LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HQ97_LEIBR
TriTrypDb:
LbrM.35.6090 , LBRM2903_350072300 *
Length:
447

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HQ97
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HQ97

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 169 171 PF00675 0.573
CLV_NRD_NRD_1 274 276 PF00675 0.461
CLV_NRD_NRD_1 384 386 PF00675 0.709
CLV_NRD_NRD_1 388 390 PF00675 0.693
CLV_PCSK_KEX2_1 274 276 PF00082 0.484
CLV_PCSK_KEX2_1 386 388 PF00082 0.659
CLV_PCSK_PC1ET2_1 386 388 PF00082 0.659
CLV_PCSK_SKI1_1 267 271 PF00082 0.485
CLV_PCSK_SKI1_1 305 309 PF00082 0.511
CLV_PCSK_SKI1_1 311 315 PF00082 0.543
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PEF3 Leptomonas seymouri 44% 84%
A0A1X0NLI7 Trypanosomatidae 26% 100%
A0A3Q8IPS4 Leishmania donovani 70% 100%
A0A3R7NLX1 Trypanosoma rangeli 28% 100%
D0A414 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
E9AHY4 Leishmania infantum 71% 100%
E9AU15 Leishmania mexicana (strain MHOM/GT/2001/U1103) 71% 100%
Q4Q0I0 Leishmania major 69% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS