Sucraseferredoxin family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Sucrase/ferredoxin-like, putative

Species:

Leishmania braziliensis

UniProt:

A4HQD8_LEIBR

TriTrypDb:

LbrM.35.6500 , LBRM2903_350076500

Length:

257

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	2
GO:0016020	membrane	2	1

Expansion

Sequence features

A4HQD8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HQD8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	228	232	PF00656	0.365
CLV_PCSK_FUR_1	86	90	PF00082	0.339
CLV_PCSK_KEX2_1	88	90	PF00082	0.504
CLV_PCSK_PC1ET2_1	88	90	PF00082	0.504
DEG_APCC_DBOX_1	17	25	PF00400	0.481
DOC_USP7_MATH_1	90	94	PF00917	0.475
LIG_14-3-3_CanoR_1	18	22	PF00244	0.566
LIG_14-3-3_CanoR_1	189	193	PF00244	0.433
LIG_14-3-3_CanoR_1	89	95	PF00244	0.320
LIG_eIF4E_1	165	171	PF01652	0.336
LIG_FHA_1	114	120	PF00498	0.420
LIG_FHA_1	138	144	PF00498	0.472
LIG_FHA_1	43	49	PF00498	0.505
LIG_FHA_1	70	76	PF00498	0.453
LIG_FHA_2	18	24	PF00498	0.479
LIG_FHA_2	226	232	PF00498	0.290
LIG_LIR_Apic_2	128	134	PF02991	0.450
LIG_LIR_Gen_1	148	157	PF02991	0.419
LIG_LIR_Gen_1	8	16	PF02991	0.573
LIG_LIR_Nem_3	122	127	PF02991	0.358
LIG_LIR_Nem_3	146	152	PF02991	0.343
LIG_LIR_Nem_3	8	12	PF02991	0.574
LIG_SH2_CRK	124	128	PF00017	0.357
LIG_SH2_STAT5	149	152	PF00017	0.412
LIG_SH2_STAT5	165	168	PF00017	0.209
LIG_SUMO_SIM_par_1	139	144	PF11976	0.472
LIG_TYR_ITSM	120	127	PF00017	0.370
MOD_CK1_1	125	131	PF00069	0.368
MOD_CK2_1	182	188	PF00069	0.219
MOD_CK2_1	49	55	PF00069	0.533
MOD_GlcNHglycan	124	127	PF01048	0.360
MOD_GlcNHglycan	144	148	PF01048	0.368
MOD_GlcNHglycan	184	187	PF01048	0.369
MOD_GSK3_1	178	185	PF00069	0.377
MOD_GSK3_1	90	97	PF00069	0.500
MOD_LATS_1	109	115	PF00433	0.307
MOD_NEK2_1	152	157	PF00069	0.366
MOD_NEK2_1	182	187	PF00069	0.304
MOD_NEK2_1	58	63	PF00069	0.434
MOD_NEK2_1	94	99	PF00069	0.452
MOD_NEK2_2	49	54	PF00069	0.564
MOD_PIKK_1	113	119	PF00454	0.360
MOD_PIKK_1	79	85	PF00454	0.403
MOD_PKA_2	17	23	PF00069	0.439
MOD_PKA_2	178	184	PF00069	0.357
MOD_PKA_2	188	194	PF00069	0.413
MOD_Plk_1	103	109	PF00069	0.432
MOD_Plk_2-3	225	231	PF00069	0.306
MOD_Plk_2-3	5	11	PF00069	0.581
MOD_Plk_4	103	109	PF00069	0.447
MOD_Plk_4	165	171	PF00069	0.411
MOD_Plk_4	225	231	PF00069	0.306
MOD_SUMO_for_1	221	224	PF00179	0.450
MOD_SUMO_rev_2	132	140	PF00179	0.381
TRG_DiLeu_BaEn_2	147	153	PF01217	0.352
TRG_ENDOCYTIC_2	124	127	PF00928	0.340
TRG_ENDOCYTIC_2	149	152	PF00928	0.450
TRG_ENDOCYTIC_2	218	221	PF00928	0.450

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8U1	Leptomonas seymouri	40%	97%
A0A0N1I8X6	Leptomonas seymouri	71%	100%
A0A0S4JXX0	Bodo saltans	43%	98%
A0A1X0NM84	Trypanosomatidae	49%	99%
A0A3Q8IGR7	Leishmania donovani	81%	95%
A0A422NAD6	Trypanosoma rangeli	48%	100%
A4IE29	Leishmania infantum	81%	95%
D0A3V9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	90%
E9AU53	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4Q0E2	Leishmania major	81%	100%
V5DJZ4	Trypanosoma cruzi	50%	78%