Septin-type G domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HQ00_LEIBR

TriTrypDb:

LbrM.35.5080 , LBRM2903_350061700

Length:

479

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HQ00

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HQ00

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	185	187	PF00675	0.753
CLV_NRD_NRD_1	226	228	PF00675	0.521
CLV_NRD_NRD_1	40	42	PF00675	0.459
CLV_PCSK_KEX2_1	226	228	PF00082	0.521
CLV_PCSK_KEX2_1	268	270	PF00082	0.400
CLV_PCSK_KEX2_1	40	42	PF00082	0.459
CLV_PCSK_KEX2_1	92	94	PF00082	0.559
CLV_PCSK_PC1ET2_1	268	270	PF00082	0.400
CLV_PCSK_PC1ET2_1	92	94	PF00082	0.559
CLV_PCSK_SKI1_1	187	191	PF00082	0.446
CLV_PCSK_SKI1_1	227	231	PF00082	0.410
CLV_PCSK_SKI1_1	243	247	PF00082	0.496
CLV_PCSK_SKI1_1	272	276	PF00082	0.442
CLV_PCSK_SKI1_1	294	298	PF00082	0.618
CLV_PCSK_SKI1_1	35	39	PF00082	0.452
CLV_PCSK_SKI1_1	92	96	PF00082	0.463
DEG_APCC_DBOX_1	208	216	PF00400	0.549
DOC_CKS1_1	107	112	PF01111	0.734
DOC_CKS1_1	178	183	PF01111	0.548
DOC_CYCLIN_RxL_1	19	32	PF00134	0.390
DOC_CYCLIN_yClb5_NLxxxL_5	312	321	PF00134	0.717
DOC_CYCLIN_yCln2_LP_2	347	353	PF00134	0.541
DOC_CYCLIN_yCln2_LP_2	357	363	PF00134	0.563
DOC_MAPK_gen_1	268	276	PF00069	0.461
DOC_MAPK_gen_1	294	302	PF00069	0.520
DOC_PP1_RVXF_1	344	350	PF00149	0.573
DOC_PP1_RVXF_1	375	382	PF00149	0.439
DOC_USP7_MATH_1	137	141	PF00917	0.635
DOC_USP7_MATH_1	260	264	PF00917	0.689
DOC_WW_Pin1_4	106	111	PF00397	0.735
DOC_WW_Pin1_4	177	182	PF00397	0.739
DOC_WW_Pin1_4	246	251	PF00397	0.628
DOC_WW_Pin1_4	323	328	PF00397	0.641
DOC_WW_Pin1_4	60	65	PF00397	0.738
LIG_14-3-3_CanoR_1	186	190	PF00244	0.617
LIG_14-3-3_CanoR_1	226	235	PF00244	0.508
LIG_14-3-3_CanoR_1	240	246	PF00244	0.480
LIG_14-3-3_CanoR_1	422	428	PF00244	0.624
LIG_14-3-3_CanoR_1	93	98	PF00244	0.554
LIG_Actin_WH2_2	39	55	PF00022	0.440
LIG_Actin_WH2_2	463	479	PF00022	0.440
LIG_BIR_II_1	1	5	PF00653	0.728
LIG_deltaCOP1_diTrp_1	237	241	PF00928	0.482
LIG_EH1_1	401	409	PF00400	0.639
LIG_FHA_1	107	113	PF00498	0.559
LIG_FHA_1	20	26	PF00498	0.488
LIG_FHA_1	228	234	PF00498	0.510
LIG_FHA_1	297	303	PF00498	0.673
LIG_FHA_1	34	40	PF00498	0.441
LIG_FHA_1	81	87	PF00498	0.635
LIG_FHA_1	93	99	PF00498	0.561
LIG_FHA_2	309	315	PF00498	0.616
