Putative ubiquitin-protein ligase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ubiquitin-protein ligase, putative

Species:

Leishmania braziliensis

UniProt:

A4HQF1_LEIBR

TriTrypDb:

LbrM.35.6640 , LBRM2903_350078100

Length:

4169

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 8

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HQF1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Could not find GO biological_process term for this entry.

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	9
GO:0004842	ubiquitin-protein transferase activity	4	9
GO:0016740	transferase activity	2	9
GO:0016874	ligase activity	2	8
GO:0019787	ubiquitin-like protein transferase activity	3	9
GO:0140096	catalytic activity, acting on a protein	2	9

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1381	1385	PF00656	0.344
CLV_C14_Caspase3-7	1435	1439	PF00656	0.501
CLV_C14_Caspase3-7	17	21	PF00656	0.534
CLV_C14_Caspase3-7	2180	2184	PF00656	0.531
CLV_C14_Caspase3-7	2366	2370	PF00656	0.609
CLV_C14_Caspase3-7	3902	3906	PF00656	0.331
CLV_C14_Caspase3-7	4089	4093	PF00656	0.444
CLV_C14_Caspase3-7	633	637	PF00656	0.413
CLV_C14_Caspase3-7	875	879	PF00656	0.372
CLV_NRD_NRD_1	1181	1183	PF00675	0.416

Previous1 2 3 4 5…134Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I483	Leptomonas seymouri	61%	99%
A0A3S7XC43	Leishmania donovani	85%	100%
A4IC88	Leishmania infantum	86%	100%
D0A3T5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9AU68	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4Q0C6	Leishmania major	85%	100%
V5BHC4	Trypanosoma cruzi	35%	100%

Previous1Next