Putative cytochrome b5 1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cytochrome b5 1, putative

Species:

Leishmania braziliensis

UniProt:

A4HPY5_LEIBR

TriTrypDb:

LbrM.35.4930 , LBRM2903_350060100

Length:

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4HPY5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HPY5

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	2
GO:0020037	heme binding	4	2
GO:0046906	tetrapyrrole binding	3	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2
GO:0043167	ion binding	2	1
GO:0043169	cation binding	3	1
GO:0046872	metal ion binding	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	66	70	PF00082	0.314
DEG_Nend_UBRbox_1	1	4	PF02207	0.446
LIG_BRCT_BRCA1_1	52	56	PF00533	0.347
LIG_FHA_2	12	18	PF00498	0.234
LIG_FHA_2	3	9	PF00498	0.266
LIG_LIR_Gen_1	16	27	PF02991	0.293
LIG_LIR_Nem_3	16	22	PF02991	0.257
LIG_PCNA_TLS_4	66	73	PF02747	0.173
LIG_SH2_SRC	72	75	PF00017	0.173
LIG_SH2_STAT5	4	7	PF00017	0.287
LIG_SH2_STAT5	72	75	PF00017	0.351
LIG_TRAF2_1	5	8	PF00917	0.287
MOD_CK2_1	2	8	PF00069	0.287
MOD_GlcNHglycan	46	49	PF01048	0.389
MOD_NEK2_1	33	38	PF00069	0.275
MOD_PK_1	50	56	PF00069	0.325
MOD_Plk_2-3	58	64	PF00069	0.173
MOD_Plk_4	50	56	PF00069	0.347

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFL2	Leptomonas seymouri	56%	100%
A0A0S4JCD1	Bodo saltans	36%	68%
A0A0S4JHB7	Bodo saltans	43%	96%
A0A3S7XBN0	Leishmania donovani	80%	100%
A4IDP6	Leishmania infantum	80%	100%
E9ATQ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%
O22704	Arabidopsis thaliana	36%	68%
Q4Q0U6	Leishmania major	77%	100%