LIG_FHA_2	424	430	PF00498	0.459
LIG_FHA_2	94	100	PF00498	0.727
LIG_IRF3_LxIS_1	296	303	PF10401	0.521
LIG_LIR_Apic_2	133	139	PF02991	0.634
LIG_LIR_Apic_2	63	68	PF02991	0.573
LIG_LIR_Nem_3	125	129	PF02991	0.538
LIG_LIR_Nem_3	192	198	PF02991	0.508
LIG_LIR_Nem_3	201	207	PF02991	0.588
LIG_PTB_Apo_2	135	142	PF02174	0.567
LIG_PTB_Apo_2	211	218	PF02174	0.526
LIG_PTB_Phospho_1	211	217	PF10480	0.531
LIG_SH2_CRK	136	140	PF00017	0.575
LIG_SH2_CRK	217	221	PF00017	0.466
LIG_SH2_CRK	65	69	PF00017	0.571
LIG_SH2_GRB2like	136	139	PF00017	0.538
LIG_SH2_NCK_1	113	117	PF00017	0.791
LIG_SH2_NCK_1	136	140	PF00017	0.534
LIG_SH2_SRC	136	139	PF00017	0.538
LIG_SH2_SRC	402	405	PF00017	0.538
LIG_SH2_STAT3	142	145	PF00017	0.563
LIG_SH2_STAT3	160	163	PF00017	0.724
LIG_SH2_STAT5	234	237	PF00017	0.493
LIG_SH2_STAT5	402	405	PF00017	0.566
LIG_SH3_3	169	175	PF00018	0.551
LIG_SH3_3	99	105	PF00018	0.682
LIG_SUMO_SIM_anti_2	22	30	PF11976	0.514
LIG_SUMO_SIM_par_1	22	30	PF11976	0.514
LIG_TRAF2_1	426	429	PF00917	0.551
LIG_TYR_ITIM	215	220	PF00017	0.488
MOD_CDK_SPxK_1	177	183	PF00069	0.743
MOD_CK1_1	127	133	PF00069	0.674
MOD_CK1_1	140	146	PF00069	0.609
MOD_CK1_1	147	153	PF00069	0.719
MOD_CK1_1	168	174	PF00069	0.800
MOD_CK1_1	2	8	PF00069	0.746
MOD_CK1_1	228	234	PF00069	0.598
MOD_CK1_1	244	250	PF00069	0.397
MOD_CK1_1	261	267	PF00069	0.660
MOD_CK1_1	308	314	PF00069	0.694
MOD_CK1_1	326	332	PF00069	0.463
MOD_CK1_1	447	453	PF00069	0.570
MOD_CK2_1	278	284	PF00069	0.446
MOD_CK2_1	292	298	PF00069	0.549
MOD_CK2_1	308	314	PF00069	0.416
MOD_CK2_1	423	429	PF00069	0.467
MOD_CK2_1	451	457	PF00069	0.391
MOD_CMANNOS	238	241	PF00535	0.475
MOD_GlcNHglycan	129	132	PF01048	0.748
MOD_GlcNHglycan	246	249	PF01048	0.520
MOD_GlcNHglycan	280	283	PF01048	0.575
MOD_GlcNHglycan	303	306	PF01048	0.713
MOD_GlcNHglycan	333	336	PF01048	0.454
MOD_GlcNHglycan	4	7	PF01048	0.696
MOD_GlcNHglycan	58	61	PF01048	0.739
MOD_GSK3_1	108	115	PF00069	0.767
MOD_GSK3_1	137	144	PF00069	0.713
MOD_GSK3_1	147	154	PF00069	0.642
MOD_GSK3_1	185	192	PF00069	0.604
MOD_GSK3_1	225	232	PF00069	0.481
MOD_GSK3_1	251	258	PF00069	0.573
MOD_GSK3_1	260	267	PF00069	0.626
MOD_GSK3_1	29	36	PF00069	0.612
MOD_GSK3_1	292	299	PF00069	0.704
MOD_GSK3_1	301	308	PF00069	0.670
MOD_GSK3_1	338	345	PF00069	0.441
MOD_GSK3_1	447	454	PF00069	0.556
MOD_GSK3_1	48	55	PF00069	0.467
MOD_GSK3_1	56	63	PF00069	0.717
MOD_LATS_1	225	231	PF00433	0.510
MOD_N-GLC_1	105	110	PF02516	0.541
MOD_N-GLC_1	168	173	PF02516	0.799
MOD_N-GLC_1	447	452	PF02516	0.643
MOD_NEK2_1	112	117	PF00069	0.567
MOD_NEK2_1	119	124	PF00069	0.558
MOD_NEK2_1	141	146	PF00069	0.549
MOD_NEK2_1	198	203	PF00069	0.510
MOD_NEK2_1	229	234	PF00069	0.510
MOD_NEK2_1	275	280	PF00069	0.481
MOD_NEK2_1	292	297	PF00069	0.626
MOD_NEK2_1	300	305	PF00069	0.562
MOD_NEK2_1	418	423	PF00069	0.577
MOD_NEK2_1	47	52	PF00069	0.629
MOD_NEK2_1	98	103	PF00069	0.681
MOD_NEK2_2	124	129	PF00069	0.657
MOD_NEK2_2	241	246	PF00069	0.458
MOD_NEK2_2	48	53	PF00069	0.503
MOD_PIKK_1	141	147	PF00454	0.547
MOD_PIKK_1	275	281	PF00454	0.594
MOD_PIKK_1	328	334	PF00454	0.733
MOD_PKA_1	92	98	PF00069	0.613
MOD_PKA_2	185	191	PF00069	0.614
MOD_PKA_2	20	26	PF00069	0.548
MOD_PKA_2	225	231	PF00069	0.612
MOD_PKA_2	92	98	PF00069	0.609
MOD_Plk_1	168	174	PF00069	0.800
MOD_Plk_1	29	35	PF00069	0.622
MOD_Plk_1	308	314	PF00069	0.666
MOD_Plk_1	396	402	PF00069	0.383
MOD_Plk_1	447	453	PF00069	0.586
MOD_Plk_1	48	54	PF00069	0.461
MOD_Plk_1	98	104	PF00069	0.692
MOD_Plk_4	108	114	PF00069	0.513
MOD_Plk_4	137	143	PF00069	0.682
MOD_Plk_4	153	159	PF00069	0.622
MOD_Plk_4	185	191	PF00069	0.716
MOD_Plk_4	229	235	PF00069	0.502
MOD_Plk_4	251	257	PF00069	0.505
MOD_Plk_4	308	314	PF00069	0.708
MOD_Plk_4	33	39	PF00069	0.489
MOD_Plk_4	396	402	PF00069	0.383
MOD_Plk_4	66	72	PF00069	0.563
MOD_Plk_4	93	99	PF00069	0.582
MOD_ProDKin_1	106	112	PF00069	0.735
MOD_ProDKin_1	177	183	PF00069	0.737
MOD_ProDKin_1	246	252	PF00069	0.640
MOD_ProDKin_1	323	329	PF00069	0.637
MOD_ProDKin_1	60	66	PF00069	0.739
MOD_SUMO_for_1	431	434	PF00179	0.628
MOD_SUMO_rev_2	314	321	PF00179	0.618
TRG_ENDOCYTIC_2	204	207	PF00928	0.579
TRG_ENDOCYTIC_2	217	220	PF00928	0.469
TRG_ER_diArg_1	374	377	PF00400	0.724
TRG_ER_diArg_1	39	41	PF00400	0.460
TRG_Pf-PMV_PEXEL_1	40	44	PF00026	0.587

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I895	Leptomonas seymouri	56%	96%
A0A3Q8IRK5	Leishmania donovani	70%	100%
A4IDR1	Leishmania infantum	70%	100%
E9ATR7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	70%	100%
Q4Q0T0	Leishmania major	71%	100%