Adiponectin receptor protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

adiponectin receptor protein 1, putative

Species:

Leishmania braziliensis

UniProt:

A4HQ68_LEIBR

TriTrypDb:

LbrM.35.5790 , LBRM2903_350069300

Length:

337

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 21
NetGPI	no	yes: 0, no: 21

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	22
GO:0110165	cellular anatomical entity	1	22

Expansion

Sequence features

A4HQ68

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HQ68

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0038023	signaling receptor activity	2	2
GO:0060089	molecular transducer activity	1	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	37	39	PF00675	0.439
CLV_PCSK_KEX2_1	36	38	PF00082	0.398
CLV_PCSK_PC1ET2_1	36	38	PF00082	0.306
CLV_PCSK_SKI1_1	232	236	PF00082	0.354
CLV_PCSK_SKI1_1	265	269	PF00082	0.544
CLV_PCSK_SKI1_1	38	42	PF00082	0.318
CLV_PCSK_SKI1_1	93	97	PF00082	0.281
DEG_Nend_UBRbox_2	1	3	PF02207	0.514
DOC_MAPK_MEF2A_6	200	209	PF00069	0.287
DOC_MAPK_MEF2A_6	265	273	PF00069	0.241
DOC_PP4_FxxP_1	185	188	PF00568	0.305
DOC_PP4_FxxP_1	228	231	PF00568	0.529
DOC_PP4_FxxP_1	252	255	PF00568	0.231
DOC_PP4_FxxP_1	283	286	PF00568	0.343
DOC_USP7_MATH_1	49	53	PF00917	0.586
DOC_USP7_UBL2_3	89	93	PF12436	0.567
LIG_14-3-3_CanoR_1	43	51	PF00244	0.709
LIG_14-3-3_CanoR_1	83	92	PF00244	0.488
LIG_APCC_ABBA_1	96	101	PF00400	0.429
LIG_deltaCOP1_diTrp_1	287	294	PF00928	0.459
LIG_deltaCOP1_diTrp_1	295	304	PF00928	0.474
LIG_deltaCOP1_diTrp_1	70	77	PF00928	0.537
LIG_EH_1	74	78	PF12763	0.484
LIG_EH1_1	174	182	PF00400	0.269
LIG_eIF4E_1	264	270	PF01652	0.241
LIG_FHA_1	100	106	PF00498	0.439
LIG_FHA_1	112	118	PF00498	0.298
LIG_FHA_1	176	182	PF00498	0.329
LIG_FHA_1	204	210	PF00498	0.390
LIG_FHA_1	25	31	PF00498	0.636
LIG_FHA_1	258	264	PF00498	0.276
LIG_FHA_1	327	333	PF00498	0.451
LIG_FHA_2	4	10	PF00498	0.687
LIG_GBD_Chelix_1	116	124	PF00786	0.250
LIG_LIR_Apic_2	184	188	PF02991	0.304
LIG_LIR_Apic_2	225	231	PF02991	0.532
LIG_LIR_Gen_1	104	113	PF02991	0.416
LIG_LIR_Gen_1	131	142	PF02991	0.281
LIG_LIR_Gen_1	151	159	PF02991	0.231
LIG_LIR_Nem_3	104	109	PF02991	0.413
LIG_LIR_Nem_3	131	137	PF02991	0.254
LIG_LIR_Nem_3	151	157	PF02991	0.307
LIG_LIR_Nem_3	173	177	PF02991	0.305
LIG_LIR_Nem_3	184	189	PF02991	0.314
LIG_LYPXL_S_1	185	189	PF13949	0.400
LIG_LYPXL_yS_3	186	189	PF13949	0.400
LIG_NRBOX	119	125	PF00104	0.257
LIG_Pex14_2	219	223	PF04695	0.303
LIG_Pex14_2	92	96	PF04695	0.488
LIG_SH2_CRK	154	158	PF00017	0.501
LIG_SH2_CRK	236	240	PF00017	0.297
LIG_SH2_STAP1	8	12	PF00017	0.611
LIG_SH2_STAT3	281	284	PF00017	0.291
LIG_SH2_STAT3	290	293	PF00017	0.385
LIG_SH2_STAT5	134	137	PF00017	0.264
LIG_SH2_STAT5	174	177	PF00017	0.257
LIG_SH2_STAT5	191	194	PF00017	0.276
LIG_SH2_STAT5	203	206	PF00017	0.284
LIG_SH2_STAT5	281	284	PF00017	0.303
LIG_SH2_STAT5	316	319	PF00017	0.357
LIG_SH2_STAT5	86	89	PF00017	0.492
LIG_SUMO_SIM_anti_2	114	119	PF11976	0.157
LIG_SUMO_SIM_anti_2	194	201	PF11976	0.359
LIG_SUMO_SIM_anti_2	206	211	PF11976	0.432
LIG_SUMO_SIM_par_1	101	107	PF11976	0.539
LIG_SUMO_SIM_par_1	113	119	PF11976	0.260
LIG_SUMO_SIM_par_1	203	208	PF11976	0.394
LIG_SUMO_SIM_par_1	269	275	PF11976	0.164
LIG_TRAF2_1	29	32	PF00917	0.561
LIG_TYR_ITIM	172	177	PF00017	0.313
LIG_TYR_ITIM	234	239	PF00017	0.351
LIG_WRC_WIRS_1	182	187	PF05994	0.307
LIG_WRC_WIRS_1	219	224	PF05994	0.332
MOD_CK1_1	104	110	PF00069	0.332
MOD_CK1_1	194	200	PF00069	0.349
MOD_CK1_1	237	243	PF00069	0.389
MOD_CK2_1	26	32	PF00069	0.660
MOD_CK2_1	3	9	PF00069	0.708
MOD_CK2_1	64	70	PF00069	0.549
MOD_GlcNHglycan	157	160	PF01048	0.284
MOD_GSK3_1	149	156	PF00069	0.282
MOD_GSK3_1	194	201	PF00069	0.338
MOD_GSK3_1	218	225	PF00069	0.332
MOD_GSK3_1	234	241	PF00069	0.235
MOD_GSK3_1	253	260	PF00069	0.282
MOD_N-GLC_1	99	104	PF02516	0.250
MOD_NEK2_1	1	6	PF00069	0.684
MOD_NEK2_1	116	121	PF00069	0.332
MOD_NEK2_1	135	140	PF00069	0.342
MOD_NEK2_1	148	153	PF00069	0.241
MOD_NEK2_1	175	180	PF00069	0.233
MOD_NEK2_1	222	227	PF00069	0.512
MOD_NEK2_1	235	240	PF00069	0.298
MOD_NEK2_1	77	82	PF00069	0.431
MOD_NEK2_2	149	154	PF00069	0.272
MOD_NEK2_2	218	223	PF00069	0.400
MOD_NEK2_2	91	96	PF00069	0.444
MOD_PIKK_1	128	134	PF00454	0.215
MOD_PIKK_1	222	228	PF00454	0.490
MOD_PIKK_1	38	44	PF00454	0.662
MOD_PKA_2	326	332	PF00069	0.410
MOD_PKA_2	44	50	PF00069	0.709
MOD_Plk_1	1	7	PF00069	0.592
MOD_Plk_1	257	263	PF00069	0.323
MOD_Plk_1	63	69	PF00069	0.595
MOD_Plk_1	99	105	PF00069	0.481
MOD_Plk_2-3	64	70	PF00069	0.473
MOD_Plk_4	101	107	PF00069	0.486
MOD_Plk_4	111	117	PF00069	0.129
MOD_Plk_4	141	147	PF00069	0.343
MOD_Plk_4	149	155	PF00069	0.336
MOD_Plk_4	176	182	PF00069	0.323
MOD_Plk_4	194	200	PF00069	0.231
MOD_Plk_4	50	56	PF00069	0.546
MOD_Plk_4	77	83	PF00069	0.558
MOD_Plk_4	91	97	PF00069	0.548
TRG_ENDOCYTIC_2	134	137	PF00928	0.321
TRG_ENDOCYTIC_2	154	157	PF00928	0.425
TRG_ENDOCYTIC_2	174	177	PF00928	0.233
TRG_ENDOCYTIC_2	186	189	PF00928	0.301
TRG_ENDOCYTIC_2	236	239	PF00928	0.293
TRG_ENDOCYTIC_2	264	267	PF00928	0.296
TRG_ER_diArg_1	12	15	PF00400	0.628
TRG_ER_diArg_1	37	39	PF00400	0.571

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I280	Leptomonas seymouri	34%	94%
A0A0N1I909	Leptomonas seymouri	74%	100%
A0A0S4J7T5	Bodo saltans	37%	91%
A0A0S4J8V2	Bodo saltans	43%	100%
A0A0S4JQM0	Bodo saltans	47%	100%
A0A0S4JWI8	Bodo saltans	39%	100%
A0A0S4KIQ2	Bodo saltans	38%	100%
A0A1X0P1D6	Trypanosomatidae	38%	100%
A0A1X0P1Q2	Trypanosomatidae	37%	97%
A0A3R7L1Y6	Trypanosoma rangeli	35%	99%
A0A3S7XBT4	Leishmania donovani	34%	93%
A0A3S7XBU6	Leishmania donovani	39%	66%
A0A3S7XC05	Leishmania donovani	86%	100%
A4HQ63	Leishmania braziliensis	36%	100%
A4HQ67	Leishmania braziliensis	36%	100%
A4IDW4	Leishmania infantum	34%	93%
A4IDW5	Leishmania infantum	39%	66%
A4IDW6	Leishmania infantum	86%	100%
A8WZU4	Caenorhabditis briggsae	26%	80%
D0A450	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
D0A451	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	97%
E9ATY5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	93%
E9ATY6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	68%
E9ATY7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q03419	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	100%
Q09749	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	100%
Q09910	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	29%	76%
Q12442	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	100%
Q4Q0K9	Leishmania major	84%	100%
Q4Q0L0	Leishmania major	39%	66%
Q4Q0L1	Leishmania major	34%	100%
Q6TCG8	Mus musculus	33%	100%
Q6TCH7	Homo sapiens	32%	100%
Q753H5	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	27%	100%
Q75F81	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	23%	80%
Q801D8	Cynoscion nebulosus	24%	96%
Q801G2	Danio rerio	25%	95%
Q80ZE4	Mus musculus	27%	98%
Q84N34	Arabidopsis thaliana	28%	94%
Q86V24	Homo sapiens	36%	87%
Q86WK9	Homo sapiens	26%	97%
Q8BQS5	Mus musculus	36%	87%
Q8N4S7	Homo sapiens	28%	100%
Q91VH1	Mus musculus	34%	90%
Q93ZH9	Arabidopsis thaliana	35%	100%
Q94177	Caenorhabditis elegans	31%	78%
Q96A54	Homo sapiens	34%	90%
Q9DCU0	Mus musculus	25%	100%
Q9JJE4	Mus musculus	28%	100%
Q9NXK6	Homo sapiens	25%	100%
Q9VCY8	Drosophila melanogaster	35%	76%
Q9ZUH8	Arabidopsis thaliana	31%	98%
V5BJ57	Trypanosoma cruzi	37%	100%
V5DK49	Trypanosoma cruzi	38%	99%