L6202.3-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

l6202.3-like protein

Species:

Leishmania braziliensis

UniProt:

A4HQB9_LEIBR

TriTrypDb:

LbrM.35.6310 , LBRM2903_350074500

Length:

824

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HQB9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HQB9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	307	311	PF00656	0.498
CLV_MEL_PAP_1	521	527	PF00089	0.485
CLV_NRD_NRD_1	138	140	PF00675	0.375
CLV_NRD_NRD_1	144	146	PF00675	0.381
CLV_NRD_NRD_1	15	17	PF00675	0.466
CLV_NRD_NRD_1	226	228	PF00675	0.521
CLV_NRD_NRD_1	239	241	PF00675	0.385
CLV_NRD_NRD_1	26	28	PF00675	0.398
CLV_NRD_NRD_1	296	298	PF00675	0.449
CLV_NRD_NRD_1	450	452	PF00675	0.394
CLV_NRD_NRD_1	470	472	PF00675	0.568
CLV_NRD_NRD_1	523	525	PF00675	0.479
CLV_NRD_NRD_1	611	613	PF00675	0.530
CLV_NRD_NRD_1	644	646	PF00675	0.586
CLV_PCSK_FUR_1	224	228	PF00082	0.521
CLV_PCSK_KEX2_1	102	104	PF00082	0.382
CLV_PCSK_KEX2_1	138	140	PF00082	0.375
CLV_PCSK_KEX2_1	144	146	PF00082	0.381
CLV_PCSK_KEX2_1	15	17	PF00082	0.475
CLV_PCSK_KEX2_1	179	181	PF00082	0.497
CLV_PCSK_KEX2_1	226	228	PF00082	0.521
CLV_PCSK_KEX2_1	239	241	PF00082	0.385
CLV_PCSK_KEX2_1	26	28	PF00082	0.407
CLV_PCSK_KEX2_1	284	286	PF00082	0.383
CLV_PCSK_KEX2_1	295	297	PF00082	0.432
CLV_PCSK_KEX2_1	450	452	PF00082	0.398
CLV_PCSK_KEX2_1	470	472	PF00082	0.568
CLV_PCSK_KEX2_1	522	524	PF00082	0.496
CLV_PCSK_KEX2_1	611	613	PF00082	0.476
CLV_PCSK_KEX2_1	644	646	PF00082	0.586
CLV_PCSK_PC1ET2_1	102	104	PF00082	0.382
CLV_PCSK_PC1ET2_1	179	181	PF00082	0.437
CLV_PCSK_PC1ET2_1	284	286	PF00082	0.351
CLV_PCSK_PC1ET2_1	522	524	PF00082	0.406
CLV_PCSK_PC7_1	446	452	PF00082	0.376
CLV_PCSK_SKI1_1	139	143	PF00082	0.480
CLV_PCSK_SKI1_1	176	180	PF00082	0.439
CLV_PCSK_SKI1_1	26	30	PF00082	0.565
CLV_PCSK_SKI1_1	287	291	PF00082	0.484
CLV_PCSK_SKI1_1	361	365	PF00082	0.584
CLV_PCSK_SKI1_1	42	46	PF00082	0.390
CLV_PCSK_SKI1_1	498	502	PF00082	0.612
CLV_PCSK_SKI1_1	67	71	PF00082	0.339
CLV_PCSK_SKI1_1	701	705	PF00082	0.568
CLV_PCSK_SKI1_1	741	745	PF00082	0.649
CLV_Separin_Metazoa	350	354	PF03568	0.538
DEG_SCF_FBW7_1	355	362	PF00400	0.525
DOC_CKS1_1	706	711	PF01111	0.516
DOC_CYCLIN_RxL_1	176	187	PF00134	0.510
DOC_MAPK_gen_1	176	184	PF00069	0.511
DOC_MAPK_gen_1	328	338	PF00069	0.543
DOC_MAPK_gen_1	377	385	PF00069	0.502
DOC_MAPK_gen_1	644	653	PF00069	0.494
DOC_MAPK_gen_1	688	696	PF00069	0.552
DOC_MAPK_MEF2A_6	379	387	PF00069	0.463
DOC_MAPK_MEF2A_6	67	76	PF00069	0.387
DOC_USP7_MATH_1	359	363	PF00917	0.576
DOC_USP7_MATH_1	483	487	PF00917	0.420
DOC_USP7_MATH_1	531	535	PF00917	0.557
DOC_USP7_MATH_1	587	591	PF00917	0.374
DOC_USP7_MATH_1	753	757	PF00917	0.627
DOC_USP7_MATH_1	781	785	PF00917	0.689
DOC_USP7_MATH_1	792	796	PF00917	0.619
DOC_WW_Pin1_4	355	360	PF00397	0.661
DOC_WW_Pin1_4	418	423	PF00397	0.665
DOC_WW_Pin1_4	501	506	PF00397	0.466
DOC_WW_Pin1_4	668	673	PF00397	0.752
DOC_WW_Pin1_4	702	707	PF00397	0.766
DOC_WW_Pin1_4	710	715	PF00397	0.616
LIG_14-3-3_CanoR_1	138	144	PF00244	0.480
LIG_14-3-3_CanoR_1	216	221	PF00244	0.502
LIG_14-3-3_CanoR_1	26	31	PF00244	0.466
LIG_14-3-3_CanoR_1	262	272	PF00244	0.407
LIG_14-3-3_CanoR_1	450	459	PF00244	0.487
LIG_14-3-3_CanoR_1	471	481	PF00244	0.474
LIG_14-3-3_CanoR_1	498	508	PF00244	0.594
LIG_14-3-3_CanoR_1	539	549	PF00244	0.507
LIG_14-3-3_CanoR_1	629	634	PF00244	0.508
LIG_14-3-3_CanoR_1	67	76	PF00244	0.496
LIG_14-3-3_CanoR_1	741	749	PF00244	0.586
LIG_Actin_WH2_2	329	344	PF00022	0.436
LIG_Actin_WH2_2	435	452	PF00022	0.454
LIG_Actin_WH2_2	521	538	PF00022	0.482
LIG_Actin_WH2_2	560	577	PF00022	0.454
LIG_BIR_II_1	1	5	PF00653	0.611
LIG_BRCT_BRCA1_1	420	424	PF00533	0.570
LIG_CaM_IQ_9	130	146	PF13499	0.375
LIG_FHA_1	102	108	PF00498	0.373
LIG_FHA_1	114	120	PF00498	0.337
LIG_FHA_1	162	168	PF00498	0.383
LIG_FHA_1	29	35	PF00498	0.403
LIG_FHA_1	402	408	PF00498	0.692
LIG_FHA_1	43	49	PF00498	0.362
LIG_FHA_1	513	519	PF00498	0.641
LIG_FHA_1	541	547	PF00498	0.617
LIG_FHA_1	558	564	PF00498	0.343
LIG_FHA_1	661	667	PF00498	0.565
LIG_FHA_1	698	704	PF00498	0.588
LIG_FHA_1	742	748	PF00498	0.718
LIG_FHA_2	153	159	PF00498	0.503
LIG_FHA_2	187	193	PF00498	0.329
LIG_FHA_2	217	223	PF00498	0.502
LIG_FHA_2	305	311	PF00498	0.494
LIG_FHA_2	697	703	PF00498	0.533
LIG_LIR_Gen_1	566	574	PF02991	0.451
LIG_LIR_Gen_1	654	665	PF02991	0.488
LIG_LIR_Nem_3	247	253	PF02991	0.342
LIG_LIR_Nem_3	566	571	PF02991	0.570
LIG_LIR_Nem_3	654	660	PF02991	0.482
LIG_RPA_C_Fungi	183	195	PF08784	0.339
LIG_SH2_NCK_1	9	13	PF00017	0.473
LIG_SH2_STAP1	9	13	PF00017	0.473
LIG_SH2_STAT3	114	117	PF00017	0.522
LIG_SH2_STAT5	197	200	PF00017	0.508
LIG_SH2_STAT5	396	399	PF00017	0.471
LIG_SH2_STAT5	793	796	PF00017	0.542
LIG_SH2_STAT5	9	12	PF00017	0.476
LIG_SH3_2	706	711	PF14604	0.516
LIG_SH3_3	349	355	PF00018	0.655
