LeishMANIAdb
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PPR_long domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
PPR_long domain-containing protein
Gene product:
pentatricopeptide repeat domain containing protein, putative
Species:
Leishmania braziliensis
UniProt:
A4HPZ8_LEIBR
TriTrypDb:
LbrM.35.5060 , LBRM2903_350061500 *
Length:
278

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HPZ8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HPZ8

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 240 244 PF00656 0.449
CLV_NRD_NRD_1 166 168 PF00675 0.394
CLV_NRD_NRD_1 180 182 PF00675 0.444
CLV_NRD_NRD_1 47 49 PF00675 0.465
CLV_PCSK_KEX2_1 166 168 PF00082 0.394
CLV_PCSK_KEX2_1 180 182 PF00082 0.444
CLV_PCSK_KEX2_1 47 49 PF00082 0.454
CLV_PCSK_SKI1_1 121 125 PF00082 0.340
CLV_PCSK_SKI1_1 15 19 PF00082 0.421
CLV_PCSK_SKI1_1 180 184 PF00082 0.542
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I1J7 Leptomonas seymouri 82% 100%
A0A0S4IYI9 Bodo saltans 47% 100%
A0A1X0P0D8 Trypanosomatidae 60% 88%
A0A3Q8IJ22 Leishmania donovani 90% 100%
A0A3R7KPI7 Trypanosoma rangeli 57% 99%
A4IDQ9 Leishmania infantum 90% 100%
D0A4F1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 58% 71%
E9ATR5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
Q4Q0T2 Leishmania major 90% 100%
Q5BIV3 Arabidopsis thaliana 23% 76%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS