	0.613
MOD_SUMO_for_1	282	285	PF00179	0.800
MOD_SUMO_for_1	296	299	PF00179	0.531
TRG_ER_diArg_1	8	10	PF00400	0.456
TRG_ER_diArg_1	98	101	PF00400	0.570

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4IY70	Bodo saltans	29%	100%
A0A1X0NLM3	Trypanosomatidae	32%	100%
A0A3Q8IGT5	Leishmania donovani	85%	100%
A0A3R7NPS1	Trypanosoma rangeli	34%	100%
A4ICA0	Leishmania infantum	86%	100%
D0A3L5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9AU80	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4Q0B4	Leishmania major	85%	100%
V5D8U2	Trypanosoma cruzi	34%	100%