LIG_SH3_3	502	508	PF00018	0.462
LIG_SH3_3	703	709	PF00018	0.707
LIG_SH3_3	791	797	PF00018	0.528
LIG_SUMO_SIM_anti_2	438	443	PF11976	0.377
LIG_TRAF2_1	318	321	PF00917	0.378
LIG_UBA3_1	656	662	PF00899	0.486
LIG_UBA3_1	703	711	PF00899	0.520
LIG_WRC_WIRS_1	588	593	PF05994	0.378
MOD_CDK_SPK_2	705	710	PF00069	0.514
MOD_CDK_SPxK_1	355	361	PF00069	0.527
MOD_CDK_SPxK_1	705	711	PF00069	0.528
MOD_CDK_SPxxK_3	710	717	PF00069	0.545
MOD_CK1_1	395	401	PF00069	0.551
MOD_CK1_1	417	423	PF00069	0.647
MOD_CK1_1	445	451	PF00069	0.558
MOD_CK1_1	547	553	PF00069	0.477
MOD_CK1_1	627	633	PF00069	0.613
MOD_CK1_1	7	13	PF00069	0.486
MOD_CK1_1	705	711	PF00069	0.587
MOD_CK1_1	713	719	PF00069	0.590
MOD_CK1_1	725	731	PF00069	0.632
MOD_CK2_1	159	165	PF00069	0.545
MOD_CK2_1	186	192	PF00069	0.332
MOD_CK2_1	216	222	PF00069	0.510
MOD_CK2_1	32	38	PF00069	0.545
MOD_CK2_1	449	455	PF00069	0.385
MOD_CK2_1	483	489	PF00069	0.408
MOD_CK2_1	696	702	PF00069	0.522
MOD_CK2_1	81	87	PF00069	0.415
MOD_GlcNHglycan	192	195	PF01048	0.377
MOD_GlcNHglycan	337	341	PF01048	0.515
MOD_GlcNHglycan	361	364	PF01048	0.518
MOD_GlcNHglycan	417	420	PF01048	0.557
MOD_GlcNHglycan	501	504	PF01048	0.463
MOD_GlcNHglycan	576	580	PF01048	0.396
MOD_GlcNHglycan	663	666	PF01048	0.666
MOD_GlcNHglycan	803	806	PF01048	0.650
MOD_GSK3_1	159	166	PF00069	0.479
MOD_GSK3_1	186	193	PF00069	0.466
MOD_GSK3_1	28	35	PF00069	0.555
MOD_GSK3_1	353	360	PF00069	0.786
MOD_GSK3_1	392	399	PF00069	0.451
MOD_GSK3_1	4	11	PF00069	0.623
MOD_GSK3_1	414	421	PF00069	0.613
MOD_GSK3_1	445	452	PF00069	0.494
MOD_GSK3_1	494	501	PF00069	0.520
MOD_GSK3_1	512	519	PF00069	0.657
MOD_GSK3_1	540	547	PF00069	0.471
MOD_GSK3_1	636	643	PF00069	0.627
MOD_GSK3_1	647	654	PF00069	0.581
MOD_GSK3_1	656	663	PF00069	0.576
MOD_GSK3_1	673	680	PF00069	0.555
MOD_GSK3_1	722	729	PF00069	0.727
MOD_GSK3_1	741	748	PF00069	0.787
MOD_GSK3_1	760	767	PF00069	0.486
MOD_GSK3_1	97	104	PF00069	0.398
MOD_N-GLC_1	139	144	PF02516	0.372
MOD_N-GLC_1	540	545	PF02516	0.378
MOD_N-GLC_1	660	665	PF02516	0.605
MOD_NEK2_1	1	6	PF00069	0.507
MOD_NEK2_1	184	189	PF00069	0.505
MOD_NEK2_1	196	201	PF00069	0.388
MOD_NEK2_1	256	261	PF00069	0.420
MOD_NEK2_1	336	341	PF00069	0.467
MOD_NEK2_1	383	388	PF00069	0.520
MOD_NEK2_1	449	454	PF00069	0.461
MOD_NEK2_1	636	641	PF00069	0.656
MOD_NEK2_1	65	70	PF00069	0.357
MOD_NEK2_1	660	665	PF00069	0.544
MOD_NEK2_1	696	701	PF00069	0.529
MOD_NEK2_1	760	765	PF00069	0.510
MOD_NEK2_2	531	536	PF00069	0.556
MOD_PIKK_1	113	119	PF00454	0.352
MOD_PIKK_1	132	138	PF00454	0.336
MOD_PIKK_1	304	310	PF00454	0.493
MOD_PIKK_1	353	359	PF00454	0.741
MOD_PIKK_1	396	402	PF00454	0.618
MOD_PIKK_1	42	48	PF00454	0.440
MOD_PIKK_1	469	475	PF00454	0.527
MOD_PIKK_1	547	553	PF00454	0.379
MOD_PIKK_1	636	642	PF00454	0.654
MOD_PKA_1	26	32	PF00069	0.407
MOD_PKA_2	152	158	PF00069	0.529
MOD_PKA_2	26	32	PF00069	0.407
MOD_PKA_2	341	347	PF00069	0.619
MOD_PKA_2	409	415	PF00069	0.534
MOD_PKA_2	445	451	PF00069	0.512
MOD_PKA_2	469	475	PF00069	0.564
MOD_Plk_1	139	145	PF00069	0.376
MOD_Plk_1	336	342	PF00069	0.460
MOD_Plk_1	544	550	PF00069	0.377
MOD_Plk_1	65	71	PF00069	0.339
MOD_Plk_4	163	169	PF00069	0.508
MOD_Plk_4	392	398	PF00069	0.438
MOD_Plk_4	435	441	PF00069	0.377
MOD_Plk_4	544	550	PF00069	0.375
MOD_Plk_4	716	722	PF00069	0.745
MOD_ProDKin_1	355	361	PF00069	0.663
MOD_ProDKin_1	418	424	PF00069	0.662
MOD_ProDKin_1	501	507	PF00069	0.465
MOD_ProDKin_1	668	674	PF00069	0.753
MOD_ProDKin_1	702	708	PF00069	0.764
MOD_ProDKin_1	710	716	PF00069	0.619
MOD_SUMO_for_1	389	392	PF00179	0.565
MOD_SUMO_rev_2	452	459	PF00179	0.554
TRG_AP2beta_CARGO_1	566	575	PF09066	0.513
TRG_DiLeu_BaEn_1	559	564	PF01217	0.351
TRG_DiLeu_BaEn_4	604	610	PF01217	0.390
TRG_DiLeu_LyEn_5	559	564	PF01217	0.351
TRG_ER_diArg_1	143	145	PF00400	0.391
TRG_ER_diArg_1	15	17	PF00400	0.466
TRG_ER_diArg_1	224	227	PF00400	0.521
TRG_ER_diArg_1	294	297	PF00400	0.453
TRG_ER_diArg_1	330	333	PF00400	0.563
TRG_ER_diArg_1	375	378	PF00400	0.478
TRG_ER_diArg_1	449	451	PF00400	0.419
TRG_ER_diArg_1	523	525	PF00400	0.479
TRG_ER_FFAT_2	3	14	PF00635	0.481
TRG_NES_CRM1_1	321	335	PF08389	0.378
TRG_NES_CRM1_1	367	381	PF08389	0.388
TRG_NES_CRM1_1	561	576	PF08389	0.509
TRG_NLS_MonoExtC_3	521	527	PF00514	0.395
TRG_NLS_MonoExtC_3	611	617	PF00514	0.551
TRG_NLS_MonoExtN_4	611	616	PF00514	0.392
TRG_Pf-PMV_PEXEL_1	180	185	PF00026	0.543
TRG_Pf-PMV_PEXEL_1	218	222	PF00026	0.527
TRG_Pf-PMV_PEXEL_1	296	300	PF00026	0.510
TRG_Pf-PMV_PEXEL_1	451	455	PF00026	0.390
TRG_Pf-PMV_PEXEL_1	562	566	PF00026	0.438

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFI1	Leptomonas seymouri	36%	85%
A0A3S7XC59	Leishmania donovani	57%	97%
A4IE13	Leishmania infantum	58%	97%
E9AU35	Leishmania mexicana (strain MHOM/GT/2001/U1103)	57%	82%
Q4Q0G0	Leishmania major	59%	100%