39S ribosomal protein L39, mitochondrial

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HQ23_LEIBR

TriTrypDb:

LbrM.35.5320 , LBRM2903_350064100

Length:

392

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HQ23

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HQ23

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	329	331	PF00675	0.359
CLV_NRD_NRD_1	373	375	PF00675	0.364
CLV_NRD_NRD_1	57	59	PF00675	0.497
CLV_PCSK_FUR_1	55	59	PF00082	0.528
CLV_PCSK_KEX2_1	160	162	PF00082	0.438
CLV_PCSK_KEX2_1	329	331	PF00082	0.427
CLV_PCSK_KEX2_1	373	375	PF00082	0.440
CLV_PCSK_KEX2_1	57	59	PF00082	0.487
CLV_PCSK_PC1ET2_1	160	162	PF00082	0.389
CLV_PCSK_SKI1_1	10	14	PF00082	0.595
CLV_PCSK_SKI1_1	160	164	PF00082	0.404
CLV_PCSK_SKI1_1	373	377	PF00082	0.364
CLV_PCSK_SKI1_1	379	383	PF00082	0.392
CLV_PCSK_SKI1_1	46	50	PF00082	0.518
CLV_Separin_Metazoa	256	260	PF03568	0.478
DOC_CKS1_1	318	323	PF01111	0.356
DOC_MAPK_gen_1	248	257	PF00069	0.421
DOC_MAPK_gen_1	329	340	PF00069	0.399
DOC_MAPK_gen_1	34	42	PF00069	0.557
DOC_MAPK_gen_1	373	382	PF00069	0.366
DOC_MAPK_gen_1	97	105	PF00069	0.492
DOC_MAPK_MEF2A_6	376	384	PF00069	0.398
DOC_PP1_RVXF_1	208	215	PF00149	0.373
DOC_USP7_MATH_1	174	178	PF00917	0.447
DOC_USP7_MATH_1	293	297	PF00917	0.319
DOC_USP7_MATH_1	336	340	PF00917	0.233
DOC_WW_Pin1_4	250	255	PF00397	0.508
DOC_WW_Pin1_4	317	322	PF00397	0.323
LIG_14-3-3_CanoR_1	14	19	PF00244	0.545
LIG_14-3-3_CanoR_1	303	311	PF00244	0.556
LIG_14-3-3_CanoR_1	315	321	PF00244	0.377
LIG_14-3-3_CanoR_1	379	385	PF00244	0.418
LIG_BIR_II_1	1	5	PF00653	0.671
LIG_Clathr_ClatBox_1	368	372	PF01394	0.441
LIG_CSL_BTD_1	154	157	PF09270	0.400
LIG_FHA_1	223	229	PF00498	0.329
LIG_FHA_1	317	323	PF00498	0.359
LIG_FHA_1	87	93	PF00498	0.389
LIG_FHA_2	251	257	PF00498	0.519
LIG_GBD_Chelix_1	300	308	PF00786	0.301
LIG_LIR_Gen_1	116	125	PF02991	0.431
LIG_LIR_Gen_1	166	176	PF02991	0.466
LIG_LIR_Gen_1	73	79	PF02991	0.330
LIG_LIR_Nem_3	116	120	PF02991	0.400
LIG_LIR_Nem_3	166	172	PF02991	0.446
LIG_LIR_Nem_3	73	78	PF02991	0.340
LIG_PCNA_yPIPBox_3	329	341	PF02747	0.265
LIG_PTB_Apo_2	299	306	PF02174	0.386
LIG_PTB_Apo_2	340	347	PF02174	0.384
LIG_SH2_CRK	167	171	PF00017	0.357
LIG_SH2_GRB2like	233	236	PF00017	0.391
LIG_SH2_SRC	171	174	PF00017	0.370
LIG_SH2_STAP1	167	171	PF00017	0.386
LIG_SH2_STAP1	245	249	PF00017	0.306
LIG_SH2_STAT5	171	174	PF00017	0.356
LIG_SH2_STAT5	28	31	PF00017	0.559
LIG_SH3_2	292	297	PF14604	0.532
LIG_SH3_2	321	326	PF14604	0.361
LIG_SH3_3	142	148	PF00018	0.489
LIG_SH3_3	151	157	PF00018	0.452
LIG_SH3_3	205	211	PF00018	0.485
LIG_SH3_3	244	250	PF00018	0.415
LIG_SH3_3	285	291	PF00018	0.384
LIG_SH3_3	315	321	PF00018	0.329
LIG_SUMO_SIM_anti_2	253	260	PF11976	0.434
LIG_SUMO_SIM_anti_2	363	370	PF11976	0.360
LIG_SUMO_SIM_par_1	380	386	PF11976	0.432
LIG_TRAF2_1	179	182	PF00917	0.546
LIG_WRC_WIRS_1	368	373	PF05994	0.351
LIG_WW_2	292	295	PF00397	0.297
MOD_CK1_1	106	112	PF00069	0.568
MOD_CK1_1	113	119	PF00069	0.512
MOD_CK1_1	130	136	PF00069	0.560
MOD_CK1_1	137	143	PF00069	0.610
MOD_CK1_1	177	183	PF00069	0.387
MOD_CK1_1	275	281	PF00069	0.321
MOD_CK1_1	296	302	PF00069	0.444
MOD_CK2_1	106	112	PF00069	0.503
MOD_CK2_1	176	182	PF00069	0.516
MOD_CK2_1	250	256	PF00069	0.542
MOD_CK2_1	380	386	PF00069	0.417
MOD_GlcNHglycan	106	109	PF01048	0.479
MOD_GlcNHglycan	199	203	PF01048	0.424
MOD_GlcNHglycan	305	308	PF01048	0.587
MOD_GlcNHglycan	360	363	PF01048	0.416
MOD_GlcNHglycan	94	97	PF01048	0.449
MOD_GSK3_1	10	17	PF00069	0.537
MOD_GSK3_1	106	113	PF00069	0.562
MOD_GSK3_1	126	133	PF00069	0.445
MOD_GSK3_1	134	141	PF00069	0.579
MOD_GSK3_1	176	183	PF00069	0.403
MOD_GSK3_1	184	191	PF00069	0.456
MOD_GSK3_1	222	229	PF00069	0.330
MOD_GSK3_1	272	279	PF00069	0.365
MOD_LATS_1	44	50	PF00433	0.523
MOD_N-GLC_1	235	240	PF02516	0.497
MOD_NEK2_1	134	139	PF00069	0.655
MOD_NEK2_1	163	168	PF00069	0.446
MOD_NEK2_1	188	193	PF00069	0.539
MOD_NEK2_1	316	321	PF00069	0.360
MOD_NEK2_1	348	353	PF00069	0.292
MOD_NEK2_1	380	385	PF00069	0.504
MOD_NEK2_1	86	91	PF00069	0.423
MOD_NEK2_1	92	97	PF00069	0.404
MOD_PIKK_1	110	116	PF00454	0.453
MOD_PIKK_1	148	154	PF00454	0.414
MOD_PIKK_1	272	278	PF00454	0.425
MOD_PK_1	14	20	PF00069	0.550
MOD_PKA_2	296	302	PF00069	0.504
MOD_Plk_1	226	232	PF00069	0.357
MOD_Plk_1	235	241	PF00069	0.347
MOD_Plk_1	265	271	PF00069	0.571
MOD_Plk_1	49	55	PF00069	0.416
MOD_Plk_4	226	232	PF00069	0.372
MOD_Plk_4	336	342	PF00069	0.341
MOD_Plk_4	348	354	PF00069	0.434
MOD_Plk_4	49	55	PF00069	0.550
MOD_Plk_4	70	76	PF00069	0.363
MOD_ProDKin_1	250	256	PF00069	0.512
MOD_ProDKin_1	317	323	PF00069	0.323
TRG_DiLeu_BaEn_1	313	318	PF01217	0.462
TRG_DiLeu_BaEn_2	183	189	PF01217	0.336
TRG_DiLeu_BaLyEn_6	306	311	PF01217	0.517
TRG_DiLeu_BaLyEn_6	312	317	PF01217	0.340
TRG_DiLeu_BaLyEn_6	318	323	PF01217	0.312
TRG_ENDOCYTIC_2	167	170	PF00928	0.304
TRG_ENDOCYTIC_2	75	78	PF00928	0.351
TRG_ER_diArg_1	329	331	PF00400	0.423
TRG_ER_diArg_1	373	375	PF00400	0.440
TRG_ER_diArg_1	54	57	PF00400	0.537
TRG_Pf-PMV_PEXEL_1	46	50	PF00026	0.648

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HSQ0	Leptomonas seymouri	74%	99%
A0A0S4JP54	Bodo saltans	36%	80%
A0A1X0NDW4	Trypanosomatidae	50%	93%
A0A3Q8IHT7	Leishmania donovani	88%	100%
A0A3R7K3H2	Trypanosoma rangeli	56%	95%
A4IDT0	Leishmania infantum	88%	100%
D0A8U6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	53%	94%
E9ATU1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q0Q5	Leishmania major	86%	100%
V5AZJ2	Trypanosoma cruzi	54%	86%