RanBD1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HQD5_LEIBR

TriTrypDb:

LbrM.35.6470 , LBRM2903_350076300

Length:

328

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HQD5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HQD5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	191	195	PF00656	0.527
CLV_NRD_NRD_1	167	169	PF00675	0.589
CLV_PCSK_SKI1_1	208	212	PF00082	0.449
CLV_PCSK_SKI1_1	217	221	PF00082	0.460
CLV_PCSK_SKI1_1	271	275	PF00082	0.545
CLV_PCSK_SKI1_1	5	9	PF00082	0.479
DEG_Nend_UBRbox_2	1	3	PF02207	0.491
DEG_SPOP_SBC_1	120	124	PF00917	0.537
DEG_SPOP_SBC_1	44	48	PF00917	0.541
DOC_CYCLIN_RxL_1	268	277	PF00134	0.463
DOC_MAPK_FxFP_2	41	44	PF00069	0.524
DOC_MAPK_gen_1	3	12	PF00069	0.478
DOC_PP4_FxxP_1	27	30	PF00568	0.639
DOC_PP4_FxxP_1	301	304	PF00568	0.426
DOC_PP4_FxxP_1	41	44	PF00568	0.487
DOC_PP4_FxxP_1	8	11	PF00568	0.593
DOC_USP7_MATH_1	119	123	PF00917	0.659
DOC_USP7_MATH_1	160	164	PF00917	0.596
DOC_USP7_MATH_1	30	34	PF00917	0.774
DOC_USP7_MATH_1	37	41	PF00917	0.679
DOC_USP7_MATH_1	81	85	PF00917	0.553
DOC_USP7_UBL2_3	5	9	PF12436	0.479
DOC_WW_Pin1_4	225	230	PF00397	0.656
DOC_WW_Pin1_4	35	40	PF00397	0.510
DOC_WW_Pin1_4	45	50	PF00397	0.510
LIG_BRCT_BRCA1_1	113	117	PF00533	0.604
LIG_BRCT_BRCA1_1	153	157	PF00533	0.585
LIG_BRCT_BRCA1_1	215	219	PF00533	0.307
LIG_BRCT_BRCA1_1	23	27	PF00533	0.485
LIG_BRCT_BRCA1_1	37	41	PF00533	0.618
LIG_BRCT_BRCA1_1	92	96	PF00533	0.571
LIG_Clathr_ClatBox_1	218	222	PF01394	0.313
LIG_FHA_1	294	300	PF00498	0.516
LIG_FHA_2	124	130	PF00498	0.667
LIG_FHA_2	46	52	PF00498	0.524
LIG_FHA_2	57	63	PF00498	0.499
LIG_LIR_Apic_2	24	30	PF02991	0.619
LIG_LIR_Apic_2	38	44	PF02991	0.497
LIG_PDZ_Class_3	323	328	PF00595	0.389
LIG_Pex14_2	113	117	PF04695	0.609
LIG_Pex14_2	8	12	PF04695	0.483
LIG_SH2_STAP1	263	267	PF00017	0.392
LIG_SH2_STAT5	297	300	PF00017	0.392
LIG_SH3_3	130	136	PF00018	0.575
LIG_SH3_3	142	148	PF00018	0.593
LIG_SH3_3	67	73	PF00018	0.640
LIG_SH3_4	5	12	PF00018	0.480
LIG_SUMO_SIM_par_1	284	292	PF11976	0.399
LIG_TRAF2_1	127	130	PF00917	0.551
LIG_UBA3_1	273	278	PF00899	0.462
LIG_WRC_WIRS_1	161	166	PF05994	0.520
LIG_WRC_WIRS_1	22	27	PF05994	0.487
MOD_CDK_SPxK_1	225	231	PF00069	0.529
MOD_CK1_1	111	117	PF00069	0.657
MOD_CK1_1	122	128	PF00069	0.754
MOD_CK1_1	18	24	PF00069	0.580
MOD_CK1_1	32	38	PF00069	0.629
MOD_CK1_1	50	56	PF00069	0.616
MOD_CK1_1	85	91	PF00069	0.614
MOD_CK1_1	92	98	PF00069	0.655
MOD_CK2_1	123	129	PF00069	0.565
MOD_CK2_1	160	166	PF00069	0.647
MOD_CK2_1	203	209	PF00069	0.444
MOD_CK2_1	274	280	PF00069	0.396
MOD_CK2_1	45	51	PF00069	0.527
MOD_CK2_1	56	62	PF00069	0.504
MOD_GlcNHglycan	103	106	PF01048	0.783
MOD_GlcNHglycan	158	161	PF01048	0.498
MOD_GlcNHglycan	204	208	PF01048	0.591
MOD_GlcNHglycan	236	239	PF01048	0.355
MOD_GlcNHglycan	31	35	PF01048	0.537
MOD_GlcNHglycan	84	87	PF01048	0.648
MOD_GSK3_1	119	126	PF00069	0.606
MOD_GSK3_1	156	163	PF00069	0.526
MOD_GSK3_1	17	24	PF00069	0.591
MOD_GSK3_1	193	200	PF00069	0.733
MOD_GSK3_1	307	314	PF00069	0.398
MOD_GSK3_1	43	50	PF00069	0.612
MOD_GSK3_1	61	68	PF00069	0.762
MOD_GSK3_1	72	79	PF00069	0.662
MOD_GSK3_1	81	88	PF00069	0.613
MOD_GSK3_1	92	99	PF00069	0.632
MOD_N-GLC_1	265	270	PF02516	0.372
MOD_N-GLC_1	308	313	PF02516	0.398
MOD_N-GLC_1	81	86	PF02516	0.542
MOD_NEK2_1	265	270	PF00069	0.416
MOD_NEK2_1	274	279	PF00069	0.437
MOD_NEK2_1	299	304	PF00069	0.419
MOD_NEK2_1	54	59	PF00069	0.682
MOD_NEK2_1	76	81	PF00069	0.519
MOD_NEK2_1	90	95	PF00069	0.482
MOD_NEK2_1	96	101	PF00069	0.519
MOD_PIKK_1	32	38	PF00454	0.691
MOD_PIKK_1	76	82	PF00454	0.535
MOD_Plk_1	111	117	PF00069	0.506
MOD_Plk_1	265	271	PF00069	0.381
MOD_Plk_1	50	56	PF00069	0.538
MOD_Plk_4	160	166	PF00069	0.517
MOD_Plk_4	293	299	PF00069	0.394
MOD_ProDKin_1	225	231	PF00069	0.655
MOD_ProDKin_1	35	41	PF00069	0.514
MOD_ProDKin_1	45	51	PF00069	0.513
MOD_SUMO_rev_2	234	243	PF00179	0.500
TRG_DiLeu_BaEn_1	280	285	PF01217	0.377
TRG_DiLeu_BaLyEn_6	253	258	PF01217	0.407
TRG_NLS_MonoExtC_3	167	173	PF00514	0.600

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFC6	Leptomonas seymouri	53%	78%
A0A3Q8IWI8	Leishmania donovani	70%	100%
A4IE27	Leishmania infantum	70%	100%
E9AU51	Leishmania mexicana (strain MHOM/GT/2001/U1103)	69%	100%
Q4Q0E4	Leishmania major	71%	100%